{"id":21667,"date":"2026-02-12T00:15:00","date_gmt":"2026-02-12T00:15:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/"},"modified":"2026-02-12T00:15:00","modified_gmt":"2026-02-12T00:15:00","slug":"%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/","title":{"rendered":"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(“\u9e92\u9e9f-\u7ffc01”)\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00"},"content":{"rendered":"

\u4e0a\u6d77<\/span>2026\u5e742\u670812\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u8fd1\u65e5\u6210\u529f\u53ec\u5f00GFH375\uff08\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff09III\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u3002\u6b64\u9879\u7814\u7a76\uff08GFH375X1301\uff0c\u9e92\u9e9f-\u7ffc01\uff09\u4e8e2025\u5e7411\u6708\u5728\u9996\u5bb6\u4e2d\u5fc3\u542f\u52a8\uff0c\u9488\u5bf9\u80f0\u817a\u764cKRAS\u7a81\u53d8\u5360\u6bd4\u6700\u9ad8\u7684G12D\u7a81\u53d8\u578b\u60a3\u8005\u5f00\u5c55\uff0c\u4e3a\u5168\u7403\u9996\u4e2a\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u7684III\u671f\u7814\u7a76\u3002\u6765\u81ea\u5168\u56fd\u7684\u6570\u5341\u5bb6\u7814\u7a76\u4e2d\u5fc3\u4e13\u5bb6\u4ee3\u8868\u9f50\u805a\u5317\u4eac\uff0c\u56f4\u7ed5\u9879\u76ee\u7684\u65e2\u5f80\u5165\u7ec4\u7ecf\u9a8c\u3001\u6cbb\u7597\u6548\u679c\u3001\u4ee5\u53ca\u540e\u7eed\u9879\u76ee\u7ba1\u7406\u8fdb\u884c\u6df1\u5ea6\u4ea4\u6d41\u3002<\/p>\n

\n

<\/a><\/p>\n<\/div>\n

\u8be5\u7814\u7a76\u7275\u5934\u5355\u4f4d\u4e3a\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff0c\u9879\u76ee\u5c06\u5728\u8d85\u8fc740\u5bb6\u7814\u7a76\u4e2d\u5fc3\u5f00\u5c55\u3001\u8ba1\u5212\u5165\u7ec4\u6570\u767e\u4f8b\u65e2\u5f80\u63a5\u53d7\u81f3\u5c11\u4e00\u79cd\u6807\u51c6\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u80f0\u817a\u764c\u60a3\u8005\uff1b\u8be5\u8bd5\u9a8c\u6307\u5bfc\u59d4\u5458\u4f1a\u5916\u90e8\u4e13\u5bb6\u5305\u62ec\u5317\u4eac\u534f\u548c\u533b\u9662\u540d\u8a89\u9662\u957f\u8d75\u7389\u6c9b\u9662\u58eb\u3001\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3Dexeus\u5927\u5b66\u533b\u9662Rafael Rosell\u6559\u6388\u53ca\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u6c88\u7433\u6559\u6388\u3002<\/p>\n

\u653b\u575a”\u764c\u4e2d\u4e4b\u738b”\uff0c\u6784\u5efaRAS\u8d5b\u9053\u5934\u90e8\u4f01\u4e1a\u4f18\u52bf<\/p>\n

\u52b2\u65b9\u533b\u836f\u8463\u4e8b\u957f\u5415\u5f3a\u535a\u58eb\u5f00\u573a\u65f6\u8f6c\u8fbe\u4e86\u8d75\u7389\u6c9b\u9662\u58eb\u7684\u4e66\u9762\u8d3a\u8f9e\uff0c\u663e\u793a\u4e86\u5176\u5bf9\u8bd5\u9a8c\u5f00\u5c55\u7684\u671f\u5f85\u548c\u4fe1\u5fc3\u3002”GFH375\u662f\u5168\u7403\u9996\u4e2a\u8fdb\u5165\u4e09\u671f\u8bd5\u9a8c\u7684\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff0c\u8fd9\u9879\u7814\u7a76\u5bf9\u80f0\u817a\u764c\u7684\u6cbb\u7597\u5177\u6709\u6f5c\u5728\u7684\u7a81\u7834\u610f\u4e49\u3002\u5e0c\u671b\u5404\u4f4d\u7814\u7a76\u8005\u5728\u8fd9\u9879\u4e09\u671f\u8bd5\u9a8c\u4e2d\u901a\u529b\u5408\u4f5c\uff0c\u4e3a\u4e2d\u56fd\u80fd\u591f\u9886\u5148\u4e16\u754c\u80f0\u817a\u75c5\u4e34\u5e8a\u7814\u7a76\u505a\u51fa\u4e00\u4efd\u8d21\u732e\u3002\u611f\u8c22\u52b2\u65b9\u533b\u836f\u7684\u52aa\u529b\u548c\u5949\u732e\uff0c\u9884\u795d\u8be5\u8bd5\u9a8c\u53d6\u5f97\u7406\u60f3\u6210\u679c\uff01”<\/p>\n

\n

<\/a><\/p>\n<\/div>\n

\u6b64\u9879\u7814\u7a76\u7684Leading PI\u6c88\u7433\u6559\u6388\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u56de\u987e\u4e86GFH375\u5728\u524d\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u7814\u7a76\u6210\u679c\uff0c\u5e76\u5bf9\u6574\u4f53III\u671f\u7814\u7a76\u63d0\u51fa\u4e86\u89c4\u5212\u4e0e\u671f\u5f85\u3002”\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230GFH375\u5df2\u7ecf\u5c55\u73b0\u4e86\u6cbb\u7597\u80f0\u817a\u764c\u7684\u5b89\u5168\u6027\u548c\u4f18\u79c0\u7597\u6548\uff0c\u4e5f\u611f\u53d7\u5230\u4e86\u60a3\u8005\u5bf9KRAS G12D\u9776\u5411\u7597\u6cd5\u4e0a\u5e02\u7684\u8feb\u5207\u671f\u5f85\u3002I\/II\u671f\u8bd5\u9a8c\u6210\u679c\u4e3aIII\u671f\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u575a\u5b9e\u7684\u57fa\u7840\uff0c\u4e5f\u8ba9\u5168\u56fd\u7814\u7a76\u8005\u6709\u4fe1\u5fc3\u63a8\u8fdbGFH375\u6ce8\u518c\u6027\u7814\u7a76\u3002\u6211\u4eec\u671f\u5f85\u4e0e\u2018\u764c\u4e2d\u4e4b\u738b’\u7684\u535a\u5f08\u5f81\u9014\u6d8c\u73b0\u65b0\u7684\u5e0c\u671b\uff0c\u4e5f\u671f\u5f85\u5411\u4e16\u754c\u5c55\u793a\u4f18\u79c0\u7684\u4e2d\u56fd\u521b\u65b0\u7597\u6cd5\uff0c\u4ee5\u836f\u4f01\u548c\u7814\u7a76\u8005\u7684\u5171\u540c\u52aa\u529b\u9020\u798f\u60a3\u8005\u4e0e\u793e\u4f1a\u3002”<\/p>\n

\n

<\/a><\/p>\n<\/div>\n

\u6b64\u5916\uff0c\u4f5c\u4e3a\u52b2\u65b9\u6b27\u6d32\u591a\u4e2d\u5fc3KROCUS\u7814\u7a76\uff08\u6c1f\u6cfd\u96f7\u585e\u8054\u5408\u897f\u59a5\u6614\u5355\u6297\u7684\u4e00\u7ebf\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u6848\uff09Leading PI\uff0cRafael Rosell\u6559\u6388\u4e5f\u5728\u524d\u671f\u6c9f\u901a\u4e2d\u8868\u793a\u5f88\u9ad8\u5174\u6210\u4e3a\u52b2\u65b9\u53e6\u4e00\u9879\u521b\u65b0\u7814\u7a76\u6307\u5bfc\u59d4\u5458\u4f1a\u7684\u5916\u90e8\u4e13\u5bb6\uff0c\u5e76\u4e3a\u8fd9\u9879\u91cd\u8981\u7814\u7a76\u8d21\u732e\u529b\u91cf\uff0c\u671f\u5f85\u4e0e\u59d4\u5458\u4f1a\u7684\u4e13\u5bb6\u548c\u6210\u5458\u5408\u4f5c\u3002<\/p>\n

\n

<\/a><\/p>\n<\/div>\n

\u5415\u5f3a\u535a\u58eb\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u8868\u793a\u52b2\u65b9\u7531\u6d77\u5f52\u79d1\u5b66\u5bb6\u534f\u529b\u6253\u9020\u3001\u63a2\u7d22\u539f\u521b\u578b”\u5168\u7403\u65b0”\u836f\u7269\u5f00\u53d1\uff0c\u6210\u7acb\u4e03\u5e74\u540e\u8fce\u6765\u516c\u53f8\u9996\u4e2a\u4e0a\u5e02\u4ea7\u54c1\u6c1f\u6cfd\u96f7\u585e\uff08\u56fd\u5185\u9996\u6b3e\u3001\u5168\u7403\u7b2c\u4e09\u6b3e\u83b7\u6279\u7684KRAS G12C\u6291\u5236\u5242\uff09\uff0c\u5e76\u4ee5\u6c1f\u6cfd\u96f7\u585e\u7684\u7814\u53d1\u7ecf\u9a8c\u6253\u9020\u4e86\u4e00\u4f53\u5316RAS\u7597\u6cd5\u5f00\u53d1\u4f53\u7cfb\u3002”GFH375\u5728\u56fd\u5185\u4e34\u5e8a\u83b7\u6279\u540e\u4e09\u4e2a\u5b63\u5ea6\u5185\u8fdb\u5165II\u671f\u3001\u4e00\u5e74\u534a\u4e4b\u5185\u8fdb\u5165III\u671f\uff0c\u9ad8\u6548\u4e34\u5e8a\u8fdb\u5c55\u663e\u793a\u4e86\u52b2\u65b9\u901f\u5ea6\u548c\u4ea7\u54c1\u4f18\u6548\u3002GFH375\u662f\u52b2\u65b9RAS\u7597\u6cd5\u5f00\u53d1\u7684\u65b0\u8d77\u70b9\u2014\u2014\u516c\u53f8\u540e\u7eed\u7684\u591a\u5143\u5206\u5b50\u5f62\u6001RAS\u7597\u6cd5\uff0c\u5305\u62ec\u5168\u7403\u7b2c\u4e09\u6b3e\u4e34\u5e8a\u9636\u6bb5\u5206\u5b50\u80f6\u6cdbRAS\u6291\u5236\u5242GFH276\uff08I\/II\u671f\uff09\u3001\u5168\u7403\u9996\u6b3e\u6cdbRAS\u6297\u4f53\u5076\u8054\u836f\u7269GFS784\uff08IND\u53d7\u7406\uff09\uff0c\u8be5\u7cfb\u5217\u8fd8\u6709\u671b\u5f62\u6210\u534f\u540c\u6027\u80f0\u817a\u764c\u6cbb\u7597\u77e9\u9635\u3002\u672a\u6765\u52b2\u65b9\u5c06\u4ee5\u6301\u7eed\u63d0\u5347\u7684\u56fd\u9645\u7ade\u4e89\u529b\uff0c\u5851\u9020\u5168\u7403RAS\u8d5b\u9053\u7684\u9886\u5148\u4f01\u4e1a\uff0c\u8df5\u884c\u2018\u6025\u4e34\u5e8a\u672a\u7ade\u3001\u521b\u5168\u7403\u65b0\u836f’\u7684\u4f7f\u547d\u3002”<\/p>\n

\u9e92\u9e9f\u5c55”\u7ffc”\uff0c\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u65b0\u5f81\u7a0b<\/p>\n

