{"id":12486,"date":"2025-06-16T06:38:00","date_gmt":"2025-06-16T06:38:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/"},"modified":"2025-06-16T06:38:00","modified_gmt":"2025-06-16T06:38:00","slug":"%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/","title":{"rendered":"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03"},"content":{"rendered":"<p><span class=\"legendSpanClass\">\u5929\u6d25<\/span><span class=\"legendSpanClass\">2025\u5e746\u670816\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u5408\u6e90\u751f\u7269CAR-T\u521b\u65b0\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u2014\u2014\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe<span>\u00ae<\/span>\uff09\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u7cbe\u5f69\u4eae\u76f82025\u5e74ASCO\u548cEHA\u5927\u4f1a\uff0c\u8fd9\u662f\u4e2d\u56fd\u9996\u4e2a\u767d\u8840\u75c5CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u9996\u6b21\u62a5\u9053\u3002\u4ee5\u58c1\u62a5\uff08ASCO \u58c1\u62a5\u6458\u8981\u53f7\uff1a6529\uff1bEHA \u58c1\u62a5\u6458\u8981\u53f7\uff1aPF379\uff09\u7684\u5f62\u5f0f\u5728\u4f1a\u4e0a\u53d1\u5e03\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<p><a href=\"https:\/\/mma.prnewswire.com\/media\/2711332\/image_5033248_15972886.html\" target=\"_blank\" rel=\"noopener\"><\/a><\/p>\n<\/div>\n<p>\u622a\u81f32025\u5e744\u670824\u65e5\uff0c164\u4f8b\u60a3\u8005\u8fdb\u884c\u4e86\u767d\u7ec6\u80de\u5355\u91c7\uff0c97\u4f8b\u60a3\u8005\u540e\u7eed\u63a5\u53d7\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\uff0c\u5e76\u83b7\u5f97\u53ef\u8bc4\u4f30\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7ed3\u679c\u3002<\/p>\n<p>\u7a81\u7834\u6027\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u548c\u957f\u671f\u751f\u5b58\u7387\uff1a\u6570\u636e\u622a\u81f32025\u5e744\u670830\u65e5\uff0c\u4e2d\u4f4d\u968f\u8bbf6.2\u4e2a\u6708\uff0c3\u4e2a\u6708\u5185ORR\u4e3a92.8%\uff0c3\u4e2a\u6708\u5185\u7f13\u89e3\u60a3\u8005\u7684\u5fae\u5c0f\u6b8b\u7559\u75c5\uff08MRD\uff09\u9634\u6027\u7387\u8fbe100%\u3002\u4e2d\u4f4d\u6301\u7eed\u7f13\u89e3\u65f6\u95f4\uff08DOR\uff09\u3001\u603b\u751f\u5b58\u671f\uff08OS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08RFS\uff09\u5747\u5c1a\u672a\u8fbe\u5230\uff0c\u9884\u4f30\u6240\u6709\u60a3\u80051\u5e74\u7684OS\u7387\u9ad8\u8fbe90%\u3002<\/p>\n<p>\u5353\u8d8a\u7684\u5b89\u5168\u6027\uff1a\u5728\u672c\u7814\u7a76\u4e2d\uff0c3\u53ca\u6216\u4ee5\u4e0a\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7efc\u5408\u5f81\uff08CRS\uff09\u548c\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u76f8\u5173\u795e\u7ecf\u6bd2\u6027\u7efc\u5408\u5f81\uff08ICANS\uff09\u7684\u53d1\u751f\u7387\u5747\u4e3a2.1%\u3002\u672a\u51fa\u73b0\u56e0CRS\u6216ICANS\u5bfc\u81f4\u7684\u6b7b\u4ea1\u3002<\/p>\n<p>\u5408\u6e90\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u5415\u7490\u7490\u535a\u58eb\u5f3a\u8c03\uff1a&#8221;\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe<span>\u00ae<\/span>\uff09\u662f\u6211\u56fd\u81ea\u4e3b\u7814\u53d1\u7684CAR-T\u7ec6\u80de\u4ea7\u54c1\uff0c\u4f9d\u6258\u4e8e\u5176\u72ec\u7279\u7684CD19 scFv\u5f39\u5934\u3001CAR-T\u7ed3\u6784\u548c\u5de5\u827a\u8bbe\u8ba1\uff0c\u53ef\u7cbe\u51c6\u8bc6\u522b\u9776\u5411\u80bf\u7624\u7ec6\u80de\uff0c\u5177\u5907\u9ad8\u6548\u4f4e\u6bd2\u3001\u4e00\u6b21\u8f93\u6ce8\uff0c\u6301\u7eed\u6709\u6548\u7684\u7279\u70b9\uff0c\u4e3a\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u63d0\u4f9b\u4e86\u7a81\u7834\u6027\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u672c\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5177\u5907&#8221;\u9ad8\u7f13\u89e3\u3001\u6301\u7eed\u7f13\u89e3\u3001\u5b89\u5168\u53ef\u63a7&#8221;\u7684\u4e34\u5e8a\u4f18\u52bf\u3002\u6b64\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7684\u5e94\u7528\u9010\u6b65\u524d\u79fb\uff0c\u65e2\u63d0\u9ad8\u4e86CAR-T\u7ec6\u80de\u6cbb\u7597\u7684\u7597\u6548\uff0c\u540c\u65f6\u53c8\u8fdb\u4e00\u6b65\u964d\u4f4e\u4e86CRS\u53caICANS\u7b49CAR-T\u7ec6\u80de\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u3002\u975e\u5e38\u6709\u5e78\u80fd\u591f\u57282025\u5e74ASCO\u53caEHA\u8fd9\u6837\u7684\u56fd\u9645\u9876\u7ea7\u5b66\u672f\u4f1a\u8bae\u4e0a\u5c55\u793a\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6700\u65b0\u7684\u7814\u7a76\u6210\u679c\u3002\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5728\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\u5353\u8d8a\u7597\u6548\u548c\u5b89\u5168\u6027\u6570\u636e\u7684\u4eae\u773c\u8868\u73b0\uff0c\u7a81\u663e\u4e86\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u7684\u5353\u8d8a\u5b9e\u529b\uff0c\u4e5f\u7ed9\u4e86\u516c\u53f8\u66f4\u5927\u7684\u4fe1\u5fc3\u548c\u52a8\u529b\u4e13\u6ce8\u4e8e\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u7684\u4ea7\u54c1\u7814\u53d1\u3002\u5408\u6e90\u751f\u7269\u5c06\u5728\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u6301\u7eed\u521b\u65b0\uff0c\u4e0d\u65ad\u53d6\u5f97\u65b0\u7684\u7a81\u7834\uff0c\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u4f18\u8d28\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u4e3a\u66f4\u591a\u9971\u53d7\u75be\u75c5\u6298\u78e8\u7684\u60a3\u8005\u521b\u9020\u65b0\u751f\u548c\u9ad8\u8d28\u91cf\u7684\u751f\u6d3b\u3002&#8221;<\/p>\n<p>###<\/p>\n<p>\u5173\u4e8e\u5408\u6e90\u751f\u7269\uff1a<\/p>\n<p>\u5408\u6e90\u751f\u7269\u521b\u7acb\u4e8e2018\u5e746\u6708\uff0c\u5df2\u6210\u957f\u4e3a\u4e2d\u56fd\u7ec6\u80de\u836f\u7269\u4ea7\u4e1a\u81ea\u4e3b\u521b\u65b0\u7684\u5f15\u9886\u8005\uff0c\u81f4\u529b\u4e8e\u6210\u4e3a\u5168\u7403\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u521b\u65b0\u6280\u672f\u9a71\u52a8\u7684\u65b0\u4e00\u4ee3\u751f\u7269\u533b\u836f\u4f01\u4e1a\u3002\u00a0 \u516c\u53f8\u9996\u4e2a\u6838\u5fc3\u4ea7\u54c1\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff09\u4e8e2023\u5e7411\u6708\u6b63\u5f0f\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u662f\u4e2d\u56fd\u767d\u8840\u75c5\u6cbb\u7597\u9886\u57df\u9996\u4e2aCAR-T\u836f\u7269\uff0c\u4e5f\u662f\u4e2d\u56fd\u5168\u81ea\u4e3b\u521b\u65b0\u7684\u9996\u4e2aCD19 CAR-T\u836f\u7269\u3002\u516c\u53f8\u6df1\u5ea6\u5408\u4f5c\u56fd\u5bb6\u4e00\u6d41\u9662\u6240\uff0c\u6784\u5efa\u4e86\u4ee5CAR\u6280\u672f\u5e73\u53f0\u3001\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5e73\u53f0\u7b49\u4e3a\u6838\u5fc3\u7684\u56fd\u9645\u5316\u65b0\u836f\u7814\u53d1\u4f53\u7cfb\uff0c\u62e5\u6709\u8986\u76d6\u8840\u6db2\u80bf\u7624\u3001\u5b9e\u4f53\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7b49\u75be\u75c5\u9886\u57df\u768410\u4f59\u79cd\u7ba1\u7ebf\u4ea7\u54c1\u5728\u7814\u3002\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff0cInaticabtagene Autoleucel Injection\uff09\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u9776\u5411CD19\u7684CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u62e5\u6709\u5168\u7403\u72ec\u7279\u7684CD19 scFv\uff08HI19a\uff09\u7ed3\u6784\u548c\u56fd\u9645\u9886\u5148\u7684\u751f\u4ea7\u5236\u9020\u5de5\u827a\uff0c\u5148\u540e\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e09\u9879\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\uff08IND\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u3001\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u4fb5\u88ad\u6027B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u6cbb\u7597\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u590d\u53d1\u6216\u96be\u6cbbB\u7ec6\u80de\u578b\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u5e76\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3&#8221;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&#8221;\u8ba4\u5b9a\u548c\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan Drug Designation, ODD\uff09\u30022022\u5e7412\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6b63\u5f0f\u53d7\u7406\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\u6210\u4ebar\/r B-ALL\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u5e76\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u30022023\u5e743\u6708\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7528\u4e8e\u6cbb\u7597\u6210\u4ebar\/r B-ALL IND\u7533\u8bf7\u4e5f\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08U.S.FDA\uff09\u8bb8\u53ef\u30022023\u5e7411\u6708\uff0c\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff09\u6b63\u5f0f\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u516c\u53f8\u575a\u6301\u4ee5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u4e3a\u5bfc\u5411\uff0c\u901a\u8fc7\u4e25\u683c\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u4e3a\u60a3\u8005\u6253\u9020\u5b89\u5168\u3001\u9ad8\u6548\u3001\u53ef\u53ca\u7684\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u3002\u516c\u53f8\u5177\u6709\u4e16\u754c\u4e00\u6d41\u7814\u53d1\u6280\u672f\u5e73\u53f0\uff0c\u5de5\u827a\u5f00\u53d1\u5e73\u53f0\uff0c\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u4ee5\u53ca\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\uff0c\u5e76\u4e8e2021\u5e746\u6708\u83b7\u5f97\u5929\u6d25\u5e02\u9996\u5f20\u7ec6\u80de\u836f\u7269\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b\u3002\u516c\u53f8\u62e5\u6709\u591a\u9879\u53d1\u660e\u4e13\u5229\uff0c\u5165\u9009\u56fd\u5bb6\u79d1\u6280\u90e8\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u9879\u76ee\u5373&#8221;\u79d1\u6280\u52a9\u529b\u7ecf\u6d4e2020\u91cd\u70b9\u4e13\u9879\u9879\u76ee&#8221;\uff0c\u83b7&#8221;\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u4f18\u52bf\u4f01\u4e1a&#8221;\u79f0\u53f7\u3001&#8221;\u5929\u6d25\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u8ba4\u5b9a&#8221;\u7b49\u3002<\/p>\n<p>\u00a0<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>SOURCE  \u5408\u6e90\u751f\u7269\u79d1\u6280\uff08\u5929\u6d25\uff09\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5929\u6d252025\u5e746\u670816\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u5408\u6e90\u751f\u7269CAR-T\u521b\u65b0\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u2014\u2014\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u7cbe\u5f69\u4eae\u76f82025\u5e74ASCO\u548cEHA\u5927\u4f1a\uff0c\u8fd9\u662f\u4e2d\u56fd\u9996\u4e2a\u767d\u8840\u75c5CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u9996\u6b21\u62a5\u9053\u3002\u4ee5\u58c1\u62a5\uff08ASCO \u58c1\u62a5\u6458\u8981\u53f7\uff1a6529\uff1bEHA \u58c1\u62a5\u6458\u8981\u53f7\uff1aPF379\uff09\u7684\u5f62\u5f0f\u5728\u4f1a\u4e0a\u53d1\u5e03\u3002 \u622a\u81f32025\u5e744\u670824\u65e5\uff0c164\u4f8b\u60a3\u8005\u8fdb\u884c\u4e86\u767d\u7ec6\u80de\u5355\u91c7\uff0c97\u4f8b\u60a3\u8005\u540e\u7eed\u63a5\u53d7\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\uff0c\u5e76\u83b7\u5f97\u53ef\u8bc4\u4f30\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7ed3\u679c\u3002 \u7a81\u7834\u6027\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u548c\u957f\u671f\u751f\u5b58\u7387\uff1a\u6570\u636e\u622a\u81f32025\u5e744\u670830\u65e5\uff0c\u4e2d\u4f4d\u968f\u8bbf6.2\u4e2a\u6708\uff0c3\u4e2a\u6708\u5185ORR\u4e3a92.8%\uff0c3\u4e2a\u6708\u5185\u7f13\u89e3\u60a3\u8005\u7684\u5fae\u5c0f\u6b8b\u7559\u75c5\uff08MRD\uff09\u9634\u6027\u7387\u8fbe100%\u3002\u4e2d\u4f4d\u6301\u7eed\u7f13\u89e3\u65f6\u95f4\uff08DOR\uff09\u3001\u603b\u751f\u5b58\u671f\uff08OS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08RFS\uff09\u5747\u5c1a\u672a\u8fbe\u5230\uff0c\u9884\u4f30\u6240\u6709\u60a3\u80051\u5e74\u7684OS\u7387\u9ad8\u8fbe90%\u3002 \u5353\u8d8a\u7684\u5b89\u5168\u6027\uff1a\u5728\u672c\u7814\u7a76\u4e2d\uff0c3\u53ca\u6216\u4ee5\u4e0a\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7efc\u5408\u5f81\uff08CRS\uff09\u548c\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u76f8\u5173\u795e\u7ecf\u6bd2\u6027\u7efc\u5408\u5f81\uff08ICANS\uff09\u7684\u53d1\u751f\u7387\u5747\u4e3a2.1%\u3002\u672a\u51fa\u73b0\u56e0CRS\u6216ICANS\u5bfc\u81f4\u7684\u6b7b\u4ea1\u3002 \u5408\u6e90\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u5415\u7490\u7490\u535a\u58eb\u5f3a\u8c03\uff1a&#8221;\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u662f\u6211\u56fd\u81ea\u4e3b\u7814\u53d1\u7684CAR-T\u7ec6\u80de\u4ea7\u54c1\uff0c\u4f9d\u6258\u4e8e\u5176\u72ec\u7279\u7684CD19 scFv\u5f39\u5934\u3001CAR-T\u7ed3\u6784\u548c\u5de5\u827a\u8bbe\u8ba1\uff0c\u53ef\u7cbe\u51c6\u8bc6\u522b\u9776\u5411\u80bf\u7624\u7ec6\u80de\uff0c\u5177\u5907\u9ad8\u6548\u4f4e\u6bd2\u3001\u4e00\u6b21\u8f93\u6ce8\uff0c\u6301\u7eed\u6709\u6548\u7684\u7279\u70b9\uff0c\u4e3a\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u63d0\u4f9b\u4e86\u7a81\u7834\u6027\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u672c\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5177\u5907&#8221;\u9ad8\u7f13\u89e3\u3001\u6301\u7eed\u7f13\u89e3\u3001\u5b89\u5168\u53ef\u63a7&#8221;\u7684\u4e34\u5e8a\u4f18\u52bf\u3002\u6b64\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7684\u5e94\u7528\u9010\u6b65\u524d\u79fb\uff0c\u65e2\u63d0\u9ad8\u4e86CAR-T\u7ec6\u80de\u6cbb\u7597\u7684\u7597\u6548\uff0c\u540c\u65f6\u53c8\u8fdb\u4e00\u6b65\u964d\u4f4e\u4e86CRS\u53caICANS\u7b49CAR-T\u7ec6\u80de\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u3002\u975e\u5e38\u6709\u5e78\u80fd\u591f\u57282025\u5e74ASCO\u53caEHA\u8fd9\u6837\u7684\u56fd\u9645\u9876\u7ea7\u5b66\u672f\u4f1a\u8bae\u4e0a\u5c55\u793a\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6700\u65b0\u7684\u7814\u7a76\u6210\u679c\u3002\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5728\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\u5353\u8d8a\u7597\u6548\u548c\u5b89\u5168\u6027\u6570\u636e\u7684\u4eae\u773c\u8868\u73b0\uff0c\u7a81\u663e\u4e86\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u7684\u5353\u8d8a\u5b9e\u529b\uff0c\u4e5f\u7ed9\u4e86\u516c\u53f8\u66f4\u5927\u7684\u4fe1\u5fc3\u548c\u52a8\u529b\u4e13\u6ce8\u4e8e\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u7684\u4ea7\u54c1\u7814\u53d1\u3002\u5408\u6e90\u751f\u7269\u5c06\u5728\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u6301\u7eed\u521b\u65b0\uff0c\u4e0d\u65ad\u53d6\u5f97\u65b0\u7684\u7a81\u7834\uff0c\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u4f18\u8d28\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u4e3a\u66f4\u591a\u9971\u53d7\u75be\u75c5\u6298\u78e8\u7684\u60a3\u8005\u521b\u9020\u65b0\u751f\u548c\u9ad8\u8d28\u91cf\u7684\u751f\u6d3b\u3002&#8221; ### \u5173\u4e8e\u5408\u6e90\u751f\u7269\uff1a \u5408\u6e90\u751f\u7269\u521b\u7acb\u4e8e2018\u5e746\u6708\uff0c\u5df2\u6210\u957f\u4e3a\u4e2d\u56fd\u7ec6\u80de\u836f\u7269\u4ea7\u4e1a\u81ea\u4e3b\u521b\u65b0\u7684\u5f15\u9886\u8005\uff0c\u81f4\u529b\u4e8e\u6210\u4e3a\u5168\u7403\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u521b\u65b0\u6280\u672f\u9a71\u52a8\u7684\u65b0\u4e00\u4ee3\u751f\u7269\u533b\u836f\u4f01\u4e1a\u3002\u00a0 \u516c\u53f8\u9996\u4e2a\u6838\u5fc3\u4ea7\u54c1\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff09\u4e8e2023\u5e7411\u6708\u6b63\u5f0f\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u662f\u4e2d\u56fd\u767d\u8840\u75c5\u6cbb\u7597\u9886\u57df\u9996\u4e2aCAR-T\u836f\u7269\uff0c\u4e5f\u662f\u4e2d\u56fd\u5168\u81ea\u4e3b\u521b\u65b0\u7684\u9996\u4e2aCD19 