{"id":11483,"date":"2025-05-23T00:00:00","date_gmt":"2025-05-23T00:00:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e7%b2%be%e5%bd%a9%e9%a2%84%e5%91%8a-%e4%bc%a0%e5%a5%87%e7%94%9f%e7%89%a9%e5%b0%86%e5%9c%a82025asco%e3%80%81eha%e5%92%8casgct%e4%b8%8a%e5%85%ac%e5%b8%83%e8%82%bf%e7%98%a4%e5%92%8c%e8%a1%80%e6%b6%b2\/"},"modified":"2025-05-23T00:00:00","modified_gmt":"2025-05-23T00:00:00","slug":"%e7%b2%be%e5%bd%a9%e9%a2%84%e5%91%8a-%e4%bc%a0%e5%a5%87%e7%94%9f%e7%89%a9%e5%b0%86%e5%9c%a82025asco%e3%80%81eha%e5%92%8casgct%e4%b8%8a%e5%85%ac%e5%b8%83%e8%82%bf%e7%98%a4%e5%92%8c%e8%a1%80%e6%b6%b2","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e7%b2%be%e5%bd%a9%e9%a2%84%e5%91%8a-%e4%bc%a0%e5%a5%87%e7%94%9f%e7%89%a9%e5%b0%86%e5%9c%a82025asco%e3%80%81eha%e5%92%8casgct%e4%b8%8a%e5%85%ac%e5%b8%83%e8%82%bf%e7%98%a4%e5%92%8c%e8%a1%80%e6%b6%b2\/","title":{"rendered":"\u7cbe\u5f69\u9884\u544a | \u4f20\u5947\u751f\u7269\u5c06\u57282025ASCO\u3001EHA\u548cASGCT\u4e0a\u516c\u5e03\u80bf\u7624\u548c\u8840\u6db2\u6cbb\u7597\u9886\u57df\u6700\u65b0\u8fdb\u5c55"},"content":{"rendered":"

CARTITUDE-1\u7814\u7a76\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff0c\u91cd\u70b9\u5c55\u793a\u7ecf\u591a\u7ebf\u6cbb\u7597\u7684\u9aa8\u9ad3\u7624\u60a3\u8005\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u8d85\u8fc75\u5e74\u7684\u957f\u671f\u7597\u6548\u5728ASCO\u516c\u5e03\u7684CARTITUDE-4\u7814\u7a76\u65b0\u6570\u636e\u8868\u660e\uff0c\u5728\u5173\u952e\u4e9a\u7ec4\u5206\u6790\u4e2d\uff0cCARVYKTI\u00ae\u76f8\u8f83\u6807\u51c6\u6cbb\u7597\u65b9\u6848\uff08SOC\uff09\u80fd\u663e\u8457\u6539\u5584\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\u6b63\u5728\u8fdb\u884c\u7684\u6cbb\u7597\u80ba\u764c\u7684LB2102\u548c\u6cbb\u7597\u80c3\u98df\u7ba1\u764c\u7684LB1908 I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u521d\u6b65\u7ed3\u679c\u5c06\u5728ASCO\u4f1a\u8bae\u4e0a\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793aLB2102\u7814\u7a76\u6570\u636e\u8fd1\u671f\u4ea6\u5728\u7f8e\u56fd\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ASGCT\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03<\/p>\n

\u5357\u4eac<\/span>2025\u5e745\u670823\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u5f53\u5730\u65f6\u95f42025\u5e745\u670822\u65e5\uff0c\u4f20\u5947\u751f\u7269\uff08NASDAQ: LEGN\uff09\u5728\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u8428\u9ed8\u585e\u7279\u5ba3\u5e03\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u548c2025\u5e74\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684CARVYKTI\u00ae\uff08\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff0ccilta-cel\uff09\u6700\u65b0\u7814\u7a76\u6570\u636e\u3002\u6b64\u5916\uff0c\u4f20\u5947\u751f\u7269\u5728\u5b9e\u4f53\u7624\u9886\u57df\u7684\u4e24\u9879I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u2014\u2014LB2102\uff08\u7528\u4e8e\u6cbb\u7597\u80ba\u764c\uff09\u548cLB1908\uff08\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\uff09\u7684\u521d\u6b65\u7ed3\u679c\u4e5f\u5c06\u5728ASCO\u4f1a\u8bae\u7684\u58c1\u62a5\u5c55\u793a\u73af\u8282\u4e2d\u4eae\u76f8\u3002<\/p>\n

\n

\n <\/a><\/p>\n

\n <\/p>\n<\/div>\n

\u4f20\u5947\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u9ec4\u9896\u535a\u58eb\u8868\u793a\uff1a “\u6211\u4eec\u5f88\u9ad8\u5174\u5728ASCO\u548cEHA\u4e0a\u5c55\u793a\u7684\u6700\u65b0\u6570\u636e\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86CARVYKTI\u00ae\u5728\u591a\u53d1\u6027\u9aa8\u9ad3\u7624CAR-T\u6cbb\u7597\u9886\u57df\u7684\u5e02\u573a\u9886\u5148\u5730\u4f4d\u3002\u8fc4\u4eca\u5df2\u6cbb\u7597\u8d85\u8fc76500\u4f8b\u60a3\u8005\uff0c\u5176\u65e5\u76ca\u663e\u8457\u7684\u4e34\u5e8a\u6548\u679c\u663e\u800c\u6613\u89c1\u3002\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u975e\u5e38\u671f\u5f85\u901a\u8fc7\u80ba\u764c\u548c\u80c3\u764c\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u6765\u5c55\u73b0\u516c\u53f8\u66f4\u5e7f\u6cdb\u7684\u7814\u53d1\u7ba1\u7ebf\u8fdb\u5c55\u2014\u2014\u6807\u5fd7\u7740\u6211\u4eec\u5728\u62d3\u5c55\u7ec6\u80de\u7597\u6cd5\u65b0\u7586\u754c\u8fc8\u51fa\u4e86\u91cd\u8981\u4e00\u6b65\u3002”<\/p>\n

