{"id":19219,"date":"2025-11-25T13:30:00","date_gmt":"2025-11-25T13:30:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e7%be%8e%e7%ba%b3%e9%87%8c%e5%b0%bc%e9%9b%86%e5%9b%a2%e5%ae%a3%e5%b8%83elzonris-tagraxofusp-erzs%e6%96%b0%e6%95%b0%e6%8d%ae%e5%b0%86%e5%9c%a8%e7%ac%ac67%e5%b1%8a%e7%be%8e%e5%9b%bd%e8%a1%80\/"},"modified":"2025-11-25T13:30:00","modified_gmt":"2025-11-25T13:30:00","slug":"%e7%be%8e%e7%ba%b3%e9%87%8c%e5%b0%bc%e9%9b%86%e5%9b%a2%e5%ae%a3%e5%b8%83elzonris-tagraxofusp-erzs%e6%96%b0%e6%95%b0%e6%8d%ae%e5%b0%86%e5%9c%a8%e7%ac%ac67%e5%b1%8a%e7%be%8e%e5%9b%bd%e8%a1%80","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e7%be%8e%e7%ba%b3%e9%87%8c%e5%b0%bc%e9%9b%86%e5%9b%a2%e5%ae%a3%e5%b8%83elzonris-tagraxofusp-erzs%e6%96%b0%e6%95%b0%e6%8d%ae%e5%b0%86%e5%9c%a8%e7%ac%ac67%e5%b1%8a%e7%be%8e%e5%9b%bd%e8%a1%80\/","title":{"rendered":"\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2\u5ba3\u5e03ELZONRIS \u00ae (tagraxofusp-erzs)\u65b0\u6570\u636e\u5c06\u5728\u7b2c67\u5c4a\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a\u5e74\u4f1a\u66a8\u535a\u89c8\u4f1a\u4e0a\u516c\u5e03"},"content":{"rendered":"<p>\u6570\u636e\u8de8\u8d8a\u4e94\u4efd\u6458\u8981\uff0c\u5305\u62ec\u4e24\u4efd\u53e3\u5934\u62a5\u544a\uff0c\u5176\u4e2d\u6709\u9488\u5bf9\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u60a3\u8005\u7684\u91cd\u8981\u53d1\u73b0<\/p>\n<p> BPDCN\u662f\u4e00\u79cd\u9ad8\u5ea6\u4fb5\u88ad\u6027\u7684\u5b64\u513f\u8840\u6db2\u6076\u6027\u80bf\u7624\uff0c\u4e3b\u8981\u5f71\u54cd\u76ae\u80a4\u3001\u9aa8\u9ad3\u548c\u8840\u6db2<\/p>\n<p><span class=\"legendSpanClass\">\u610f\u5927\u5229\u4f5b\u7f57\u4f26\u8428\u548c\u7ebd\u7ea6<\/span><span class=\"legendSpanClass\">2025\u5e7411\u670825\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u9886\u5148\u7684\u56fd\u9645\u5236\u836f\u548c\u8bca\u65ad\u516c\u53f8\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2(&#8220;Menarini&#8221;)\uff0c\u4ee5\u53ca\u4e13\u6ce8\u4e8e\u4e3a\u764c\u75c7\u60a3\u8005\u5e26\u6765\u53d8\u9769\u6027\u80bf\u7624\u7597\u6cd5\u7684\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2\u5168\u8d44\u5b50\u516c\u53f8Stemline Therapeutics, Inc. (&#8220;Stemline&#8221;)\uff0c\u4eca\u5929\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5c06\u572812\u67086\u65e5\u81f39\u65e5\u5728\u5965\u5170\u591a\u4e3e\u884c\u7684\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a(ASH)\u5e74\u4f1a\u4e0a\u5c55\u793a\u4e0eELZONRIS \u00ae (tagraxofusp-erzs)\u76f8\u5173\u7684\u65b0\u6570\u636e\u3002<\/p>\n<div><\/div>\n<p>\u6f14\u793a\u6587\u7a3f\u5305\u62ec\u53e3\u5934\u5f3a\u8c03\u4e09\u8054\u7597\u6cd5\u8054\u5408tagraxofusp\u3001\u963f\u624e\u80de\u82f7\u548cvenetoclax\u7684\u7ed3\u679c\uff0c\u8be5\u7597\u6cd5\u5728\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u60a3\u8005\u4e2d\u8bc1\u660e\u4e86\u7597\u6548\uff08\u9ad8\u7f13\u89e3\u7387\u548c\u6865\u63a5\u79fb\u690d\u7387\uff09\u548c\u8010\u53d7\u6027\u3002<\/p>\n<p>\u201c\u5728Menarini