{"id":11513,"date":"2025-05-23T08:04:00","date_gmt":"2025-05-23T08:04:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/"},"modified":"2025-05-23T08:04:00","modified_gmt":"2025-05-23T08:04:00","slug":"%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/","title":{"rendered":"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf"},"content":{"rendered":"<p><span class=\"xn-money\">DZD8586<\/span>\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u548c\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027<span class=\"xn-money\">DZD6008<\/span>\uff0c\u65b0\u4e00\u4ee3\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u5355\u836f\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u4e2d\uff0c\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u4e14\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3001\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027<\/p>\n<p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2025\u5e745\u670823\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; 2025\u5e745\u670823\u65e5\uff0c\u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u4e24\u6b3e\u6e90\u5934\u521b\u65b0\u4ea7\u54c1DZD8586\u548cDZD6008\u5c06\u4e8e2025\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\uff0c\u5206\u522b\u5c55\u793a\u5728B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u9886\u57df\u76843\u9879\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\uff0c\u5f70\u663e\u8fea\u54f2\u533b\u836f\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u5dee\u5f02\u5316\u7ade\u4e89\u4e2d\u7684\u65b0\u4f18\u52bf\u3002\u5176\u4e2d\uff0c\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u7684\u6c47\u603b\u5206\u6790\u6210\u679c\u5c06\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<p>\n                        <a href=\"https:\/\/mma.prnewswire.com\/media\/2694815\/1.html\" target=\"_blank\" rel=\"noopener\"><\/a><\/p>\n<p>                        \n                <\/p>\n<\/div>\n<p class=\"prntac\"><span class=\"xn-money\">DZD8586<\/span>\uff1a\u6709\u671b\u4e3aB-NHL\u60a3\u8005\u5e26\u6765\u5168\u65b0\u6cbb\u7597\u9009\u62e9<\/p>\n<p>DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u7684\u4e00\u9879\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u6c47\u603b\u5206\u6790\uff0c\u5c06\u5728\u672c\u6b21ASCO\u5927\u4f1a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff08\u6458\u8981\u7f16\u53f7\uff1a7010\uff09\u3002\u622a\u81f32025\u5e744\u67084\u65e5\uff0c\u7814\u7a76\u5171\u5165\u7ec451\u4f8b\u590d\u53d1\/\u96be\u6cbb\uff08r\/r\uff09CLL\/SLL\u60a3\u8005\u63a5\u53d7DZD8586\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u572850mg\u5242\u91cf\u4e0b\uff0cDZD8586\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\uff0c\u4e14\u5b89\u5168\u6027\u53ef\u63a7\uff1a<\/p>\n<p>\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u9ad8\u8fbe84.2%\uff0c\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242\u3001Bcl-2\u6291\u5236\u5242\u6216BTK\u964d\u89e3\u5242\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u5206\u522b\u89c2\u5bdf\u523082.4%\u300183.3%\u548c50%\u7684\u80bf\u7624\u7f13\u89e3\u5728\u643a\u5e26\u7ecf\u5178BTK\u8010\u836f\u7a81\u53d8\uff08C481X\uff09\uff0c\u4ee5\u53ca\u5305\u62ecBTK\u6fc0\u9176\u5931\u6d3b\u7a81\u53d8\u7b49\u5176\u4ed6BTK\u7a81\u53d8\u7684\u60a3\u8005\u4e2d\uff0c\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u89c2\u5bdf\u5230\u6301\u4e45\u7f13\u89e3\uff0c\u9884\u8ba19\u4e2a\u6708\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u7387\u4e3a83.3%\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u5c1a\u672a\u6210\u719f\uff0c78.9%\u7684\u60a3\u8005\u4ecd\u5728\u6301\u7eed\u63a5\u53d7DZD8586\u6cbb\u7597<\/p>\n<p>\u4e3b\u8981\u7814\u7a76\u8005\u3001\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\u674e\u5efa\u52c7\u6559\u6388\u8868\u793a\uff1a&#8221;DZD8586\u901a\u8fc7LYN\/BTK\u975e\u5171\u4ef7\u53cc\u9776\u70b9\u963b\u65ad\u4f18\u52bf\uff0c\u80fd\u591f\u5728\u590d\u53d1\/\u96be\u6cbb\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r CLL\/SLL\uff09\u60a3\u8005\u4e2d\u53d6\u5f97\u7a81\u7834\uff0c\u4ece\u7814\u7a76\u7ed3\u679c\u770b\u5176\u5177\u5907\u653b\u514b\u591a\u91cd\u8010\u836f\uff0c\u89c4\u907f\u4f20\u7edfBTK\u6291\u5236\u5242\u56e0\u9776\u70b9\u8017\u7aed\u6216\u65c1\u8def\u6fc0\u6d3b\u5bfc\u81f4\u7684\u8010\u836f\uff0c\u4e3a\u6cbb\u7597\u63d0\u4f9b\u65b0\u673a\u9047\u548c\u65b0\u7b56\u7565\uff0c\u671f\u5f85\u540e\u7eed\u7814\u7a76\u4e2d\u80fd\u6709\u66f4\u591a\u597d\u7684\u7ed3\u679c\u5448\u73b0\u3002&#8221;<\/p>\n<p>\u6b64\u5916\uff0cDZD8586\u53e6\u4e00\u9879\u5c06\u5728ASCO\u5927\u4f1a\u5c55\u793a\u7684\u662f\u5176\u5355\u836f\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff08\u6458\u8981\u7f16\u53f7\uff1ae19050\uff09\u3002\u5165\u7ec4\u7684r\/r DLBCL\u60a3\u8005\u65e2\u5f80\u63a5\u53d7\u8fc71\u81f34\u7ebf\u7684\u7cfb\u7edf\u6027\u6cbb\u7597\uff0c\u4e14\u6cbb\u7597\u65b9\u6848\u5747\u5305\u542b\u4ee5\u84bd\u73af\u7c7b\u836f\u7269\u8054\u5408\u6297CD20\u5355\u6297\u4e3a\u57fa\u7840\u7684\u5316\u7597\u514d\u75ab\u6cbb\u7597\u3002\u7814\u7a76\u6570\u636e\u663e\u793a\uff1a\u572850 mg\u548c75 mg\u5242\u91cf\u4e0b\uff0cDZD8586\u9488\u5bf9r\/r DLBCL\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e14\u5728GCB\u4e9a\u578b\u53ca\u975eGCB\u4e9a\u578b\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u3002\u8be5\u7814\u7a76\u7684\u6700\u65b0\u6570\u636e\u5c06\u57282025\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u3002<\/p>\n<p>\u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8840\u6db2\u75c5\u533b\u9662\u90b1\u5f55\u8d35\u6559\u6388\u8868\u793a\uff1a&#8221;\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u591a\u7ebf\u6cbb\u7597\u540e\u7684\u8010\u836f\u95ee\u9898\u4e00\u76f4\u56f0\u6270\u4e34\u5e8a\u8bca\u7597\uff0cDZD8586\u4f5c\u4e3a\u53cc\u9776\u70b9\u975e\u5171\u4ef7\u6291\u5236\u5242\uff0c\u5728GCB\/\u975eGCB\u4e9a\u578b\u4e2d\u5747\u6709\u6548\uff0c\u540c\u65f6\u80fd\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u5177\u5907\u4e2d\u67a2\u6cbb\u7597\u6f5c\u529b\uff0c\u6216\u53ef\u89e3\u51b3\u4f34\u4e2d\u67a2\u4fb5\u72af\u60a3\u8005\u7684\u6cbb\u7597\u75db\u70b9\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u6765\u53ef\u671f\u3002&#8221;<\/p>\n<p class=\"prntac\"><span class=\"xn-money\">DZD6008<\/span>\uff1a\u6709\u671b\u586b\u8865NSCLC\u9886\u57df\u672a\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42<\/p>\n<p>\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9886\u57df\uff0cDZD6008\u5355\u836f\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u4e34\u5e8a\u524d\u548c\u2160\/\u2161\u671f\u9996\u6b21\u4eba\u4f53\u7814\u7a76\uff08TIAN-SHAN2\uff09\u7684\u65e9\u671f\u4e34\u5e8a\u79ef\u6781\u6570\u636e\uff0c\u4e5f\u5c06\u4eae\u76f8ASCO\u5927\u4f1a\uff08\u6458\u8981\u7f16\u53f7\uff1a8616\uff09\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0cDZD6008\u5bf9\u4e8eEGFR\u654f\u611f\u7a81\u53d8\uff08L858R\/del19\uff09\u3001\u8010\u836f\u53cc\u7a81\u53d8\uff08T790M\u548cL858R\/del19\uff09\u4ee5\u53ca\u4e09\u91cd\u7a81\u53d8\uff08C797X\u3001T790M\u548cL858R\/del19\uff09\u5177\u6709\u5f3a\u6548\u4e14\u76f8\u4f3c\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5bf9\u91ce\u751f\u578bEGFR\u5177\u6709\u8d85\u8fc750\u500d\u7684\u9ad8\u9009\u62e9\u6027\u3002<\/p>\n<p>TIAN-SHAN2\uff0c\u4e00\u9879\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u622a\u81f32025\u5e743\u670831\u65e5\uff0cDZD6008\u5355\u836f\u5728\u5165\u7ec4\u768412\u4f8b\u65e2\u5f80\u7ecf\u8fc7\u5145\u5206\u6cbb\u7597\uff08\u4e2d\u4f4d4.5\u7ebf\uff0c\u8303\u56f42-8\u7ebf\uff09\u3001\u643a\u5e26\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u665a\u671fNSCLC\u60a3\u8005\u4e2d\uff0c\u8868\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u5e76\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u63a5\u53d7DZD6008\u6cbb\u7597\u540e\uff0c10\u4f8b\u60a3\u8005\uff0883.3%\uff09\u663e\u793a\u9776\u75c5\u7076\u80bf\u7624\u7f29\u5c0f\u3002\u5728\u8d77\u59cb\u5242\u91cf20 mg\u53ca\u66f4\u9ad8\u5242\u91cf\u7ec4\uff0c\u643a\u5e26\u591a\u79cd\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u60a3\u8005\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u6b64\u5916\uff0c\u4e0e\u4e34\u5e8a\u524d\u6570\u636e\u4e00\u81f4\uff0cDZD6008\u5728\u60a3\u8005\u4f53\u5185\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\uff0c\u8111\u810a\u6db2\u4e2d\u836f\u7269\u6d53\u5ea6\u4e0e\u6e38\u79bb\u8840\u6d46\u836f\u7269\u6d53\u5ea6\u6bd4\u503c\u8d85\u8fc71\uff0c\u5728\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u4e2d\u4e5f\u8bc1\u5b9e\u4e86\u5176\u6301\u4e45\u7684\u7597\u6548\u53cd\u5e94\u3002<\/p>\n<p>\u4e3b\u8981\u7814\u7a76\u8005\u3001\u5317\u4eac\u534f\u548c\u533b\u9662\u738b\u5b5f\u662d\u6559\u6388\u8868\u793a\uff1a&#8221;DZD6008\u4f5c\u4e3a\u4e00\u6b3e\u5168\u65b0\u3001\u5f3a\u6548\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u00a0\u5177\u5907\u5e7f\u8c31\u6291\u5236\u80fd\u529b\u548c\u5353\u8d8a\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\u3002\u6b64\u6b21ASCO\u5927\u4f1a\u516c\u5e03\u7684\u2160\/\u2161\u671f\u7814\u7a76\u6570\u636e\u63d0\u793a\u5176\u9488\u5bf9EGFR