CARVYKTI\u00ae\u6570\u636e<\/p>\n

\u6765\u81eaCARTITUDE-1\u7814\u7a76\u7684\u957f\u671f\u968f\u8bbf\u6570\u636e\u5c06\u5728ASCO\u5927\u4f1a\u4e0a\u9996\u6b21\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\uff0c\u5e76\u968f\u540e\u5728EHA\u5927\u4f1a\u4e0a\u518d\u6b21\u8fdb\u884c\u53e3\u5934\u62a5\u544a\u3002\u8be5\u7814\u7a76\u8bc4\u4f30\u4e86CARVYKTI\u00ae\u5728\u7ecf\u91cd\u5ea6\u9884\u5904\u7406\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u4e2d\u7684\u7597\u6548\u3002<\/span>\u8fd9\u4e9b\u60a3\u8005\u65e2\u5f80\u7684\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e0d\u8db36\u4e2a\u6708\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u7ea6\u4e3a1\u5e74\u3002\u672c\u6b21\u62a5\u544a\u5c06\u5c55\u793a\u4e2d\u4f4d\u968f\u8bbf60.3\u4e2a\u6708\u7684\u5173\u952e\u6570\u636e\uff0c\u5305\u62ec\u603b\u751f\u5b58\u671f\u3001\u8d85\u8fc75\u5e74\u65e0\u8fdb\u5c55\u751f\u5b58\u7684\u7ed3\u679c\u548c\u5b89\u5168\u6027\u6570\u636e\u3002\u5728\u7814\u7a76\u4e2d\uff0c\u90a3\u4e9b\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u7684\u60a3\u8005\u5728\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\uff0c\u672a\u518d\u63a5\u53d7\u5176\u4ed6\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6cbb\u7597\u3002<\/p>\n

CARTITUDE-4\u7814\u7a76\u7684\u610f\u5411\u6027\u6cbb\u7597\uff08ITT\uff09\u4e9a\u7ec4\u5206\u6790\u6570\u636e\u5c06\u5728ASCO\u5e74\u4f1a\u4e0a\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793a\u3002\u8fd9\u4e9b\u4e9a\u7ec4\u5305\u62ec\u5177\u6709\u9ad8\u5371\u7ec6\u80de\u9057\u4f20\u5b66\u7279\u5f81\u7684\u60a3\u8005\u4ee5\u53ca\u4f34\u9ad3\u5916\u75c5\u53d8\uff08EMD\uff09\u5e76\u63a5\u53d7\u8fc7\u4e00\u7ebf\u6cbb\u7597\u7684\u60a3\u8005\u3002\u8be5\u6570\u636e\u6301\u7eed\u652f\u6301\u4e86CARVYKTI\u00ae\u5728\u5404\u4e2a\u4e9a\u7ec4\u4e2d\u53ca\u6700\u65e9\u5728\u9996\u6b21\u590d\u53d1\u540e\u5177\u6709\u79ef\u6781\u7684\u83b7\u76ca-\u98ce\u9669\u6bd4\u3002<\/p>\n

EHA\u5e74\u4f1a\u4e0a\u5c06\u4ee5\u58c1\u62a5\u5f62\u5f0f\u53d1\u8868\u4e00\u9879\u751f\u7269\u6807\u5fd7\u7269\u5206\u6790\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u63a2\u8ba8\u4e86CARVYKTI\u00ae\u6cbb\u7597\u540e\u51fa\u73b0\u7684\u8fd0\u52a8\u53ca\u795e\u7ecf\u8ba4\u77e5\u4e0d\u826f\u4e8b\u4ef6\uff08MNT\uff09\u548c\u9885\u795e\u7ecf\u9ebb\u75f9\uff08CNP\uff09\u4e0e\u7279\u5b9a\u751f\u7269\u6807\u5fd7\u7269\u7684\u76f8\u5173\u6027\u3002<\/p>\n

\u5b9e\u4f53\u7624\u7ba1\u7ebf<\/p>\n

ASCO\u5e74\u4f1a\u58c1\u62a5\u73af\u8282\u5c06\u5c55\u793a\u4e24\u9879\u6b63\u5728\u8fdb\u884c\u4e2d\u7684I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u7684\u521d\u6b65\u7ed3\u679c\uff1a\u5206\u522b\u4e3a\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u548c\u5927\u7ec6\u80de\u795e\u7ecf\u5185\u5206\u6ccc\u764c\uff08LCNEC\uff09\u7684dnTGF\u03b2RII\u88c5\u7532\u9776\u5411DLL3\u81ea\u4f53CAR-T\u7ec6\u80de\u7597\u6cd5LB2102\uff0c\u4ee5\u53ca\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u98df\u7ba1\u817a\u764c\u7684\u9776\u5411Claudin 18.2\u81ea\u4f53CAR-T\u7597\u6cd5LB1908\u3002<\/p>\n

\u6b63\u5728\u8fdb\u884c\u7684LB2102 I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u6570\u636e\u5df2\u4e8e5\u670816\u65e5\u5728\u7b2c28\u5c4a\u7f8e\u56fd\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ASGCT\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u4e86\u53e3\u5934\u62a5\u544a\u3002<\/p>\n

2023\u5e7411\u6708\uff0c\u6211\u4eec\u4e0e\u8bfa\u534e\u5236\u836f\uff08Novartis Pharma AG\uff09\u5c31\u5305\u62ecLB2102\u5728\u5185\u7684\u7279\u5b9a\u9776\u5411DLL3\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u8fbe\u6210\u4e86\u72ec\u5bb6\u5168\u7403\u8bb8\u53ef\u534f\u8bae\u3002<\/p>\n

\u6839\u636e\u8bb8\u53ef\u534f\u8bae\uff0c\u6211\u4eec\u5c06\u5728\u7f8e\u56fd\u8fdb\u884cLB2102\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bfa\u534e\u8d1f\u8d23\u8bb8\u53ef\u4ea7\u54c1\u7684\u6240\u6709\u5176\u4ed6\u5f00\u53d1\u3002<\/p>\n

\u00a0<\/p>\n

2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u62a5\u544a
\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f62025\u5e745\u670830\u65e5-6\u67083\u65e5\uff09<\/p>\n

1\u3001\u6458\u8981\u7f16\u53f7\uff1a#7507 \u53e3\u5934\u62a5\u544a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aLong-term (\u22655 year) remission and survival after treatment with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 patients (pts) with relapsed\/refractory multiple myeloma (RRMM)\u00a0
CARTITUDE-1\u7814\u7a76\u4e2d\u63a5\u53d7\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u6cbb\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08RRMM\uff09\u60a3\u8005\u7684\u957f\u671f\uff08\u22655\u5e74\uff09\u7f13\u89e3\u4e0e\u751f\u5b58\u60c5\u51b5<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u4e3b\u9898\uff1a\u6076\u6027\u8840\u6db2\u80bf\u7624\u2014\u6d46\u7ec6\u80de\u75c5<\/span>
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u67083\u65e5\u4e0a\u534811:57-\u4e0b\u534812:09\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1aS100bc<\/p>\n