\u80f0\u817a\u764c\u662f\u6076\u6027\u7a0b\u5ea6\u6700\u9ad8\u7684\u80bf\u7624\u4e4b\u4e00\u30015\u5e74\u751f\u5b58\u7387\u4f4e\u4e8e10%\uff0c\u76ee\u524d\u80f0\u817a\u764c\u7684\u4e00\u3001\u4e8c\u7ebf\u6807\u51c6\u6cbb\u7597\u5747\u4ee5\u5316\u7597\u4e3a\u4e3b\uff0c\u5c1a\u65e0\u8986\u76d6\u9762\u8f83\u5e7f\u7684\u76f8\u5173\u9776\u5411\u7597\u6cd5\u83b7\u6279\u4e0a\u5e02\u3002RAS\u7a81\u53d8\u5728\u80f0\u817a\u764c\u4e2d\u53d1\u751f\u7387\u9ad8\u8fbe90%\uff08KRAS G12D\u7a81\u53d8\u7387\u7ea640%\uff09\uff0cRAS\u901a\u8def\u7a81\u53d8\u53caTP53\u3001CDKN2A\u7b49\u5e38\u89c1\u5171\u7a81\u53d8\u662f\u5bfc\u81f4\u80f0\u817a\u764c\u53d1\u751f\u53d1\u5c55\u3001\u9884\u540e\u4e0d\u826f\u7684\u91cd\u8981\u56e0\u7d20\uff0cKRAS G12D\u7a81\u53d8\u66f4\u662f\u80f0\u817a\u764c\u7684\u72ec\u7acb\u9884\u540e\u4e0d\u826f\u6807\u5fd7\u3002\u65e2\u5f80\u7814\u7a76\u663e\u793a\uff0c\u76f8\u8f83\u4e8eKRAS\u91ce\u751f\u578b\u53ca\u5176\u4ed6KRAS\u7a81\u53d8\u4e9a\u578b\uff0cKRAS G12D\u7a81\u53d8\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08mRFS\uff09\u5747\u660e\u663e\u7f29\u77ed\u3002<\/p>\n

\u8fd1\u5e74\u6765\u665a\u671f\u80f0\u817a\u764c\u4e34\u5e8a\u8bd5\u9a8c\uff08\u5305\u62ec\u4e00\u7ebf\u6cbb\u7597\uff09\u9879\u76ee\u4f17\u591a\uff0cKRAS G12D\u6291\u5236\u5242\u6210\u4e3a\u5f53\u524d\u80f0\u817a\u764c\u9776\u5411\u7597\u6cd5\u5f00\u53d1\u7684\u91cd\u8981\u65b9\u5411\u3002\u4f9d\u636eESMO\u53e3\u5934\u62a5\u544a\u62ab\u9732\u7684GFH375\u5355\u836f\u7597\u6cd5\u6570\u636e\uff0c\u8be5\u4ea7\u54c1\u5355\u836f\u6cbb\u7597\u80f0\u817a\u5bfc\u7ba1\u817a\u764c\uff08PDAC\uff09\u7684\u7597\u6548\u4e3a\u5168\u7403\u540c\u7c7b\u6700\u4f73\u3002\u76ee\u524dGFH375\/VS-7375\u5df2\u8fdb\u5165\u6cbb\u7597\u4e0d\u540c\u7624\u79cd\u7684\u591a\u4e2a\u56fd\u5185\u3001\u6d77\u5916\u5355\u836f\u53ca\u8054\u5408\u7597\u6cd5\u8bd5\u9a8c\uff0c\u5176\u4e2d\u52b2\u65b9\u5df2\u5728\u56fd\u5185\u5f00\u5c55GFH375\u8054\u5408\u5316\u7597\uff08AG\uff09\u4e00\u7ebf\u6cbb\u7597PDAC\u8bd5\u9a8c\uff1b\u4e14GFH375\/VS-7375\u5df2\u83b7\u5f97FDA\u5feb\u901f\u901a\u9053\u8d44\u683c\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5404\u7ebfKRAS G12D\u7a81\u53d8\u578b\u8f6c\u79fb\u6027PDAC\u3002\u6b64\u5916\uff0cGFH375\u5355\u836f\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u7597\u6548\u53ca\u603b\u4f53\u5f00\u53d1\u8fdb\u5ea6\uff0c\u4e5f\u5728\u5168\u7403KRAS G12D\u9776\u5411\u7597\u6cd5\u4e2d\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002<\/p>\n

\u52b2\u65b9\u4e34\u5e8a\u56e2\u961f\u5728\u5927\u4f1a\u4e2d\u4ecb\u7ecd\u4e86III\u671f\u7814\u7a76\u7684\u65b9\u6848\u8bbe\u8ba1\u3001\u5165\u7ec4\u6807\u51c6\u3001\u6709\u6548\u6027\u8bc4\u4f30\u53ca\u5408\u5e76\u7528\u836f\u7b49\u5185\u5bb9\u3002\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u5468\u519b\u6559\u6388\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u674e\u82f1\u6559\u6388\u3001\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u674e\u5fd7\u4f1f\u6559\u6388\u3001\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\u5468\u9896\u73c2\u526f\u6559\u6388\u7b49\u7814\u7a76\u4e13\u5bb6\uff0c\u5728\u73b0\u573a\u6f14\u8bb2\u4e2d\u5206\u4eab\u4e86GFH375\u80f0\u817a\u764c\u6cbb\u7597\u5b9e\u8df5\u7684\u6848\u4f8b\u5206\u6790\u548c\u5b9d\u8d35\u7ecf\u9a8c\u3002\u4e0e\u4f1a\u8005\u9488\u5bf9\u6b64\u9879\u7814\u7a76\u7684\u8fdb\u5ea6\u89c4\u5212\u3001\u9879\u76ee\u7ec6\u8282\u3001\u5168\u56fd\u5404\u7814\u7a76\u4e2d\u5fc3\u7684\u6c9f\u901a\u534f\u4f5c\u7b49\u8bdd\u9898\u8fdb\u884c\u4e86\u5145\u5206\u8ba8\u8bba\uff0c\u5927\u5bb6\u671f\u5f85\u901a\u8fc7\u4ea7\u4e1a\u4e0e\u533b\u5b66\u754c\u7684\u643a\u624b\u5171\u8fdb\uff0c\u63a8\u8fdb”\u9e92\u9e9f-\u7ffc01″\u7814\u7a76\u8fdb\u5c55\u5e76\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u8fc8\u5411\u5e02\u573a\u3002<\/p>\n

\u5173\u4e8e\u52b2\u65b9\u533b\u836f<\/p>\n

\u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u662f\u4e00\u5bb6\u5168\u7403\u5e03\u5c40\u7684\u521b\u65b0\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\uff0c\u805a\u7126\u80bf\u7624\u3001\u514d\u75ab\u7c7b\u75be\u75c5\u9886\u57df\u9ad8\u5ea6\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u4ee5\u75be\u75c5\u751f\u7269\u5b66\u673a\u7406\u548c\u4e34\u5e8a\u8f6c\u5316\u533b\u5b66\u4e3a\u6838\u5fc3\uff0c\u6784\u5efa\u5e76\u53d1\u6325\u81ea\u4e3b\u5316\u3001\u4e00\u4f53\u5316\u7814\u53d1\u4f53\u7cfb\u4f18\u52bf\uff0c\u4e3b\u653b\u5c1a\u65e0\u4e34\u5e8a\u9a8c\u8bc1\u7684\u521b\u65b0\u9776\u70b9\u4e0e\u9002\u5e94\u75c7\uff0c\u5e76\u62e5\u6709\u5168\u7403\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u3002\u81ea2017\u5e74\u6210\u7acb\u4ee5\u6765\uff0c\u52b2\u65b9\u533b\u836f\u5df2\u5efa\u7acb\u5305\u542b\u591a\u4e2a\u81ea\u4e3b\u7814\u53d1\u7684”\u5168\u7403\u65b0”\u5927\u3001\u5c0f\u5206\u5b50\u9879\u76ee\uff0c\u591a\u4e2a\u4ea7\u54c1\u5728\u4e2d\u56fd\u3001\u6b27\u6d32\u3001\u7f8e\u56fd\u8fdb\u5165\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5305\u62ec\u591a\u9879\u540e\u671f\u6216\u5173\u952e\u6027\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n

\u8fbe\u4f2f\u7279\u00ae\uff08\u6c1f\u6cfd\u96f7\u585e\uff09\u4e3a\u52b2\u65b9\u7ba1\u7ebf\u4e2d\u9996\u4e2a\u56fd\u5185\u4e0a\u5e02\u83b7\u6279\u4ea7\u54c1\uff0c\u4e5f\u662f\u56fd\u5185\u9996\u4e2a\u3001\u5168\u7403\u7b2c\u4e09\u4e2a\u4e0a\u5e02\u7684KRAS G12C\u6291\u5236\u5242\uff1b\u76ee\u524d\u516c\u53f8\u5df2\u5f62\u6210RAS\u9776\u5411\u7597\u6cd5\u7684\u4e00\u4f53\u5316\u6df1\u8015\u77e9\u9635\uff0c\u5305\u62ec\u591a\u9776\u70b9\u3001\u591a\u79cd\u5206\u5b50\u7c7b\u578b\u7684\u9009\u62e9\u6027\u53ca\u6cdbRAS\u6291\u5236\u5242\uff0c\u591a\u4e2a\u4ea7\u54c1\u5f00\u53d1\u8fdb\u5ea6\u5728\u56fd\u5185\u5916\u540c\u9776\u70b9\u8d5b\u9053\u5904\u4e8e\u9886\u5148\uff0c\u4e14\u7814\u7a76\u6570\u636e\u591a\u6b21\u767b\u9646\u56fd\u9645\u5b66\u672f\u4f1a\u8bae\u7a81\u7834\u6027\u7814\u7a76\u6458\u8981\u53ca\u53e3\u5934\u62a5\u544a\u3002\u540c\u65f6\uff0c\u516c\u53f8\u79ef\u6781\u62d3\u5c55\u5176\u4ed6”\u5168\u7403\u65b0”\u9776\u5411\u836f\u5f00\u53d1\uff0c\u91c7\u7528\u534f\u540c\u673a\u5236\u6253\u9020\u5168\u7403\u9996\u521b\u7684\u591a\u7c7b\u578b\u53cc\u9776\u70b9\u7597\u6cd5\uff1b\u5e76\u7ed3\u5408\u4e34\u5e8a\u9700\u6c42\u4e0e\u6cbb\u7597\u7406\u5ff5\u7684\u521b\u65b0\uff0c\u4ee5\u4ea7\u54c1\u77e9\u9635\u8fdb\u519b\u80f0\u817a\u764c\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u6076\u75c5\u8d28\u7b49\u5927\u9002\u5e94\u75c7\u5e02\u573a\u3002<\/p>\n

\u52b2\u65b9\u5df2\u83b7\u5f97\u56fd\u5bb6\u7ea7\u4e13\u7cbe\u7279\u65b0”\u5c0f\u5de8\u4eba”\u3001\u56fd\u5bb6\u7ea7\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u79f0\u53f7\uff0c\u5e76\u83b7\u5f97\u4e0a\u6d77\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u3001\u4e0a\u6d77\u5e02\u8de8\u56fd\u516c\u53f8\u7814\u53d1\u4e2d\u5fc3\u3001\u4e0a\u6d77\u5e02\u4f01\u4e1a\u6280\u672f\u4e2d\u5fc3\u8ba4\u5b9a\u3002\u516c\u53f8\u8fd1\u5e74\u6765\u4e0d\u65ad\u6df1\u5316\u5546\u4e1a\u5408\u4f5c\u7f51\u7edc\uff0c\u5df2\u4e0e\u591a\u4e2a\u5883\u5185\u5916\u4e0a\u5e02\u516c\u53f8\u8fbe\u6210\u6218\u7565\u6388\u6743\u534f\u8bae\u3001\u6216\u5f00\u5c55”\u5168\u7403\u65b0”\u4e34\u5e8a\u5408\u4f5c\u5e76\u5df2\u53d6\u5f97\u79ef\u6781\u8fdb\u5c55\u3002<\/p>\n