TKI\u8010\u836f\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5177\u6709\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\u548c\u8010\u53d7\u6027\uff0c\u7279\u522b\u662f\u5176\u6cbb\u7597\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u6301\u4e45\u7684\u7f13\u89e3\u7597\u6548\u4ee4\u4eba\u9f13\u821e\u3002\u76ee\u524d\uff0cTIAN-SHAN2\u7814\u7a76\u6b63\u6301\u7eed\u63a8\u8fdb\uff0c\u65e8\u5728\u8fdb\u4e00\u6b65\u9a8c\u8bc1DZD6008\u5728\u66f4\u5e7f\u6cdb\u4eba\u7fa4\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff0c\u8fd9\u9879\u7814\u7a76\u6709\u671b\u4e3a\u665a\u671f\u80ba\u764c\u60a3\u8005\u6784\u5efa\u66f4\u5b8c\u6574\u7684\u8010\u836f\u540e\u6cbb\u7597\u751f\u6001\u94fe\uff0c\u63a8\u52a8\u80ba\u764c\u7cbe\u51c6\u6cbb\u7597\u8fdb\u5165\u65b0\u9636\u6bb5\u3002&#8221;<\/p>\n<p>\u8fea\u54f2\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5f20\u5c0f\u6797\u535a\u58eb\u8868\u793a\uff1a&#8221;\u672c\u6b21ASCO\u5927\u4f1a\u4e0a\u516c\u5e03\u7684DZD8586\u548cDZD6008\u591a\u9879\u4e34\u5e8a\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u5f70\u663e\u4e86\u8fea\u54f2\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u7684\u96be\u6cbb\u6027\u80bf\u7624\u9886\u57df\u7684\u7814\u53d1\u5b9e\u529b\u4e0e\u5168\u7403\u5dee\u5f02\u6027\u7ade\u4e89\u4f18\u52bf\u3002\u5c24\u5176\u662fDZD8586\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u60a3\u8005\u7597\u6548\u663e\u8457\uff0c\u4e3a\u6211\u4eec\u63a5\u4e0b\u6765\u63a8\u8fdbDZD8586\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u6ce8\u5165\u4e86\u5de8\u5927\u7684\u4fe1\u5fc3\u4e0e\u52a8\u529b\u3002\u672a\u6765\uff0c\u6211\u4eec\u5c06\u6301\u7eed\u52a0\u901f\u8fd9\u4e24\u6b3e\u6838\u5fc3\u4ea7\u54c1\u7684\u5168\u7403\u5f00\u53d1\u6b65\u4f10\uff0c\u671f\u5f85\u80fd\u591f\u7ed9B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7597\u65b0\u9009\u62e9\u3002&#8221;<\/p>\n<p>\u5173\u4e8e<span class=\"xn-money\">DZD8586<\/span><\/p>\n<p>DZD8586\u662f\u4e00\u6b3e\u5168\u7403\u9996\u521b\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u975e\u5171\u4ef7LYN\/BTK\u53cc\u9776\u70b9\u6291\u5236\u5242\uff0c\u5bf9\u5176\u4ed6TEC\u5bb6\u65cf\u6fc0\u9176\uff08TEC\u3001ITK\u3001TXK\u548cBMX\uff09\u5177\u6709\u9ad8\u9009\u62e9\u6027\uff0c\u53ef\u540c\u65f6\u963b\u65ad\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u4f9d\u8d56\u6027\u548c\u975e\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\uff0c\u6709\u6548\u6291\u5236\u591a\u79cdB\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u4e9a\u578b\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002<\/p>\n<p>\u5c3d\u7ba1\u73b0\u6709BTK\u6291\u5236\u5242\u5bf9\u90e8\u5206B-NHL\u4e9a\u578b\u4e34\u5e8a\u7597\u6548\u663e\u8457\uff0c\u4f46\u8010\u836f\u6027\u4e00\u76f4\u662f\u4e34\u5e8a\u4e00\u5927\u96be\u9898\u3002\u4e3b\u8981\u7531\u4e24\u79cd\u673a\u5236\u5f15\u53d1\uff1a\u4e00\u79cd\u662fC481X BTK\u7a81\u53d8\uff0c\u53e6\u4e00\u79cd\u5219\u662f\u975eBTK\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\u6fc0\u6d3b\u3002\u5f53\u524d\uff0c\u5c1a\u65e0\u836f\u7269\u80fd\u540c\u65f6\u5e94\u5bf9\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u3002\u6b64\u5916\uff0c\u867d\u7136BTK\u964d\u89e3\u5242\u5728\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\uff0c\u7a81\u53d8\u76f8\u5173\u7684\u8010\u836f\u5df2\u6709\u62a5\u9053\uff0c\u4e14\u964d\u89e3\u5242\u76f8\u5173\u7684\u6bd2\u526f\u53cd\u5e94\u53ef\u80fd\u5f71\u54cd\u4e34\u5e8a\u7684\u957f\u671f\u5e94\u7528\u3002\u65e2\u5f80\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0cDZD8586\u5177\u6709\u826f\u597d\u7684\u53e3\u670d\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6e17\u900f\u80fd\u529b\uff0c\u80fd\u5168\u9762\u963b\u65adBCR\u4fe1\u53f7\u901a\u8def\uff0c\u6cbb\u7597\u7531\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u5f15\u53d1\u7684B-NHL\uff0c\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u826f\u597d\uff0c\u5e76\u5728\u591a\u79cdB-NHL\u4e9a\u578b\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\u3002<\/p>\n<p>\u5173\u4e8e<span class=\"xn-money\">DZD6008<\/span><\/p>\n<p>DZD6008\u662f\u4e00\u6b3e\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5168\u65b0\u7684\u3001\u9ad8\u9009\u62e9\u6027\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\uff0c\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u80fd\u6709\u6548\u6291\u5236\u591a\u79cdEGFR\u7a81\u53d8\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002\u5f53\u524d\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09EGFR TKI\u8010\u836f\u673a\u5236\u672a\u660e\uff0c\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\u3002\u540c\u65f6\uff0c\u8111\u8f6c\u79fb\u662f\u5bfc\u81f4\u75be\u75c5\u8fdb\u5c55\u53ca\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c23%-30%\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5728\u521d\u6b21\u8bca\u65ad\u65f6\u5373\u5b58\u5728\u8111\u8f6c\u79fb\uff0c\u8bca\u65ad\u540e3\u5e74\u5185\u8111\u8f6c\u79fb\u7684\u98ce\u9669\u53ef\u80fd\u589e\u81f329.4%-60.3%\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u9488\u5bf9\u4e09\u4ee3EGFR TKI\u8010\u836fNSCLC\u7684\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u7684\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\uff0cDZD6008\u6709\u671b\u586b\u8865\u8be5\u9886\u57df\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002DZD6008\u5728\u5df2\u6709\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5b8c\u5168\u9a8c\u8bc1\u4e86\u8be5\u5206\u5b50\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u5728\u4e09\u4ee3EGFR TKI\u548c\u591a\u7ebf\u6cbb\u7597\u5931\u8d25\u53ca\u8111\u8f6c\u79fb\u7684\u75c5\u4eba\u4e2d\u663e\u793a\u4f18\u5f02\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/p>\n<p>\u5173\u4e8e\u8fea\u54f2\u533b\u836f<\/p>\n<p>\u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u662f\u4e00\u5bb6\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u3001\u514d\u75ab\u6027\u75be\u75c5\u9886\u57df\u521b\u65b0\u7597\u6cd5\u7684\u7814\u7a76\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u516c\u53f8\u575a\u6301\u6e90\u5934\u521b\u65b0\u7684\u7814\u53d1\u7406\u5ff5\uff0c\u4ee5\u63a8\u51fa\u5168\u7403\u9996\u521b\u836f\u7269\uff08First-in-class\uff09\u548c\u5177\u6709\u7a81\u7834\u6027\u6f5c\u529b\u7684\u6cbb\u7597\u65b9\u6cd5\u4e3a\u76ee\u6807\uff0c\u65e8\u5728\u586b\u8865\u5168\u7403\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u57fa\u4e8e\u884c\u4e1a\u9886\u5148\u7684\u8f6c\u5316\u79d1\u5b66\u548c\u65b0\u836f\u5206\u5b50\u8bbe\u8ba1\u4e0e\u7b5b\u9009\u6280\u672f\u5e73\u53f0\uff0c\u516c\u53f8\u5df2\u5efa\u7acb\u4e86\u4e03\u6b3e\u5177\u5907\u5168\u7403\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d\u4e24\u5927\u5904\u4e8e\u5168\u7403\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u9886\u5148\u4ea7\u54c1\uff0c\u5747\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u5173\u6ce8\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a\u8fea\u54f2Dizal\uff0c\u6216\u8bbf\u95ee<a href=\"https:\/\/www.dizalpharma.com\/\" target=\"_blank\" rel=\"noopener\">https:\/\/www.dizalpharma.com<\/a>\u3002<\/p>\n<p>\u524d\u77bb\u6027\u58f0\u660e<\/p>\n<p>\u672c\u65b0\u95fb\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u8fd9\u4e9b\u8868\u8ff0\u672c\u8d28\u4e0a\u5177\u6709\u76f8\u5f53\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u3002\u5728\u4f7f\u7528&#8221;\u9884\u671f&#8221;\u3001&#8221;\u76f8\u4fe1&#8221;\u3001&#8221;\u9884\u6d4b&#8221;\u3001&#8221;\u671f\u671b&#8221;\u3001&#8221;\u6253\u7b97&#8221;\u3001&#8221;\u6709\u671b&#8221;\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u65f6\uff0c\u51e1\u4e0e\u672c\u516c\u53f8\u6709\u5173\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c5e\u524d\u77bb\u6027\u8868\u8ff0\u3002<\/p>\n<p>\u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u672a\u6765\u4e8b\u52a1\u7684\u73b0\u6709\u770b\u6cd5\u3001\u5047\u8bbe\u3001\u671f\u671b\u3001\u4f30\u8ba1\u3001\u9884\u6d4b\u548c\u7406\u89e3\u3002\u8fd9\u4e9b\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u53d1\u5c55\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002<\/p>\n<p>\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u5458\u6982\u4e0d\u627f\u62c5\uff08a\uff09\u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7f51\u7ad9\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u4e49\u52a1\uff1b\u53ca\uff08b\uff09\u00a0\u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5b9e\u73b0\u6216\u53d8\u6210\u4e0d\u6b63\u786e\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8d23\u4efb\u3002<\/p>\n<p>\u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8bf7\u8054\u7cfb<br \/>\u6295\u8d44\u8005\u5173\u7cfb\uff1a<a href=\"mailto:ir@dizalpharma.com\" target=\"_blank\" rel=\"noopener\">ir@dizalpharma.com<\/a>\u00a0\u00a0<br \/>\u5546\u52a1\u5408\u4f5c\uff1a<a href=\"mailto:bd@dizalpharma.com\" target=\"_blank\" rel=\"noopener\">bd@dizalpharma.com<\/a>\u00a0 \u00a0<br \/>\u5a92\u4f53\u8054\u7edc\uff1a<a href=\"mailto:pr@dizalpharma.com\" target=\"_blank\" rel=\"noopener\">pr@dizalpharma.com<\/a>\u00a0<\/p>\n<p>SOURCE  \u8fea\u54f2\u533b\u836f<\/p>","protected":false},"excerpt":{"rendered":"<p>DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u548c\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027DZD6008\uff0c\u65b0\u4e00\u4ee3\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u5355\u836f\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u4e2d\uff0c\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u4e14\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3001\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027 \u4e0a\u6d772025\u5e745\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 2025\u5e745\u670823\u65e5\uff0c\u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u4e24\u6b3e\u6e90\u5934\u521b\u65b0\u4ea7\u54c1DZD8586\u548cDZD6008\u5c06\u4e8e2025\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\uff0c\u5206\u522b\u5c55\u793a\u5728B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u9886\u57df\u76843\u9879\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\uff0c\u5f70\u663e\u8fea\u54f2\u533b\u836f\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u5dee\u5f02\u5316\u7ade\u4e89\u4e2d\u7684\u65b0\u4f18\u52bf\u3002\u5176\u4e2d\uff0c\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u7684\u6c47\u603b\u5206\u6790\u6210\u679c\u5c06\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u3002 DZD8586\uff1a\u6709\u671b\u4e3aB-NHL\u60a3\u8005\u5e26\u6765\u5168\u65b0\u6cbb\u7597\u9009\u62e9 DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u7684\u4e00\u9879\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u6c47\u603b\u5206\u6790\uff0c\u5c06\u5728\u672c\u6b21ASCO\u5927\u4f1a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff08\u6458\u8981\u7f16\u53f7\uff1a7010\uff09\u3002\u622a\u81f32025\u5e744\u67084\u65e5\uff0c\u7814\u7a76\u5171\u5165\u7ec451\u4f8b\u590d\u53d1\/\u96be\u6cbb\uff08r\/r\uff09CLL\/SLL\u60a3\u8005\u63a5\u53d7DZD8586\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u572850mg\u5242\u91cf\u4e0b\uff0cDZD8586\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\uff0c\u4e14\u5b89\u5168\u6027\u53ef\u63a7\uff1a \u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u9ad8\u8fbe84.2%\uff0c\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242\u3001Bcl-2\u6291\u5236\u5242\u6216BTK\u964d\u89e3\u5242\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u5206\u522b\u89c2\u5bdf\u523082.4%\u300183.3%\u548c50%\u7684\u80bf\u7624\u7f13\u89e3\u5728\u643a\u5e26\u7ecf\u5178BTK\u8010\u836f\u7a81\u53d8\uff08C481X\uff09\uff0c\u4ee5\u53ca\u5305\u62ecBTK\u6fc0\u9176\u5931\u6d3b\u7a81\u53d8\u7b49\u5176\u4ed6BTK\u7a81\u53d8\u7684\u60a3\u8005\u4e2d\uff0c\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u89c2\u5bdf\u5230\u6301\u4e45\u7f13\u89e3\uff0c\u9884\u8ba19\u4e2a\u6708\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u7387\u4e3a83.3%\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u5c1a\u672a\u6210\u719f\uff0c78.9%\u7684\u60a3\u8005\u4ecd\u5728\u6301\u7eed\u63a5\u53d7DZD8586\u6cbb\u7597 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\u674e\u5efa\u52c7\u6559\u6388\u8868\u793a\uff1a&#8221;DZD8586\u901a\u8fc7LYN\/BTK\u975e\u5171\u4ef7\u53cc\u9776\u70b9\u963b\u65ad\u4f18\u52bf\uff0c\u80fd\u591f\u5728\u590d\u53d1\/\u96be\u6cbb\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r CLL\/SLL\uff09\u60a3\u8005\u4e2d\u53d6\u5f97\u7a81\u7834\uff0c\u4ece\u7814\u7a76\u7ed3\u679c\u770b\u5176\u5177\u5907\u653b\u514b\u591a\u91cd\u8010\u836f\uff0c\u89c4\u907f\u4f20\u7edfBTK\u6291\u5236\u5242\u56e0\u9776\u70b9\u8017\u7aed\u6216\u65c1\u8def\u6fc0\u6d3b\u5bfc\u81f4\u7684\u8010\u836f\uff0c\u4e3a\u6cbb\u7597\u63d0\u4f9b\u65b0\u673a\u9047\u548c\u65b0\u7b56\u7565\uff0c\u671f\u5f85\u540e\u7eed\u7814\u7a76\u4e2d\u80fd\u6709\u66f4\u591a\u597d\u7684\u7ed3\u679c\u5448\u73b0\u3002&#8221; \u6b64\u5916\uff0cDZD8586\u53e6\u4e00\u9879\u5c06\u5728ASCO\u5927\u4f1a\u5c55\u793a\u7684\u662f\u5176\u5355\u836f\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff08\u6458\u8981\u7f16\u53f7\uff1ae19050\uff09\u3002\u5165\u7ec4\u7684r\/r DLBCL\u60a3\u8005\u65e2\u5f80\u63a5\u53d7\u8fc71\u81f34\u7ebf\u7684\u7cfb\u7edf\u6027\u6cbb\u7597\uff0c\u4e14\u6cbb\u7597\u65b9\u6848\u5747\u5305\u542b\u4ee5\u84bd\u73af\u7c7b\u836f\u7269\u8054\u5408\u6297CD20\u5355\u6297\u4e3a\u57fa\u7840\u7684\u5316\u7597\u514d\u75ab\u6cbb\u7597\u3002\u7814\u7a76\u6570\u636e\u663e\u793a\uff1a\u572850 mg\u548c75 mg\u5242\u91cf\u4e0b\uff0cDZD8586\u9488\u5bf9r\/r DLBCL\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e14\u5728GCB\u4e9a\u578b\u53ca\u975eGCB\u4e9a\u578b\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u3002\u8be5\u7814\u7a76\u7684\u6700\u65b0\u6570\u636e\u5c06\u57282025\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8840\u6db2\u75c5\u533b\u9662\u90b1\u5f55\u8d35\u6559\u6388\u8868\u793a\uff1a&#8221;\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u591a\u7ebf\u6cbb\u7597\u540e\u7684\u8010\u836f\u95ee\u9898\u4e00\u76f4\u56f0\u6270\u4e34\u5e8a\u8bca\u7597\uff0cDZD8586\u4f5c\u4e3a\u53cc\u9776\u70b9\u975e\u5171\u4ef7\u6291\u5236\u5242\uff0c\u5728GCB\/\u975eGCB\u4e9a\u578b\u4e2d\u5747\u6709\u6548\uff0c\u540c\u65f6\u80fd\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u5177\u5907\u4e2d\u67a2\u6cbb\u7597\u6f5c\u529b\uff0c\u6216\u53ef\u89e3\u51b3\u4f34\u4e2d\u67a2\u4fb5\u72af\u60a3\u8005\u7684\u6cbb\u7597\u75db\u70b9\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u6765\u53ef\u671f\u3002&#8221; DZD6008\uff1a\u6709\u671b\u586b\u8865NSCLC\u9886\u57df\u672a\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42 \u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9886\u57df\uff0cDZD6008\u5355\u836f\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u4e34\u5e8a\u524d\u548c\u2160\/\u2161\u671f\u9996\u6b21\u4eba\u4f53\u7814\u7a76\uff08TIAN-SHAN2\uff09\u7684\u65e9\u671f\u4e34\u5e8a\u79ef\u6781\u6570\u636e\uff0c\u4e5f\u5c06\u4eae\u76f8ASCO\u5927\u4f1a\uff08\u6458\u8981\u7f16\u53f7\uff1a8616\uff09\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0cDZD6008\u5bf9\u4e8eEGFR\u654f\u611f\u7a81\u53d8\uff08L858R\/del19\uff09\u3001\u8010\u836f\u53cc\u7a81\u53d8\uff08T790M\u548cL858R\/del19\uff09\u4ee5\u53ca\u4e09\u91cd\u7a81\u53d8\uff08C797X\u3001T790M\u548cL858R\/del19\uff09\u5177\u6709\u5f3a\u6548\u4e14\u76f8\u4f3c\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5bf9\u91ce\u751f\u578bEGFR\u5177\u6709\u8d85\u8fc750\u500d\u7684\u9ad8\u9009\u62e9\u6027\u3002 TIAN-SHAN2\uff0c\u4e00\u9879\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u622a\u81f32025\u5e743\u670831\u65e5\uff0cDZD6008\u5355\u836f\u5728\u5165\u7ec4\u768412\u4f8b\u65e2\u5f80\u7ecf\u8fc7\u5145\u5206\u6cbb\u7597\uff08\u4e2d\u4f4d4.5\u7ebf\uff0c\u8303\u56f42-8\u7ebf\uff09\u3001\u643a\u5e26\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u665a\u671fNSCLC\u60a3\u8005\u4e2d\uff0c\u8868\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u5e76\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u63a5\u53d7DZD6008\u6cbb\u7597\u540e\uff0c10\u4f8b\u60a3\u8005\uff0883.3%\uff09\u663e\u793a\u9776\u75c5\u7076\u80bf\u7624\u7f29\u5c0f\u3002\u5728\u8d77\u59cb\u5242\u91cf20 mg\u53ca\u66f4\u9ad8\u5242\u91cf\u7ec4\uff0c\u643a\u5e26\u591a\u79cd\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u60a3\u8005\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u6b64\u5916\uff0c\u4e0e\u4e34\u5e8a\u524d\u6570\u636e\u4e00\u81f4\uff0cDZD6008\u5728\u60a3\u8005\u4f53\u5185\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\uff0c\u8111\u810a\u6db2\u4e2d\u836f\u7269\u6d53\u5ea6\u4e0e\u6e38\u79bb\u8840\u6d46\u836f\u7269\u6d53\u5ea6\u6bd4\u503c\u8d85\u8fc71\uff0c\u5728\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u4e2d\u4e5f\u8bc1\u5b9e\u4e86\u5176\u6301\u4e45\u7684\u7597\u6548\u53cd\u5e94\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u5317\u4eac\u534f\u548c\u533b\u9662\u738b\u5b5f\u662d\u6559\u6388\u8868\u793a\uff1a&#8221;DZD6008\u4f5c\u4e3a\u4e00\u6b3e\u5168\u65b0\u3001\u5f3a\u6548\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u00a0\u5177\u5907\u5e7f\u8c31\u6291\u5236\u80fd\u529b\u548c\u5353\u8d8a\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\u3002\u6b64\u6b21ASCO\u5927\u4f1a\u516c\u5e03\u7684\u2160\/\u2161\u671f\u7814\u7a76\u6570\u636e\u63d0\u793a\u5176\u9488\u5bf9EGFR TKI\u8010\u836f\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5177\u6709\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\u548c\u8010\u53d7\u6027\uff0c\u7279\u522b\u662f\u5176\u6cbb\u7597\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u6301\u4e45\u7684\u7f13\u89e3\u7597\u6548\u4ee4\u4eba\u9f13\u821e\u3002\u76ee\u524d\uff0cTIAN-SHAN2\u7814\u7a76\u6b63\u6301\u7eed\u63a8\u8fdb\uff0c\u65e8\u5728\u8fdb\u4e00\u6b65\u9a8c\u8bc1DZD6008\u5728\u66f4\u5e7f\u6cdb\u4eba\u7fa4\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff0c\u8fd9\u9879\u7814\u7a76\u6709\u671b\u4e3a\u665a\u671f\u80ba\u764c\u60a3\u8005\u6784\u5efa\u66f4\u5b8c\u6574\u7684\u8010\u836f\u540e\u6cbb\u7597\u751f\u6001\u94fe\uff0c\u63a8\u52a8\u80ba\u764c\u7cbe\u51c6\u6cbb\u7597\u8fdb\u5165\u65b0\u9636\u6bb5\u3002&#8221; \u8fea\u54f2\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5f20\u5c0f\u6797\u535a\u58eb\u8868\u793a\uff1a&#8221;\u672c\u6b21ASCO\u5927\u4f1a\u4e0a\u516c\u5e03\u7684DZD8586\u548cDZD6008\u591a\u9879\u4e34\u5e8a\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u5f70\u663e\u4e86\u8fea\u54f2\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u7684\u96be\u6cbb\u6027\u80bf\u7624\u9886\u57df\u7684\u7814\u53d1\u5b9e\u529b\u4e0e\u5168\u7403\u5dee\u5f02\u6027\u7ade\u4e89\u4f18\u52bf\u3002\u5c24\u5176\u662fDZD8586\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u60a3\u8005\u7597\u6548\u663e\u8457\uff0c\u4e3a\u6211\u4eec\u63a5\u4e0b\u6765\u63a8\u8fdbDZD8586\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u6ce8\u5165\u4e86\u5de8\u5927\u7684\u4fe1\u5fc3\u4e0e\u52a8\u529b\u3002\u672a\u6765\uff0c\u6211\u4eec\u5c06\u6301\u7eed\u52a0\u901f\u8fd9\u4e24\u6b3e\u6838\u5fc3\u4ea7\u54c1\u7684\u5168\u7403\u5f00\u53d1\u6b65\u4f10\uff0c\u671f\u5f85\u80fd\u591f\u7ed9B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7597\u65b0\u9009\u62e9\u3002&#8221; \u5173\u4e8eDZD8586 