2\u3001\u6458\u8981\u7f16\u53f7\uff1a#7539 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aCiltacabtagene autoleucel (cilta-cel) vs standard of care (SOC) in patients (pts) with relapsed\/refractory multiple myeloma (MM): CARTITUDE-4 survival subgroup analyses
\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u4e0e\u6807\u51c6\u6cbb\u7597\uff08SOC\uff09\u5728\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08MM\uff09\u60a3\u8005\u4e2d\u7684\u7597\u6548\u5bf9\u6bd4\uff1aCARTITUDE-4\u751f\u5b58\u4e9a\u7ec4\u5206\u6790<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u4e3b\u9898\uff1a\u6076\u6027\u8840\u6db2\u80bf\u7624\u2014\u6d46\u7ec6\u80de\u75c5<\/span>
\u58c1\u62a5\u7f16\u53f7\uff1a107
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u67081\u65e5\u4e0a\u53489:00 -12:00\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1aA\u5385<\/p>\n

3\u3001\u6458\u8981\u7f16\u53f7\uff1a#4022 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aPreliminary results of a phase 1 study of LB1908, an autologous Claudin 18.2-targeted chimeric antigen receptor T-cell product, in patients with advanced gastroesophageal adenocarcinoma
\u81ea\u4f53\u9776\u5411Claudin 18.2\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u4ea7\u54c1LB1908\u5728\u665a\u671f\u80c3\u98df\u7ba1\u817a\u764c\u60a3\u8005\u4e2d\u7684I\u671f\u7814\u7a76\u521d\u6b65\u7ed3\u679c<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u4e3b\u9898\uff1a\u80c3\u80a0\u9053\u764c\u2014\u80c3\u98df\u7ba1\u3001\u80f0\u817a\u53ca\u809d\u80c6\u80bf\u7624
\u58c1\u62a5\u7f16\u53f7\uff1a312
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e745\u670831\u65e5\u4e0a\u53489:00-12:00\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1aA\u5385<\/p>\n

4\u3001\u6458\u8981\u7f16\u53f7\uff1a#8104 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aSafety, tolerability, and preliminary efficacy results of a phase 1 study of LB2102, a dnTGF\u00dfRII Armored DLL3-targeted autologous CAR-T cell therapy, in patients with relapsed or refractory small-cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC)
LB2102\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\uff1adnTGF\u03b2RII\u88c5\u7532\u9776\u5411DLL3 CAR-T\u7ec6\u80de\u7597\u6cd5\u5728\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u548c\u5927\u7ec6\u80de\u795e\u7ecf\u5185\u5206\u6ccc\u764c\uff08LCNEC\uff09\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u53ca\u521d\u6b65\u7597\u6548\u6570\u636e<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u4e3b\u9898\uff1a\u80ba\u764c\u2014\u975e\u5c0f\u7ec6\u80de\u5c40\u90e8\u533a\u57df\u6027\u75be\u75c5\/\u5c0f\u7ec6\u80de\u53ca\u5176\u4ed6\u80f8\u90e8\u80bf\u7624
\u58c1\u62a5\u7f16\u53f7\uff1a225
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e745\u670831\u65e5\u4e0b\u53481:30 – 4:30\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1aA\u5385<\/p>\n

2025\u5e74\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u62a5\u544a
\uff08\u6b27\u6d32\u4e2d\u90e8\u590f\u4ee4\u65f62025\u5e746\u670812\u65e5-15\u65e5\uff09<\/p>\n

1\u3001\u6458\u8981\u7f16\u53f7\uff1a#S192 \u53e3\u5934\u62a5\u544a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aEncore: Long-term (\u22655 year) remission and survival after treatment with ciltacabtagene autoleucel in CARTITUDE-1 patients with relapsed\/refractory multiple myeloma
CARTITUDE-1\u7814\u7a76\u4e2d\u63a5\u53d7\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u6cbb\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08RRMM\uff09\u60a3\u8005\u7684\u957f\u671f\uff08\u22655\u5e74\uff09\u7f13\u89e3\u4e0e\u751f\u5b58\u60c5\u51b5<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u5206\u4f1a\u573a\uff1as410 \u6dcb\u5df4\u7cfb\u7edf\u6076\u6027\u80bf\u7624\u4e34\u5e8a\u8bd5\u9a8c\u957f\u671f\u968f\u8bbf
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u670812\u65e517:00-18:15\uff08\u6b27\u6d32\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1a\u91d1\u8272\u5385<\/p>\n

2\u3001\u6458\u8981\u7f16\u53f7\uff1a#PS1723 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aEncore: Ciltacabtagene autoleucel vs standard of care in patients with relapsed\/refractory multiple myeloma: CARTITUDE-4 survival subgroup analyses
\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u4e0e\u6807\u51c6\u6cbb\u7597\uff08SOC\uff09\u5728\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08MM\uff09\u60a3\u8005\u4e2d\u7684\u7597\u6548\u5bf9\u6bd4\uff1aCARTITUDE-4\u751f\u5b58\u4e9a\u7ec4\u5206\u6790<\/p>\n

\u4f1a\u8bae\u4fe1\u606f
\u5206\u4f1a\u573a\uff1a\u58c1\u62a5\u73af\u82822
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u670814\u65e518:30-19:30\uff08\u6b27\u6d32\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1a\u58c1\u62a5\u5385<\/p>\n

3\u3001\u6458\u8981\u7f16\u53f7\uff1a#PS1728 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aAbsolute Lymphocyte Count as a Key Biomarker for Monitoring Safety After Ciltacabtagene Autoleucel
\u6dcb\u5df4\u7ec6\u80de\u7edd\u5bf9\u503c\u4f5c\u4e3a\u5173\u952e\u751f\u7269\u6807\u5fd7\u7269\u5bf9\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u6cbb\u7597\u540e\u7684\u5b89\u5168\u6027\u76d1\u6d4b\u4ef7\u503c<\/p>\n

\u4f1a\u8bae\u4fe1\u606f
\u5206\u4f1a\u573a\uff1a\u58c1\u62a5\u73af\u82822
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u670814\u65e518:30-19:30\uff08\u6b27\u6d32\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1a\u58c1\u62a5\u5385<\/p>\n

4\u3001\u6458\u8981\u7f16\u53f7\uff1a#PF765 \u58c1\u62a5\u5c55\u793a<\/p>\n

\u6458\u8981\u6807\u9898\uff1aSurvival Benefit of Ciltacabtagene Autoleucel in Second Line Compared with Later-Line Treatment of Lenalidomide-Refractory Multiple Myeloma: Updated Treatment Positioning Model Analysis
\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u4e8c\u7ebf\u6cbb\u7597\u4e0e\u540e\u7ebf\u6cbb\u7597\u5728\u6765\u90a3\u5ea6\u80fa\u8010\u836f\u7684\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u4e2d\u7684\u751f\u5b58\u83b7\u76ca\u6bd4\u8f83\uff1a\u6cbb\u7597\u5b9a\u4f4d\u6a21\u578b\u5206\u6790\u7ed3\u679c\u66f4\u65b0<\/p>\n