Stemline\uff0c\u6211\u4eec\u575a\u5b9a\u4e0d\u79fb\u5730\u81f4\u529b\u4e8e\u6539\u53d8\u96be\u4ee5\u6cbb\u7597\u7684\u764c\u75c7\u60a3\u8005\u7684\u751f\u6d3b\uff0c\u201d\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2\u9996\u5e2d\u6267\u884c\u5b98Elcin Barker Ergun\u8868\u793a\u3002\u201c\u8fd9\u4e9b\u6570\u636e\u8868\u660e\uff0ctagraxofusp\u5728BPDCN\u7684\u5355\u836f\u6cbb\u7597\u548c\u8054\u5408\u6cbb\u7597\u4e2d\u90fd\u8d77\u7740\u91cd\u8981\u4f5c\u7528\uff0c\u5e76\u4e14\u5b83\u4e5f\u6709\u6f5c\u529b\u5e2e\u52a9\u60a3\u6709\u5176\u4ed6\u4fb5\u88ad\u6027\u8840\u6db2\u6076\u6027\u80bf\u7624\u7684\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u8feb\u5207\u9700\u8981\u66f4\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6848\u3002\u201d<\/p>\n<p>\u6709\u5173Menarini Group\/Stemline Therapeutics\u5373\u5c06\u53d1\u8868\u7684\u6f14\u8bb2\u548c\u51fa\u7248\u7269\u7684\u5b8c\u6574\u8be6\u7ec6\u4fe1\u606f\uff0c\u8bf7\u53c2\u9605\u4e0b\u6587\uff1a<\/p>\n<p> 2025\u5e74\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a\uff08ASH\uff09\u5e74\u4f1a<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e3b\u8981\u4f5c\u8005 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u6807\u9898\u548c\u51fa\u7248\u7269\u7f16\u53f7 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u8bfe\u6b21\u540d\u79f0 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u6f14\u8bb2\u8be6\u60c5 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Navarro Vicente I, et al. <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 257\u540d\u60a3\u6709<br \/>\u6210\u7ea4\u7ef4\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u72b6\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u60a3\u8005\u7684\u75be\u75c5\u8868\u73b0\u548c\u514d\u75ab\u8868\u578b\u7279\u5f81\uff1a\u4e00\u9879PETHEMA\/PALG\u7814\u7a76* <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u51fa\u7248\u7269\u7f16\u53f7\uff1a218 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 618. \u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff1a <br \/>\u8bca\u65ad\u548c\u9884\u540e\u4e2d\u7684\u751f\u7269\u6807\u5fd7\u7269\u548c\u5206\u5b50\u6807\u5fd7\u7269\uff1a <br \/>\u91cd\u65b0\u5b9a\u4e49AML\uff1a\u9057\u4f20\u3001\u8868\u578b<br \/>\u548c\u57fa\u4e8e\u53cd\u5e94\u7684\u89c1\u89e3<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u53e3\u5934\u62a5\u544a <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 2025\u5e7412\u67086\u65e5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e0b\u53482:15 -\u4e0b\u53482:30 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> OCCC &#8211; W414AB <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Lane A\u7b49<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Tagraxofusp\u3001\u6c2e\u80de\u82f7\u548cvenetoclax (TAG-AZA-VEN)\u4e09\u8054\u7597\u6cd5\u5728\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u7ec6\u80de\u7624(BPDCN)\u60a3\u8005\u4e2d\u663e\u793a<br \/>\u7597\u6548\u3001\u8010\u53d7\u6027\u548c\u79fb\u690d\u6f5c\u529b\uff1a2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c* <br \/><\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u51fa\u7248\u7269\u7f16\u53f7\uff1a653 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 616. \u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff1a <br \/>\u7814\u7a76\u836f\u7269\u548c\u7ec6\u80de<br \/>\u6cbb\u7597\uff1a\u514d\u75ab\u7597\u6cd5\u548c<br \/>AML\u5316\u7597\u7ec4\u5408<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u53e3\u5934\u6f14\u793a <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 2025\u5e7412\u67087\u65e5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e0b\u53485:30 -\u4e0b\u53485:45 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0OCCC &#8211; Chapin\u5267\u9662\uff08W320\uff09 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Stein A\u7b49<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e0eVenetoclax\u76f8\u6bd4\uff0cTagraxofusp\u5728\u82bd\u80bf\u60a3\u8005\u4e2d\u7684\u751f\u5b58\u671f\u66f4\u957f<br \/>\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u72b6\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\uff1a\u771f\u5b9e\u4e16\u754c\u5206\u6790\u7ed3\u679c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u51fa\u7248\u7269\u7f16\u53f7\uff1a4612 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 908. \u7ed3\u679c\u7814\u7a76\uff1a <br \/>\u9aa8\u9ad3\u6076\u6027\u80bf\u7624\uff1a\u6d77\u62a5II <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u58c1\u62a5 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 2025\u5e7412\u67087\u65e5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e0b\u53486:00 -\u665a\u4e0a8:00 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> OCCC -\u897f\u5927\u5385B3-B4 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Wang E, et al. <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u5728\u63a5\u53d7tagraxofusp\uff08TAG\uff09\u6cbb\u7597\u7684\u6bcd\u7ec6\u80de\u6027<br \/>\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u521d\u6cbb\u60a3\u8005\u4e2d\uff0c\u5305\u62ec\u79fb\u690d\u540e\u751f\u5b58\u671f\u5728\u5185\u7684\u826f\u597d\u7ed3\u5c40\u4e0e\u57fa\u7ebf\u76ae\u80a4\u8d1f\u8377\u65e0\u5173\uff1a\u4e00\u9879\u67a2\u7ebd\u6027\u8bd5\u9a8c\u7684\u4e9a\u7ec4\u5206\u6790<br \/><\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u51fa\u7248\u7269\u7f16\u53f7\uff1a5221 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 617. \u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff1a <br \/>\u5e02\u552e<br \/>\u7597\u6cd5\uff1a\u6d77\u62a5III <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u6d77\u62a5\u5c55\u793a <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> 