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class=\"prnml4\"><span class=\"prnews_span\">\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[1]. Pal Singh, S., F. Dammeijer, and R.W. Hendriks, Role of Bruton&#8217;s tyrosine kinase in B cells and malignancies. Molecular Cancer, 2018. 17(1).<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[2]. Mirre De Bondt, Janne Renders, Sofie Struyf, Niels Hellings, Inhibitors of Bruton&#8217;s tyrosine kinase as emerging therapeutic strategy in autoimmune diseases Autoimmunity Reviews, Volume 23, Issue 5, 2024.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[3]. Wang, E., et al., Mechanisms of Resistance to Noncovalent Bruton&#8217;s Tyrosine Kinase Inhibitors. New England Journal of Medicine, 2022. 386(8): p. 735-743.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[4]. Zhang, D., et al., NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood, 2023. 141(13): p. 1584-1596.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[5]. Wu, Y., et al., Translational modelling to predict human pharmacokinetics and pharmacodynamics of a Bruton&#8217;s tyrosine kinase\u2010targeted protein degrader BGB\u201016673. 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\u53c2\u8003\u6587\u732e\uff1a [1]. Pal Singh, S., F. Dammeijer, and R.W. Hendriks, Role of Bruton&#8217;s tyrosine kinase in B cells and malignancies. Molecular Cancer, 2018. 17(1). [2]. Mirre De Bondt, Janne Renders, Sofie Struyf, Niels Hellings, [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":20486,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-20485","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u4e9a\u76db\u533b\u836fBTK\u964d\u89e3\u5242APG-3288\u7684\u65b0\u836f\u4e34\u5e8a\u7533\u8bf7\uff08IND\uff09\u83b7\u7f8e\u56fdFDA\u8bb8\u53ef - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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\u53c2\u8003\u6587\u732e\uff1a [1]. Pal Singh, S., F. Dammeijer, and R.W. Hendriks, Role of Bruton&#8217;s tyrosine kinase in B cells and malignancies. Molecular Cancer, 2018. 17(1). [2]. 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\u53c2\u8003\u6587\u732e\uff1a [1]. Pal Singh, S., F. Dammeijer, and R.W. Hendriks, Role of Bruton&#8217;s tyrosine kinase in B cells and malignancies. Molecular Cancer, 2018. 17(1). [2]. 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