\u4f1a\u8bae\u4fe1\u606f
\u5206\u4f1a\u573a\uff1a\u58c1\u62a5\u73af\u82821
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u670813\u65e518:30-19:30\uff08\u6b27\u6d32\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1a\u58c1\u62a5\u5385<\/p>\n

2025\u5e74\u7f8e\u56fd\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ASGCT\uff09\u62a5\u544a
\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f62025\u5e745\u670813\u65e5-17\u65e5\uff09<\/p>\n

1\u3001\u6458\u8981\u7f16\u53f7\uff1a#339 \u53e3\u5934\u62a5\u544a<\/p>\n

\u6458\u8981\u6807\u9898\uff1adnTGF\u03b2RII-Armored DLL3-Targeted CAR-T Cells Maintain TGF\u03b2 Resistance with Early Signals of T-Cell Exhaustion Modulation After Expansion in SCLC
dnTGF\u03b2RII\u88c5\u7532\u9776\u5411DLL3 \u7684CAR-T\u7ec6\u80de\u6269\u589e\u540e\u5728\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u4e2d\u7ef4\u6301TGF\u03b2\u6297\u6027\u5e76\u663e\u793aT\u7ec6\u80de\u8017\u7aed\u8c03\u63a7\u7684\u65e9\u671f\u4fe1\u53f7<\/p>\n

\u4f1a\u8bae\u4fe1\u606f\uff1a
\u5206\u4f1a\u573a\uff1a\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u5de5\u7a0bII
\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e745\u670816\u65e5\u4e0b\u53483:45 – 5:40\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u62a5\u544a\u65f6\u95f4\uff1a\u4e0b\u53484:00 – 4:15\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09
\u5730\u70b9\uff1a293-296\u4f1a\u8bae\u5ba4<\/p>\n

\u00a0<\/p>\n

\u5173\u4e8eCARVYKTI\u00ae\uff08Cilta-cel\uff0c\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff09<\/p>\n

\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u662f\u4e00\u79cd\u9776\u5411B\u7ec6\u80de\u6210\u719f\u6297\u539f\uff08BCMA\uff09\u7684\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\uff08CAR-T\uff09\u7597\u6cd5\uff0c\u4f7f\u7528\u5d4c\u5408\u6297\u539f\u53d7\u4f53\uff08CAR\uff09\u7684\u8f6c\u57fa\u56e0\u7f16\u8f91\u5bf9\u60a3\u8005\u81ea\u8eab\u7684T\u7ec6\u80de\u8fdb\u884c\u4fee\u9970\uff0c\u4ee5\u8bc6\u522b\u548c\u6d88\u9664\u8868\u8fbeBCMA\u7684\u7ec6\u80de\u3002\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u7684CAR\u86cb\u767d\u5177\u6709\u4e24\u4e2a\u9776\u5411BCMA\u7684\u5355\u57df\u6297\u4f53\uff0c\u5bf9\u8868\u8fbeBCMA\u7684\u7ec6\u80de\u5177\u6709\u9ad8\u4eb2\u548c\u529b\uff0c\u5728\u4e0e\u8868\u8fbeBCMA\u7684\u7ec6\u80de\u7ed3\u5408\u540e\uff0cCAR\u53ef\u4fc3\u8fdbT\u7ec6\u80de\u6d3b\u5316\u3001\u6269\u589e\uff0c\u7ee7\u800c\u6e05\u9664\u9776\u7ec6\u80de[1]\u3002<\/p>\n

2017\u5e7412\u6708\uff0c\u6768\u68ee\u4e0e\u4f20\u5947\u751f\u7269\u7b7e\u8ba2\u4e86\u5168\u7403\u72ec\u5bb6\u8bb8\u53ef\u548c\u5408\u4f5c\u534f\u8bae\uff0c\u4ee5\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u30022022\u5e742\u6708\uff0c\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u4e0a\u5e02\uff0c5\u6708\u83b7\u5f97\u6b27\u76df\u59d4\u5458\u4f1a\uff08EC\uff09\u6388\u4e88\u7684\u9644\u6761\u4ef6\u4e0a\u5e02\u8bb8\u53ef\uff0c9\u6708\u83b7\u5f97\u65e5\u672c\u539a\u751f\u52b3\u52a8\u7701\uff08MHLW\uff09\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6210\u4eba\u60a3\u8005\uff0c\u5546\u54c1\u540d\u4e3aCARVYKTI\u00ae\u30022024\u5e744\u6708\uff0c\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u5148\u540e\u88ab\u7f8e\u56fdFDA\u3001\u6b27\u76df\u59d4\u5458\u4f1a\u6279\u51c6\u7528\u4e8e\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u7684\u4e8c\u7ebf\u6cbb\u7597\uff0c\u8fd9\u4e9b\u60a3\u8005\u9700\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e00\u7ebf\u6cbb\u7597\uff0c\u5305\u62ec\u4e00\u79cd\u86cb\u767d\u9176\u4f53\u6291\u5236\u5242\uff08PI\uff09\u548c\u4e00\u79cd\u514d\u75ab\u8c03\u8282\u5242\uff08IMiD\uff09\u4e14\u5bf9\u6765\u90a3\u5ea6\u80fa\u8010\u836f\u30022024\u5e748\u6708\uff0c\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e09\u7ebf\u6cbb\u7597\u540e\u8fdb\u5c55\uff08\u81f3\u5c11\u4f7f\u7528\u8fc7\u4e00\u79cd\u86cb\u767d\u9176\u4f53\u6291\u5236\u5242\u53ca\u514d\u75ab\u8c03\u8282\u5242\uff09\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6210\u4eba\u60a3\u8005\u3002<\/p>\n

\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u4e8e2019\u5e7412\u6708\u5728\u7f8e\u56fd\u548c2020\u5e748\u6708\u5728\u4e2d\u56fd\u83b7\u5f97\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002\u6b64\u5916\uff0c\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u4e8e2019\u5e744\u6708\u83b7\u5f97\u6b27\u76df\u59d4\u5458\u4f1a\u4f18\u5148\u836f\u7269\u8d44\u683c\u8ba4\u5b9a\u3002\u7f8e\u56fdFDA\u3001\u6b27\u6d32EMA\u548c\u65e5\u672cPMDA\u5206\u522b\u4e8e2019\u5e742\u6708\u30012020\u5e742\u6708\u53ca2020\u5e746\u6708\u6388\u4e88\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u30022022\u5e743\u6708\uff0c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u7684\u5b64\u513f\u836f\u54c1\u59d4\u5458\u4f1a\u4e00\u81f4\u5efa\u8bae\uff0c\u6839\u636e\u4e34\u5e8a\u6570\u636e\uff08\u6cbb\u7597\u540e\u66f4\u597d\u4e14\u6301\u7eed\u7684\u5b8c\u5168\u7f13\u89e3\u7387\uff09\u7ef4\u6301\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u7684\u5b64\u513f\u836f\u8ba4\u5b9a\u3002<\/p>\n