DZD8586\u662f\u4e00\u6b3e\u5168\u7403\u9996\u521b\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u975e\u5171\u4ef7LYN\/BTK\u53cc\u9776\u70b9\u6291\u5236\u5242\uff0c\u5bf9\u5176\u4ed6TEC\u5bb6\u65cf\u6fc0\u9176\uff08TEC\u3001ITK\u3001TXK\u548cBMX\uff09\u5177\u6709\u9ad8\u9009\u62e9\u6027\uff0c\u53ef\u540c\u65f6\u963b\u65ad\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u4f9d\u8d56\u6027\u548c\u975e\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\uff0c\u6709\u6548\u6291\u5236\u591a\u79cdB\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u4e9a\u578b\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002 \u5c3d\u7ba1\u73b0\u6709BTK\u6291\u5236\u5242\u5bf9\u90e8\u5206B-NHL\u4e9a\u578b\u4e34\u5e8a\u7597\u6548\u663e\u8457\uff0c\u4f46\u8010\u836f\u6027\u4e00\u76f4\u662f\u4e34\u5e8a\u4e00\u5927\u96be\u9898\u3002\u4e3b\u8981\u7531\u4e24\u79cd\u673a\u5236\u5f15\u53d1\uff1a\u4e00\u79cd\u662fC481X BTK\u7a81\u53d8\uff0c\u53e6\u4e00\u79cd\u5219\u662f\u975eBTK\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\u6fc0\u6d3b\u3002\u5f53\u524d\uff0c\u5c1a\u65e0\u836f\u7269\u80fd\u540c\u65f6\u5e94\u5bf9\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u3002\u6b64\u5916\uff0c\u867d\u7136BTK\u964d\u89e3\u5242\u5728\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\uff0c\u7a81\u53d8\u76f8\u5173\u7684\u8010\u836f\u5df2\u6709\u62a5\u9053\uff0c\u4e14\u964d\u89e3\u5242\u76f8\u5173\u7684\u6bd2\u526f\u53cd\u5e94\u53ef\u80fd\u5f71\u54cd\u4e34\u5e8a\u7684\u957f\u671f\u5e94\u7528\u3002\u65e2\u5f80\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0cDZD8586\u5177\u6709\u826f\u597d\u7684\u53e3\u670d\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6e17\u900f\u80fd\u529b\uff0c\u80fd\u5168\u9762\u963b\u65adBCR\u4fe1\u53f7\u901a\u8def\uff0c\u6cbb\u7597\u7531\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u5f15\u53d1\u7684B-NHL\uff0c\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u826f\u597d\uff0c\u5e76\u5728\u591a\u79cdB-NHL\u4e9a\u578b\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\u3002 \u5173\u4e8eDZD6008 DZD6008\u662f\u4e00\u6b3e\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5168\u65b0\u7684\u3001\u9ad8\u9009\u62e9\u6027\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\uff0c\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u80fd\u6709\u6548\u6291\u5236\u591a\u79cdEGFR\u7a81\u53d8\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002\u5f53\u524d\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09EGFR TKI\u8010\u836f\u673a\u5236\u672a\u660e\uff0c\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\u3002\u540c\u65f6\uff0c\u8111\u8f6c\u79fb\u662f\u5bfc\u81f4\u75be\u75c5\u8fdb\u5c55\u53ca\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c23%-30%\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5728\u521d\u6b21\u8bca\u65ad\u65f6\u5373\u5b58\u5728\u8111\u8f6c\u79fb\uff0c\u8bca\u65ad\u540e3\u5e74\u5185\u8111\u8f6c\u79fb\u7684\u98ce\u9669\u53ef\u80fd\u589e\u81f329.4%-60.3%\u3002 \u76ee\u524d\uff0c\u9488\u5bf9\u4e09\u4ee3EGFR TKI\u8010\u836fNSCLC\u7684\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u7684\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\uff0cDZD6008\u6709\u671b\u586b\u8865\u8be5\u9886\u57df\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002DZD6008\u5728\u5df2\u6709\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5b8c\u5168\u9a8c\u8bc1\u4e86\u8be5\u5206\u5b50\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u5728\u4e09\u4ee3EGFR TKI\u548c\u591a\u7ebf\u6cbb\u7597\u5931\u8d25\u53ca\u8111\u8f6c\u79fb\u7684\u75c5\u4eba\u4e2d\u663e\u793a\u4f18\u5f02\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002 \u5173\u4e8e\u8fea\u54f2\u533b\u836f \u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u662f\u4e00\u5bb6\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u3001\u514d\u75ab\u6027\u75be\u75c5\u9886\u57df\u521b\u65b0\u7597\u6cd5\u7684\u7814\u7a76\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u516c\u53f8\u575a\u6301\u6e90\u5934\u521b\u65b0\u7684\u7814\u53d1\u7406\u5ff5\uff0c\u4ee5\u63a8\u51fa\u5168\u7403\u9996\u521b\u836f\u7269\uff08First-in-class\uff09\u548c\u5177\u6709\u7a81\u7834\u6027\u6f5c\u529b\u7684\u6cbb\u7597\u65b9\u6cd5\u4e3a\u76ee\u6807\uff0c\u65e8\u5728\u586b\u8865\u5168\u7403\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u57fa\u4e8e\u884c\u4e1a\u9886\u5148\u7684\u8f6c\u5316\u79d1\u5b66\u548c\u65b0\u836f\u5206\u5b50\u8bbe\u8ba1\u4e0e\u7b5b\u9009\u6280\u672f\u5e73\u53f0\uff0c\u516c\u53f8\u5df2\u5efa\u7acb\u4e86\u4e03\u6b3e\u5177\u5907\u5168\u7403\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d\u4e24\u5927\u5904\u4e8e\u5168\u7403\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u9886\u5148\u4ea7\u54c1\uff0c\u5747\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u5173\u6ce8\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a\u8fea\u54f2Dizal\uff0c\u6216\u8bbf\u95eehttps:\/\/www.dizalpharma.com\u3002 \u524d\u77bb\u6027\u58f0\u660e \u672c\u65b0\u95fb\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u8fd9\u4e9b\u8868\u8ff0\u672c\u8d28\u4e0a\u5177\u6709\u76f8\u5f53\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u3002\u5728\u4f7f\u7528&#8221;\u9884\u671f&#8221;\u3001&#8221;\u76f8\u4fe1&#8221;\u3001&#8221;\u9884\u6d4b&#8221;\u3001&#8221;\u671f\u671b&#8221;\u3001&#8221;\u6253\u7b97&#8221;\u3001&#8221;\u6709\u671b&#8221;\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u65f6\uff0c\u51e1\u4e0e\u672c\u516c\u53f8\u6709\u5173\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c5e\u524d\u77bb\u6027\u8868\u8ff0\u3002 \u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u672a\u6765\u4e8b\u52a1\u7684\u73b0\u6709\u770b\u6cd5\u3001\u5047\u8bbe\u3001\u671f\u671b\u3001\u4f30\u8ba1\u3001\u9884\u6d4b\u548c\u7406\u89e3\u3002\u8fd9\u4e9b\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u53d1\u5c55\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002 \u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u5458\u6982\u4e0d\u627f\u62c5\uff08a\uff09\u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7f51\u7ad9\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u4e49\u52a1\uff1b\u53ca\uff08b\uff09\u00a0\u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5b9e\u73b0\u6216\u53d8\u6210\u4e0d\u6b63\u786e\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8d23\u4efb\u3002 \u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8bf7\u8054\u7cfb\u6295\u8d44\u8005\u5173\u7cfb\uff1air@dizalpharma.com\u00a0\u00a0\u5546\u52a1\u5408\u4f5c\uff1abd@dizalpharma.com\u00a0 \u00a0\u5a92\u4f53\u8054\u7edc\uff1apr@dizalpharma.com\u00a0 SOURCE \u8fea\u54f2\u533b\u836f<\/p>\n","protected":false},"author":0,"featured_media":11514,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-11513","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u8fea\u54f2\u533b\u836f\u95ea\u8000asco\uff0cdzd8586\u3001dzd6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u548c\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027DZD6008\uff0c\u65b0\u4e00\u4ee3\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u5355\u836f\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u4e2d\uff0c\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u4e14\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3001\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027 \u4e0a\u6d772025\u5e745\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 2025\u5e745\u670823\u65e5\uff0c\u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u4e24\u6b3e\u6e90\u5934\u521b\u65b0\u4ea7\u54c1DZD8586\u548cDZD6008\u5c06\u4e8e2025\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\uff0c\u5206\u522b\u5c55\u793a\u5728B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u9886\u57df\u76843\u9879\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\uff0c\u5f70\u663e\u8fea\u54f2\u533b\u836f\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u5dee\u5f02\u5316\u7ade\u4e89\u4e2d\u7684\u65b0\u4f18\u52bf\u3002\u5176\u4e2d\uff0c\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u7684\u6c47\u603b\u5206\u6790\u6210\u679c\u5c06\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u3002 DZD8586\uff1a\u6709\u671b\u4e3aB-NHL\u60a3\u8005\u5e26\u6765\u5168\u65b0\u6cbb\u7597\u9009\u62e9 DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u7684\u4e00\u9879\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u6c47\u603b\u5206\u6790\uff0c\u5c06\u5728\u672c\u6b21ASCO\u5927\u4f1a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff08\u6458\u8981\u7f16\u53f7\uff1a7010\uff09\u3002\u622a\u81f32025\u5e744\u67084\u65e5\uff0c\u7814\u7a76\u5171\u5165\u7ec451\u4f8b\u590d\u53d1\/\u96be\u6cbb\uff08r\/r\uff09CLL\/SLL\u60a3\u8005\u63a5\u53d7DZD8586\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u572850mg\u5242\u91cf\u4e0b\uff0cDZD8586\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\uff0c\u4e14\u5b89\u5168\u6027\u53ef\u63a7\uff1a \u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u9ad8\u8fbe84.2%\uff0c\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242\u3001Bcl-2\u6291\u5236\u5242\u6216BTK\u964d\u89e3\u5242\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u5206\u522b\u89c2\u5bdf\u523082.4%\u300183.3%\u548c50%\u7684\u80bf\u7624\u7f13\u89e3\u5728\u643a\u5e26\u7ecf\u5178BTK\u8010\u836f\u7a81\u53d8\uff08C481X\uff09\uff0c\u4ee5\u53ca\u5305\u62ecBTK\u6fc0\u9176\u5931\u6d3b\u7a81\u53d8\u7b49\u5176\u4ed6BTK\u7a81\u53d8\u7684\u60a3\u8005\u4e2d\uff0c\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u89c2\u5bdf\u5230\u6301\u4e45\u7f13\u89e3\uff0c\u9884\u8ba19\u4e2a\u6708\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u7387\u4e3a83.3%\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u5c1a\u672a\u6210\u719f\uff0c78.9%\u7684\u60a3\u8005\u4ecd\u5728\u6301\u7eed\u63a5\u53d7DZD8586\u6cbb\u7597 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\u674e\u5efa\u52c7\u6559\u6388\u8868\u793a\uff1a&#8221;DZD8586\u901a\u8fc7LYN\/BTK\u975e\u5171\u4ef7\u53cc\u9776\u70b9\u963b\u65ad\u4f18\u52bf\uff0c\u80fd\u591f\u5728\u590d\u53d1\/\u96be\u6cbb\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r CLL\/SLL\uff09\u60a3\u8005\u4e2d\u53d6\u5f97\u7a81\u7834\uff0c\u4ece\u7814\u7a76\u7ed3\u679c\u770b\u5176\u5177\u5907\u653b\u514b\u591a\u91cd\u8010\u836f\uff0c\u89c4\u907f\u4f20\u7edfBTK\u6291\u5236\u5242\u56e0\u9776\u70b9\u8017\u7aed\u6216\u65c1\u8def\u6fc0\u6d3b\u5bfc\u81f4\u7684\u8010\u836f\uff0c\u4e3a\u6cbb\u7597\u63d0\u4f9b\u65b0\u673a\u9047\u548c\u65b0\u7b56\u7565\uff0c\u671f\u5f85\u540e\u7eed\u7814\u7a76\u4e2d\u80fd\u6709\u66f4\u591a\u597d\u7684\u7ed3\u679c\u5448\u73b0\u3002&#8221; \u6b64\u5916\uff0cDZD8586\u53e6\u4e00\u9879\u5c06\u5728ASCO\u5927\u4f1a\u5c55\u793a\u7684\u662f\u5176\u5355\u836f\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff08\u6458\u8981\u7f16\u53f7\uff1ae19050\uff09\u3002\u5165\u7ec4\u7684r\/r DLBCL\u60a3\u8005\u65e2\u5f80\u63a5\u53d7\u8fc71\u81f34\u7ebf\u7684\u7cfb\u7edf\u6027\u6cbb\u7597\uff0c\u4e14\u6cbb\u7597\u65b9\u6848\u5747\u5305\u542b\u4ee5\u84bd\u73af\u7c7b\u836f\u7269\u8054\u5408\u6297CD20\u5355\u6297\u4e3a\u57fa\u7840\u7684\u5316\u7597\u514d\u75ab\u6cbb\u7597\u3002\u7814\u7a76\u6570\u636e\u663e\u793a\uff1a\u572850 mg\u548c75 mg\u5242\u91cf\u4e0b\uff0cDZD8586\u9488\u5bf9r\/r DLBCL\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e14\u5728GCB\u4e9a\u578b\u53ca\u975eGCB\u4e9a\u578b\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u3002\u8be5\u7814\u7a76\u7684\u6700\u65b0\u6570\u636e\u5c06\u57282025\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8840\u6db2\u75c5\u533b\u9662\u90b1\u5f55\u8d35\u6559\u6388\u8868\u793a\uff1a&#8221;\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u591a\u7ebf\u6cbb\u7597\u540e\u7684\u8010\u836f\u95ee\u9898\u4e00\u76f4\u56f0\u6270\u4e34\u5e8a\u8bca\u7597\uff0cDZD8586\u4f5c\u4e3a\u53cc\u9776\u70b9\u975e\u5171\u4ef7\u6291\u5236\u5242\uff0c\u5728GCB\/\u975eGCB\u4e9a\u578b\u4e2d\u5747\u6709\u6548\uff0c\u540c\u65f6\u80fd\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u5177\u5907\u4e2d\u67a2\u6cbb\u7597\u6f5c\u529b\uff0c\u6216\u53ef\u89e3\u51b3\u4f34\u4e2d\u67a2\u4fb5\u72af\u60a3\u8005\u7684\u6cbb\u7597\u75db\u70b9\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u6765\u53ef\u671f\u3002&#8221; DZD6008\uff1a\u6709\u671b\u586b\u8865NSCLC\u9886\u57df\u672a\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42 \u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9886\u57df\uff0cDZD6008\u5355\u836f\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u4e34\u5e8a\u524d\u548c\u2160\/\u2161\u671f\u9996\u6b21\u4eba\u4f53\u7814\u7a76\uff08TIAN-SHAN2\uff09\u7684\u65e9\u671f\u4e34\u5e8a\u79ef\u6781\u6570\u636e\uff0c\u4e5f\u5c06\u4eae\u76f8ASCO\u5927\u4f1a\uff08\u6458\u8981\u7f16\u53f7\uff1a8616\uff09\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0cDZD6008\u5bf9\u4e8eEGFR\u654f\u611f\u7a81\u53d8\uff08L858R\/del19\uff09\u3001\u8010\u836f\u53cc\u7a81\u53d8\uff08T790M\u548cL858R\/del19\uff09\u4ee5\u53ca\u4e09\u91cd\u7a81\u53d8\uff08C797X\u3001T790M\u548cL858R\/del19\uff09\u5177\u6709\u5f3a\u6548\u4e14\u76f8\u4f3c\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5bf9\u91ce\u751f\u578bEGFR\u5177\u6709\u8d85\u8fc750\u500d\u7684\u9ad8\u9009\u62e9\u6027\u3002 TIAN-SHAN2\uff0c\u4e00\u9879\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u622a\u81f32025\u5e743\u670831\u65e5\uff0cDZD6008\u5355\u836f\u5728\u5165\u7ec4\u768412\u4f8b\u65e2\u5f80\u7ecf\u8fc7\u5145\u5206\u6cbb\u7597\uff08\u4e2d\u4f4d4.5\u7ebf\uff0c\u8303\u56f42-8\u7ebf\uff09\u3001\u643a\u5e26\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u665a\u671fNSCLC\u60a3\u8005\u4e2d\uff0c\u8868\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u5e76\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u63a5\u53d7DZD6008\u6cbb\u7597\u540e\uff0c10\u4f8b\u60a3\u8005\uff0883.3%\uff09\u663e\u793a\u9776\u75c5\u7076\u80bf\u7624\u7f29\u5c0f\u3002\u5728\u8d77\u59cb\u5242\u91cf20 mg\u53ca\u66f4\u9ad8\u5242\u91cf\u7ec4\uff0c\u643a\u5e26\u591a\u79cd\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u60a3\u8005\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u6b64\u5916\uff0c\u4e0e\u4e34\u5e8a\u524d\u6570\u636e\u4e00\u81f4\uff0cDZD6008\u5728\u60a3\u8005\u4f53\u5185\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\uff0c\u8111\u810a\u6db2\u4e2d\u836f\u7269\u6d53\u5ea6\u4e0e\u6e38\u79bb\u8840\u6d46\u836f\u7269\u6d53\u5ea6\u6bd4\u503c\u8d85\u8fc71\uff0c\u5728\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u4e2d\u4e5f\u8bc1\u5b9e\u4e86\u5176\u6301\u4e45\u7684\u7597\u6548\u53cd\u5e94\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u5317\u4eac\u534f\u548c\u533b\u9662\u738b\u5b5f\u662d\u6559\u6388\u8868\u793a\uff1a&#8221;DZD6008\u4f5c\u4e3a\u4e00\u6b3e\u5168\u65b0\u3001\u5f3a\u6548\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u00a0\u5177\u5907\u5e7f\u8c31\u6291\u5236\u80fd\u529b\u548c\u5353\u8d8a\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\u3002\u6b64\u6b21ASCO\u5927\u4f1a\u516c\u5e03\u7684\u2160\/\u2161\u671f\u7814\u7a76\u6570\u636e\u63d0\u793a\u5176\u9488\u5bf9EGFR TKI\u8010\u836f\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5177\u6709\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\u548c\u8010\u53d7\u6027\uff0c\u7279\u522b\u662f\u5176\u6cbb\u7597\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u6301\u4e45\u7684\u7f13\u89e3\u7597\u6548\u4ee4\u4eba\u9f13\u821e\u3002\u76ee\u524d\uff0cTIAN-SHAN2\u7814\u7a76\u6b63\u6301\u7eed\u63a8\u8fdb\uff0c\u65e8\u5728\u8fdb\u4e00\u6b65\u9a8c\u8bc1DZD6008\u5728\u66f4\u5e7f\u6cdb\u4eba\u7fa4\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff0c\u8fd9\u9879\u7814\u7a76\u6709\u671b\u4e3a\u665a\u671f\u80ba\u764c\u60a3\u8005\u6784\u5efa\u66f4\u5b8c\u6574\u7684\u8010\u836f\u540e\u6cbb\u7597\u751f\u6001\u94fe\uff0c\u63a8\u52a8\u80ba\u764c\u7cbe\u51c6\u6cbb\u7597\u8fdb\u5165\u65b0\u9636\u6bb5\u3002&#8221; \u8fea\u54f2\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5f20\u5c0f\u6797\u535a\u58eb\u8868\u793a\uff1a&#8221;\u672c\u6b21ASCO\u5927\u4f1a\u4e0a\u516c\u5e03\u7684DZD8586\u548cDZD6008\u591a\u9879\u4e34\u5e8a\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u5f70\u663e\u4e86\u8fea\u54f2\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u7684\u96be\u6cbb\u6027\u80bf\u7624\u9886\u57df\u7684\u7814\u53d1\u5b9e\u529b\u4e0e\u5168\u7403\u5dee\u5f02\u6027\u7ade\u4e89\u4f18\u52bf\u3002\u5c24\u5176\u662fDZD8586\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u60a3\u8005\u7597\u6548\u663e\u8457\uff0c\u4e3a\u6211\u4eec\u63a5\u4e0b\u6765\u63a8\u8fdbDZD8586\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u6ce8\u5165\u4e86\u5de8\u5927\u7684\u4fe1\u5fc3\u4e0e\u52a8\u529b\u3002\u672a\u6765\uff0c\u6211\u4eec\u5c06\u6301\u7eed\u52a0\u901f\u8fd9\u4e24\u6b3e\u6838\u5fc3\u4ea7\u54c1\u7684\u5168\u7403\u5f00\u53d1\u6b65\u4f10\uff0c\u671f\u5f85\u80fd\u591f\u7ed9B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7597\u65b0\u9009\u62e9\u3002&#8221; \u5173\u4e8eDZD8586 DZD8586\u662f\u4e00\u6b3e\u5168\u7403\u9996\u521b\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u975e\u5171\u4ef7LYN\/BTK\u53cc\u9776\u70b9\u6291\u5236\u5242\uff0c\u5bf9\u5176\u4ed6TEC\u5bb6\u65cf\u6fc0\u9176\uff08TEC\u3001ITK\u3001TXK\u548cBMX\uff09\u5177\u6709\u9ad8\u9009\u62e9\u6027\uff0c\u53ef\u540c\u65f6\u963b\u65ad\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u4f9d\u8d56\u6027\u548c\u975e\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\uff0c\u6709\u6548\u6291\u5236\u591a\u79cdB\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u4e9a\u578b\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002 \u5c3d\u7ba1\u73b0\u6709BTK\u6291\u5236\u5242\u5bf9\u90e8\u5206B-NHL\u4e9a\u578b\u4e34\u5e8a\u7597\u6548\u663e\u8457\uff0c\u4f46\u8010\u836f\u6027\u4e00\u76f4\u662f\u4e34\u5e8a\u4e00\u5927\u96be\u9898\u3002\u4e3b\u8981\u7531\u4e24\u79cd\u673a\u5236\u5f15\u53d1\uff1a\u4e00\u79cd\u662fC481X BTK\u7a81\u53d8\uff0c\u53e6\u4e00\u79cd\u5219\u662f\u975eBTK\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\u6fc0\u6d3b\u3002\u5f53\u524d\uff0c\u5c1a\u65e0\u836f\u7269\u80fd\u540c\u65f6\u5e94\u5bf9\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u3002\u6b64\u5916\uff0c\u867d\u7136BTK\u964d\u89e3\u5242\u5728\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\uff0c\u7a81\u53d8\u76f8\u5173\u7684\u8010\u836f\u5df2\u6709\u62a5\u9053\uff0c\u4e14\u964d\u89e3\u5242\u76f8\u5173\u7684\u6bd2\u526f\u53cd\u5e94\u53ef\u80fd\u5f71\u54cd\u4e34\u5e8a\u7684\u957f\u671f\u5e94\u7528\u3002\u65e2\u5f80\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0cDZD8586\u5177\u6709\u826f\u597d\u7684\u53e3\u670d\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6e17\u900f\u80fd\u529b\uff0c\u80fd\u5168\u9762\u963b\u65adBCR\u4fe1\u53f7\u901a\u8def\uff0c\u6cbb\u7597\u7531\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u5f15\u53d1\u7684B-NHL\uff0c\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u826f\u597d\uff0c\u5e76\u5728\u591a\u79cdB-NHL\u4e9a\u578b\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\u3002 \u5173\u4e8eDZD6008 DZD6008\u662f\u4e00\u6b3e\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5168\u65b0\u7684\u3001\u9ad8\u9009\u62e9\u6027\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\uff0c\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u80fd\u6709\u6548\u6291\u5236\u591a\u79cdEGFR\u7a81\u53d8\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002\u5f53\u524d\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09EGFR TKI\u8010\u836f\u673a\u5236\u672a\u660e\uff0c\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\u3002\u540c\u65f6\uff0c\u8111\u8f6c\u79fb\u662f\u5bfc\u81f4\u75be\u75c5\u8fdb\u5c55\u53ca\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c23%-30%\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5728\u521d\u6b21\u8bca\u65ad\u65f6\u5373\u5b58\u5728\u8111\u8f6c\u79fb\uff0c\u8bca\u65ad\u540e3\u5e74\u5185\u8111\u8f6c\u79fb\u7684\u98ce\u9669\u53ef\u80fd\u589e\u81f329.4%-60.3%\u3002 \u76ee\u524d\uff0c\u9488\u5bf9\u4e09\u4ee3EGFR TKI\u8010\u836fNSCLC\u7684\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u7684\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\uff0cDZD6008\u6709\u671b\u586b\u8865\u8be5\u9886\u57df\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002DZD6008\u5728\u5df2\u6709\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5b8c\u5168\u9a8c\u8bc1\u4e86\u8be5\u5206\u5b50\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u5728\u4e09\u4ee3EGFR TKI\u548c\u591a\u7ebf\u6cbb\u7597\u5931\u8d25\u53ca\u8111\u8f6c\u79fb\u7684\u75c5\u4eba\u4e2d\u663e\u793a\u4f18\u5f02\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002 \u5173\u4e8e\u8fea\u54f2\u533b\u836f \u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u662f\u4e00\u5bb6\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u3001\u514d\u75ab\u6027\u75be\u75c5\u9886\u57df\u521b\u65b0\u7597\u6cd5\u7684\u7814\u7a76\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u516c\u53f8\u575a\u6301\u6e90\u5934\u521b\u65b0\u7684\u7814\u53d1\u7406\u5ff5\uff0c\u4ee5\u63a8\u51fa\u5168\u7403\u9996\u521b\u836f\u7269\uff08First-in-class\uff09\u548c\u5177\u6709\u7a81\u7834\u6027\u6f5c\u529b\u7684\u6cbb\u7597\u65b9\u6cd5\u4e3a\u76ee\u6807\uff0c\u65e8\u5728\u586b\u8865\u5168\u7403\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u57fa\u4e8e\u884c\u4e1a\u9886\u5148\u7684\u8f6c\u5316\u79d1\u5b66\u548c\u65b0\u836f\u5206\u5b50\u8bbe\u8ba1\u4e0e\u7b5b\u9009\u6280\u672f\u5e73\u53f0\uff0c\u516c\u53f8\u5df2\u5efa\u7acb\u4e86\u4e03\u6b3e\u5177\u5907\u5168\u7403\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d\u4e24\u5927\u5904\u4e8e\u5168\u7403\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u9886\u5148\u4ea7\u54c1\uff0c\u5747\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u5173\u6ce8\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a\u8fea\u54f2Dizal\uff0c\u6216\u8bbf\u95eehttps:\/\/www.dizalpharma.com\u3002 \u524d\u77bb\u6027\u58f0\u660e \u672c\u65b0\u95fb\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u8fd9\u4e9b\u8868\u8ff0\u672c\u8d28\u4e0a\u5177\u6709\u76f8\u5f53\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u3002\u5728\u4f7f\u7528&#8221;\u9884\u671f&#8221;\u3001&#8221;\u76f8\u4fe1&#8221;\u3001&#8221;\u9884\u6d4b&#8221;\u3001&#8221;\u671f\u671b&#8221;\u3001&#8221;\u6253\u7b97&#8221;\u3001&#8221;\u6709\u671b&#8221;\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u65f6\uff0c\u51e1\u4e0e\u672c\u516c\u53f8\u6709\u5173\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c5e\u524d\u77bb\u6027\u8868\u8ff0\u3002 \u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u672a\u6765\u4e8b\u52a1\u7684\u73b0\u6709\u770b\u6cd5\u3001\u5047\u8bbe\u3001\u671f\u671b\u3001\u4f30\u8ba1\u3001\u9884\u6d4b\u548c\u7406\u89e3\u3002\u8fd9\u4e9b\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u53d1\u5c55\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002 \u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u5458\u6982\u4e0d\u627f\u62c5\uff08a\uff09\u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7f51\u7ad9\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u4e49\u52a1\uff1b\u53ca\uff08b\uff09\u00a0\u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5b9e\u73b0\u6216\u53d8\u6210\u4e0d\u6b63\u786e\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8d23\u4efb\u3002 \u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8bf7\u8054\u7cfb\u6295\u8d44\u8005\u5173\u7cfb\uff1air@dizalpharma.com\u00a0\u00a0\u5546\u52a1\u5408\u4f5c\uff1abd@dizalpharma.com\u00a0 \u00a0\u5a92\u4f53\u8054\u7edc\uff1apr@dizalpharma.com\u00a0 SOURCE \u8fea\u54f2\u533b\u836f\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u8fea\u54f2\u533b\u836f\u95ea\u8000asco\uff0cdzd8586\u3001dzd6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-23T08:04:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"144\" \/>\n\t<meta property=\"og:image:height\" content=\"81\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/\",\"name\":\"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN\",\"isPartOf\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg\",\"datePublished\":\"2025-05-23T08:04:00+00:00\",\"dateModified\":\"2025-05-23T08:04:00+00:00\",\"author\":{\"@id\":\"\"},\"breadcrumb\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg\",\"contentUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg\",\"width\":144,\"height\":81},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/moneycompass.com.my\/cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/\",\"name\":\"Money Compass CN\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/moneycompass.com.my\/cn\/\u8fea\u54f2\u533b\u836f\u95ea\u8000asco\uff0cdzd8586\u3001dzd6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\/","og_locale":"en_US","og_type":"article","og_title":"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN","og_description":"DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u548c\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027DZD6008\uff0c\u65b0\u4e00\u4ee3\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u5355\u836f\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u4e2d\uff0c\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u4e14\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3001\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027 \u4e0a\u6d772025\u5e745\u670823\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 2025\u5e745\u670823\u65e5\uff0c\u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u4e24\u6b3e\u6e90\u5934\u521b\u65b0\u4ea7\u54c1DZD8586\u548cDZD6008\u5c06\u4e8e2025\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u4e0a\uff0c\u5206\u522b\u5c55\u793a\u5728B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u9886\u57df\u76843\u9879\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\uff0c\u5f70\u663e\u8fea\u54f2\u533b\u836f\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u5dee\u5f02\u5316\u7ade\u4e89\u4e2d\u7684\u65b0\u4f18\u52bf\u3002\u5176\u4e2d\uff0c\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u7684\u6c47\u603b\u5206\u6790\u6210\u679c\u5c06\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u3002 DZD8586\uff1a\u6709\u671b\u4e3aB-NHL\u60a3\u8005\u5e26\u6765\u5168\u65b0\u6cbb\u7597\u9009\u62e9 DZD8586\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u7684\u4e00\u9879\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u6c47\u603b\u5206\u6790\uff0c\u5c06\u5728\u672c\u6b21ASCO\u5927\u4f1a\u8fdb\u884c\u53e3\u5934\u62a5\u544a\uff08\u6458\u8981\u7f16\u53f7\uff1a7010\uff09\u3002\u622a\u81f32025\u5e744\u67084\u65e5\uff0c\u7814\u7a76\u5171\u5165\u7ec451\u4f8b\u590d\u53d1\/\u96be\u6cbb\uff08r\/r\uff09CLL\/SLL\u60a3\u8005\u63a5\u53d7DZD8586\u6cbb\u7597\u3002\u7ed3\u679c\u663e\u793a\uff0c\u572850mg\u5242\u91cf\u4e0b\uff0cDZD8586\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u91cd\u5ea6\u6cbb\u7597\u7684CLL\/SLL\u60a3\u8005\u5c55\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\uff0c\u4e14\u5b89\u5168\u6027\u53ef\u63a7\uff1a \u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u9ad8\u8fbe84.2%\uff0c\u5728\u65e2\u5f80\u63a5\u53d7\u8fc7\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5242\u3001Bcl-2\u6291\u5236\u5242\u6216BTK\u964d\u89e3\u5242\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u5206\u522b\u89c2\u5bdf\u523082.4%\u300183.3%\u548c50%\u7684\u80bf\u7624\u7f13\u89e3\u5728\u643a\u5e26\u7ecf\u5178BTK\u8010\u836f\u7a81\u53d8\uff08C481X\uff09\uff0c\u4ee5\u53ca\u5305\u62ecBTK\u6fc0\u9176\u5931\u6d3b\u7a81\u53d8\u7b49\u5176\u4ed6BTK\u7a81\u53d8\u7684\u60a3\u8005\u4e2d\uff0c\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u89c2\u5bdf\u5230\u6301\u4e45\u7f13\u89e3\uff0c\u9884\u8ba19\u4e2a\u6708\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u7387\u4e3a83.3%\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u5c1a\u672a\u6210\u719f\uff0c78.9%\u7684\u60a3\u8005\u4ecd\u5728\u6301\u7eed\u63a5\u53d7DZD8586\u6cbb\u7597 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\u674e\u5efa\u52c7\u6559\u6388\u8868\u793a\uff1a&#8221;DZD8586\u901a\u8fc7LYN\/BTK\u975e\u5171\u4ef7\u53cc\u9776\u70b9\u963b\u65ad\u4f18\u52bf\uff0c\u80fd\u591f\u5728\u590d\u53d1\/\u96be\u6cbb\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r CLL\/SLL\uff09\u60a3\u8005\u4e2d\u53d6\u5f97\u7a81\u7834\uff0c\u4ece\u7814\u7a76\u7ed3\u679c\u770b\u5176\u5177\u5907\u653b\u514b\u591a\u91cd\u8010\u836f\uff0c\u89c4\u907f\u4f20\u7edfBTK\u6291\u5236\u5242\u56e0\u9776\u70b9\u8017\u7aed\u6216\u65c1\u8def\u6fc0\u6d3b\u5bfc\u81f4\u7684\u8010\u836f\uff0c\u4e3a\u6cbb\u7597\u63d0\u4f9b\u65b0\u673a\u9047\u548c\u65b0\u7b56\u7565\uff0c\u671f\u5f85\u540e\u7eed\u7814\u7a76\u4e2d\u80fd\u6709\u66f4\u591a\u597d\u7684\u7ed3\u679c\u5448\u73b0\u3002&#8221; \u6b64\u5916\uff0cDZD8586\u53e6\u4e00\u9879\u5c06\u5728ASCO\u5927\u4f1a\u5c55\u793a\u7684\u662f\u5176\u5355\u836f\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08r\/r DLBCL\uff09\u7684\u2161\u671f\u4e34\u5e8a\u7814\u7a76\uff08\u6458\u8981\u7f16\u53f7\uff1ae19050\uff09\u3002\u5165\u7ec4\u7684r\/r DLBCL\u60a3\u8005\u65e2\u5f80\u63a5\u53d7\u8fc71\u81f34\u7ebf\u7684\u7cfb\u7edf\u6027\u6cbb\u7597\uff0c\u4e14\u6cbb\u7597\u65b9\u6848\u5747\u5305\u542b\u4ee5\u84bd\u73af\u7c7b\u836f\u7269\u8054\u5408\u6297CD20\u5355\u6297\u4e3a\u57fa\u7840\u7684\u5316\u7597\u514d\u75ab\u6cbb\u7597\u3002\u7814\u7a76\u6570\u636e\u663e\u793a\uff1a\u572850 mg\u548c75 mg\u5242\u91cf\u4e0b\uff0cDZD8586\u9488\u5bf9r\/r DLBCL\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e14\u5728GCB\u4e9a\u578b\u53ca\u975eGCB\u4e9a\u578b\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u7f13\u89e3\u3002\u8be5\u7814\u7a76\u7684\u6700\u65b0\u6570\u636e\u5c06\u57282025\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u4e0a\u516c\u5e03\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8840\u6db2\u75c5\u533b\u9662\u90b1\u5f55\u8d35\u6559\u6388\u8868\u793a\uff1a&#8221;\u5f25\u6f2b\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u591a\u7ebf\u6cbb\u7597\u540e\u7684\u8010\u836f\u95ee\u9898\u4e00\u76f4\u56f0\u6270\u4e34\u5e8a\u8bca\u7597\uff0cDZD8586\u4f5c\u4e3a\u53cc\u9776\u70b9\u975e\u5171\u4ef7\u6291\u5236\u5242\uff0c\u5728GCB\/\u975eGCB\u4e9a\u578b\u4e2d\u5747\u6709\u6548\uff0c\u540c\u65f6\u80fd\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u5177\u5907\u4e2d\u67a2\u6cbb\u7597\u6f5c\u529b\uff0c\u6216\u53ef\u89e3\u51b3\u4f34\u4e2d\u67a2\u4fb5\u72af\u60a3\u8005\u7684\u6cbb\u7597\u75db\u70b9\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u6765\u53ef\u671f\u3002&#8221; DZD6008\uff1a\u6709\u671b\u586b\u8865NSCLC\u9886\u57df\u672a\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42 \u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9886\u57df\uff0cDZD6008\u5355\u836f\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u4e34\u5e8a\u524d\u548c\u2160\/\u2161\u671f\u9996\u6b21\u4eba\u4f53\u7814\u7a76\uff08TIAN-SHAN2\uff09\u7684\u65e9\u671f\u4e34\u5e8a\u79ef\u6781\u6570\u636e\uff0c\u4e5f\u5c06\u4eae\u76f8ASCO\u5927\u4f1a\uff08\u6458\u8981\u7f16\u53f7\uff1a8616\uff09\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0cDZD6008\u5bf9\u4e8eEGFR\u654f\u611f\u7a81\u53d8\uff08L858R\/del19\uff09\u3001\u8010\u836f\u53cc\u7a81\u53d8\uff08T790M\u548cL858R\/del19\uff09\u4ee5\u53ca\u4e09\u91cd\u7a81\u53d8\uff08C797X\u3001T790M\u548cL858R\/del19\uff09\u5177\u6709\u5f3a\u6548\u4e14\u76f8\u4f3c\u7684\u6291\u5236\u4f5c\u7528\uff0c\u5bf9\u91ce\u751f\u578bEGFR\u5177\u6709\u8d85\u8fc750\u500d\u7684\u9ad8\u9009\u62e9\u6027\u3002 TIAN-SHAN2\uff0c\u4e00\u9879\u9488\u5bf9\u65e2\u5f80\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u7684\u2160\/\u2161\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u622a\u81f32025\u5e743\u670831\u65e5\uff0cDZD6008\u5355\u836f\u5728\u5165\u7ec4\u768412\u4f8b\u65e2\u5f80\u7ecf\u8fc7\u5145\u5206\u6cbb\u7597\uff08\u4e2d\u4f4d4.5\u7ebf\uff0c\u8303\u56f42-8\u7ebf\uff09\u3001\u643a\u5e26\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u665a\u671fNSCLC\u60a3\u8005\u4e2d\uff0c\u8868\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u5e76\u6301\u4e45\u7684\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002\u5728\u63a5\u53d7DZD6008\u6cbb\u7597\u540e\uff0c10\u4f8b\u60a3\u8005\uff0883.3%\uff09\u663e\u793a\u9776\u75c5\u7076\u80bf\u7624\u7f29\u5c0f\u3002\u5728\u8d77\u59cb\u5242\u91cf20 mg\u53ca\u66f4\u9ad8\u5242\u91cf\u7ec4\uff0c\u643a\u5e26\u591a\u79cd\u4e0d\u540cEGFR\u7a81\u53d8\u7c7b\u578b\u7684\u60a3\u8005\u4e2d\u5747\u89c2\u5bdf\u5230\u80bf\u7624\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u6b64\u5916\uff0c\u4e0e\u4e34\u5e8a\u524d\u6570\u636e\u4e00\u81f4\uff0cDZD6008\u5728\u60a3\u8005\u4f53\u5185\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\uff0c\u8111\u810a\u6db2\u4e2d\u836f\u7269\u6d53\u5ea6\u4e0e\u6e38\u79bb\u8840\u6d46\u836f\u7269\u6d53\u5ea6\u6bd4\u503c\u8d85\u8fc71\uff0c\u5728\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u4e2d\u4e5f\u8bc1\u5b9e\u4e86\u5176\u6301\u4e45\u7684\u7597\u6548\u53cd\u5e94\u3002 \u4e3b\u8981\u7814\u7a76\u8005\u3001\u5317\u4eac\u534f\u548c\u533b\u9662\u738b\u5b5f\u662d\u6559\u6388\u8868\u793a\uff1a&#8221;DZD6008\u4f5c\u4e3a\u4e00\u6b3e\u5168\u65b0\u3001\u5f3a\u6548\u7684\u9ad8\u9009\u62e9\u6027EGFR TKI\uff0c\u00a0\u5177\u5907\u5e7f\u8c31\u6291\u5236\u80fd\u529b\u548c\u5353\u8d8a\u7684\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\u3002\u6b64\u6b21ASCO\u5927\u4f1a\u516c\u5e03\u7684\u2160\/\u2161\u671f\u7814\u7a76\u6570\u636e\u63d0\u793a\u5176\u9488\u5bf9EGFR TKI\u8010\u836f\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5177\u6709\u826f\u597d\u7684\u6297\u80bf\u7624\u7597\u6548\u548c\u8010\u53d7\u6027\uff0c\u7279\u522b\u662f\u5176\u6cbb\u7597\u57fa\u7ebf\u5b58\u5728\u8111\u8f6c\u79fb\u7684\u60a3\u8005\u6301\u4e45\u7684\u7f13\u89e3\u7597\u6548\u4ee4\u4eba\u9f13\u821e\u3002\u76ee\u524d\uff0cTIAN-SHAN2\u7814\u7a76\u6b63\u6301\u7eed\u63a8\u8fdb\uff0c\u65e8\u5728\u8fdb\u4e00\u6b65\u9a8c\u8bc1DZD6008\u5728\u66f4\u5e7f\u6cdb\u4eba\u7fa4\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff0c\u8fd9\u9879\u7814\u7a76\u6709\u671b\u4e3a\u665a\u671f\u80ba\u764c\u60a3\u8005\u6784\u5efa\u66f4\u5b8c\u6574\u7684\u8010\u836f\u540e\u6cbb\u7597\u751f\u6001\u94fe\uff0c\u63a8\u52a8\u80ba\u764c\u7cbe\u51c6\u6cbb\u7597\u8fdb\u5165\u65b0\u9636\u6bb5\u3002&#8221; \u8fea\u54f2\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5f20\u5c0f\u6797\u535a\u58eb\u8868\u793a\uff1a&#8221;\u672c\u6b21ASCO\u5927\u4f1a\u4e0a\u516c\u5e03\u7684DZD8586\u548cDZD6008\u591a\u9879\u4e34\u5e8a\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u5f70\u663e\u4e86\u8fea\u54f2\u5728\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u7684\u96be\u6cbb\u6027\u80bf\u7624\u9886\u57df\u7684\u7814\u53d1\u5b9e\u529b\u4e0e\u5168\u7403\u5dee\u5f02\u6027\u7ade\u4e89\u4f18\u52bf\u3002\u5c24\u5176\u662fDZD8586\u6cbb\u7597\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u60a3\u8005\u7597\u6548\u663e\u8457\uff0c\u4e3a\u6211\u4eec\u63a5\u4e0b\u6765\u63a8\u8fdbDZD8586\u7684\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u6ce8\u5165\u4e86\u5de8\u5927\u7684\u4fe1\u5fc3\u4e0e\u52a8\u529b\u3002\u672a\u6765\uff0c\u6211\u4eec\u5c06\u6301\u7eed\u52a0\u901f\u8fd9\u4e24\u6b3e\u6838\u5fc3\u4ea7\u54c1\u7684\u5168\u7403\u5f00\u53d1\u6b65\u4f10\uff0c\u671f\u5f85\u80fd\u591f\u7ed9B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7597\u65b0\u9009\u62e9\u3002&#8221; \u5173\u4e8eDZD8586 DZD8586\u662f\u4e00\u6b3e\u5168\u7403\u9996\u521b\u3001\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u975e\u5171\u4ef7LYN\/BTK\u53cc\u9776\u70b9\u6291\u5236\u5242\uff0c\u5bf9\u5176\u4ed6TEC\u5bb6\u65cf\u6fc0\u9176\uff08TEC\u3001ITK\u3001TXK\u548cBMX\uff09\u5177\u6709\u9ad8\u9009\u62e9\u6027\uff0c\u53ef\u540c\u65f6\u963b\u65ad\u5e03\u9c81\u987f\u6c0f\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u4f9d\u8d56\u6027\u548c\u975e\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\uff0c\u6709\u6548\u6291\u5236\u591a\u79cdB\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08B-NHL\uff09\u4e9a\u578b\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002 \u5c3d\u7ba1\u73b0\u6709BTK\u6291\u5236\u5242\u5bf9\u90e8\u5206B-NHL\u4e9a\u578b\u4e34\u5e8a\u7597\u6548\u663e\u8457\uff0c\u4f46\u8010\u836f\u6027\u4e00\u76f4\u662f\u4e34\u5e8a\u4e00\u5927\u96be\u9898\u3002\u4e3b\u8981\u7531\u4e24\u79cd\u673a\u5236\u5f15\u53d1\uff1a\u4e00\u79cd\u662fC481X BTK\u7a81\u53d8\uff0c\u53e6\u4e00\u79cd\u5219\u662f\u975eBTK\u4f9d\u8d56\u6027BCR\u4fe1\u53f7\u901a\u8def\u6fc0\u6d3b\u3002\u5f53\u524d\uff0c\u5c1a\u65e0\u836f\u7269\u80fd\u540c\u65f6\u5e94\u5bf9\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u3002\u6b64\u5916\uff0c\u867d\u7136BTK\u964d\u89e3\u5242\u5728\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\uff0c\u7a81\u53d8\u76f8\u5173\u7684\u8010\u836f\u5df2\u6709\u62a5\u9053\uff0c\u4e14\u964d\u89e3\u5242\u76f8\u5173\u7684\u6bd2\u526f\u53cd\u5e94\u53ef\u80fd\u5f71\u54cd\u4e34\u5e8a\u7684\u957f\u671f\u5e94\u7528\u3002\u65e2\u5f80\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0cDZD8586\u5177\u6709\u826f\u597d\u7684\u53e3\u670d\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6e17\u900f\u80fd\u529b\uff0c\u80fd\u5168\u9762\u963b\u65adBCR\u4fe1\u53f7\u901a\u8def\uff0c\u6cbb\u7597\u7531\u8fd9\u4e24\u79cd\u8010\u836f\u673a\u5236\u5f15\u53d1\u7684B-NHL\uff0c\u5b89\u5168\u6027\u53ca\u8010\u53d7\u6027\u826f\u597d\uff0c\u5e76\u5728\u591a\u79cdB-NHL\u4e9a\u578b\u4e2d\u663e\u793a\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\u3002 \u5173\u4e8eDZD6008 DZD6008\u662f\u4e00\u6b3e\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5168\u65b0\u7684\u3001\u9ad8\u9009\u62e9\u6027\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\uff0c\u53ef\u5b8c\u5168\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u80fd\u6709\u6548\u6291\u5236\u591a\u79cdEGFR\u7a81\u53d8\u7ec6\u80de\u53ca\u80bf\u7624\u52a8\u7269\u6a21\u578b\u7684\u751f\u957f\u3002\u5f53\u524d\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09EGFR TKI\u8010\u836f\u673a\u5236\u672a\u660e\uff0c\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\u3002\u540c\u65f6\uff0c\u8111\u8f6c\u79fb\u662f\u5bfc\u81f4\u75be\u75c5\u8fdb\u5c55\u53ca\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c23%-30%\u7684EGFR\u7a81\u53d8NSCLC\u60a3\u8005\u5728\u521d\u6b21\u8bca\u65ad\u65f6\u5373\u5b58\u5728\u8111\u8f6c\u79fb\uff0c\u8bca\u65ad\u540e3\u5e74\u5185\u8111\u8f6c\u79fb\u7684\u98ce\u9669\u53ef\u80fd\u589e\u81f329.4%-60.3%\u3002 \u76ee\u524d\uff0c\u9488\u5bf9\u4e09\u4ee3EGFR TKI\u8010\u836fNSCLC\u7684\u73b0\u6709\u6cbb\u7597\u624b\u6bb5\u7684\u4e34\u5e8a\u83b7\u76ca\u6709\u9650\uff0cDZD6008\u6709\u671b\u586b\u8865\u8be5\u9886\u57df\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002DZD6008\u5728\u5df2\u6709\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5b8c\u5168\u9a8c\u8bc1\u4e86\u8be5\u5206\u5b50\u7684\u8bbe\u8ba1\u7406\u5ff5\uff0c\u5728\u4e09\u4ee3EGFR TKI\u548c\u591a\u7ebf\u6cbb\u7597\u5931\u8d25\u53ca\u8111\u8f6c\u79fb\u7684\u75c5\u4eba\u4e2d\u663e\u793a\u4f18\u5f02\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002 \u5173\u4e8e\u8fea\u54f2\u533b\u836f \u8fea\u54f2\u533b\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a688192.SH\uff09\u662f\u4e00\u5bb6\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u6076\u6027\u80bf\u7624\u3001\u514d\u75ab\u6027\u75be\u75c5\u9886\u57df\u521b\u65b0\u7597\u6cd5\u7684\u7814\u7a76\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u516c\u53f8\u575a\u6301\u6e90\u5934\u521b\u65b0\u7684\u7814\u53d1\u7406\u5ff5\uff0c\u4ee5\u63a8\u51fa\u5168\u7403\u9996\u521b\u836f\u7269\uff08First-in-class\uff09\u548c\u5177\u6709\u7a81\u7834\u6027\u6f5c\u529b\u7684\u6cbb\u7597\u65b9\u6cd5\u4e3a\u76ee\u6807\uff0c\u65e8\u5728\u586b\u8865\u5168\u7403\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u57fa\u4e8e\u884c\u4e1a\u9886\u5148\u7684\u8f6c\u5316\u79d1\u5b66\u548c\u65b0\u836f\u5206\u5b50\u8bbe\u8ba1\u4e0e\u7b5b\u9009\u6280\u672f\u5e73\u53f0\uff0c\u516c\u53f8\u5df2\u5efa\u7acb\u4e86\u4e03\u6b3e\u5177\u5907\u5168\u7403\u7ade\u4e89\u529b\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d\u4e24\u5927\u5904\u4e8e\u5168\u7403\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u7684\u9886\u5148\u4ea7\u54c1\uff0c\u5747\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u5173\u6ce8\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a\u8fea\u54f2Dizal\uff0c\u6216\u8bbf\u95eehttps:\/\/www.dizalpharma.com\u3002 \u524d\u77bb\u6027\u58f0\u660e \u672c\u65b0\u95fb\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u4f1a\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u8fd9\u4e9b\u8868\u8ff0\u672c\u8d28\u4e0a\u5177\u6709\u76f8\u5f53\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u3002\u5728\u4f7f\u7528&#8221;\u9884\u671f&#8221;\u3001&#8221;\u76f8\u4fe1&#8221;\u3001&#8221;\u9884\u6d4b&#8221;\u3001&#8221;\u671f\u671b&#8221;\u3001&#8221;\u6253\u7b97&#8221;\u3001&#8221;\u6709\u671b&#8221;\u53ca\u5176\u4ed6\u7c7b\u4f3c\u8bcd\u8bed\u8fdb\u884c\u8868\u8ff0\u65f6\uff0c\u51e1\u4e0e\u672c\u516c\u53f8\u6709\u5173\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c5e\u524d\u77bb\u6027\u8868\u8ff0\u3002 \u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u4e8e\u672c\u516c\u53f8\u7ba1\u7406\u5c42\u5728\u505a\u51fa\u8868\u8ff0\u65f6\u5bf9\u672a\u6765\u4e8b\u52a1\u7684\u73b0\u6709\u770b\u6cd5\u3001\u5047\u8bbe\u3001\u671f\u671b\u3001\u4f30\u8ba1\u3001\u9884\u6d4b\u548c\u7406\u89e3\u3002\u8fd9\u4e9b\u8868\u8ff0\u5e76\u975e\u5bf9\u672a\u6765\u53d1\u5c55\u7684\u4fdd\u8bc1\uff0c\u4f1a\u53d7\u5230\u98ce\u9669\u3001\u4e0d\u786e\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u8303\u56f4\uff0c\u96be\u4ee5\u9884\u8ba1\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u4eec\u7684\u4e1a\u52a1\u3001\u7ade\u4e89\u73af\u5883\u3001\u653f\u6cbb\u3001\u7ecf\u6d4e\u3001\u6cd5\u5f8b\u548c\u793e\u4f1a\u60c5\u51b5\u7684\u672a\u6765\u53d8\u5316\u53ca\u53d1\u5c55\u7684\u5f71\u54cd\uff0c\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4f1a\u4e0e\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8d44\u6599\u6709\u8f83\u5927\u5dee\u522b\u3002 \u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u5458\u6982\u4e0d\u627f\u62c5\uff08a\uff09\u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7f51\u7ad9\u6240\u8f7d\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u4e49\u52a1\uff1b\u53ca\uff08b\uff09\u00a0\u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5b9e\u73b0\u6216\u53d8\u6210\u4e0d\u6b63\u786e\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8d23\u4efb\u3002 \u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8bf7\u8054\u7cfb\u6295\u8d44\u8005\u5173\u7cfb\uff1air@dizalpharma.com\u00a0\u00a0\u5546\u52a1\u5408\u4f5c\uff1abd@dizalpharma.com\u00a0 \u00a0\u5a92\u4f53\u8054\u7edc\uff1apr@dizalpharma.com\u00a0 SOURCE \u8fea\u54f2\u533b\u836f","og_url":"https:\/\/moneycompass.com.my\/cn\/\u8fea\u54f2\u533b\u836f\u95ea\u8000asco\uff0cdzd8586\u3001dzd6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\/","og_site_name":"Money Compass CN","article_published_time":"2025-05-23T08:04:00+00:00","og_image":[{"width":144,"height":81,"url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/","url":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/","name":"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf - Money Compass CN","isPartOf":{"@id":"https:\/\/moneycompass.com.my\/cn\/#website"},"primaryImageOfPage":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage"},"image":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage"},"thumbnailUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg","datePublished":"2025-05-23T08:04:00+00:00","dateModified":"2025-05-23T08:04:00+00:00","author":{"@id":""},"breadcrumb":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#primaryimage","url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg","contentUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/05\/1-7I4gdp.jpeg","width":144,"height":81},{"@type":"BreadcrumbList","@id":"https:\/\/moneycompass.com.my\/cn\/%e8%bf%aa%e5%93%b2%e5%8c%bb%e8%8d%af%e9%97%aa%e8%80%80asco%ef%bc%8cdzd8586%e3%80%81dzd6008%e6%9e%84%e7%ad%91%e8%a1%80%e6%b6%b2%e7%98%a4%e4%b8%8e%e8%82%ba%e7%99%8c%e9%a2%86%e5%9f%9f%e5%85%a8%e7%90%83\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/moneycompass.com.my\/cn\/"},{"@type":"ListItem","position":2,"name":"\u8fea\u54f2\u533b\u836f\u95ea\u8000ASCO\uff0cDZD8586\u3001DZD6008\u6784\u7b51\u8840\u6db2\u7624\u4e0e\u80ba\u764c\u9886\u57df\u5168\u7403\u7ade\u4e89\u65b0\u4f18\u52bf"}]},{"@type":"WebSite","@id":"https:\/\/moneycompass.com.my\/cn\/#website","url":"https:\/\/moneycompass.com.my\/cn\/","name":"Money Compass CN","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/11513"}],"collection":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/comments?post=11513"}],"version-history":[{"count":0,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/11513\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media\/11514"}],"wp:attachment":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media?parent=11513"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/categories?post=11513"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/tags?post=11513"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}