2025\u5e7412\u67088\u65e5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4e0b\u53486:00 -\u665a\u4e0a8:00 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> OCCC -\u897f\u5927\u5385B3-B4 <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> Cho W, et al, <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u7528\u4e8e\u6cbb\u7597CD123\u9633\u6027<br \/>\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\u7684Tagraxofusp\u548c\u4f4e\u5f3a\u5ea6\u5316\u7597* <\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\"> \u4ec5\u5728\u7ebf\u51fa\u7248\u7269 <\/span><\/p>\n<\/div>\n<p>*\u8868\u793a\u7814\u7a76\u8005\u8d5e\u52a9\u7684\u7814\u7a76\u6216\u5408\u4f5c\u7814\u7a76\u3002<\/p>\n<p>ELZONRIS\u4e8e  <a href=\"http:\/\/www.elzonris.com\/\" target=\"_blank\" rel=\"noopener\"> 2018\u5e7412\u6708<\/a> \u88abFDA\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u4e24\u5c81\u53ca\u4ee5\u4e0a\u6210\u4eba\u548c\u513f\u7ae5\u60a3\u8005\u7684\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624(BPDCN)\uff0c\u5305\u62ec\u521d\u6cbb\u548c\u65e2\u5f80\u6cbb\u7597\u4eba\u7fa4\u3002 <a href=\"https:\/\/www.menarini.com\/en-us\/news\/news-archive\/article-details\/menarini-receives-european-commission-approval-of-elzonris-tagraxofusp-for-the-treatment-of-blastic-plasmacytoid-dendritic-cell-neoplasm-bpdcn\" target=\"_blank\" rel=\"noopener\"> 2021\u5e741\u6708<\/a> \uff0cELZONRIS\u83b7\u5f97\u6b27\u76df\u59d4\u5458\u4f1a\u6279\u51c6\u3002<\/p>\n<p> \u5173\u4e8eBPDCN <\/p>\n<p>\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u662f\u4e00\u79cd\u9ad8\u5ea6\u4fb5\u88ad\u6027\u7684\u5b64\u513f\u8840\u6db2\u6076\u6027\u80bf\u7624\uff0c\u4e3b\u8981\u5f71\u54cd\u76ae\u80a4\u3001\u9aa8\u9ad3\u548c\u8840\u6db2\u3002\u5b83\u8fd8\u53ef\u4ee5\u5f71\u54cd\u8eab\u4f53\u7684\u5176\u4ed6\u90e8\u4f4d\uff0c\u5982\u6dcb\u5df4\u7ed3\u3001\u813e\u810f\u3001\u809d\u810f\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3002\u5927\u7ea685%\u81f390%\u7684\u60a3\u8005\u5728\u51fa\u73b0BPDCN\u7684\u7b2c\u4e00\u4e2a\u4f53\u5f81\u65f6\u4f1a\u51fa\u73b0\u76ae\u80a4\u75c5\u53d8\u3002BPDCN\u5f71\u54cd\u6240\u6709\u79cd\u65cf\u548c\u5730\u7406\u4f4d\u7f6e\u7684\u6240\u6709\u4eba\uff0c\u5168\u7403\u6d41\u884c\u7387\u53ef\u80fd\u5728\u6bcf\u5e74\u6bcf10\u4e07\u4eba0.4 \u2013 0.5\u4e4b\u95f4\u3002\u867d\u7136BPDCN\u5f71\u54cd\u6240\u6709\u5e74\u9f84\u6bb5\u7684\u7537\u6027\u548c\u5973\u6027\uff0c\u4f4675%\u7684\u75c5\u4f8b\u53d1\u751f\u5728\u7537\u6027\uff0c\u4e2d\u4f4d\u5e74\u9f84\u4e3a60-70\u5c81\u3002BPDCN\u764c\u7ec6\u80de\u7684\u4e00\u4e2a\u5173\u952e\u7279\u5f81\u662f\u5b83\u4eec\u9ad8\u8868\u8fbe\u4e00\u79cd\u540d\u4e3aCD123\u7684\u86cb\u767d\u8d28\uff0c\u8fd9\u53ef\u4ee5\u5728\u7ec6\u80de\u8868\u9762\u89c2\u5bdf\u5230\u3002\u8fd9\u4f7f\u5f97CD123\u6210\u4e3a\u5173\u952e\u7684\u8bca\u65ad\u6807\u5fd7\u7269\uff0c\u4e5f\u662f\u76f4\u63a5\u653b\u51fb\u764c\u75c7\u7684\u7cbe\u51c6\u6cbb\u7597\u7684\u4e3b\u8981\u9776\u70b9\u3002<\/p>\n<p> \u5173\u4e8eELZONRIS \u00a0\u00ae\uff08tagraxofusp-erzs\uff09 <\/p>\n<p> \u7f8e\u56fd\u9002\u5e94\u75c7\uff1aELZONRIS\uff08tagraxofusp-erzs\uff09\u662f\u4e00\u79cd\u5904\u65b9\u836f\uff0c\u7528\u4e8e\u6cbb\u75972\u5c81\u53ca\u4ee5\u4e0a\u6210\u4eba\u548c\u513f\u7ae5\u60a3\u8005\u7684\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u3002<\/p>\n<p>\u6709\u5173\u7f8e\u56fd\u7684\u5b8c\u6574\u5904\u65b9\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee<a href=\"http:\/\/www.elzonris.com\/\" target=\"_blank\" rel=\"noopener\">\u00a0www.elzonris.com<\/a> \u3002<\/p>\n<p> \u91cd\u8981\u5b89\u5168\u4fe1\u606f\uff0cELZONRIS \u00ae <\/p>\n<p> \u76d2\u88c5\u8b66\u544a\uff1a\u6bdb\u7ec6\u8840\u7ba1\u6cc4\u6f0f\u7efc\u5408\u5f81<\/p>\n<p>\u63a5\u53d7ELZONRIS\u7684\u60a3\u8005\u53ef\u80fd\u53d1\u751f\u5371\u53ca\u751f\u547d\u6216\u81f4\u547d\u7684\u6bdb\u7ec6\u8840\u7ba1\u6cc4\u6f0f\u7efc\u5408\u5f81(CLS)\u3002\u76d1\u6d4bCLS\u7684\u4f53\u5f81\u548c\u75c7\u72b6\uff0c\u5e76\u91c7\u53d6\u5efa\u8bae\u7684\u63aa\u65bd\u3002<\/p>\n<p> \u8b66\u544a\u548c\u6ce8\u610f\u4e8b\u9879 <\/p>\n<p> \u6bdb\u7ec6\u8840\u7ba1\u6cc4\u6f0f\u7efc\u5408\u5f81 <\/p>\n<p>\u5728\u63a5\u53d7ELZONRIS\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u5df2\u6709\u6bdb\u7ec6\u8840\u7ba1\u6cc4\u6f0f\u7efc\u5408\u5f81\uff08CLS\uff09\u7684\u62a5\u9053\uff0c\u5305\u62ec\u5371\u53ca\u751f\u547d\u548c\u81f4\u547d\u7684\u75c5\u4f8b\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u63a5\u53d7ELZONRIS\u7684\u60a3\u8005\u4e2d\uff0cCLS\u7684\u603b\u53d1\u75c5\u7387\u4e3a53%\uff0865\/122\uff09\uff0c\u5305\u62ec43%\uff0852\/122\uff09\u7684\u60a3\u8005\u4e3a1\u62162\u7ea7\uff0c7%\uff088\/122\uff09\u7684\u60a3\u8005\u4e3a3\u7ea7\uff0c1%\uff081\/122\uff09\u7684\u60a3\u8005\u4e3a4\u7ea7\uff0c\u4ee5\u53ca4\u4f8b\u6b7b\u4ea1\uff083%\uff09\u3002\u53d1\u75c5\u7684\u4e2d\u4f4d\u65f6\u95f4\u4e3a4\u5929\uff08\u8303\u56f4- 1\u81f346\u5929\uff09\uff0c\u96645\u540d\u60a3\u8005\u5916\uff0c\u6240\u6709\u60a3\u8005\u5728\u7b2c1\u5468\u671f\u4e2d\u90fd\u7ecf\u5386\u4e86\u4e00\u6b21\u4e8b\u4ef6\u3002<\/p>\n<p>\u5728\u5f00\u59cb\u4f7f\u7528ELZONRIS\u6cbb\u7597\u4e4b\u524d\uff0c\u8bf7\u786e\u4fdd\u60a3\u8005\u5177\u6709\u8db3\u591f\u7684\u5fc3\u810f\u529f\u80fd\uff0c\u5e76\u4e14\u8840\u6e05\u767d\u86cb\u767d\u5927\u4e8e\u6216\u7b49\u4e8e3.2 g\/dL\u3002\u5728ELZONRIS\u6cbb\u7597\u671f\u95f4\uff0c\u5728\u5f00\u59cb\u6bcf\u6b21ELZONRIS\u7ed9\u836f\u524d\u548c\u7ed9\u836f\u540e\u6839\u636e\u4e34\u5e8a\u6307\u5f81\u76d1\u6d4b\u8840\u6e05\u767d\u86cb\u767d\u6c34\u5e73\uff0c\u5e76\u8bc4\u4f30\u60a3\u8005\u662f\u5426\u5b58\u5728CLS\u7684\u5176\u4ed6\u4f53\u5f81\u6216\u75c7\u72b6\uff0c\u5305\u62ec\u4f53\u91cd\u589e\u52a0\u3001\u65b0\u53d1\u6c34\u80bf\u6216\u6c34\u80bf\u6076\u5316\uff0c\u5305\u62ec\u80ba\u6c34\u80bf\u3001\u4f4e\u8840\u538b\u6216\u8840\u6d41\u52a8\u529b\u5b66\u4e0d\u7a33\u5b9a\u3002<\/p>\n<p> \u8d85\u654f\u53cd\u5e94 <\/p>\n<p>ELZONRIS\u53ef\u5f15\u8d77\u4e25\u91cd\u7684\u8d85\u654f\u53cd\u5e94\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u63a5\u53d7ELZONRIS\u7684\u60a3\u8005\u4e2d\uff0c43%\uff0853\/122\uff09\u7684\u60a3\u8005\u62a5\u544a\u4e86\u8d85\u654f\u53cd\u5e94\uff0c7%\uff089\/122\uff09\u7684\u60a3\u8005\u62a5\u544a\u4e86\u2265 3\u7ea7\u53cd\u5e94\u3002\u5728\u2265 5%\u7684\u60a3\u8005\u4e2d\u62a5\u544a\u7684\u8d85\u654f\u53cd\u5e94\u8868\u73b0\u5305\u62ec\u76ae\u75b9\u3001\u7619\u75d2\u548c\u53e3\u8154\u708e\u3002\u76d1\u6d4b\u60a3\u8005\u5728\u4f7f\u7528ELZONRIS\u6cbb\u7597\u671f\u95f4\u7684\u8d85\u654f\u53cd\u5e94\u3002\u5982\u679c\u53d1\u751f\u8d85\u654f\u53cd\u5e94\uff0c\u8bf7\u4e2d\u65adELZONRIS\u8f93\u6ce8\uff0c\u5e76\u6839\u636e\u9700\u8981\u63d0\u4f9b\u652f\u6301\u6027\u62a4\u7406\u3002<\/p>\n<p> \u809d\u6bd2\u6027 <\/p>\n<p>ELZONRIS\u6cbb\u7597\u4e0e\u809d\u9176\u5347\u9ad8\u76f8\u5173\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u63a5\u53d7ELZONRIS\u7684\u60a3\u8005\u4e2d\uff0cALT\u5347\u9ad8\u53d1\u751f\u7387\u4e3a79%\uff0896\/122\uff09\uff0c\u5e94\u7528\u5b89\u5168\u6d4b\u8bd5\u5347\u9ad8\u53d1\u751f\u7387\u4e3a76%\uff0893\/122\uff09\u300226%\uff0832\/122\uff09\u7684\u60a3\u8005\u62a5\u544a\u4e863\u7ea7ALT\u5347\u9ad8\u300230%\uff0836\/122\uff09\u7684\u60a3\u8005\u62a5\u544a\u4e863\u7ea7\u5e94\u7528\u5b89\u5168\u6d4b\u8bd5\u5347\u9ad8\uff0c3%\uff084\/122\uff09\u7684\u60a3\u8005\u62a5\u544a\u4e864\u7ea7\u5e94\u7528\u5b89\u5168\u6d4b\u8bd5\u5347\u9ad8\u3002\u5728\u7b2c1\u5468\u671f\u4e2d\uff0c\u5927\u591a\u6570\u60a3\u8005\u7684\u809d\u9176\u5347\u9ad8\uff0c\u5e76\u4e14\u5728\u5242\u91cf\u4e2d\u65ad\u540e\u662f\u53ef\u9006\u7684\u3002<\/p>\n<p>\u5728\u6bcf\u6b21\u8f93\u6ce8ELZONRIS\u4e4b\u524d\u76d1\u6d4b\u4e19\u6c28\u9178\u6c28\u57fa\u8f6c\u79fb\u9176\uff08ALT\uff09\u548c\u5929\u51ac\u6c28\u9178\u6c28\u57fa\u8f6c\u79fb\u9176\uff08AST\uff09\u5e94\u7528\u5b89\u5168\u6d4b\u8bd5\u3002\u5982\u679c\u8f6c\u6c28\u9176\u5347\u9ad8\u5230\u8d85\u8fc7\u6b63\u5e38\u4e0a\u9650\u76845\u500d\uff0c\u5219\u6682\u505cELZONRIS\uff0c\u5e76\u5728\u6b63\u5e38\u5316\u6216\u89e3\u51b3\u540e\u6062\u590d\u6cbb\u7597\u3002<\/p>\n<p> \u4e0d\u826f\u53cd\u5e94 <\/p>\n<p>\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\uff08\u53d1\u751f\u7387\u2265 30%\uff09\u5305\u62ec\u6bdb\u7ec6\u8840\u7ba1\u6e17\u6f0f\u7efc\u5408\u5f81\u3001\u6076\u5fc3\u3001\u75b2\u52b3\u3001\u53d1\u70ed\u3001\u5916\u8bbe\u6c34\u80bf\u548c\u4f53\u91cd\u589e\u52a0\u3002\u6700\u5e38\u89c1\u7684\u5b9e\u9a8c\u5ba4\u5f02\u5e38\uff08\u53d1\u751f\u7387\u2265 50%\uff09\u662f\u767d\u86cb\u767d\u3001\u8840\u5c0f\u677f\u3001\u8840\u7ea2\u86cb\u767d\u3001\u9499\u548c\u94a0\u7684\u964d\u4f4e\uff0c\u4ee5\u53ca\u8461\u8404\u7cd6\u3001ALT\u548c\u5e94\u7528\u5b89\u5168\u6d4b\u8bd5\uff08AST\uff09\u7684\u5347\u9ad8\u3002<\/p>\n<p>\u8bf7\u53c2\u9605\u5b8c\u6574\u7684  <a href=\"http:\/\/pi.elzonris.com\/\" target=\"_blank\" rel=\"noopener\">\u5904\u65b9\u4fe1\u606f<\/a>\uff0c\u5305\u62ec\u76d2\u88c5\u8b66\u544a\u3002<\/p>\n<p>\u5982\u9700\u62a5\u544a\u7591\u4f3c\u4e0d\u826f\u53cd\u5e94\uff0c\u8bf7\u81f4\u75351-877-332-7961\u8054\u7cfbStemline Therapeutics, Inc.