\u5173\u4e8eCARTITUDE-1<\/span><\/p>\n

CARTITUDE-1\uff08NCT03548207\uff09\u662f\u4e00\u98791b\/2\u671f\u3001\u5f00\u653e\u6807\u7b7e\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8bc4\u4f30\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u5728\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u8be5\u7814\u7a76\u5165\u7ec4\u60a3\u8005\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7\u8fc7\u4e09\u7ebf\u7597\u6cd5\uff08\u5305\u62ec\u86cb\u767d\u9176\u4f53\u6291\u5236\u5242[PI]\u3001\u514d\u75ab\u8c03\u8282\u5242[IMiD]\u548c\u6297CD38\u5355\u514b\u9686\u6297\u4f53\uff09\u6216\u5bf9PI\u3001IMiD\u53cc\u91cd\u8010\u836f\uff0c \u4e14\u5728\u6700\u8fd1\u4e00\u6b21\u6cbb\u7597\u5f00\u59cb\u540e12\u4e2a\u6708\u5185\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u30021b\u671f\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u6807\u662f\u8bc4\u4f30\u836f\u7269\u5b89\u5168\u6027\u5e76\u901a\u8fc7LCAR-B38M CAR-T\u7ec6\u80de\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\uff08LEGEND-2\u7814\u7a76\uff09\u7684\u6570\u636e\u6765\u786e\u8ba42\u671f\u63a8\u8350\u5242\u91cf\uff0c 2\u671f\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc4\u4f30\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u7684\u7597\u6548\uff0c\u4ee5\u603b\u7f13\u89e3\u7387\u4e3a\u4e3b\u8981\u7ec8\u70b9[2]\u3002<\/span><\/p>\n

\u5173\u4e8eCARTITUDE-4<\/p>\n

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\u66f4\u591a\u4fe1\u606f\u8bf7\u8bbf\u95ee\uff1awww.legendbiotech.cn<\/a><\/p>\n

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*\u00a0\u672c\u65b0\u95fb\u7a3f\u4e3a\u4e2d\u6587\u7ffb\u8bd1\u7248\uff0c\u5982\u4e2d\u82f1\u6587\u7248\u672c\u6709\u4efb\u4f55\u4e0d\u4e00\u81f4\u7684\u5730\u65b9\uff0c\u5e94\u4ee5\u5b98\u7f51\u53d1\u5e03\u7684\u82f1\u6587\u539f\u7a3f\uff08https:\/\/investors.legendbiotech.com\/press-releases\/<\/a>\uff09\u4e3a\u51c6\u3002<\/p>\n

\u53c2\u8003\u6765\u6e90:<\/p>\n

\n

[1] CARVYKTI\u2122 Prescribing Information. Horsham, PA: Janssen Biotech, Inc.<\/span><\/p>\n

[2] ClinicalTrials.gov. A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-Cell Maturation Antigen (BCMA) in Participants With Relapsed or Refractory Multiple Myeloma (CARTITUDE-1). Available at: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03548207<\/a> Accessed October 2022.<\/span><\/p>\n

[3] ClinicalTrials.Gov. A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma (CARTITUDE-4). https:\/\/www.clinicaltrials.gov\/study\/NCT04181827<\/a>. Accessed March 2024.<\/span><\/p>\n

[4] American Cancer Society. “What is Multiple Myeloma?”. Available at: https:\/\/www.cancer.org\/cancer\/types\/multiple-myeloma\/about\/what-is-multiple-myeloma.html<\/a>. Accessed March 2024.<\/span><\/p>\n

[5] American Cancer Society. “Key Statistics About Multiple Myeloma.” Available at: https:\/\/www.cancer.org\/cancer\/types\/multiple-myeloma\/about\/key-statistics.html<\/a>. Accessed March 2024<\/span><\/p>\n

[6] American Cancer Society. Multiple myeloma: early detection, diagnosis, and staging. Available at: https:\/\/www.cancer.org\/content\/dam\/CRC\/PDF\/Public\/8740.00.pdf<\/a>. Accessed March 2023.<\/span><\/p>\n<\/div>\n

\u00a0<\/p>\n

\u5a92\u4f53\u8054\u7edc\uff1aPR@Legendbiotech.cn<\/a>\u00a0<\/p>\n

SOURCE \u4f20\u5947\u751f\u7269<\/p>","protected":false},"excerpt":{"rendered":"