\u00a0<\/p>\n

\n<\/div>\n

SOURCE \u52b2\u65b9\u533b\u836f<\/p>","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d772026\u5e742\u670812\u65e5 \/\u7f8e\u901a\u793e\/ — \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u8fd1\u65e5\u6210\u529f\u53ec\u5f00GFH375\uff08\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff09III\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u3002\u6b64\u9879\u7814\u7a76\uff08GFH375X1301\uff0c\u9e92\u9e9f-\u7ffc01\uff09\u4e8e2025\u5e7411\u6708\u5728\u9996\u5bb6\u4e2d\u5fc3\u542f\u52a8\uff0c\u9488\u5bf9\u80f0\u817a\u764cKRAS\u7a81\u53d8\u5360\u6bd4\u6700\u9ad8\u7684G12D\u7a81\u53d8\u578b\u60a3\u8005\u5f00\u5c55\uff0c\u4e3a\u5168\u7403\u9996\u4e2a\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u7684III\u671f\u7814\u7a76\u3002\u6765\u81ea\u5168\u56fd\u7684\u6570\u5341\u5bb6\u7814\u7a76\u4e2d\u5fc3\u4e13\u5bb6\u4ee3\u8868\u9f50\u805a\u5317\u4eac\uff0c\u56f4\u7ed5\u9879\u76ee\u7684\u65e2\u5f80\u5165\u7ec4\u7ecf\u9a8c\u3001\u6cbb\u7597\u6548\u679c\u3001\u4ee5\u53ca\u540e\u7eed\u9879\u76ee\u7ba1\u7406\u8fdb\u884c\u6df1\u5ea6\u4ea4\u6d41\u3002 \u8be5\u7814\u7a76\u7275\u5934\u5355\u4f4d\u4e3a\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff0c\u9879\u76ee\u5c06\u5728\u8d85\u8fc740\u5bb6\u7814\u7a76\u4e2d\u5fc3\u5f00\u5c55\u3001\u8ba1\u5212\u5165\u7ec4\u6570\u767e\u4f8b\u65e2\u5f80\u63a5\u53d7\u81f3\u5c11\u4e00\u79cd\u6807\u51c6\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u80f0\u817a\u764c\u60a3\u8005\uff1b\u8be5\u8bd5\u9a8c\u6307\u5bfc\u59d4\u5458\u4f1a\u5916\u90e8\u4e13\u5bb6\u5305\u62ec\u5317\u4eac\u534f\u548c\u533b\u9662\u540d\u8a89\u9662\u957f\u8d75\u7389\u6c9b\u9662\u58eb\u3001\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3Dexeus\u5927\u5b66\u533b\u9662Rafael Rosell\u6559\u6388\u53ca\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u6c88\u7433\u6559\u6388\u3002 \u653b\u575a”\u764c\u4e2d\u4e4b\u738b”\uff0c\u6784\u5efaRAS\u8d5b\u9053\u5934\u90e8\u4f01\u4e1a\u4f18\u52bf \u52b2\u65b9\u533b\u836f\u8463\u4e8b\u957f\u5415\u5f3a\u535a\u58eb\u5f00\u573a\u65f6\u8f6c\u8fbe\u4e86\u8d75\u7389\u6c9b\u9662\u58eb\u7684\u4e66\u9762\u8d3a\u8f9e\uff0c\u663e\u793a\u4e86\u5176\u5bf9\u8bd5\u9a8c\u5f00\u5c55\u7684\u671f\u5f85\u548c\u4fe1\u5fc3\u3002”GFH375\u662f\u5168\u7403\u9996\u4e2a\u8fdb\u5165\u4e09\u671f\u8bd5\u9a8c\u7684\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff0c\u8fd9\u9879\u7814\u7a76\u5bf9\u80f0\u817a\u764c\u7684\u6cbb\u7597\u5177\u6709\u6f5c\u5728\u7684\u7a81\u7834\u610f\u4e49\u3002\u5e0c\u671b\u5404\u4f4d\u7814\u7a76\u8005\u5728\u8fd9\u9879\u4e09\u671f\u8bd5\u9a8c\u4e2d\u901a\u529b\u5408\u4f5c\uff0c\u4e3a\u4e2d\u56fd\u80fd\u591f\u9886\u5148\u4e16\u754c\u80f0\u817a\u75c5\u4e34\u5e8a\u7814\u7a76\u505a\u51fa\u4e00\u4efd\u8d21\u732e\u3002\u611f\u8c22\u52b2\u65b9\u533b\u836f\u7684\u52aa\u529b\u548c\u5949\u732e\uff0c\u9884\u795d\u8be5\u8bd5\u9a8c\u53d6\u5f97\u7406\u60f3\u6210\u679c\uff01” \u6b64\u9879\u7814\u7a76\u7684Leading PI\u6c88\u7433\u6559\u6388\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u56de\u987e\u4e86GFH375\u5728\u524d\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u7814\u7a76\u6210\u679c\uff0c\u5e76\u5bf9\u6574\u4f53III\u671f\u7814\u7a76\u63d0\u51fa\u4e86\u89c4\u5212\u4e0e\u671f\u5f85\u3002”\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230GFH375\u5df2\u7ecf\u5c55\u73b0\u4e86\u6cbb\u7597\u80f0\u817a\u764c\u7684\u5b89\u5168\u6027\u548c\u4f18\u79c0\u7597\u6548\uff0c\u4e5f\u611f\u53d7\u5230\u4e86\u60a3\u8005\u5bf9KRAS G12D\u9776\u5411\u7597\u6cd5\u4e0a\u5e02\u7684\u8feb\u5207\u671f\u5f85\u3002I\/II\u671f\u8bd5\u9a8c\u6210\u679c\u4e3aIII\u671f\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u575a\u5b9e\u7684\u57fa\u7840\uff0c\u4e5f\u8ba9\u5168\u56fd\u7814\u7a76\u8005\u6709\u4fe1\u5fc3\u63a8\u8fdbGFH375\u6ce8\u518c\u6027\u7814\u7a76\u3002\u6211\u4eec\u671f\u5f85\u4e0e\u2018\u764c\u4e2d\u4e4b\u738b’\u7684\u535a\u5f08\u5f81\u9014\u6d8c\u73b0\u65b0\u7684\u5e0c\u671b\uff0c\u4e5f\u671f\u5f85\u5411\u4e16\u754c\u5c55\u793a\u4f18\u79c0\u7684\u4e2d\u56fd\u521b\u65b0\u7597\u6cd5\uff0c\u4ee5\u836f\u4f01\u548c\u7814\u7a76\u8005\u7684\u5171\u540c\u52aa\u529b\u9020\u798f\u60a3\u8005\u4e0e\u793e\u4f1a\u3002” \u6b64\u5916\uff0c\u4f5c\u4e3a\u52b2\u65b9\u6b27\u6d32\u591a\u4e2d\u5fc3KROCUS\u7814\u7a76\uff08\u6c1f\u6cfd\u96f7\u585e\u8054\u5408\u897f\u59a5\u6614\u5355\u6297\u7684\u4e00\u7ebf\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u6848\uff09Leading PI\uff0cRafael Rosell\u6559\u6388\u4e5f\u5728\u524d\u671f\u6c9f\u901a\u4e2d\u8868\u793a\u5f88\u9ad8\u5174\u6210\u4e3a\u52b2\u65b9\u53e6\u4e00\u9879\u521b\u65b0\u7814\u7a76\u6307\u5bfc\u59d4\u5458\u4f1a\u7684\u5916\u90e8\u4e13\u5bb6\uff0c\u5e76\u4e3a\u8fd9\u9879\u91cd\u8981\u7814\u7a76\u8d21\u732e\u529b\u91cf\uff0c\u671f\u5f85\u4e0e\u59d4\u5458\u4f1a\u7684\u4e13\u5bb6\u548c\u6210\u5458\u5408\u4f5c\u3002 \u5415\u5f3a\u535a\u58eb\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u8868\u793a\u52b2\u65b9\u7531\u6d77\u5f52\u79d1\u5b66\u5bb6\u534f\u529b\u6253\u9020\u3001\u63a2\u7d22\u539f\u521b\u578b”\u5168\u7403\u65b0”\u836f\u7269\u5f00\u53d1\uff0c\u6210\u7acb\u4e03\u5e74\u540e\u8fce\u6765\u516c\u53f8\u9996\u4e2a\u4e0a\u5e02\u4ea7\u54c1\u6c1f\u6cfd\u96f7\u585e\uff08\u56fd\u5185\u9996\u6b3e\u3001\u5168\u7403\u7b2c\u4e09\u6b3e\u83b7\u6279\u7684KRAS G12C\u6291\u5236\u5242\uff09\uff0c\u5e76\u4ee5\u6c1f\u6cfd\u96f7\u585e\u7684\u7814\u53d1\u7ecf\u9a8c\u6253\u9020\u4e86\u4e00\u4f53\u5316RAS\u7597\u6cd5\u5f00\u53d1\u4f53\u7cfb\u3002”GFH375\u5728\u56fd\u5185\u4e34\u5e8a\u83b7\u6279\u540e\u4e09\u4e2a\u5b63\u5ea6\u5185\u8fdb\u5165II\u671f\u3001\u4e00\u5e74\u534a\u4e4b\u5185\u8fdb\u5165III\u671f\uff0c\u9ad8\u6548\u4e34\u5e8a\u8fdb\u5c55\u663e\u793a\u4e86\u52b2\u65b9\u901f\u5ea6\u548c\u4ea7\u54c1\u4f18\u6548\u3002GFH375\u662f\u52b2\u65b9RAS\u7597\u6cd5\u5f00\u53d1\u7684\u65b0\u8d77\u70b9\u2014\u2014\u516c\u53f8\u540e\u7eed\u7684\u591a\u5143\u5206\u5b50\u5f62\u6001RAS\u7597\u6cd5\uff0c\u5305\u62ec\u5168\u7403\u7b2c\u4e09\u6b3e\u4e34\u5e8a\u9636\u6bb5\u5206\u5b50\u80f6\u6cdbRAS\u6291\u5236\u5242GFH276\uff08I\/II\u671f\uff09\u3001\u5168\u7403\u9996\u6b3e\u6cdbRAS\u6297\u4f53\u5076\u8054\u836f\u7269GFS784\uff08IND\u53d7\u7406\uff09\uff0c\u8be5\u7cfb\u5217\u8fd8\u6709\u671b\u5f62\u6210\u534f\u540c\u6027\u80f0\u817a\u764c\u6cbb\u7597\u77e9\u9635\u3002\u672a\u6765\u52b2\u65b9\u5c06\u4ee5\u6301\u7eed\u63d0\u5347\u7684\u56fd\u9645\u7ade\u4e89\u529b\uff0c\u5851\u9020\u5168\u7403RAS\u8d5b\u9053\u7684\u9886\u5148\u4f01\u4e1a\uff0c\u8df5\u884c\u2018\u6025\u4e34\u5e8a\u672a\u7ade\u3001\u521b\u5168\u7403\u65b0\u836f’\u7684\u4f7f\u547d\u3002” \u9e92\u9e9f\u5c55”\u7ffc”\uff0c\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u65b0\u5f81\u7a0b \u80f0\u817a\u764c\u662f\u6076\u6027\u7a0b\u5ea6\u6700\u9ad8\u7684\u80bf\u7624\u4e4b\u4e00\u30015\u5e74\u751f\u5b58\u7387\u4f4e\u4e8e10%\uff0c\u76ee\u524d\u80f0\u817a\u764c\u7684\u4e00\u3001\u4e8c\u7ebf\u6807\u51c6\u6cbb\u7597\u5747\u4ee5\u5316\u7597\u4e3a\u4e3b\uff0c\u5c1a\u65e0\u8986\u76d6\u9762\u8f83\u5e7f\u7684\u76f8\u5173\u9776\u5411\u7597\u6cd5\u83b7\u6279\u4e0a\u5e02\u3002RAS\u7a81\u53d8\u5728\u80f0\u817a\u764c\u4e2d\u53d1\u751f\u7387\u9ad8\u8fbe90%\uff08KRAS G12D\u7a81\u53d8\u7387\u7ea640%\uff09\uff0cRAS\u901a\u8def\u7a81\u53d8\u53caTP53\u3001CDKN2A\u7b49\u5e38\u89c1\u5171\u7a81\u53d8\u662f\u5bfc\u81f4\u80f0\u817a\u764c\u53d1\u751f\u53d1\u5c55\u3001\u9884\u540e\u4e0d\u826f\u7684\u91cd\u8981\u56e0\u7d20\uff0cKRAS G12D\u7a81\u53d8\u66f4\u662f\u80f0\u817a\u764c\u7684\u72ec\u7acb\u9884\u540e\u4e0d\u826f\u6807\u5fd7\u3002\u65e2\u5f80\u7814\u7a76\u663e\u793a\uff0c\u76f8\u8f83\u4e8eKRAS\u91ce\u751f\u578b\u53ca\u5176\u4ed6KRAS\u7a81\u53d8\u4e9a\u578b\uff0cKRAS