\uff0c\u6216\u81f4\u75351-800-FDA-1088\u6216<a href=\"https:\/\/www.fda.gov\/medwatch\" target=\"_blank\" rel=\"noopener\">www.fda.gov\/medwatch <\/a>\u8054\u7cfbFDA\u3002<\/p>\n<p>###<\/p>\n<p>\u5173\u4e8e\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2<\/p>\n<p>\u7f8e\u7eb3\u91cc\u5c3c\u662f\u4e00\u5bb6\u56fd\u9645\u9886\u5148\u7684\u5236\u836f\u548c\u8bca\u65ad\u516c\u53f8\uff0c\u8425\u4e1a\u989d\u8fbe47\u4ebf\u7f8e\u5143\uff0c\u62e5\u670917,000\u591a\u540d\u5458\u5de5\u3002\u7f8e\u7eb3\u91cc\u5c3c\u4e13\u6ce8\u4e8e\u5fc3\u810f\u75c5\u3001\u764c\u75c7\u3001\u80ba\u75c5\u3001\u80c3\u80a0\u75c5\u3001\u4f20\u67d3\u75c5\u3001\u7cd6\u5c3f\u75c5\u3001\u708e\u75c7\u548c\u9547\u75db\u65b9\u9762\u7b49\u4ea7\u54c1\u9700\u6c42\u7f3a\u53e3\u5de8\u5927\u7684\u6cbb\u7597\u9886\u57df\u3002Menarini\u62e5\u670918\u4e2a\u751f\u4ea7\u57fa\u5730\u548c9\u4e2a\u7814\u53d1\u4e2d\u5fc3\uff0c\u4ea7\u54c1\u7545\u9500\u5168\u7403140\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee<a href=\"https:\/\/www.menarini.com\/\" target=\"_blank\" rel=\"noopener\">www.menarini.com<\/a>\u3002<\/p>\n<p>\u5173\u4e8eStemline Therapeutics Inc.<\/p>\n<p>Stemline Therapeutics, Inc.\uff08\u7b80\u79f0Stemline\uff09\u662fMenarini Group\u65d7\u4e0b\u7684\u5168\u8d44\u5b50\u516c\u53f8\uff0c\u662f\u4e00\u5bb6\u5904\u4e8e\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\uff0c\u81f4\u529b\u4e8e\u4e3a\u60a3\u8005\u63d0\u4f9b\u53d8\u9769\u6027\u80bf\u7624\u6cbb\u7597\u65b9\u6848\u3002\u5728\u7f8e\u56fd\u3001\u6b27\u6d32\u53ca\u5168\u7403\u5176\u4ed6\u5730\u533a\uff0cStemline\u5546\u4e1a\u5316\u63a8\u5e7f\u53e3\u670d\u5185\u5206\u6ccc\u6cbb\u7597\u836f\u7269elacestrant\uff0c\u8be5\u836f\u9002\u7528\u4e8e\u6cbb\u7597\u96cc\u6fc0\u7d20\u53d7\u4f53\uff08ER\uff09\u9633\u6027\u3001\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532\uff08HER2\uff09\u9634\u6027\u3001ESR1 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Menarini Industrie Farmaceutiche Riunite<\/p>","protected":false},"excerpt":{"rendered":"<p>\u6570\u636e\u8de8\u8d8a\u4e94\u4efd\u6458\u8981\uff0c\u5305\u62ec\u4e24\u4efd\u53e3\u5934\u62a5\u544a\uff0c\u5176\u4e2d\u6709\u9488\u5bf9\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u60a3\u8005\u7684\u91cd\u8981\u53d1\u73b0 BPDCN\u662f\u4e00\u79cd\u9ad8\u5ea6\u4fb5\u88ad\u6027\u7684\u5b64\u513f\u8840\u6db2\u6076\u6027\u80bf\u7624\uff0c\u4e3b\u8981\u5f71\u54cd\u76ae\u80a4\u3001\u9aa8\u9ad3\u548c\u8840\u6db2 \u610f\u5927\u5229\u4f5b\u7f57\u4f26\u8428\u548c\u7ebd\u7ea62025\u5e7411\u670825\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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(&#8220;Stemline&#8221;)\uff0c\u4eca\u5929\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5c06\u572812\u67086\u65e5\u81f39\u65e5\u5728\u5965\u5170\u591a\u4e3e\u884c\u7684\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a(ASH)\u5e74\u4f1a\u4e0a\u5c55\u793a\u4e0eELZONRIS \u00ae (tagraxofusp-erzs)\u76f8\u5173\u7684\u65b0\u6570\u636e\u3002 \u6f14\u793a\u6587\u7a3f\u5305\u62ec\u53e3\u5934\u5f3a\u8c03\u4e09\u8054\u7597\u6cd5\u8054\u5408tagraxofusp\u3001\u963f\u624e\u80de\u82f7\u548cvenetoclax\u7684\u7ed3\u679c\uff0c\u8be5\u7597\u6cd5\u5728\u6bcd\u7ec6\u80de\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u7ec6\u80de\u80bf\u7624\uff08BPDCN\uff09\u60a3\u8005\u4e2d\u8bc1\u660e\u4e86\u7597\u6548\uff08\u9ad8\u7f13\u89e3\u7387\u548c\u6865\u63a5\u79fb\u690d\u7387\uff09\u548c\u8010\u53d7\u6027\u3002 \u201c\u5728Menarini Stemline\uff0c\u6211\u4eec\u575a\u5b9a\u4e0d\u79fb\u5730\u81f4\u529b\u4e8e\u6539\u53d8\u96be\u4ee5\u6cbb\u7597\u7684\u764c\u75c7\u60a3\u8005\u7684\u751f\u6d3b\uff0c\u201d\u7f8e\u7eb3\u91cc\u5c3c\u96c6\u56e2\u9996\u5e2d\u6267\u884c\u5b98Elcin Barker Ergun\u8868\u793a\u3002\u201c\u8fd9\u4e9b\u6570\u636e\u8868\u660e\uff0ctagraxofusp\u5728BPDCN\u7684\u5355\u836f\u6cbb\u7597\u548c\u8054\u5408\u6cbb\u7597\u4e2d\u90fd\u8d77\u7740\u91cd\u8981\u4f5c\u7528\uff0c\u5e76\u4e14\u5b83\u4e5f\u6709\u6f5c\u529b\u5e2e\u52a9\u60a3\u6709\u5176\u4ed6\u4fb5\u88ad\u6027\u8840\u6db2\u6076\u6027\u80bf\u7624\u7684\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u8feb\u5207\u9700\u8981\u66f4\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6848\u3002\u201d \u6709\u5173Menarini Group\/Stemline Therapeutics\u5373\u5c06\u53d1\u8868\u7684\u6f14\u8bb2\u548c\u51fa\u7248\u7269\u7684\u5b8c\u6574\u8be6\u7ec6\u4fe1\u606f\uff0c\u8bf7\u53c2\u9605\u4e0b\u6587\uff1a 2025\u5e74\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a\uff08ASH\uff09\u5e74\u4f1a \u4e3b\u8981\u4f5c\u8005 \u6807\u9898\u548c\u51fa\u7248\u7269\u7f16\u53f7 \u8bfe\u6b21\u540d\u79f0 \u6f14\u8bb2\u8be6\u60c5 Navarro Vicente I, et al. 257\u540d\u60a3\u6709\u6210\u7ea4\u7ef4\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u72b6\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u60a3\u8005\u7684\u75be\u75c5\u8868\u73b0\u548c\u514d\u75ab\u8868\u578b\u7279\u5f81\uff1a\u4e00\u9879PETHEMA\/PALG\u7814\u7a76* \u51fa\u7248\u7269\u7f16\u53f7\uff1a218 618. \u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff1a \u8bca\u65ad\u548c\u9884\u540e\u4e2d\u7684\u751f\u7269\u6807\u5fd7\u7269\u548c\u5206\u5b50\u6807\u5fd7\u7269\uff1a \u91cd\u65b0\u5b9a\u4e49AML\uff1a\u9057\u4f20\u3001\u8868\u578b\u548c\u57fa\u4e8e\u53cd\u5e94\u7684\u89c1\u89e3 \u53e3\u5934\u62a5\u544a 2025\u5e7412\u67086\u65e5 \u4e0b\u53482:15 -\u4e0b\u53482:30 OCCC &#8211; 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