CARTITUDE-1\u7814\u7a76\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff0c\u91cd\u70b9\u5c55\u793a\u7ecf\u591a\u7ebf\u6cbb\u7597\u7684\u9aa8\u9ad3\u7624\u60a3\u8005\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u8d85\u8fc75\u5e74\u7684\u957f\u671f\u7597\u6548\u5728ASCO\u516c\u5e03\u7684CARTITUDE-4\u7814\u7a76\u65b0\u6570\u636e\u8868\u660e\uff0c\u5728\u5173\u952e\u4e9a\u7ec4\u5206\u6790\u4e2d\uff0cCARVYKTI\u00ae\u76f8\u8f83\u6807\u51c6\u6cbb\u7597\u65b9\u6848\uff08SOC\uff09\u80fd\u663e\u8457\u6539\u5584\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\u6b63\u5728\u8fdb\u884c\u7684\u6cbb\u7597\u80ba\u764c\u7684LB2102\u548c\u6cbb\u7597\u80c3\u98df\u7ba1\u764c\u7684LB1908 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LEGN\uff09\u5728\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u8428\u9ed8\u585e\u7279\u5ba3\u5e03\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u548c2025\u5e74\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684CARVYKTI\u00ae\uff08\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff0ccilta-cel\uff09\u6700\u65b0\u7814\u7a76\u6570\u636e\u3002\u6b64\u5916\uff0c\u4f20\u5947\u751f\u7269\u5728\u5b9e\u4f53\u7624\u9886\u57df\u7684\u4e24\u9879I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u2014\u2014LB2102\uff08\u7528\u4e8e\u6cbb\u7597\u80ba\u764c\uff09\u548cLB1908\uff08\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\uff09\u7684\u521d\u6b65\u7ed3\u679c\u4e5f\u5c06\u5728ASCO\u4f1a\u8bae\u7684\u58c1\u62a5\u5c55\u793a\u73af\u8282\u4e2d\u4eae\u76f8\u3002 \u4f20\u5947\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u9ec4\u9896\u535a\u58eb\u8868\u793a\uff1a “\u6211\u4eec\u5f88\u9ad8\u5174\u5728ASCO\u548cEHA\u4e0a\u5c55\u793a\u7684\u6700\u65b0\u6570\u636e\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86CARVYKTI\u00ae\u5728\u591a\u53d1\u6027\u9aa8\u9ad3\u7624CAR-T\u6cbb\u7597\u9886\u57df\u7684\u5e02\u573a\u9886\u5148\u5730\u4f4d\u3002\u8fc4\u4eca\u5df2\u6cbb\u7597\u8d85\u8fc76500\u4f8b\u60a3\u8005\uff0c\u5176\u65e5\u76ca\u663e\u8457\u7684\u4e34\u5e8a\u6548\u679c\u663e\u800c\u6613\u89c1\u3002\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u975e\u5e38\u671f\u5f85\u901a\u8fc7\u80ba\u764c\u548c\u80c3\u764c\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u6765\u5c55\u73b0\u516c\u53f8\u66f4\u5e7f\u6cdb\u7684\u7814\u53d1\u7ba1\u7ebf\u8fdb\u5c55\u2014\u2014\u6807\u5fd7\u7740\u6211\u4eec\u5728\u62d3\u5c55\u7ec6\u80de\u7597\u6cd5\u65b0\u7586\u754c\u8fc8\u51fa\u4e86\u91cd\u8981\u4e00\u6b65\u3002” CARVYKTI\u00ae\u6570\u636e \u6765\u81eaCARTITUDE-1\u7814\u7a76\u7684\u957f\u671f\u968f\u8bbf\u6570\u636e\u5c06\u5728ASCO\u5927\u4f1a\u4e0a\u9996\u6b21\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\uff0c\u5e76\u968f\u540e\u5728EHA\u5927\u4f1a\u4e0a\u518d\u6b21\u8fdb\u884c\u53e3\u5934\u62a5\u544a\u3002\u8be5\u7814\u7a76\u8bc4\u4f30\u4e86CARVYKTI\u00ae\u5728\u7ecf\u91cd\u5ea6\u9884\u5904\u7406\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u4e2d\u7684\u7597\u6548\u3002\u8fd9\u4e9b\u60a3\u8005\u65e2\u5f80\u7684\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e0d\u8db36\u4e2a\u6708\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u7ea6\u4e3a1\u5e74\u3002\u672c\u6b21\u62a5\u544a\u5c06\u5c55\u793a\u4e2d\u4f4d\u968f\u8bbf60.3\u4e2a\u6708\u7684\u5173\u952e\u6570\u636e\uff0c\u5305\u62ec\u603b\u751f\u5b58\u671f\u3001\u8d85\u8fc75\u5e74\u65e0\u8fdb\u5c55\u751f\u5b58\u7684\u7ed3\u679c\u548c\u5b89\u5168\u6027\u6570\u636e\u3002\u5728\u7814\u7a76\u4e2d\uff0c\u90a3\u4e9b\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u7684\u60a3\u8005\u5728\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\uff0c\u672a\u518d\u63a5\u53d7\u5176\u4ed6\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6cbb\u7597\u3002 CARTITUDE-4\u7814\u7a76\u7684\u610f\u5411\u6027\u6cbb\u7597\uff08ITT\uff09\u4e9a\u7ec4\u5206\u6790\u6570\u636e\u5c06\u5728ASCO\u5e74\u4f1a\u4e0a\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793a\u3002\u8fd9\u4e9b\u4e9a\u7ec4\u5305\u62ec\u5177\u6709\u9ad8\u5371\u7ec6\u80de\u9057\u4f20\u5b66\u7279\u5f81\u7684\u60a3\u8005\u4ee5\u53ca\u4f34\u9ad3\u5916\u75c5\u53d8\uff08EMD\uff09\u5e76\u63a5\u53d7\u8fc7\u4e00\u7ebf\u6cbb\u7597\u7684\u60a3\u8005\u3002\u8be5\u6570\u636e\u6301\u7eed\u652f\u6301\u4e86CARVYKTI\u00ae\u5728\u5404\u4e2a\u4e9a\u7ec4\u4e2d\u53ca\u6700\u65e9\u5728\u9996\u6b21\u590d\u53d1\u540e\u5177\u6709\u79ef\u6781\u7684\u83b7\u76ca-\u98ce\u9669\u6bd4\u3002 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ASCO\u5e74\u4f1a\u58c1\u62a5\u73af\u8282\u5c06\u5c55\u793a\u4e24\u9879\u6b63\u5728\u8fdb\u884c\u4e2d\u7684I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u7684\u521d\u6b65\u7ed3\u679c\uff1a\u5206\u522b\u4e3a\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u548c\u5927\u7ec6\u80de\u795e\u7ecf\u5185\u5206\u6ccc\u764c\uff08LCNEC\uff09\u7684dnTGF\u03b2RII\u88c5\u7532\u9776\u5411DLL3\u81ea\u4f53CAR-T\u7ec6\u80de\u7597\u6cd5LB2102\uff0c\u4ee5\u53ca\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u98df\u7ba1\u817a\u764c\u7684\u9776\u5411Claudin 18.2\u81ea\u4f53CAR-T\u7597\u6cd5LB1908\u3002 \u6b63\u5728\u8fdb\u884c\u7684LB2102 I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u6570\u636e\u5df2\u4e8e5\u670816\u65e5\u5728\u7b2c28\u5c4a\u7f8e\u56fd\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ASGCT\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u4e86\u53e3\u5934\u62a5\u544a\u3002 