G12D\u7a81\u53d8\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08mRFS\uff09\u5747\u660e\u663e\u7f29\u77ed\u3002 \u8fd1\u5e74\u6765\u665a\u671f\u80f0\u817a\u764c\u4e34\u5e8a\u8bd5\u9a8c\uff08\u5305\u62ec\u4e00\u7ebf\u6cbb\u7597\uff09\u9879\u76ee\u4f17\u591a\uff0cKRAS G12D\u6291\u5236\u5242\u6210\u4e3a\u5f53\u524d\u80f0\u817a\u764c\u9776\u5411\u7597\u6cd5\u5f00\u53d1\u7684\u91cd\u8981\u65b9\u5411\u3002\u4f9d\u636eESMO\u53e3\u5934\u62a5\u544a\u62ab\u9732\u7684GFH375\u5355\u836f\u7597\u6cd5\u6570\u636e\uff0c\u8be5\u4ea7\u54c1\u5355\u836f\u6cbb\u7597\u80f0\u817a\u5bfc\u7ba1\u817a\u764c\uff08PDAC\uff09\u7684\u7597\u6548\u4e3a\u5168\u7403\u540c\u7c7b\u6700\u4f73\u3002\u76ee\u524dGFH375\/VS-7375\u5df2\u8fdb\u5165\u6cbb\u7597\u4e0d\u540c\u7624\u79cd\u7684\u591a\u4e2a\u56fd\u5185\u3001\u6d77\u5916\u5355\u836f\u53ca\u8054\u5408\u7597\u6cd5\u8bd5\u9a8c\uff0c\u5176\u4e2d\u52b2\u65b9\u5df2\u5728\u56fd\u5185\u5f00\u5c55GFH375\u8054\u5408\u5316\u7597\uff08AG\uff09\u4e00\u7ebf\u6cbb\u7597PDAC\u8bd5\u9a8c\uff1b\u4e14GFH375\/VS-7375\u5df2\u83b7\u5f97FDA\u5feb\u901f\u901a\u9053\u8d44\u683c\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5404\u7ebfKRAS G12D\u7a81\u53d8\u578b\u8f6c\u79fb\u6027PDAC\u3002\u6b64\u5916\uff0cGFH375\u5355\u836f\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u7597\u6548\u53ca\u603b\u4f53\u5f00\u53d1\u8fdb\u5ea6\uff0c\u4e5f\u5728\u5168\u7403KRAS G12D\u9776\u5411\u7597\u6cd5\u4e2d\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002 \u52b2\u65b9\u4e34\u5e8a\u56e2\u961f\u5728\u5927\u4f1a\u4e2d\u4ecb\u7ecd\u4e86III\u671f\u7814\u7a76\u7684\u65b9\u6848\u8bbe\u8ba1\u3001\u5165\u7ec4\u6807\u51c6\u3001\u6709\u6548\u6027\u8bc4\u4f30\u53ca\u5408\u5e76\u7528\u836f\u7b49\u5185\u5bb9\u3002\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u5468\u519b\u6559\u6388\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u674e\u82f1\u6559\u6388\u3001\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u674e\u5fd7\u4f1f\u6559\u6388\u3001\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\u5468\u9896\u73c2\u526f\u6559\u6388\u7b49\u7814\u7a76\u4e13\u5bb6\uff0c\u5728\u73b0\u573a\u6f14\u8bb2\u4e2d\u5206\u4eab\u4e86GFH375\u80f0\u817a\u764c\u6cbb\u7597\u5b9e\u8df5\u7684\u6848\u4f8b\u5206\u6790\u548c\u5b9d\u8d35\u7ecf\u9a8c\u3002\u4e0e\u4f1a\u8005\u9488\u5bf9\u6b64\u9879\u7814\u7a76\u7684\u8fdb\u5ea6\u89c4\u5212\u3001\u9879\u76ee\u7ec6\u8282\u3001\u5168\u56fd\u5404\u7814\u7a76\u4e2d\u5fc3\u7684\u6c9f\u901a\u534f\u4f5c\u7b49\u8bdd\u9898\u8fdb\u884c\u4e86\u5145\u5206\u8ba8\u8bba\uff0c\u5927\u5bb6\u671f\u5f85\u901a\u8fc7\u4ea7\u4e1a\u4e0e\u533b\u5b66\u754c\u7684\u643a\u624b\u5171\u8fdb\uff0c\u63a8\u8fdb”\u9e92\u9e9f-\u7ffc01″\u7814\u7a76\u8fdb\u5c55\u5e76\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u8fc8\u5411\u5e02\u573a\u3002 \u5173\u4e8e\u52b2\u65b9\u533b\u836f \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u662f\u4e00\u5bb6\u5168\u7403\u5e03\u5c40\u7684\u521b\u65b0\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\uff0c\u805a\u7126\u80bf\u7624\u3001\u514d\u75ab\u7c7b\u75be\u75c5\u9886\u57df\u9ad8\u5ea6\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u4ee5\u75be\u75c5\u751f\u7269\u5b66\u673a\u7406\u548c\u4e34\u5e8a\u8f6c\u5316\u533b\u5b66\u4e3a\u6838\u5fc3\uff0c\u6784\u5efa\u5e76\u53d1\u6325\u81ea\u4e3b\u5316\u3001\u4e00\u4f53\u5316\u7814\u53d1\u4f53\u7cfb\u4f18\u52bf\uff0c\u4e3b\u653b\u5c1a\u65e0\u4e34\u5e8a\u9a8c\u8bc1\u7684\u521b\u65b0\u9776\u70b9\u4e0e\u9002\u5e94\u75c7\uff0c\u5e76\u62e5\u6709\u5168\u7403\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u3002\u81ea2017\u5e74\u6210\u7acb\u4ee5\u6765\uff0c\u52b2\u65b9\u533b\u836f\u5df2\u5efa\u7acb\u5305\u542b\u591a\u4e2a\u81ea\u4e3b\u7814\u53d1\u7684”\u5168\u7403\u65b0”\u5927\u3001\u5c0f\u5206\u5b50\u9879\u76ee\uff0c\u591a\u4e2a\u4ea7\u54c1\u5728\u4e2d\u56fd\u3001\u6b27\u6d32\u3001\u7f8e\u56fd\u8fdb\u5165\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5305\u62ec\u591a\u9879\u540e\u671f\u6216\u5173\u952e\u6027\u4e34\u5e8a\u7814\u7a76\u3002 \u8fbe\u4f2f\u7279\u00ae\uff08\u6c1f\u6cfd\u96f7\u585e\uff09\u4e3a\u52b2\u65b9\u7ba1\u7ebf\u4e2d\u9996\u4e2a\u56fd\u5185\u4e0a\u5e02\u83b7\u6279\u4ea7\u54c1\uff0c\u4e5f\u662f\u56fd\u5185\u9996\u4e2a\u3001\u5168\u7403\u7b2c\u4e09\u4e2a\u4e0a\u5e02\u7684KRAS G12C\u6291\u5236\u5242\uff1b\u76ee\u524d\u516c\u53f8\u5df2\u5f62\u6210RAS\u9776\u5411\u7597\u6cd5\u7684\u4e00\u4f53\u5316\u6df1\u8015\u77e9\u9635\uff0c\u5305\u62ec\u591a\u9776\u70b9\u3001\u591a\u79cd\u5206\u5b50\u7c7b\u578b\u7684\u9009\u62e9\u6027\u53ca\u6cdbRAS\u6291\u5236\u5242\uff0c\u591a\u4e2a\u4ea7\u54c1\u5f00\u53d1\u8fdb\u5ea6\u5728\u56fd\u5185\u5916\u540c\u9776\u70b9\u8d5b\u9053\u5904\u4e8e\u9886\u5148\uff0c\u4e14\u7814\u7a76\u6570\u636e\u591a\u6b21\u767b\u9646\u56fd\u9645\u5b66\u672f\u4f1a\u8bae\u7a81\u7834\u6027\u7814\u7a76\u6458\u8981\u53ca\u53e3\u5934\u62a5\u544a\u3002\u540c\u65f6\uff0c\u516c\u53f8\u79ef\u6781\u62d3\u5c55\u5176\u4ed6”\u5168\u7403\u65b0”\u9776\u5411\u836f\u5f00\u53d1\uff0c\u91c7\u7528\u534f\u540c\u673a\u5236\u6253\u9020\u5168\u7403\u9996\u521b\u7684\u591a\u7c7b\u578b\u53cc\u9776\u70b9\u7597\u6cd5\uff1b\u5e76\u7ed3\u5408\u4e34\u5e8a\u9700\u6c42\u4e0e\u6cbb\u7597\u7406\u5ff5\u7684\u521b\u65b0\uff0c\u4ee5\u4ea7\u54c1\u77e9\u9635\u8fdb\u519b\u80f0\u817a\u764c\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u6076\u75c5\u8d28\u7b49\u5927\u9002\u5e94\u75c7\u5e02\u573a\u3002 \u52b2\u65b9\u5df2\u83b7\u5f97\u56fd\u5bb6\u7ea7\u4e13\u7cbe\u7279\u65b0”\u5c0f\u5de8\u4eba”\u3001\u56fd\u5bb6\u7ea7\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u79f0\u53f7\uff0c\u5e76\u83b7\u5f97\u4e0a\u6d77\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u3001\u4e0a\u6d77\u5e02\u8de8\u56fd\u516c\u53f8\u7814\u53d1\u4e2d\u5fc3\u3001\u4e0a\u6d77\u5e02\u4f01\u4e1a\u6280\u672f\u4e2d\u5fc3\u8ba4\u5b9a\u3002\u516c\u53f8\u8fd1\u5e74\u6765\u4e0d\u65ad\u6df1\u5316\u5546\u4e1a\u5408\u4f5c\u7f51\u7edc\uff0c\u5df2\u4e0e\u591a\u4e2a\u5883\u5185\u5916\u4e0a\u5e02\u516c\u53f8\u8fbe\u6210\u6218\u7565\u6388\u6743\u534f\u8bae\u3001\u6216\u5f00\u5c55”\u5168\u7403\u65b0”\u4e34\u5e8a\u5408\u4f5c\u5e76\u5df2\u53d6\u5f97\u79ef\u6781\u8fdb\u5c55\u3002 \u00a0 SOURCE \u52b2\u65b9\u533b\u836f<\/p>\n","protected":false},"author":0,"featured_media":21668,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-21667","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\n\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76("\u9e92\u9e9f-\u7ffc01")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014-\u52b2\u65b9gfh375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764ciii\u671f\u7814\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76("\u9e92\u9e9f-\u7ffc01")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"\u4e0a\u6d772026\u5e742\u670812\u65e5 \/\u7f8e\u901a\u793e\/ — \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u8fd1\u65e5\u6210\u529f\u53ec\u5f00GFH375\uff08\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff09III\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u3002\u6b64\u9879\u7814\u7a76\uff08GFH375X1301\uff0c\u9e92\u9e9f-\u7ffc01\uff09\u4e8e2025\u5e7411\u6708\u5728\u9996\u5bb6\u4e2d\u5fc3\u542f\u52a8\uff0c\u9488\u5bf9\u80f0\u817a\u764cKRAS\u7a81\u53d8\u5360\u6bd4\u6700\u9ad8\u7684G12D\u7a81\u53d8\u578b\u60a3\u8005\u5f00\u5c55\uff0c\u4e3a\u5168\u7403\u9996\u4e2a\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u7684III\u671f\u7814\u7a76\u3002\u6765\u81ea\u5168\u56fd\u7684\u6570\u5341\u5bb6\u7814\u7a76\u4e2d\u5fc3\u4e13\u5bb6\u4ee3\u8868\u9f50\u805a\u5317\u4eac\uff0c\u56f4\u7ed5\u9879\u76ee\u7684\u65e2\u5f80\u5165\u7ec4\u7ecf\u9a8c\u3001\u6cbb\u7597\u6548\u679c\u3001\u4ee5\u53ca\u540e\u7eed\u9879\u76ee\u7ba1\u7406\u8fdb\u884c\u6df1\u5ea6\u4ea4\u6d41\u3002 \u8be5\u7814\u7a76\u7275\u5934\u5355\u4f4d\u4e3a\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff0c\u9879\u76ee\u5c06\u5728\u8d85\u8fc740\u5bb6\u7814\u7a76\u4e2d\u5fc3\u5f00\u5c55\u3001\u8ba1\u5212\u5165\u7ec4\u6570\u767e\u4f8b\u65e2\u5f80\u63a5\u53d7\u81f3\u5c11\u4e00\u79cd\u6807\u51c6\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u80f0\u817a\u764c\u60a3\u8005\uff1b\u8be5\u8bd5\u9a8c\u6307\u5bfc\u59d4\u5458\u4f1a\u5916\u90e8\u4e13\u5bb6\u5305\u62ec\u5317\u4eac\u534f\u548c\u533b\u9662\u540d\u8a89\u9662\u957f\u8d75\u7389\u6c9b\u9662\u58eb\u3001\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3Dexeus\u5927\u5b66\u533b\u9662Rafael Rosell\u6559\u6388\u53ca\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u6c88\u7433\u6559\u6388\u3002 \u653b\u575a”\u764c\u4e2d\u4e4b\u738b”\uff0c\u6784\u5efaRAS\u8d5b\u9053\u5934\u90e8\u4f01\u4e1a\u4f18\u52bf \u52b2\u65b9\u533b\u836f\u8463\u4e8b\u957f\u5415\u5f3a\u535a\u58eb\u5f00\u573a\u65f6\u8f6c\u8fbe\u4e86\u8d75\u7389\u6c9b\u9662\u58eb\u7684\u4e66\u9762\u8d3a\u8f9e\uff0c\u663e\u793a\u4e86\u5176\u5bf9\u8bd5\u9a8c\u5f00\u5c55\u7684\u671f\u5f85\u548c\u4fe1\u5fc3\u3002”GFH375\u662f\u5168\u7403\u9996\u4e2a\u8fdb\u5165\u4e09\u671f\u8bd5\u9a8c\u7684\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff0c\u8fd9\u9879\u7814\u7a76\u5bf9\u80f0\u817a\u764c\u7684\u6cbb\u7597\u5177\u6709\u6f5c\u5728\u7684\u7a81\u7834\u610f\u4e49\u3002\u5e0c\u671b\u5404\u4f4d\u7814\u7a76\u8005\u5728\u8fd9\u9879\u4e09\u671f\u8bd5\u9a8c\u4e2d\u901a\u529b\u5408\u4f5c\uff0c\u4e3a\u4e2d\u56fd\u80fd\u591f\u9886\u5148\u4e16\u754c\u80f0\u817a\u75c5\u4e34\u5e8a\u7814\u7a76\u505a\u51fa\u4e00\u4efd\u8d21\u732e\u3002\u611f\u8c22\u52b2\u65b9\u533b\u836f\u7684\u52aa\u529b\u548c\u5949\u732e\uff0c\u9884\u795d\u8be5\u8bd5\u9a8c\u53d6\u5f97\u7406\u60f3\u6210\u679c\uff01” \u6b64\u9879\u7814\u7a76\u7684Leading PI\u6c88\u7433\u6559\u6388\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u56de\u987e\u4e86GFH375\u5728\u524d\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u7814\u7a76\u6210\u679c\uff0c\u5e76\u5bf9\u6574\u4f53III\u671f\u7814\u7a76\u63d0\u51fa\u4e86\u89c4\u5212\u4e0e\u671f\u5f85\u3002”\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230GFH375\u5df2\u7ecf\u5c55\u73b0\u4e86\u6cbb\u7597\u80f0\u817a\u764c\u7684\u5b89\u5168\u6027\u548c\u4f18\u79c0\u7597\u6548\uff0c\u4e5f\u611f\u53d7\u5230\u4e86\u60a3\u8005\u5bf9KRAS G12D\u9776\u5411\u7597\u6cd5\u4e0a\u5e02\u7684\u8feb\u5207\u671f\u5f85\u3002I\/II\u671f\u8bd5\u9a8c\u6210\u679c\u4e3aIII\u671f\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u575a\u5b9e\u7684\u57fa\u7840\uff0c\u4e5f\u8ba9\u5168\u56fd\u7814\u7a76\u8005\u6709\u4fe1\u5fc3\u63a8\u8fdbGFH375\u6ce8\u518c\u6027\u7814\u7a76\u3002\u6211\u4eec\u671f\u5f85\u4e0e\u2018\u764c\u4e2d\u4e4b\u738b’\u7684\u535a\u5f08\u5f81\u9014\u6d8c\u73b0\u65b0\u7684\u5e0c\u671b\uff0c\u4e5f\u671f\u5f85\u5411\u4e16\u754c\u5c55\u793a\u4f18\u79c0\u7684\u4e2d\u56fd\u521b\u65b0\u7597\u6cd5\uff0c\u4ee5\u836f\u4f01\u548c\u7814\u7a76\u8005\u7684\u5171\u540c\u52aa\u529b\u9020\u798f\u60a3\u8005\u4e0e\u793e\u4f1a\u3002” \u6b64\u5916\uff0c\u4f5c\u4e3a\u52b2\u65b9\u6b27\u6d32\u591a\u4e2d\u5fc3KROCUS\u7814\u7a76\uff08\u6c1f\u6cfd\u96f7\u585e\u8054\u5408\u897f\u59a5\u6614\u5355\u6297\u7684\u4e00\u7ebf\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u6848\uff09Leading PI\uff0cRafael Rosell\u6559\u6388\u4e5f\u5728\u524d\u671f\u6c9f\u901a\u4e2d\u8868\u793a\u5f88\u9ad8\u5174\u6210\u4e3a\u52b2\u65b9\u53e6\u4e00\u9879\u521b\u65b0\u7814\u7a76\u6307\u5bfc\u59d4\u5458\u4f1a\u7684\u5916\u90e8\u4e13\u5bb6\uff0c\u5e76\u4e3a\u8fd9\u9879\u91cd\u8981\u7814\u7a76\u8d21\u732e\u529b\u91cf\uff0c\u671f\u5f85\u4e0e\u59d4\u5458\u4f1a\u7684\u4e13\u5bb6\u548c\u6210\u5458\u5408\u4f5c\u3002 \u5415\u5f3a\u535a\u58eb\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u8868\u793a\u52b2\u65b9\u7531\u6d77\u5f52\u79d1\u5b66\u5bb6\u534f\u529b\u6253\u9020\u3001\u63a2\u7d22\u539f\u521b\u578b”\u5168\u7403\u65b0”\u836f\u7269\u5f00\u53d1\uff0c\u6210\u7acb\u4e03\u5e74\u540e\u8fce\u6765\u516c\u53f8\u9996\u4e2a\u4e0a\u5e02\u4ea7\u54c1\u6c1f\u6cfd\u96f7\u585e\uff08\u56fd\u5185\u9996\u6b3e\u3001\u5168\u7403\u7b2c\u4e09\u6b3e\u83b7\u6279\u7684KRAS G12C\u6291\u5236\u5242\uff09\uff0c\u5e76\u4ee5\u6c1f\u6cfd\u96f7\u585e\u7684\u7814\u53d1\u7ecf\u9a8c\u6253\u9020\u4e86\u4e00\u4f53\u5316RAS\u7597\u6cd5\u5f00\u53d1\u4f53\u7cfb\u3002”GFH375\u5728\u56fd\u5185\u4e34\u5e8a\u83b7\u6279\u540e\u4e09\u4e2a\u5b63\u5ea6\u5185\u8fdb\u5165II\u671f\u3001\u4e00\u5e74\u534a\u4e4b\u5185\u8fdb\u5165III\u671f\uff0c\u9ad8\u6548\u4e34\u5e8a\u8fdb\u5c55\u663e\u793a\u4e86\u52b2\u65b9\u901f\u5ea6\u548c\u4ea7\u54c1\u4f18\u6548\u3002GFH375\u662f\u52b2\u65b9RAS\u7597\u6cd5\u5f00\u53d1\u7684\u65b0\u8d77\u70b9\u2014\u2014\u516c\u53f8\u540e\u7eed\u7684\u591a\u5143\u5206\u5b50\u5f62\u6001RAS\u7597\u6cd5\uff0c\u5305\u62ec\u5168\u7403\u7b2c\u4e09\u6b3e\u4e34\u5e8a\u9636\u6bb5\u5206\u5b50\u80f6\u6cdbRAS\u6291\u5236\u5242GFH276\uff08I\/II\u671f\uff09\u3001\u5168\u7403\u9996\u6b3e\u6cdbRAS\u6297\u4f53\u5076\u8054\u836f\u7269GFS784\uff08IND\u53d7\u7406\uff09\uff0c\u8be5\u7cfb\u5217\u8fd8\u6709\u671b\u5f62\u6210\u534f\u540c\u6027\u80f0\u817a\u764c\u6cbb\u7597\u77e9\u9635\u3002\u672a\u6765\u52b2\u65b9\u5c06\u4ee5\u6301\u7eed\u63d0\u5347\u7684\u56fd\u9645\u7ade\u4e89\u529b\uff0c\u5851\u9020\u5168\u7403RAS\u8d5b\u9053\u7684\u9886\u5148\u4f01\u4e1a\uff0c\u8df5\u884c\u2018\u6025\u4e34\u5e8a\u672a\u7ade\u3001\u521b\u5168\u7403\u65b0\u836f’\u7684\u4f7f\u547d\u3002” \u9e92\u9e9f\u5c55”\u7ffc”\uff0c\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u65b0\u5f81\u7a0b \u80f0\u817a\u764c\u662f\u6076\u6027\u7a0b\u5ea6\u6700\u9ad8\u7684\u80bf\u7624\u4e4b\u4e00\u30015\u5e74\u751f\u5b58\u7387\u4f4e\u4e8e10%\uff0c\u76ee\u524d\u80f0\u817a\u764c\u7684\u4e00\u3001\u4e8c\u7ebf\u6807\u51c6\u6cbb\u7597\u5747\u4ee5\u5316\u7597\u4e3a\u4e3b\uff0c\u5c1a\u65e0\u8986\u76d6\u9762\u8f83\u5e7f\u7684\u76f8\u5173\u9776\u5411\u7597\u6cd5\u83b7\u6279\u4e0a\u5e02\u3002RAS\u7a81\u53d8\u5728\u80f0\u817a\u764c\u4e2d\u53d1\u751f\u7387\u9ad8\u8fbe90%\uff08KRAS G12D\u7a81\u53d8\u7387\u7ea640%\uff09\uff0cRAS\u901a\u8def\u7a81\u53d8\u53caTP53\u3001CDKN2A\u7b49\u5e38\u89c1\u5171\u7a81\u53d8\u662f\u5bfc\u81f4\u80f0\u817a\u764c\u53d1\u751f\u53d1\u5c55\u3001\u9884\u540e\u4e0d\u826f\u7684\u91cd\u8981\u56e0\u7d20\uff0cKRAS G12D\u7a81\u53d8\u66f4\u662f\u80f0\u817a\u764c\u7684\u72ec\u7acb\u9884\u540e\u4e0d\u826f\u6807\u5fd7\u3002\u65e2\u5f80\u7814\u7a76\u663e\u793a\uff0c\u76f8\u8f83\u4e8eKRAS\u91ce\u751f\u578b\u53ca\u5176\u4ed6KRAS\u7a81\u53d8\u4e9a\u578b\uff0cKRAS G12D\u7a81\u53d8\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08mRFS\uff09\u5747\u660e\u663e\u7f29\u77ed\u3002 \u8fd1\u5e74\u6765\u665a\u671f\u80f0\u817a\u764c\u4e34\u5e8a\u8bd5\u9a8c\uff08\u5305\u62ec\u4e00\u7ebf\u6cbb\u7597\uff09\u9879\u76ee\u4f17\u591a\uff0cKRAS G12D\u6291\u5236\u5242\u6210\u4e3a\u5f53\u524d\u80f0\u817a\u764c\u9776\u5411\u7597\u6cd5\u5f00\u53d1\u7684\u91cd\u8981\u65b9\u5411\u3002\u4f9d\u636eESMO\u53e3\u5934\u62a5\u544a\u62ab\u9732\u7684GFH375\u5355\u836f\u7597\u6cd5\u6570\u636e\uff0c\u8be5\u4ea7\u54c1\u5355\u836f\u6cbb\u7597\u80f0\u817a\u5bfc\u7ba1\u817a\u764c\uff08PDAC\uff09\u7684\u7597\u6548\u4e3a\u5168\u7403\u540c\u7c7b\u6700\u4f73\u3002\u76ee\u524dGFH375\/VS-7375\u5df2\u8fdb\u5165\u6cbb\u7597\u4e0d\u540c\u7624\u79cd\u7684\u591a\u4e2a\u56fd\u5185\u3001\u6d77\u5916\u5355\u836f\u53ca\u8054\u5408\u7597\u6cd5\u8bd5\u9a8c\uff0c\u5176\u4e2d\u52b2\u65b9\u5df2\u5728\u56fd\u5185\u5f00\u5c55GFH375\u8054\u5408\u5316\u7597\uff08AG\uff09\u4e00\u7ebf\u6cbb\u7597PDAC\u8bd5\u9a8c\uff1b\u4e14GFH375\/VS-7375\u5df2\u83b7\u5f97FDA\u5feb\u901f\u901a\u9053\u8d44\u683c\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5404\u7ebfKRAS