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href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04353375\" target=\"_blank\" rel=\"noopener\">NCT04353375<\/a>\u67e5\u770b\u3002<\/p>\n<p>\u5173\u4e8e\u51e1\u745e\u683c\u62c9\u66ff\u5c3c<\/p>\n<p>\u51e1\u745e\u683c\u62c9\u66ff\u5c3c\uff08HMPL-453\uff09\u662f\u4e00\u79cd\u65b0\u578b\u3001\u9ad8\u9009\u62e9\u6027\u4e14\u5f3a\u6548\u7684FGFR 1\u30012\u548c3\u6291\u5236\u5242\u3002\u5f02\u5e38\u7684FGFR\u4fe1\u53f7\u4f20\u5bfc\u5df2\u88ab\u53d1\u73b0\u662f\u80bf\u7624\u751f\u957f\u3001\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\u53ca\u6297\u80bf\u7624\u6cbb\u7597\u6297\u6027\u4ea7\u751f\u7684\u8bf1\u56e0\u3002\u5f02\u5e38\u7684 FGFR 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class=\"prnml4\"><span class=\"prnews_span\">[1] \u00a0 Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition). Chin J Clin Med. 2025;32(1):1-18.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[2] \u00a0 Arai Y, Totoki Y, Hosoda F, et al. Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.\u00a0Hepatology.\u00a02014;59:1427\u201334.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[3] \u00a0 Nakamura H, Arai Y, Totoki Y, et al. Genomic spectra of biliary tract cancer.\u00a0Nat Genet.\u00a02015;47:1003\u201310.<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>SOURCE \u548c\u9ec4\u533b\u836f(\u4e2d\u56fd)\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"<p>\u2014 \u57fa\u4e8e\u4e00\u9879\u4e2d\u56fdII\u671f\u6ce8\u518c\u7814\u7a76\u7ed3\u679c\u63d0\u4ea4\u8be5\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7 \u2014\u2014 \u4ec5\u6b21\u4e8e\u809d\u7ec6\u80de\u764c\u7684\u7b2c\u4e8c\u5927\u5e38\u89c1\u809d\u764c\u7c7b\u578b\uff0c\u957f\u671f\u751f\u5b58\u7387\u4e00\u822c\u76f8\u5bf9\u8f83\u5dee\u00a0\u2014 \u9999\u6e2f\u3001\u4e0a\u6d77\u548c\u65b0\u6cfd\u897f\u5dde\u5f17\u6d1b\u52d2\u59c6\u516c\u56ed2025\u5e7412\u670829\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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[1] \u00a0 Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition). Chin J Clin Med. 2025;32(1):1-18. [2] \u00a0 Arai Y, Totoki Y, Hosoda F, et al. Fibroblast growth factor receptor 2 tyrosine kinase fusions [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":20318,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-20317","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u548c\u9ec4\u533b\u836f\u5ba3\u5e03\u51e1\u745e\u683c\u62c9\u66ff\u5c3c (HMPL-453) \u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u809d\u5185\u80c6\u7ba1\u764c\u7684\u4e2d\u56fd\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u53d7\u7406\u5e76\u83b7\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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[1] \u00a0 Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition). Chin J Clin Med. 2025;32(1):1-18. [2] \u00a0 Arai Y, Totoki Y, Hosoda F, et al. Fibroblast growth factor receptor 2 tyrosine kinase fusions [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u548c\u9ec4\u533b\u836f\u5ba3\u5e03\u51e1\u745e\u683c\u62c9\u66ff\u5c3c-hmpl-453-\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u809d\u5185\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-29T09:43:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" 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[1] \u00a0 Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition). Chin J Clin Med. 2025;32(1):1-18. [2] \u00a0 Arai Y, Totoki Y, Hosoda F, et al. 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