2023\u5e7411\u6708\uff0c\u6211\u4eec\u4e0e\u8bfa\u534e\u5236\u836f\uff08Novartis Pharma AG\uff09\u5c31\u5305\u62ecLB2102\u5728\u5185\u7684\u7279\u5b9a\u9776\u5411DLL3\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u8fbe\u6210\u4e86\u72ec\u5bb6\u5168\u7403\u8bb8\u53ef\u534f\u8bae\u3002 \u6839\u636e\u8bb8\u53ef\u534f\u8bae\uff0c\u6211\u4eec\u5c06\u5728\u7f8e\u56fd\u8fdb\u884cLB2102\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bfa\u534e\u8d1f\u8d23\u8bb8\u53ef\u4ea7\u54c1\u7684\u6240\u6709\u5176\u4ed6\u5f00\u53d1\u3002 \u00a0 2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u62a5\u544a\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f62025\u5e745\u670830\u65e5-6\u67083\u65e5\uff09 1\u3001\u6458\u8981\u7f16\u53f7\uff1a#7507 \u53e3\u5934\u62a5\u544a \u6458\u8981\u6807\u9898\uff1aLong-term (\u22655 year) remission and survival after treatment with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 patients (pts) with relapsed\/refractory multiple myeloma (RRMM)\u00a0CARTITUDE-1\u7814\u7a76\u4e2d\u63a5\u53d7\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u6cbb\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08RRMM\uff09\u60a3\u8005\u7684\u957f\u671f\uff08\u22655\u5e74\uff09\u7f13\u89e3\u4e0e\u751f\u5b58\u60c5\u51b5 \u4f1a\u8bae\u4fe1\u606f\uff1a\u4e3b\u9898\uff1a\u6076\u6027\u8840\u6db2\u80bf\u7624\u2014\u6d46\u7ec6\u80de\u75c5\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u67083\u65e5\u4e0a\u534811:57-\u4e0b\u534812:09\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09\u5730\u70b9\uff1aS100bc 2\u3001\u6458\u8981\u7f16\u53f7\uff1a#7539 \u58c1\u62a5\u5c55\u793a \u6458\u8981\u6807\u9898\uff1aCiltacabtagene autoleucel (cilta-cel) vs standard […]<\/p>\n","protected":false},"author":0,"featured_media":11484,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-11483","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\n\u7cbe\u5f69\u9884\u544a | \u4f20\u5947\u751f\u7269\u5c06\u57282025ASCO\u3001EHA\u548cASGCT\u4e0a\u516c\u5e03\u80bf\u7624\u548c\u8840\u6db2\u6cbb\u7597\u9886\u57df\u6700\u65b0\u8fdb\u5c55 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u7cbe\u5f69\u9884\u544a-\u4f20\u5947\u751f\u7269\u5c06\u57282025asco\u3001eha\u548casgct\u4e0a\u516c\u5e03\u80bf\u7624\u548c\u8840\u6db2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u7cbe\u5f69\u9884\u544a | \u4f20\u5947\u751f\u7269\u5c06\u57282025ASCO\u3001EHA\u548cASGCT\u4e0a\u516c\u5e03\u80bf\u7624\u548c\u8840\u6db2\u6cbb\u7597\u9886\u57df\u6700\u65b0\u8fdb\u5c55 - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"CARTITUDE-1\u7814\u7a76\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff0c\u91cd\u70b9\u5c55\u793a\u7ecf\u591a\u7ebf\u6cbb\u7597\u7684\u9aa8\u9ad3\u7624\u60a3\u8005\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u8d85\u8fc75\u5e74\u7684\u957f\u671f\u7597\u6548\u5728ASCO\u516c\u5e03\u7684CARTITUDE-4\u7814\u7a76\u65b0\u6570\u636e\u8868\u660e\uff0c\u5728\u5173\u952e\u4e9a\u7ec4\u5206\u6790\u4e2d\uff0cCARVYKTI\u00ae\u76f8\u8f83\u6807\u51c6\u6cbb\u7597\u65b9\u6848\uff08SOC\uff09\u80fd\u663e\u8457\u6539\u5584\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\u6b63\u5728\u8fdb\u884c\u7684\u6cbb\u7597\u80ba\u764c\u7684LB2102\u548c\u6cbb\u7597\u80c3\u98df\u7ba1\u764c\u7684LB1908 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LEGN\uff09\u5728\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u8428\u9ed8\u585e\u7279\u5ba3\u5e03\u5c06\u57282025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u548c2025\u5e74\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684CARVYKTI\u00ae\uff08\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff0ccilta-cel\uff09\u6700\u65b0\u7814\u7a76\u6570\u636e\u3002\u6b64\u5916\uff0c\u4f20\u5947\u751f\u7269\u5728\u5b9e\u4f53\u7624\u9886\u57df\u7684\u4e24\u9879I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u2014\u2014LB2102\uff08\u7528\u4e8e\u6cbb\u7597\u80ba\u764c\uff09\u548cLB1908\uff08\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\uff09\u7684\u521d\u6b65\u7ed3\u679c\u4e5f\u5c06\u5728ASCO\u4f1a\u8bae\u7684\u58c1\u62a5\u5c55\u793a\u73af\u8282\u4e2d\u4eae\u76f8\u3002 \u4f20\u5947\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u9ec4\u9896\u535a\u58eb\u8868\u793a\uff1a “\u6211\u4eec\u5f88\u9ad8\u5174\u5728ASCO\u548cEHA\u4e0a\u5c55\u793a\u7684\u6700\u65b0\u6570\u636e\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86CARVYKTI\u00ae\u5728\u591a\u53d1\u6027\u9aa8\u9ad3\u7624CAR-T\u6cbb\u7597\u9886\u57df\u7684\u5e02\u573a\u9886\u5148\u5730\u4f4d\u3002\u8fc4\u4eca\u5df2\u6cbb\u7597\u8d85\u8fc76500\u4f8b\u60a3\u8005\uff0c\u5176\u65e5\u76ca\u663e\u8457\u7684\u4e34\u5e8a\u6548\u679c\u663e\u800c\u6613\u89c1\u3002\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u975e\u5e38\u671f\u5f85\u901a\u8fc7\u80ba\u764c\u548c\u80c3\u764c\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u6765\u5c55\u73b0\u516c\u53f8\u66f4\u5e7f\u6cdb\u7684\u7814\u53d1\u7ba1\u7ebf\u8fdb\u5c55\u2014\u2014\u6807\u5fd7\u7740\u6211\u4eec\u5728\u62d3\u5c55\u7ec6\u80de\u7597\u6cd5\u65b0\u7586\u754c\u8fc8\u51fa\u4e86\u91cd\u8981\u4e00\u6b65\u3002” CARVYKTI\u00ae\u6570\u636e \u6765\u81eaCARTITUDE-1\u7814\u7a76\u7684\u957f\u671f\u968f\u8bbf\u6570\u636e\u5c06\u5728ASCO\u5927\u4f1a\u4e0a\u9996\u6b21\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\uff0c\u5e76\u968f\u540e\u5728EHA\u5927\u4f1a\u4e0a\u518d\u6b21\u8fdb\u884c\u53e3\u5934\u62a5\u544a\u3002\u8be5\u7814\u7a76\u8bc4\u4f30\u4e86CARVYKTI\u00ae\u5728\u7ecf\u91cd\u5ea6\u9884\u5904\u7406\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u60a3\u8005\u4e2d\u7684\u7597\u6548\u3002\u8fd9\u4e9b\u60a3\u8005\u65e2\u5f80\u7684\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e0d\u8db36\u4e2a\u6708\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u7ea6\u4e3a1\u5e74\u3002\u672c\u6b21\u62a5\u544a\u5c06\u5c55\u793a\u4e2d\u4f4d\u968f\u8bbf60.3\u4e2a\u6708\u7684\u5173\u952e\u6570\u636e\uff0c\u5305\u62ec\u603b\u751f\u5b58\u671f\u3001\u8d85\u8fc75\u5e74\u65e0\u8fdb\u5c55\u751f\u5b58\u7684\u7ed3\u679c\u548c\u5b89\u5168\u6027\u6570\u636e\u3002\u5728\u7814\u7a76\u4e2d\uff0c\u90a3\u4e9b\u5b58\u6d3b\u4e14\u65e0\u8fdb\u5c55\u7684\u60a3\u8005\u5728\u63a5\u53d7\u5355\u6b21CARVYKTI\u00ae\u8f93\u6ce8\u540e\uff0c\u672a\u518d\u63a5\u53d7\u5176\u4ed6\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u6cbb\u7597\u3002 CARTITUDE-4\u7814\u7a76\u7684\u610f\u5411\u6027\u6cbb\u7597\uff08ITT\uff09\u4e9a\u7ec4\u5206\u6790\u6570\u636e\u5c06\u5728ASCO\u5e74\u4f1a\u4e0a\u4ee5\u58c1\u62a5\u5f62\u5f0f\u5c55\u793a\u3002\u8fd9\u4e9b\u4e9a\u7ec4\u5305\u62ec\u5177\u6709\u9ad8\u5371\u7ec6\u80de\u9057\u4f20\u5b66\u7279\u5f81\u7684\u60a3\u8005\u4ee5\u53ca\u4f34\u9ad3\u5916\u75c5\u53d8\uff08EMD\uff09\u5e76\u63a5\u53d7\u8fc7\u4e00\u7ebf\u6cbb\u7597\u7684\u60a3\u8005\u3002\u8be5\u6570\u636e\u6301\u7eed\u652f\u6301\u4e86CARVYKTI\u00ae\u5728\u5404\u4e2a\u4e9a\u7ec4\u4e2d\u53ca\u6700\u65e9\u5728\u9996\u6b21\u590d\u53d1\u540e\u5177\u6709\u79ef\u6781\u7684\u83b7\u76ca-\u98ce\u9669\u6bd4\u3002 EHA\u5e74\u4f1a\u4e0a\u5c06\u4ee5\u58c1\u62a5\u5f62\u5f0f\u53d1\u8868\u4e00\u9879\u751f\u7269\u6807\u5fd7\u7269\u5206\u6790\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u63a2\u8ba8\u4e86CARVYKTI\u00ae\u6cbb\u7597\u540e\u51fa\u73b0\u7684\u8fd0\u52a8\u53ca\u795e\u7ecf\u8ba4\u77e5\u4e0d\u826f\u4e8b\u4ef6\uff08MNT\uff09\u548c\u9885\u795e\u7ecf\u9ebb\u75f9\uff08CNP\uff09\u4e0e\u7279\u5b9a\u751f\u7269\u6807\u5fd7\u7269\u7684\u76f8\u5173\u6027\u3002 \u5b9e\u4f53\u7624\u7ba1\u7ebf ASCO\u5e74\u4f1a\u58c1\u62a5\u73af\u8282\u5c06\u5c55\u793a\u4e24\u9879\u6b63\u5728\u8fdb\u884c\u4e2d\u7684I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u7684\u521d\u6b65\u7ed3\u679c\uff1a\u5206\u522b\u4e3a\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u548c\u5927\u7ec6\u80de\u795e\u7ecf\u5185\u5206\u6ccc\u764c\uff08LCNEC\uff09\u7684dnTGF\u03b2RII\u88c5\u7532\u9776\u5411DLL3\u81ea\u4f53CAR-T\u7ec6\u80de\u7597\u6cd5LB2102\uff0c\u4ee5\u53ca\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u98df\u7ba1\u817a\u764c\u7684\u9776\u5411Claudin 18.2\u81ea\u4f53CAR-T\u7597\u6cd5LB1908\u3002 \u6b63\u5728\u8fdb\u884c\u7684LB2102 I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u6570\u636e\u5df2\u4e8e5\u670816\u65e5\u5728\u7b2c28\u5c4a\u7f8e\u56fd\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ASGCT\uff09\u5e74\u4f1a\u4e0a\u8fdb\u884c\u4e86\u53e3\u5934\u62a5\u544a\u3002 2023\u5e7411\u6708\uff0c\u6211\u4eec\u4e0e\u8bfa\u534e\u5236\u836f\uff08Novartis Pharma AG\uff09\u5c31\u5305\u62ecLB2102\u5728\u5185\u7684\u7279\u5b9a\u9776\u5411DLL3\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u8fbe\u6210\u4e86\u72ec\u5bb6\u5168\u7403\u8bb8\u53ef\u534f\u8bae\u3002 \u6839\u636e\u8bb8\u53ef\u534f\u8bae\uff0c\u6211\u4eec\u5c06\u5728\u7f8e\u56fd\u8fdb\u884cLB2102\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bfa\u534e\u8d1f\u8d23\u8bb8\u53ef\u4ea7\u54c1\u7684\u6240\u6709\u5176\u4ed6\u5f00\u53d1\u3002 \u00a0 2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u62a5\u544a\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f62025\u5e745\u670830\u65e5-6\u67083\u65e5\uff09 1\u3001\u6458\u8981\u7f16\u53f7\uff1a#7507 \u53e3\u5934\u62a5\u544a \u6458\u8981\u6807\u9898\uff1aLong-term (\u22655 year) remission and survival after treatment with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 patients (pts) with relapsed\/refractory multiple myeloma (RRMM)\u00a0CARTITUDE-1\u7814\u7a76\u4e2d\u63a5\u53d7\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08cilta-cel\uff09\u6cbb\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08RRMM\uff09\u60a3\u8005\u7684\u957f\u671f\uff08\u22655\u5e74\uff09\u7f13\u89e3\u4e0e\u751f\u5b58\u60c5\u51b5 \u4f1a\u8bae\u4fe1\u606f\uff1a\u4e3b\u9898\uff1a\u6076\u6027\u8840\u6db2\u80bf\u7624\u2014\u6d46\u7ec6\u80de\u75c5\u65e5\u671f\/\u65f6\u95f4\uff1a2025\u5e746\u67083\u65e5\u4e0a\u534811:57-\u4e0b\u534812:09\uff08\u5317\u7f8e\u4e2d\u90e8\u590f\u4ee4\u65f6\uff09\u5730\u70b9\uff1aS100bc 2\u3001\u6458\u8981\u7f16\u53f7\uff1a#7539 \u58c1\u62a5\u5c55\u793a \u6458\u8981\u6807\u9898\uff1aCiltacabtagene autoleucel (cilta-cel) vs standard […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u7cbe\u5f69\u9884\u544a-\u4f20\u5947\u751f\u7269\u5c06\u57282025asco\u3001eha\u548casgct\u4e0a\u516c\u5e03\u80bf\u7624\u548c\u8840\u6db2\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-23T00:00:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/Logo-ffoGpn.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"144\" \/>\n\t<meta property=\"og:image:height\" content=\"63\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" 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