G12D\u7a81\u53d8\u578b\u8f6c\u79fb\u6027PDAC\u3002\u6b64\u5916\uff0cGFH375\u5355\u836f\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u7597\u6548\u53ca\u603b\u4f53\u5f00\u53d1\u8fdb\u5ea6\uff0c\u4e5f\u5728\u5168\u7403KRAS G12D\u9776\u5411\u7597\u6cd5\u4e2d\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002 \u52b2\u65b9\u4e34\u5e8a\u56e2\u961f\u5728\u5927\u4f1a\u4e2d\u4ecb\u7ecd\u4e86III\u671f\u7814\u7a76\u7684\u65b9\u6848\u8bbe\u8ba1\u3001\u5165\u7ec4\u6807\u51c6\u3001\u6709\u6548\u6027\u8bc4\u4f30\u53ca\u5408\u5e76\u7528\u836f\u7b49\u5185\u5bb9\u3002\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u5468\u519b\u6559\u6388\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u674e\u82f1\u6559\u6388\u3001\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u674e\u5fd7\u4f1f\u6559\u6388\u3001\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\u5468\u9896\u73c2\u526f\u6559\u6388\u7b49\u7814\u7a76\u4e13\u5bb6\uff0c\u5728\u73b0\u573a\u6f14\u8bb2\u4e2d\u5206\u4eab\u4e86GFH375\u80f0\u817a\u764c\u6cbb\u7597\u5b9e\u8df5\u7684\u6848\u4f8b\u5206\u6790\u548c\u5b9d\u8d35\u7ecf\u9a8c\u3002\u4e0e\u4f1a\u8005\u9488\u5bf9\u6b64\u9879\u7814\u7a76\u7684\u8fdb\u5ea6\u89c4\u5212\u3001\u9879\u76ee\u7ec6\u8282\u3001\u5168\u56fd\u5404\u7814\u7a76\u4e2d\u5fc3\u7684\u6c9f\u901a\u534f\u4f5c\u7b49\u8bdd\u9898\u8fdb\u884c\u4e86\u5145\u5206\u8ba8\u8bba\uff0c\u5927\u5bb6\u671f\u5f85\u901a\u8fc7\u4ea7\u4e1a\u4e0e\u533b\u5b66\u754c\u7684\u643a\u624b\u5171\u8fdb\uff0c\u63a8\u8fdb”\u9e92\u9e9f-\u7ffc01″\u7814\u7a76\u8fdb\u5c55\u5e76\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u8fc8\u5411\u5e02\u573a\u3002 \u5173\u4e8e\u52b2\u65b9\u533b\u836f \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u662f\u4e00\u5bb6\u5168\u7403\u5e03\u5c40\u7684\u521b\u65b0\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\uff0c\u805a\u7126\u80bf\u7624\u3001\u514d\u75ab\u7c7b\u75be\u75c5\u9886\u57df\u9ad8\u5ea6\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u4ee5\u75be\u75c5\u751f\u7269\u5b66\u673a\u7406\u548c\u4e34\u5e8a\u8f6c\u5316\u533b\u5b66\u4e3a\u6838\u5fc3\uff0c\u6784\u5efa\u5e76\u53d1\u6325\u81ea\u4e3b\u5316\u3001\u4e00\u4f53\u5316\u7814\u53d1\u4f53\u7cfb\u4f18\u52bf\uff0c\u4e3b\u653b\u5c1a\u65e0\u4e34\u5e8a\u9a8c\u8bc1\u7684\u521b\u65b0\u9776\u70b9\u4e0e\u9002\u5e94\u75c7\uff0c\u5e76\u62e5\u6709\u5168\u7403\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u3002\u81ea2017\u5e74\u6210\u7acb\u4ee5\u6765\uff0c\u52b2\u65b9\u533b\u836f\u5df2\u5efa\u7acb\u5305\u542b\u591a\u4e2a\u81ea\u4e3b\u7814\u53d1\u7684”\u5168\u7403\u65b0”\u5927\u3001\u5c0f\u5206\u5b50\u9879\u76ee\uff0c\u591a\u4e2a\u4ea7\u54c1\u5728\u4e2d\u56fd\u3001\u6b27\u6d32\u3001\u7f8e\u56fd\u8fdb\u5165\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5305\u62ec\u591a\u9879\u540e\u671f\u6216\u5173\u952e\u6027\u4e34\u5e8a\u7814\u7a76\u3002 \u8fbe\u4f2f\u7279\u00ae\uff08\u6c1f\u6cfd\u96f7\u585e\uff09\u4e3a\u52b2\u65b9\u7ba1\u7ebf\u4e2d\u9996\u4e2a\u56fd\u5185\u4e0a\u5e02\u83b7\u6279\u4ea7\u54c1\uff0c\u4e5f\u662f\u56fd\u5185\u9996\u4e2a\u3001\u5168\u7403\u7b2c\u4e09\u4e2a\u4e0a\u5e02\u7684KRAS G12C\u6291\u5236\u5242\uff1b\u76ee\u524d\u516c\u53f8\u5df2\u5f62\u6210RAS\u9776\u5411\u7597\u6cd5\u7684\u4e00\u4f53\u5316\u6df1\u8015\u77e9\u9635\uff0c\u5305\u62ec\u591a\u9776\u70b9\u3001\u591a\u79cd\u5206\u5b50\u7c7b\u578b\u7684\u9009\u62e9\u6027\u53ca\u6cdbRAS\u6291\u5236\u5242\uff0c\u591a\u4e2a\u4ea7\u54c1\u5f00\u53d1\u8fdb\u5ea6\u5728\u56fd\u5185\u5916\u540c\u9776\u70b9\u8d5b\u9053\u5904\u4e8e\u9886\u5148\uff0c\u4e14\u7814\u7a76\u6570\u636e\u591a\u6b21\u767b\u9646\u56fd\u9645\u5b66\u672f\u4f1a\u8bae\u7a81\u7834\u6027\u7814\u7a76\u6458\u8981\u53ca\u53e3\u5934\u62a5\u544a\u3002\u540c\u65f6\uff0c\u516c\u53f8\u79ef\u6781\u62d3\u5c55\u5176\u4ed6”\u5168\u7403\u65b0”\u9776\u5411\u836f\u5f00\u53d1\uff0c\u91c7\u7528\u534f\u540c\u673a\u5236\u6253\u9020\u5168\u7403\u9996\u521b\u7684\u591a\u7c7b\u578b\u53cc\u9776\u70b9\u7597\u6cd5\uff1b\u5e76\u7ed3\u5408\u4e34\u5e8a\u9700\u6c42\u4e0e\u6cbb\u7597\u7406\u5ff5\u7684\u521b\u65b0\uff0c\u4ee5\u4ea7\u54c1\u77e9\u9635\u8fdb\u519b\u80f0\u817a\u764c\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u6076\u75c5\u8d28\u7b49\u5927\u9002\u5e94\u75c7\u5e02\u573a\u3002 \u52b2\u65b9\u5df2\u83b7\u5f97\u56fd\u5bb6\u7ea7\u4e13\u7cbe\u7279\u65b0”\u5c0f\u5de8\u4eba”\u3001\u56fd\u5bb6\u7ea7\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u79f0\u53f7\uff0c\u5e76\u83b7\u5f97\u4e0a\u6d77\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u3001\u4e0a\u6d77\u5e02\u8de8\u56fd\u516c\u53f8\u7814\u53d1\u4e2d\u5fc3\u3001\u4e0a\u6d77\u5e02\u4f01\u4e1a\u6280\u672f\u4e2d\u5fc3\u8ba4\u5b9a\u3002\u516c\u53f8\u8fd1\u5e74\u6765\u4e0d\u65ad\u6df1\u5316\u5546\u4e1a\u5408\u4f5c\u7f51\u7edc\uff0c\u5df2\u4e0e\u591a\u4e2a\u5883\u5185\u5916\u4e0a\u5e02\u516c\u53f8\u8fbe\u6210\u6218\u7565\u6388\u6743\u534f\u8bae\u3001\u6216\u5f00\u5c55”\u5168\u7403\u65b0”\u4e34\u5e8a\u5408\u4f5c\u5e76\u5df2\u53d6\u5f97\u79ef\u6781\u8fdb\u5c55\u3002 \u00a0 SOURCE \u52b2\u65b9\u533b\u836f\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014-\u52b2\u65b9gfh375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764ciii\u671f\u7814\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-12T00:15:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/\",\"name\":\"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(\\\"\u9e92\u9e9f-\u7ffc01\\\")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN\",\"isPartOf\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg\",\"datePublished\":\"2026-02-12T00:15:00+00:00\",\"dateModified\":\"2026-02-12T00:15:00+00:00\",\"author\":{\"@id\":\"\"},\"breadcrumb\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg\",\"contentUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg\",\"width\":144,\"height\":96},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/moneycompass.com.my\/cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(“\u9e92\u9e9f-\u7ffc01”)\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/\",\"name\":\"Money Compass CN\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(\"\u9e92\u9e9f-\u7ffc01\")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/moneycompass.com.my\/cn\/\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014-\u52b2\u65b9gfh375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764ciii\u671f\u7814\/","og_locale":"en_US","og_type":"article","og_title":"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(\"\u9e92\u9e9f-\u7ffc01\")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN","og_description":"\u4e0a\u6d772026\u5e742\u670812\u65e5 \/\u7f8e\u901a\u793e\/ — \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u8fd1\u65e5\u6210\u529f\u53ec\u5f00GFH375\uff08\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff09III\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u3002\u6b64\u9879\u7814\u7a76\uff08GFH375X1301\uff0c\u9e92\u9e9f-\u7ffc01\uff09\u4e8e2025\u5e7411\u6708\u5728\u9996\u5bb6\u4e2d\u5fc3\u542f\u52a8\uff0c\u9488\u5bf9\u80f0\u817a\u764cKRAS\u7a81\u53d8\u5360\u6bd4\u6700\u9ad8\u7684G12D\u7a81\u53d8\u578b\u60a3\u8005\u5f00\u5c55\uff0c\u4e3a\u5168\u7403\u9996\u4e2a\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u7684III\u671f\u7814\u7a76\u3002\u6765\u81ea\u5168\u56fd\u7684\u6570\u5341\u5bb6\u7814\u7a76\u4e2d\u5fc3\u4e13\u5bb6\u4ee3\u8868\u9f50\u805a\u5317\u4eac\uff0c\u56f4\u7ed5\u9879\u76ee\u7684\u65e2\u5f80\u5165\u7ec4\u7ecf\u9a8c\u3001\u6cbb\u7597\u6548\u679c\u3001\u4ee5\u53ca\u540e\u7eed\u9879\u76ee\u7ba1\u7406\u8fdb\u884c\u6df1\u5ea6\u4ea4\u6d41\u3002 \u8be5\u7814\u7a76\u7275\u5934\u5355\u4f4d\u4e3a\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff0c\u9879\u76ee\u5c06\u5728\u8d85\u8fc740\u5bb6\u7814\u7a76\u4e2d\u5fc3\u5f00\u5c55\u3001\u8ba1\u5212\u5165\u7ec4\u6570\u767e\u4f8b\u65e2\u5f80\u63a5\u53d7\u81f3\u5c11\u4e00\u79cd\u6807\u51c6\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u80f0\u817a\u764c\u60a3\u8005\uff1b\u8be5\u8bd5\u9a8c\u6307\u5bfc\u59d4\u5458\u4f1a\u5916\u90e8\u4e13\u5bb6\u5305\u62ec\u5317\u4eac\u534f\u548c\u533b\u9662\u540d\u8a89\u9662\u957f\u8d75\u7389\u6c9b\u9662\u58eb\u3001\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3Dexeus\u5927\u5b66\u533b\u9662Rafael Rosell\u6559\u6388\u53ca\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u6c88\u7433\u6559\u6388\u3002 \u653b\u575a”\u764c\u4e2d\u4e4b\u738b”\uff0c\u6784\u5efaRAS\u8d5b\u9053\u5934\u90e8\u4f01\u4e1a\u4f18\u52bf \u52b2\u65b9\u533b\u836f\u8463\u4e8b\u957f\u5415\u5f3a\u535a\u58eb\u5f00\u573a\u65f6\u8f6c\u8fbe\u4e86\u8d75\u7389\u6c9b\u9662\u58eb\u7684\u4e66\u9762\u8d3a\u8f9e\uff0c\u663e\u793a\u4e86\u5176\u5bf9\u8bd5\u9a8c\u5f00\u5c55\u7684\u671f\u5f85\u548c\u4fe1\u5fc3\u3002”GFH375\u662f\u5168\u7403\u9996\u4e2a\u8fdb\u5165\u4e09\u671f\u8bd5\u9a8c\u7684\u53e3\u670dKRAS G12D\u6291\u5236\u5242\uff0c\u8fd9\u9879\u7814\u7a76\u5bf9\u80f0\u817a\u764c\u7684\u6cbb\u7597\u5177\u6709\u6f5c\u5728\u7684\u7a81\u7834\u610f\u4e49\u3002\u5e0c\u671b\u5404\u4f4d\u7814\u7a76\u8005\u5728\u8fd9\u9879\u4e09\u671f\u8bd5\u9a8c\u4e2d\u901a\u529b\u5408\u4f5c\uff0c\u4e3a\u4e2d\u56fd\u80fd\u591f\u9886\u5148\u4e16\u754c\u80f0\u817a\u75c5\u4e34\u5e8a\u7814\u7a76\u505a\u51fa\u4e00\u4efd\u8d21\u732e\u3002\u611f\u8c22\u52b2\u65b9\u533b\u836f\u7684\u52aa\u529b\u548c\u5949\u732e\uff0c\u9884\u795d\u8be5\u8bd5\u9a8c\u53d6\u5f97\u7406\u60f3\u6210\u679c\uff01” \u6b64\u9879\u7814\u7a76\u7684Leading PI\u6c88\u7433\u6559\u6388\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u56de\u987e\u4e86GFH375\u5728\u524d\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u7814\u7a76\u6210\u679c\uff0c\u5e76\u5bf9\u6574\u4f53III\u671f\u7814\u7a76\u63d0\u51fa\u4e86\u89c4\u5212\u4e0e\u671f\u5f85\u3002”\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230GFH375\u5df2\u7ecf\u5c55\u73b0\u4e86\u6cbb\u7597\u80f0\u817a\u764c\u7684\u5b89\u5168\u6027\u548c\u4f18\u79c0\u7597\u6548\uff0c\u4e5f\u611f\u53d7\u5230\u4e86\u60a3\u8005\u5bf9KRAS G12D\u9776\u5411\u7597\u6cd5\u4e0a\u5e02\u7684\u8feb\u5207\u671f\u5f85\u3002I\/II\u671f\u8bd5\u9a8c\u6210\u679c\u4e3aIII\u671f\u4e34\u5e8a\u5f00\u53d1\u5960\u5b9a\u4e86\u575a\u5b9e\u7684\u57fa\u7840\uff0c\u4e5f\u8ba9\u5168\u56fd\u7814\u7a76\u8005\u6709\u4fe1\u5fc3\u63a8\u8fdbGFH375\u6ce8\u518c\u6027\u7814\u7a76\u3002\u6211\u4eec\u671f\u5f85\u4e0e\u2018\u764c\u4e2d\u4e4b\u738b’\u7684\u535a\u5f08\u5f81\u9014\u6d8c\u73b0\u65b0\u7684\u5e0c\u671b\uff0c\u4e5f\u671f\u5f85\u5411\u4e16\u754c\u5c55\u793a\u4f18\u79c0\u7684\u4e2d\u56fd\u521b\u65b0\u7597\u6cd5\uff0c\u4ee5\u836f\u4f01\u548c\u7814\u7a76\u8005\u7684\u5171\u540c\u52aa\u529b\u9020\u798f\u60a3\u8005\u4e0e\u793e\u4f1a\u3002” \u6b64\u5916\uff0c\u4f5c\u4e3a\u52b2\u65b9\u6b27\u6d32\u591a\u4e2d\u5fc3KROCUS\u7814\u7a76\uff08\u6c1f\u6cfd\u96f7\u585e\u8054\u5408\u897f\u59a5\u6614\u5355\u6297\u7684\u4e00\u7ebf\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u6848\uff09Leading PI\uff0cRafael Rosell\u6559\u6388\u4e5f\u5728\u524d\u671f\u6c9f\u901a\u4e2d\u8868\u793a\u5f88\u9ad8\u5174\u6210\u4e3a\u52b2\u65b9\u53e6\u4e00\u9879\u521b\u65b0\u7814\u7a76\u6307\u5bfc\u59d4\u5458\u4f1a\u7684\u5916\u90e8\u4e13\u5bb6\uff0c\u5e76\u4e3a\u8fd9\u9879\u91cd\u8981\u7814\u7a76\u8d21\u732e\u529b\u91cf\uff0c\u671f\u5f85\u4e0e\u59d4\u5458\u4f1a\u7684\u4e13\u5bb6\u548c\u6210\u5458\u5408\u4f5c\u3002 \u5415\u5f3a\u535a\u58eb\u5728\u73b0\u573a\u53d1\u8a00\u4e2d\u8868\u793a\u52b2\u65b9\u7531\u6d77\u5f52\u79d1\u5b66\u5bb6\u534f\u529b\u6253\u9020\u3001\u63a2\u7d22\u539f\u521b\u578b”\u5168\u7403\u65b0”\u836f\u7269\u5f00\u53d1\uff0c\u6210\u7acb\u4e03\u5e74\u540e\u8fce\u6765\u516c\u53f8\u9996\u4e2a\u4e0a\u5e02\u4ea7\u54c1\u6c1f\u6cfd\u96f7\u585e\uff08\u56fd\u5185\u9996\u6b3e\u3001\u5168\u7403\u7b2c\u4e09\u6b3e\u83b7\u6279\u7684KRAS G12C\u6291\u5236\u5242\uff09\uff0c\u5e76\u4ee5\u6c1f\u6cfd\u96f7\u585e\u7684\u7814\u53d1\u7ecf\u9a8c\u6253\u9020\u4e86\u4e00\u4f53\u5316RAS\u7597\u6cd5\u5f00\u53d1\u4f53\u7cfb\u3002”GFH375\u5728\u56fd\u5185\u4e34\u5e8a\u83b7\u6279\u540e\u4e09\u4e2a\u5b63\u5ea6\u5185\u8fdb\u5165II\u671f\u3001\u4e00\u5e74\u534a\u4e4b\u5185\u8fdb\u5165III\u671f\uff0c\u9ad8\u6548\u4e34\u5e8a\u8fdb\u5c55\u663e\u793a\u4e86\u52b2\u65b9\u901f\u5ea6\u548c\u4ea7\u54c1\u4f18\u6548\u3002GFH375\u662f\u52b2\u65b9RAS\u7597\u6cd5\u5f00\u53d1\u7684\u65b0\u8d77\u70b9\u2014\u2014\u516c\u53f8\u540e\u7eed\u7684\u591a\u5143\u5206\u5b50\u5f62\u6001RAS\u7597\u6cd5\uff0c\u5305\u62ec\u5168\u7403\u7b2c\u4e09\u6b3e\u4e34\u5e8a\u9636\u6bb5\u5206\u5b50\u80f6\u6cdbRAS\u6291\u5236\u5242GFH276\uff08I\/II\u671f\uff09\u3001\u5168\u7403\u9996\u6b3e\u6cdbRAS\u6297\u4f53\u5076\u8054\u836f\u7269GFS784\uff08IND\u53d7\u7406\uff09\uff0c\u8be5\u7cfb\u5217\u8fd8\u6709\u671b\u5f62\u6210\u534f\u540c\u6027\u80f0\u817a\u764c\u6cbb\u7597\u77e9\u9635\u3002\u672a\u6765\u52b2\u65b9\u5c06\u4ee5\u6301\u7eed\u63d0\u5347\u7684\u56fd\u9645\u7ade\u4e89\u529b\uff0c\u5851\u9020\u5168\u7403RAS\u8d5b\u9053\u7684\u9886\u5148\u4f01\u4e1a\uff0c\u8df5\u884c\u2018\u6025\u4e34\u5e8a\u672a\u7ade\u3001\u521b\u5168\u7403\u65b0\u836f’\u7684\u4f7f\u547d\u3002” \u9e92\u9e9f\u5c55”\u7ffc”\uff0c\u53e3\u670dKRAS G12D\u6291\u5236\u5242\u65b0\u5f81\u7a0b \u80f0\u817a\u764c\u662f\u6076\u6027\u7a0b\u5ea6\u6700\u9ad8\u7684\u80bf\u7624\u4e4b\u4e00\u30015\u5e74\u751f\u5b58\u7387\u4f4e\u4e8e10%\uff0c\u76ee\u524d\u80f0\u817a\u764c\u7684\u4e00\u3001\u4e8c\u7ebf\u6807\u51c6\u6cbb\u7597\u5747\u4ee5\u5316\u7597\u4e3a\u4e3b\uff0c\u5c1a\u65e0\u8986\u76d6\u9762\u8f83\u5e7f\u7684\u76f8\u5173\u9776\u5411\u7597\u6cd5\u83b7\u6279\u4e0a\u5e02\u3002RAS\u7a81\u53d8\u5728\u80f0\u817a\u764c\u4e2d\u53d1\u751f\u7387\u9ad8\u8fbe90%\uff08KRAS G12D\u7a81\u53d8\u7387\u7ea640%\uff09\uff0cRAS\u901a\u8def\u7a81\u53d8\u53caTP53\u3001CDKN2A\u7b49\u5e38\u89c1\u5171\u7a81\u53d8\u662f\u5bfc\u81f4\u80f0\u817a\u764c\u53d1\u751f\u53d1\u5c55\u3001\u9884\u540e\u4e0d\u826f\u7684\u91cd\u8981\u56e0\u7d20\uff0cKRAS G12D\u7a81\u53d8\u66f4\u662f\u80f0\u817a\u764c\u7684\u72ec\u7acb\u9884\u540e\u4e0d\u826f\u6807\u5fd7\u3002\u65e2\u5f80\u7814\u7a76\u663e\u793a\uff0c\u76f8\u8f83\u4e8eKRAS\u91ce\u751f\u578b\u53ca\u5176\u4ed6KRAS\u7a81\u53d8\u4e9a\u578b\uff0cKRAS G12D\u7a81\u53d8\u60a3\u8005\u7684\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u53ca\u65e0\u590d\u53d1\u751f\u5b58\u671f\uff08mRFS\uff09\u5747\u660e\u663e\u7f29\u77ed\u3002 \u8fd1\u5e74\u6765\u665a\u671f\u80f0\u817a\u764c\u4e34\u5e8a\u8bd5\u9a8c\uff08\u5305\u62ec\u4e00\u7ebf\u6cbb\u7597\uff09\u9879\u76ee\u4f17\u591a\uff0cKRAS G12D\u6291\u5236\u5242\u6210\u4e3a\u5f53\u524d\u80f0\u817a\u764c\u9776\u5411\u7597\u6cd5\u5f00\u53d1\u7684\u91cd\u8981\u65b9\u5411\u3002\u4f9d\u636eESMO\u53e3\u5934\u62a5\u544a\u62ab\u9732\u7684GFH375\u5355\u836f\u7597\u6cd5\u6570\u636e\uff0c\u8be5\u4ea7\u54c1\u5355\u836f\u6cbb\u7597\u80f0\u817a\u5bfc\u7ba1\u817a\u764c\uff08PDAC\uff09\u7684\u7597\u6548\u4e3a\u5168\u7403\u540c\u7c7b\u6700\u4f73\u3002\u76ee\u524dGFH375\/VS-7375\u5df2\u8fdb\u5165\u6cbb\u7597\u4e0d\u540c\u7624\u79cd\u7684\u591a\u4e2a\u56fd\u5185\u3001\u6d77\u5916\u5355\u836f\u53ca\u8054\u5408\u7597\u6cd5\u8bd5\u9a8c\uff0c\u5176\u4e2d\u52b2\u65b9\u5df2\u5728\u56fd\u5185\u5f00\u5c55GFH375\u8054\u5408\u5316\u7597\uff08AG\uff09\u4e00\u7ebf\u6cbb\u7597PDAC\u8bd5\u9a8c\uff1b\u4e14GFH375\/VS-7375\u5df2\u83b7\u5f97FDA\u5feb\u901f\u901a\u9053\u8d44\u683c\u8ba4\u5b9a\uff0c\u6cbb\u7597\u5404\u7ebfKRAS