CAR-T\u836f\u7269\u3002\u516c\u53f8\u6df1\u5ea6\u5408\u4f5c\u56fd\u5bb6\u4e00\u6d41\u9662\u6240\uff0c\u6784\u5efa\u4e86\u4ee5CAR\u6280\u672f\u5e73\u53f0\u3001\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5e73\u53f0\u7b49\u4e3a\u6838\u5fc3\u7684\u56fd\u9645\u5316\u65b0\u836f\u7814\u53d1\u4f53\u7cfb\uff0c\u62e5\u6709\u8986\u76d6\u8840\u6db2\u80bf\u7624\u3001\u5b9e\u4f53\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7b49\u75be\u75c5\u9886\u57df\u768410\u4f59\u79cd\u7ba1\u7ebf\u4ea7\u54c1\u5728\u7814\u3002\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff0cInaticabtagene Autoleucel Injection\uff09\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u9776\u5411CD19\u7684CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u62e5\u6709\u5168\u7403\u72ec\u7279\u7684CD19 scFv\uff08HI19a\uff09\u7ed3\u6784\u548c\u56fd\u9645\u9886\u5148\u7684\u751f\u4ea7\u5236\u9020\u5de5\u827a\uff0c\u5148\u540e\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e09\u9879\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\uff08IND\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u3001\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u4fb5\u88ad\u6027B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u6cbb\u7597\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u590d\u53d1\u6216\u96be\u6cbbB\u7ec6\u80de\u578b\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u5e76\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3&#8221;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&#8221;\u8ba4\u5b9a\u548c\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan Drug Designation, ODD\uff09\u30022022\u5e7412\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6b63\u5f0f\u53d7\u7406\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\u6210\u4ebar\/r B-ALL\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u5e76\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u30022023\u5e743\u6708\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7528\u4e8e\u6cbb\u7597\u6210\u4ebar\/r B-ALL IND\u7533\u8bf7\u4e5f\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08U.S.FDA\uff09\u8bb8\u53ef\u30022023\u5e7411\u6708\uff0c\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff09\u6b63\u5f0f\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u516c\u53f8\u575a\u6301\u4ee5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u4e3a\u5bfc\u5411\uff0c\u901a\u8fc7\u4e25\u683c\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u4e3a\u60a3\u8005\u6253\u9020\u5b89\u5168\u3001\u9ad8\u6548\u3001\u53ef\u53ca\u7684\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u3002\u516c\u53f8\u5177\u6709\u4e16\u754c\u4e00\u6d41\u7814\u53d1\u6280\u672f\u5e73\u53f0\uff0c\u5de5\u827a\u5f00\u53d1\u5e73\u53f0\uff0c\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u4ee5\u53ca\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\uff0c\u5e76\u4e8e2021\u5e746\u6708\u83b7\u5f97\u5929\u6d25\u5e02\u9996\u5f20\u7ec6\u80de\u836f\u7269\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b\u3002\u516c\u53f8\u62e5\u6709\u591a\u9879\u53d1\u660e\u4e13\u5229\uff0c\u5165\u9009\u56fd\u5bb6\u79d1\u6280\u90e8\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u9879\u76ee\u5373&#8221;\u79d1\u6280\u52a9\u529b\u7ecf\u6d4e2020\u91cd\u70b9\u4e13\u9879\u9879\u76ee&#8221;\uff0c\u83b7&#8221;\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u4f18\u52bf\u4f01\u4e1a&#8221;\u79f0\u53f7\u3001&#8221;\u5929\u6d25\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u8ba4\u5b9a&#8221;\u7b49\u3002 \u00a0 SOURCE \u5408\u6e90\u751f\u7269\u79d1\u6280\uff08\u5929\u6d25\uff09\u6709\u9650\u516c\u53f8<\/p>\n","protected":false},"author":0,"featured_media":12487,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-12486","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u5408\u6e90\u751f\u7269car-t\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"\u5929\u6d252025\u5e746\u670816\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u5408\u6e90\u751f\u7269CAR-T\u521b\u65b0\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u2014\u2014\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u7cbe\u5f69\u4eae\u76f82025\u5e74ASCO\u548cEHA\u5927\u4f1a\uff0c\u8fd9\u662f\u4e2d\u56fd\u9996\u4e2a\u767d\u8840\u75c5CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u9996\u6b21\u62a5\u9053\u3002\u4ee5\u58c1\u62a5\uff08ASCO \u58c1\u62a5\u6458\u8981\u53f7\uff1a6529\uff1bEHA \u58c1\u62a5\u6458\u8981\u53f7\uff1aPF379\uff09\u7684\u5f62\u5f0f\u5728\u4f1a\u4e0a\u53d1\u5e03\u3002 \u622a\u81f32025\u5e744\u670824\u65e5\uff0c164\u4f8b\u60a3\u8005\u8fdb\u884c\u4e86\u767d\u7ec6\u80de\u5355\u91c7\uff0c97\u4f8b\u60a3\u8005\u540e\u7eed\u63a5\u53d7\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\uff0c\u5e76\u83b7\u5f97\u53ef\u8bc4\u4f30\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7ed3\u679c\u3002 \u7a81\u7834\u6027\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u548c\u957f\u671f\u751f\u5b58\u7387\uff1a\u6570\u636e\u622a\u81f32025\u5e744\u670830\u65e5\uff0c\u4e2d\u4f4d\u968f\u8bbf6.2\u4e2a\u6708\uff0c3\u4e2a\u6708\u5185ORR\u4e3a92.8%\uff0c3\u4e2a\u6708\u5185\u7f13\u89e3\u60a3\u8005\u7684\u5fae\u5c0f\u6b8b\u7559\u75c5\uff08MRD\uff09\u9634\u6027\u7387\u8fbe100%\u3002\u4e2d\u4f4d\u6301\u7eed\u7f13\u89e3\u65f6\u95f4\uff08DOR\uff09\u3001\u603b\u751f\u5b58\u671f\uff08OS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08RFS\uff09\u5747\u5c1a\u672a\u8fbe\u5230\uff0c\u9884\u4f30\u6240\u6709\u60a3\u80051\u5e74\u7684OS\u7387\u9ad8\u8fbe90%\u3002 \u5353\u8d8a\u7684\u5b89\u5168\u6027\uff1a\u5728\u672c\u7814\u7a76\u4e2d\uff0c3\u53ca\u6216\u4ee5\u4e0a\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7efc\u5408\u5f81\uff08CRS\uff09\u548c\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u76f8\u5173\u795e\u7ecf\u6bd2\u6027\u7efc\u5408\u5f81\uff08ICANS\uff09\u7684\u53d1\u751f\u7387\u5747\u4e3a2.1%\u3002\u672a\u51fa\u73b0\u56e0CRS\u6216ICANS\u5bfc\u81f4\u7684\u6b7b\u4ea1\u3002 \u5408\u6e90\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u5415\u7490\u7490\u535a\u58eb\u5f3a\u8c03\uff1a&#8221;\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u662f\u6211\u56fd\u81ea\u4e3b\u7814\u53d1\u7684CAR-T\u7ec6\u80de\u4ea7\u54c1\uff0c\u4f9d\u6258\u4e8e\u5176\u72ec\u7279\u7684CD19 scFv\u5f39\u5934\u3001CAR-T\u7ed3\u6784\u548c\u5de5\u827a\u8bbe\u8ba1\uff0c\u53ef\u7cbe\u51c6\u8bc6\u522b\u9776\u5411\u80bf\u7624\u7ec6\u80de\uff0c\u5177\u5907\u9ad8\u6548\u4f4e\u6bd2\u3001\u4e00\u6b21\u8f93\u6ce8\uff0c\u6301\u7eed\u6709\u6548\u7684\u7279\u70b9\uff0c\u4e3a\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u63d0\u4f9b\u4e86\u7a81\u7834\u6027\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u672c\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5177\u5907&#8221;\u9ad8\u7f13\u89e3\u3001\u6301\u7eed\u7f13\u89e3\u3001\u5b89\u5168\u53ef\u63a7&#8221;\u7684\u4e34\u5e8a\u4f18\u52bf\u3002\u6b64\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7684\u5e94\u7528\u9010\u6b65\u524d\u79fb\uff0c\u65e2\u63d0\u9ad8\u4e86CAR-T\u7ec6\u80de\u6cbb\u7597\u7684\u7597\u6548\uff0c\u540c\u65f6\u53c8\u8fdb\u4e00\u6b65\u964d\u4f4e\u4e86CRS\u53caICANS\u7b49CAR-T\u7ec6\u80de\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u3002\u975e\u5e38\u6709\u5e78\u80fd\u591f\u57282025\u5e74ASCO\u53caEHA\u8fd9\u6837\u7684\u56fd\u9645\u9876\u7ea7\u5b66\u672f\u4f1a\u8bae\u4e0a\u5c55\u793a\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6700\u65b0\u7684\u7814\u7a76\u6210\u679c\u3002\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5728\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\u5353\u8d8a\u7597\u6548\u548c\u5b89\u5168\u6027\u6570\u636e\u7684\u4eae\u773c\u8868\u73b0\uff0c\u7a81\u663e\u4e86\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u7684\u5353\u8d8a\u5b9e\u529b\uff0c\u4e5f\u7ed9\u4e86\u516c\u53f8\u66f4\u5927\u7684\u4fe1\u5fc3\u548c\u52a8\u529b\u4e13\u6ce8\u4e8e\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u7684\u4ea7\u54c1\u7814\u53d1\u3002\u5408\u6e90\u751f\u7269\u5c06\u5728\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u6301\u7eed\u521b\u65b0\uff0c\u4e0d\u65ad\u53d6\u5f97\u65b0\u7684\u7a81\u7834\uff0c\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u4f18\u8d28\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u4e3a\u66f4\u591a\u9971\u53d7\u75be\u75c5\u6298\u78e8\u7684\u60a3\u8005\u521b\u9020\u65b0\u751f\u548c\u9ad8\u8d28\u91cf\u7684\u751f\u6d3b\u3002&#8221; ### \u5173\u4e8e\u5408\u6e90\u751f\u7269\uff1a \u5408\u6e90\u751f\u7269\u521b\u7acb\u4e8e2018\u5e746\u6708\uff0c\u5df2\u6210\u957f\u4e3a\u4e2d\u56fd\u7ec6\u80de\u836f\u7269\u4ea7\u4e1a\u81ea\u4e3b\u521b\u65b0\u7684\u5f15\u9886\u8005\uff0c\u81f4\u529b\u4e8e\u6210\u4e3a\u5168\u7403\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u521b\u65b0\u6280\u672f\u9a71\u52a8\u7684\u65b0\u4e00\u4ee3\u751f\u7269\u533b\u836f\u4f01\u4e1a\u3002\u00a0 \u516c\u53f8\u9996\u4e2a\u6838\u5fc3\u4ea7\u54c1\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff09\u4e8e2023\u5e7411\u6708\u6b63\u5f0f\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u662f\u4e2d\u56fd\u767d\u8840\u75c5\u6cbb\u7597\u9886\u57df\u9996\u4e2aCAR-T\u836f\u7269\uff0c\u4e5f\u662f\u4e2d\u56fd\u5168\u81ea\u4e3b\u521b\u65b0\u7684\u9996\u4e2aCD19 CAR-T\u836f\u7269\u3002\u516c\u53f8\u6df1\u5ea6\u5408\u4f5c\u56fd\u5bb6\u4e00\u6d41\u9662\u6240\uff0c\u6784\u5efa\u4e86\u4ee5CAR\u6280\u672f\u5e73\u53f0\u3001\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5e73\u53f0\u7b49\u4e3a\u6838\u5fc3\u7684\u56fd\u9645\u5316\u65b0\u836f\u7814\u53d1\u4f53\u7cfb\uff0c\u62e5\u6709\u8986\u76d6\u8840\u6db2\u80bf\u7624\u3001\u5b9e\u4f53\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7b49\u75be\u75c5\u9886\u57df\u768410\u4f59\u79cd\u7ba1\u7ebf\u4ea7\u54c1\u5728\u7814\u3002\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff0cInaticabtagene Autoleucel Injection\uff09\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u9776\u5411CD19\u7684CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u62e5\u6709\u5168\u7403\u72ec\u7279\u7684CD19 scFv\uff08HI19a\uff09\u7ed3\u6784\u548c\u56fd\u9645\u9886\u5148\u7684\u751f\u4ea7\u5236\u9020\u5de5\u827a\uff0c\u5148\u540e\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e09\u9879\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\uff08IND\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u3001\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u4fb5\u88ad\u6027B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u6cbb\u7597\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u590d\u53d1\u6216\u96be\u6cbbB\u7ec6\u80de\u578b\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u5e76\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3&#8221;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&#8221;\u8ba4\u5b9a\u548c\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan Drug Designation, ODD\uff09\u30022022\u5e7412\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6b63\u5f0f\u53d7\u7406\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\u6210\u4ebar\/r B-ALL\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u5e76\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u30022023\u5e743\u6708\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7528\u4e8e\u6cbb\u7597\u6210\u4ebar\/r B-ALL IND\u7533\u8bf7\u4e5f\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08U.S.FDA\uff09\u8bb8\u53ef\u30022023\u5e7411\u6708\uff0c\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff09\u6b63\u5f0f\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u516c\u53f8\u575a\u6301\u4ee5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u4e3a\u5bfc\u5411\uff0c\u901a\u8fc7\u4e25\u683c\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u4e3a\u60a3\u8005\u6253\u9020\u5b89\u5168\u3001\u9ad8\u6548\u3001\u53ef\u53ca\u7684\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u3002\u516c\u53f8\u5177\u6709\u4e16\u754c\u4e00\u6d41\u7814\u53d1\u6280\u672f\u5e73\u53f0\uff0c\u5de5\u827a\u5f00\u53d1\u5e73\u53f0\uff0c\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u4ee5\u53ca\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\uff0c\u5e76\u4e8e2021\u5e746\u6708\u83b7\u5f97\u5929\u6d25\u5e02\u9996\u5f20\u7ec6\u80de\u836f\u7269\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b\u3002\u516c\u53f8\u62e5\u6709\u591a\u9879\u53d1\u660e\u4e13\u5229\uff0c\u5165\u9009\u56fd\u5bb6\u79d1\u6280\u90e8\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u9879\u76ee\u5373&#8221;\u79d1\u6280\u52a9\u529b\u7ecf\u6d4e2020\u91cd\u70b9\u4e13\u9879\u9879\u76ee&#8221;\uff0c\u83b7&#8221;\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u4f18\u52bf\u4f01\u4e1a&#8221;\u79f0\u53f7\u3001&#8221;\u5929\u6d25\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u8ba4\u5b9a&#8221;\u7b49\u3002 \u00a0 SOURCE \u5408\u6e90\u751f\u7269\u79d1\u6280\uff08\u5929\u6d25\uff09\u6709\u9650\u516c\u53f8\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u5408\u6e90\u751f\u7269car-t\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-16T06:38:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"144\" \/>\n\t<meta property=\"og:image:height\" content=\"84\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/\",\"name\":\"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN\",\"isPartOf\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg\",\"datePublished\":\"2025-06-16T06:38:00+00:00\",\"dateModified\":\"2025-06-16T06:38:00+00:00\",\"author\":{\"@id\":\"\"},\"breadcrumb\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg\",\"contentUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg\",\"width\":144,\"height\":84},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/moneycompass.com.my\/cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/\",\"name\":\"Money Compass CN\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/moneycompass.com.my\/cn\/\u5408\u6e90\u751f\u7269car-t\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\/","og_locale":"en_US","og_type":"article","og_title":"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN","og_description":"\u5929\u6d252025\u5e746\u670816\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u5408\u6e90\u751f\u7269CAR-T\u521b\u65b0\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u2014\u2014\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u7cbe\u5f69\u4eae\u76f82025\u5e74ASCO\u548cEHA\u5927\u4f1a\uff0c\u8fd9\u662f\u4e2d\u56fd\u9996\u4e2a\u767d\u8840\u75c5CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u9996\u6b21\u62a5\u9053\u3002\u4ee5\u58c1\u62a5\uff08ASCO \u58c1\u62a5\u6458\u8981\u53f7\uff1a6529\uff1bEHA \u58c1\u62a5\u6458\u8981\u53f7\uff1aPF379\uff09\u7684\u5f62\u5f0f\u5728\u4f1a\u4e0a\u53d1\u5e03\u3002 \u622a\u81f32025\u5e744\u670824\u65e5\uff0c164\u4f8b\u60a3\u8005\u8fdb\u884c\u4e86\u767d\u7ec6\u80de\u5355\u91c7\uff0c97\u4f8b\u60a3\u8005\u540e\u7eed\u63a5\u53d7\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\uff0c\u5e76\u83b7\u5f97\u53ef\u8bc4\u4f30\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7ed3\u679c\u3002 \u7a81\u7834\u6027\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u548c\u957f\u671f\u751f\u5b58\u7387\uff1a\u6570\u636e\u622a\u81f32025\u5e744\u670830\u65e5\uff0c\u4e2d\u4f4d\u968f\u8bbf6.2\u4e2a\u6708\uff0c3\u4e2a\u6708\u5185ORR\u4e3a92.8%\uff0c3\u4e2a\u6708\u5185\u7f13\u89e3\u60a3\u8005\u7684\u5fae\u5c0f\u6b8b\u7559\u75c5\uff08MRD\uff09\u9634\u6027\u7387\u8fbe100%\u3002\u4e2d\u4f4d\u6301\u7eed\u7f13\u89e3\u65f6\u95f4\uff08DOR\uff09\u3001\u603b\u751f\u5b58\u671f\uff08OS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08RFS\uff09\u5747\u5c1a\u672a\u8fbe\u5230\uff0c\u9884\u4f30\u6240\u6709\u60a3\u80051\u5e74\u7684OS\u7387\u9ad8\u8fbe90%\u3002 \u5353\u8d8a\u7684\u5b89\u5168\u6027\uff1a\u5728\u672c\u7814\u7a76\u4e2d\uff0c3\u53ca\u6216\u4ee5\u4e0a\u7684\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7efc\u5408\u5f81\uff08CRS\uff09\u548c\u514d\u75ab\u6548\u5e94\u7ec6\u80de\u76f8\u5173\u795e\u7ecf\u6bd2\u6027\u7efc\u5408\u5f81\uff08ICANS\uff09\u7684\u53d1\u751f\u7387\u5747\u4e3a2.1%\u3002\u672a\u51fa\u73b0\u56e0CRS\u6216ICANS\u5bfc\u81f4\u7684\u6b7b\u4ea1\u3002 \u5408\u6e90\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u5415\u7490\u7490\u535a\u58eb\u5f3a\u8c03\uff1a&#8221;\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff08\u5546\u54c1\u540d\uff1a\u6e90\u745e\u8fbe\u00ae\uff09\u662f\u6211\u56fd\u81ea\u4e3b\u7814\u53d1\u7684CAR-T\u7ec6\u80de\u4ea7\u54c1\uff0c\u4f9d\u6258\u4e8e\u5176\u72ec\u7279\u7684CD19 scFv\u5f39\u5934\u3001CAR-T\u7ed3\u6784\u548c\u5de5\u827a\u8bbe\u8ba1\uff0c\u53ef\u7cbe\u51c6\u8bc6\u522b\u9776\u5411\u80bf\u7624\u7ec6\u80de\uff0c\u5177\u5907\u9ad8\u6548\u4f4e\u6bd2\u3001\u4e00\u6b21\u8f93\u6ce8\uff0c\u6301\u7eed\u6709\u6548\u7684\u7279\u70b9\uff0c\u4e3a\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u63d0\u4f9b\u4e86\u7a81\u7834\u6027\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u672c\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5177\u5907&#8221;\u9ad8\u7f13\u89e3\u3001\u6301\u7eed\u7f13\u89e3\u3001\u5b89\u5168\u53ef\u63a7&#8221;\u7684\u4e34\u5e8a\u4f18\u52bf\u3002\u6b64\u6b21\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7684\u5e94\u7528\u9010\u6b65\u524d\u79fb\uff0c\u65e2\u63d0\u9ad8\u4e86CAR-T\u7ec6\u80de\u6cbb\u7597\u7684\u7597\u6548\uff0c\u540c\u65f6\u53c8\u8fdb\u4e00\u6b65\u964d\u4f4e\u4e86CRS\u53caICANS\u7b49CAR-T\u7ec6\u80de\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u3002\u975e\u5e38\u6709\u5e78\u80fd\u591f\u57282025\u5e74ASCO\u53caEHA\u8fd9\u6837\u7684\u56fd\u9645\u9876\u7ea7\u5b66\u672f\u4f1a\u8bae\u4e0a\u5c55\u793a\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6700\u65b0\u7684\u7814\u7a76\u6210\u679c\u3002\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u5728\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u4e2d\u5353\u8d8a\u7597\u6548\u548c\u5b89\u5168\u6027\u6570\u636e\u7684\u4eae\u773c\u8868\u73b0\uff0c\u7a81\u663e\u4e86\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u7684\u5353\u8d8a\u5b9e\u529b\uff0c\u4e5f\u7ed9\u4e86\u516c\u53f8\u66f4\u5927\u7684\u4fe1\u5fc3\u548c\u52a8\u529b\u4e13\u6ce8\u4e8e\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u7684\u4ea7\u54c1\u7814\u53d1\u3002\u5408\u6e90\u751f\u7269\u5c06\u5728\u7ec6\u80de\u6cbb\u7597\u9886\u57df\u6301\u7eed\u521b\u65b0\uff0c\u4e0d\u65ad\u53d6\u5f97\u65b0\u7684\u7a81\u7834\uff0c\u4e3a\u4e2d\u56fd\u53ca\u5168\u7403\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u4f18\u8d28\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u4e3a\u66f4\u591a\u9971\u53d7\u75be\u75c5\u6298\u78e8\u7684\u60a3\u8005\u521b\u9020\u65b0\u751f\u548c\u9ad8\u8d28\u91cf\u7684\u751f\u6d3b\u3002&#8221; ### \u5173\u4e8e\u5408\u6e90\u751f\u7269\uff1a \u5408\u6e90\u751f\u7269\u521b\u7acb\u4e8e2018\u5e746\u6708\uff0c\u5df2\u6210\u957f\u4e3a\u4e2d\u56fd\u7ec6\u80de\u836f\u7269\u4ea7\u4e1a\u81ea\u4e3b\u521b\u65b0\u7684\u5f15\u9886\u8005\uff0c\u81f4\u529b\u4e8e\u6210\u4e3a\u5168\u7403\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u521b\u65b0\u6280\u672f\u9a71\u52a8\u7684\u65b0\u4e00\u4ee3\u751f\u7269\u533b\u836f\u4f01\u4e1a\u3002\u00a0 \u516c\u53f8\u9996\u4e2a\u6838\u5fc3\u4ea7\u54c1\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff09\u4e8e2023\u5e7411\u6708\u6b63\u5f0f\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u662f\u4e2d\u56fd\u767d\u8840\u75c5\u6cbb\u7597\u9886\u57df\u9996\u4e2aCAR-T\u836f\u7269\uff0c\u4e5f\u662f\u4e2d\u56fd\u5168\u81ea\u4e3b\u521b\u65b0\u7684\u9996\u4e2aCD19 CAR-T\u836f\u7269\u3002\u516c\u53f8\u6df1\u5ea6\u5408\u4f5c\u56fd\u5bb6\u4e00\u6d41\u9662\u6240\uff0c\u6784\u5efa\u4e86\u4ee5CAR\u6280\u672f\u5e73\u53f0\u3001\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5e73\u53f0\u7b49\u4e3a\u6838\u5fc3\u7684\u56fd\u9645\u5316\u65b0\u836f\u7814\u53d1\u4f53\u7cfb\uff0c\u62e5\u6709\u8986\u76d6\u8840\u6db2\u80bf\u7624\u3001\u5b9e\u4f53\u80bf\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7b49\u75be\u75c5\u9886\u57df\u768410\u4f59\u79cd\u7ba1\u7ebf\u4ea7\u54c1\u5728\u7814\u3002\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff0cCNCT19\uff0cInaticabtagene Autoleucel Injection\uff09\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u9776\u5411CD19\u7684CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\uff0c\u62e5\u6709\u5168\u7403\u72ec\u7279\u7684CD19 scFv\uff08HI19a\uff09\u7ed3\u6784\u548c\u56fd\u9645\u9886\u5148\u7684\u751f\u4ea7\u5236\u9020\u5de5\u827a\uff0c\u5148\u540e\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e09\u9879\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\uff08IND\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u3001\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u4fb5\u88ad\u6027B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u548c\u6cbb\u7597\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u590d\u53d1\u6216\u96be\u6cbbB\u7ec6\u80de\u578b\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u5e76\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3&#8221;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&#8221;\u8ba4\u5b9a\u548c\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan Drug Designation, ODD\uff09\u30022022\u5e7412\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6b63\u5f0f\u53d7\u7406\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u6cbb\u7597\u6210\u4ebar\/r B-ALL\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u5e76\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u30022023\u5e743\u6708\uff0c\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u7528\u4e8e\u6cbb\u7597\u6210\u4ebar\/r B-ALL IND\u7533\u8bf7\u4e5f\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08U.S.FDA\uff09\u8bb8\u53ef\u30022023\u5e7411\u6708\uff0c\u6e90\u745e\u8fbe\u00ae\uff08\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\uff09\u6b63\u5f0f\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u516c\u53f8\u575a\u6301\u4ee5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u4e3a\u5bfc\u5411\uff0c\u901a\u8fc7\u4e25\u683c\u7684\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u751f\u4ea7\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u4e3a\u60a3\u8005\u6253\u9020\u5b89\u5168\u3001\u9ad8\u6548\u3001\u53ef\u53ca\u7684\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u3002\u516c\u53f8\u5177\u6709\u4e16\u754c\u4e00\u6d41\u7814\u53d1\u6280\u672f\u5e73\u53f0\uff0c\u5de5\u827a\u5f00\u53d1\u5e73\u53f0\uff0c\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u4ee5\u53ca\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\uff0c\u5e76\u4e8e2021\u5e746\u6708\u83b7\u5f97\u5929\u6d25\u5e02\u9996\u5f20\u7ec6\u80de\u836f\u7269\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b\u3002\u516c\u53f8\u62e5\u6709\u591a\u9879\u53d1\u660e\u4e13\u5229\uff0c\u5165\u9009\u56fd\u5bb6\u79d1\u6280\u90e8\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u9879\u76ee\u5373&#8221;\u79d1\u6280\u52a9\u529b\u7ecf\u6d4e2020\u91cd\u70b9\u4e13\u9879\u9879\u76ee&#8221;\uff0c\u83b7&#8221;\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u4f18\u52bf\u4f01\u4e1a&#8221;\u79f0\u53f7\u3001&#8221;\u5929\u6d25\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u8ba4\u5b9a&#8221;\u7b49\u3002 \u00a0 SOURCE \u5408\u6e90\u751f\u7269\u79d1\u6280\uff08\u5929\u6d25\uff09\u6709\u9650\u516c\u53f8","og_url":"https:\/\/moneycompass.com.my\/cn\/\u5408\u6e90\u751f\u7269car-t\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\/","og_site_name":"Money Compass CN","article_published_time":"2025-06-16T06:38:00+00:00","og_image":[{"width":144,"height":84,"url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/","url":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/","name":"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03 - Money Compass CN","isPartOf":{"@id":"https:\/\/moneycompass.com.my\/cn\/#website"},"primaryImageOfPage":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage"},"image":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage"},"thumbnailUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg","datePublished":"2025-06-16T06:38:00+00:00","dateModified":"2025-06-16T06:38:00+00:00","author":{"@id":""},"breadcrumb":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#primaryimage","url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg","contentUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2025\/06\/image_5033248_15972886-tZNtoI.jpeg","width":144,"height":84},{"@type":"BreadcrumbList","@id":"https:\/\/moneycompass.com.my\/cn\/%e5%90%88%e6%ba%90%e7%94%9f%e7%89%a9car-t%e4%ba%a7%e5%93%81%e7%ba%b3%e5%9f%ba%e5%a5%a5%e4%bb%91%e8%b5%9b%e6%b3%a8%e5%b0%84%e6%b6%b2%e9%a6%96%e4%b8%aa%e7%9c%9f%e5%ae%9e%e4%b8%96%e7%95%8c%e7%a0%94\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/moneycompass.com.my\/cn\/"},{"@type":"ListItem","position":2,"name":"\u5408\u6e90\u751f\u7269CAR-T\u4ea7\u54c1\u7eb3\u57fa\u5965\u4ed1\u8d5b\u6ce8\u5c04\u6db2\u9996\u4e2a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6210\u679c\u4e8e2025\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u548c\u6b27\u6d32\u8840\u6db2\u5b66\u4f1a\uff08EHA\uff09\u5e74\u4f1a\u91cd\u78c5\u53d1\u5e03"}]},{"@type":"WebSite","@id":"https:\/\/moneycompass.com.my\/cn\/#website","url":"https:\/\/moneycompass.com.my\/cn\/","name":"Money Compass CN","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/12486"}],"collection":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/comments?post=12486"}],"version-history":[{"count":0,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/12486\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media\/12487"}],"wp:attachment":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media?parent=12486"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/categories?post=12486"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/tags?post=12486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}