G12D\u7a81\u53d8\u578b\u8f6c\u79fb\u6027PDAC\u3002\u6b64\u5916\uff0cGFH375\u5355\u836f\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u7597\u6548\u53ca\u603b\u4f53\u5f00\u53d1\u8fdb\u5ea6\uff0c\u4e5f\u5728\u5168\u7403KRAS G12D\u9776\u5411\u7597\u6cd5\u4e2d\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002 \u52b2\u65b9\u4e34\u5e8a\u56e2\u961f\u5728\u5927\u4f1a\u4e2d\u4ecb\u7ecd\u4e86III\u671f\u7814\u7a76\u7684\u65b9\u6848\u8bbe\u8ba1\u3001\u5165\u7ec4\u6807\u51c6\u3001\u6709\u6548\u6027\u8bc4\u4f30\u53ca\u5408\u5e76\u7528\u836f\u7b49\u5185\u5bb9\u3002\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u5468\u519b\u6559\u6388\u3001\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u674e\u82f1\u6559\u6388\u3001\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u674e\u5fd7\u4f1f\u6559\u6388\u3001\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\u5468\u9896\u73c2\u526f\u6559\u6388\u7b49\u7814\u7a76\u4e13\u5bb6\uff0c\u5728\u73b0\u573a\u6f14\u8bb2\u4e2d\u5206\u4eab\u4e86GFH375\u80f0\u817a\u764c\u6cbb\u7597\u5b9e\u8df5\u7684\u6848\u4f8b\u5206\u6790\u548c\u5b9d\u8d35\u7ecf\u9a8c\u3002\u4e0e\u4f1a\u8005\u9488\u5bf9\u6b64\u9879\u7814\u7a76\u7684\u8fdb\u5ea6\u89c4\u5212\u3001\u9879\u76ee\u7ec6\u8282\u3001\u5168\u56fd\u5404\u7814\u7a76\u4e2d\u5fc3\u7684\u6c9f\u901a\u534f\u4f5c\u7b49\u8bdd\u9898\u8fdb\u884c\u4e86\u5145\u5206\u8ba8\u8bba\uff0c\u5927\u5bb6\u671f\u5f85\u901a\u8fc7\u4ea7\u4e1a\u4e0e\u533b\u5b66\u754c\u7684\u643a\u624b\u5171\u8fdb\uff0c\u63a8\u8fdb”\u9e92\u9e9f-\u7ffc01″\u7814\u7a76\u8fdb\u5c55\u5e76\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u8fc8\u5411\u5e02\u573a\u3002 \u5173\u4e8e\u52b2\u65b9\u533b\u836f \u52b2\u65b9\u533b\u836f\uff082595.HK\uff09\u662f\u4e00\u5bb6\u5168\u7403\u5e03\u5c40\u7684\u521b\u65b0\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\uff0c\u805a\u7126\u80bf\u7624\u3001\u514d\u75ab\u7c7b\u75be\u75c5\u9886\u57df\u9ad8\u5ea6\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u4ee5\u75be\u75c5\u751f\u7269\u5b66\u673a\u7406\u548c\u4e34\u5e8a\u8f6c\u5316\u533b\u5b66\u4e3a\u6838\u5fc3\uff0c\u6784\u5efa\u5e76\u53d1\u6325\u81ea\u4e3b\u5316\u3001\u4e00\u4f53\u5316\u7814\u53d1\u4f53\u7cfb\u4f18\u52bf\uff0c\u4e3b\u653b\u5c1a\u65e0\u4e34\u5e8a\u9a8c\u8bc1\u7684\u521b\u65b0\u9776\u70b9\u4e0e\u9002\u5e94\u75c7\uff0c\u5e76\u62e5\u6709\u5168\u7403\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u3002\u81ea2017\u5e74\u6210\u7acb\u4ee5\u6765\uff0c\u52b2\u65b9\u533b\u836f\u5df2\u5efa\u7acb\u5305\u542b\u591a\u4e2a\u81ea\u4e3b\u7814\u53d1\u7684”\u5168\u7403\u65b0”\u5927\u3001\u5c0f\u5206\u5b50\u9879\u76ee\uff0c\u591a\u4e2a\u4ea7\u54c1\u5728\u4e2d\u56fd\u3001\u6b27\u6d32\u3001\u7f8e\u56fd\u8fdb\u5165\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5305\u62ec\u591a\u9879\u540e\u671f\u6216\u5173\u952e\u6027\u4e34\u5e8a\u7814\u7a76\u3002 \u8fbe\u4f2f\u7279\u00ae\uff08\u6c1f\u6cfd\u96f7\u585e\uff09\u4e3a\u52b2\u65b9\u7ba1\u7ebf\u4e2d\u9996\u4e2a\u56fd\u5185\u4e0a\u5e02\u83b7\u6279\u4ea7\u54c1\uff0c\u4e5f\u662f\u56fd\u5185\u9996\u4e2a\u3001\u5168\u7403\u7b2c\u4e09\u4e2a\u4e0a\u5e02\u7684KRAS G12C\u6291\u5236\u5242\uff1b\u76ee\u524d\u516c\u53f8\u5df2\u5f62\u6210RAS\u9776\u5411\u7597\u6cd5\u7684\u4e00\u4f53\u5316\u6df1\u8015\u77e9\u9635\uff0c\u5305\u62ec\u591a\u9776\u70b9\u3001\u591a\u79cd\u5206\u5b50\u7c7b\u578b\u7684\u9009\u62e9\u6027\u53ca\u6cdbRAS\u6291\u5236\u5242\uff0c\u591a\u4e2a\u4ea7\u54c1\u5f00\u53d1\u8fdb\u5ea6\u5728\u56fd\u5185\u5916\u540c\u9776\u70b9\u8d5b\u9053\u5904\u4e8e\u9886\u5148\uff0c\u4e14\u7814\u7a76\u6570\u636e\u591a\u6b21\u767b\u9646\u56fd\u9645\u5b66\u672f\u4f1a\u8bae\u7a81\u7834\u6027\u7814\u7a76\u6458\u8981\u53ca\u53e3\u5934\u62a5\u544a\u3002\u540c\u65f6\uff0c\u516c\u53f8\u79ef\u6781\u62d3\u5c55\u5176\u4ed6”\u5168\u7403\u65b0”\u9776\u5411\u836f\u5f00\u53d1\uff0c\u91c7\u7528\u534f\u540c\u673a\u5236\u6253\u9020\u5168\u7403\u9996\u521b\u7684\u591a\u7c7b\u578b\u53cc\u9776\u70b9\u7597\u6cd5\uff1b\u5e76\u7ed3\u5408\u4e34\u5e8a\u9700\u6c42\u4e0e\u6cbb\u7597\u7406\u5ff5\u7684\u521b\u65b0\uff0c\u4ee5\u4ea7\u54c1\u77e9\u9635\u8fdb\u519b\u80f0\u817a\u764c\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u6076\u75c5\u8d28\u7b49\u5927\u9002\u5e94\u75c7\u5e02\u573a\u3002 \u52b2\u65b9\u5df2\u83b7\u5f97\u56fd\u5bb6\u7ea7\u4e13\u7cbe\u7279\u65b0”\u5c0f\u5de8\u4eba”\u3001\u56fd\u5bb6\u7ea7\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u79f0\u53f7\uff0c\u5e76\u83b7\u5f97\u4e0a\u6d77\u5e02\u4e13\u7cbe\u7279\u65b0\u4e2d\u5c0f\u4f01\u4e1a\u3001\u4e0a\u6d77\u5e02\u8de8\u56fd\u516c\u53f8\u7814\u53d1\u4e2d\u5fc3\u3001\u4e0a\u6d77\u5e02\u4f01\u4e1a\u6280\u672f\u4e2d\u5fc3\u8ba4\u5b9a\u3002\u516c\u53f8\u8fd1\u5e74\u6765\u4e0d\u65ad\u6df1\u5316\u5546\u4e1a\u5408\u4f5c\u7f51\u7edc\uff0c\u5df2\u4e0e\u591a\u4e2a\u5883\u5185\u5916\u4e0a\u5e02\u516c\u53f8\u8fbe\u6210\u6218\u7565\u6388\u6743\u534f\u8bae\u3001\u6216\u5f00\u5c55”\u5168\u7403\u65b0”\u4e34\u5e8a\u5408\u4f5c\u5e76\u5df2\u53d6\u5f97\u79ef\u6781\u8fdb\u5c55\u3002 \u00a0 SOURCE \u52b2\u65b9\u533b\u836f","og_url":"https:\/\/moneycompass.com.my\/cn\/\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014-\u52b2\u65b9gfh375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764ciii\u671f\u7814\/","og_site_name":"Money Compass CN","article_published_time":"2026-02-12T00:15:00+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/","url":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/","name":"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(\"\u9e92\u9e9f-\u7ffc01\")\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00 - Money Compass CN","isPartOf":{"@id":"https:\/\/moneycompass.com.my\/cn\/#website"},"primaryImageOfPage":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage"},"image":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage"},"thumbnailUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg","datePublished":"2026-02-12T00:15:00+00:00","dateModified":"2026-02-12T00:15:00+00:00","author":{"@id":""},"breadcrumb":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#primaryimage","url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg","contentUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/02\/iMAGE1-Aob4sR.jpeg","width":144,"height":96},{"@type":"BreadcrumbList","@id":"https:\/\/moneycompass.com.my\/cn\/%e9%ba%92%e9%ba%9f%e5%90%af%e6%ad%a5%ef%bc%8c%e7%bf%bc%e5%b1%95%e5%be%81%e9%80%94-%e5%8a%b2%e6%96%b9gfh375%e5%8d%95%e8%8d%af%e6%b2%bb%e7%96%97%e8%83%b0%e8%85%ba%e7%99%8ciii%e6%9c%9f%e7%a0%94\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/moneycompass.com.my\/cn\/"},{"@type":"ListItem","position":2,"name":"\u9e92\u9e9f\u542f\u6b65\uff0c\u7ffc\u5c55\u5f81\u9014 | \u52b2\u65b9GFH375\u5355\u836f\u6cbb\u7597\u80f0\u817a\u764cIII\u671f\u7814\u7a76(“\u9e92\u9e9f-\u7ffc01”)\u5168\u56fd\u7814\u7a76\u8005\u4f1a\u8bae\u5706\u6ee1\u53ec\u5f00"}]},{"@type":"WebSite","@id":"https:\/\/moneycompass.com.my\/cn\/#website","url":"https:\/\/moneycompass.com.my\/cn\/","name":"Money Compass CN","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/21667"}],"collection":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/comments?post=21667"}],"version-history":[{"count":0,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/21667\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media\/21668"}],"wp:attachment":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media?parent=21667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/categories?post=21667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/tags?post=21667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}