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Lancet\uff09\u300b\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff08OS\uff09\u4e3a22.9\u4e2a\u6708\uff0c\u800c\u5316\u7597\u7ec4\u5219\u4e3a7.9\u4e2a\u6708\u3002\u4e8e2026\u5e746\u6708\uff0c\u7528\u4e8e\u4e09\u7ebf\u6cbb\u7597MET\u6269\u589e\u80c3\u764c\u7684\u4e2d\u56fd\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u6279\uff0c\u652f\u6301\u4e86\u6b64\u9879\u6279\u51c6\u7684\u2161\u671f\u4e34\u5e8a\u6570\u636e\u5df2\u4e8e\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5e74\u4f1a\u53d1\u8868\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\u4e3a32.3%\u3002FGFR\u6291\u5236\u5242\u51e1\u745e\u683c\u62c9\u66ff\u5c3c\uff08fanregratinib\uff09\u7528\u4e8e\u6cbb\u7597\u809d\u5185\u80c6\u7ba1\u764c\u7684\u5173\u952e\u6027\u2161\u671f\u7814\u7a76\u7684\u79ef\u6781\u6570\u636e\u4e8e\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u80c3\u80a0\u9053\u80bf\u7624\u5927\u4f1a\u516c\u5e03\u3002\u4e8e2026\u5e743\u6708\uff0cBTK\u6291\u5236\u5242HMPL-760\u8054\u5408\u5229\u59a5\u6614\u5355\u6297\uff08rituximab\uff09\u548c\u5316\u7597\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\u542f\u52a8\u3002<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u5c06\u4e8e\u4eca\u59292026\u5e747\u670830\u65e5\uff08\u661f\u671f\u56db\uff09\u7f8e\u56fd\u4e1c\u90e8\u590f\u4ee4\u65f6\u95f4\u4e0a\u53488\u65f6\/ \u82f1\u56fd\u590f\u4ee4\u65f6\u95f4\u4e0b\u53481\u65f6\/ \u4e2d\u56fd\u9999\u6e2f\u65f6\u95f4\u665a\u4e0a8\u65f6\u4e3e\u884c\u4e1a\u7ee9\u4f1a\u7f51\u7edc\u76f4\u64ad\uff08\u82f1\u8bed\u573a\u6b21\uff09\uff0c\u5e76\u4e8e\u660e\u59292026\u5e747\u670831\u65e5\uff08\u661f\u671f\u4e94\uff09\u4e2d\u56fd\u9999\u6e2f\u65f6\u95f4\u4e0a\u53488\u65f630\u5206\u4e3e\u884c\u4e2d\u6587\uff08\u666e\u901a\u8bdd\uff09\u573a\u6b21\u3002\u6295\u8d44\u8005\u53ef\u4e8e<a href=\"https:\/\/www.hutch-med.com\/sc\/shareholder-information\/event-information\/\" target=\"_blank\" rel=\"noopener\">www.hutch-med.com\/event<\/a>\u767b\u8bb0\u540e\u53c2\u4e0e\u5b9e\u65f6\u7f51\u7edc\u76f4\u64ad\u3002<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u975e\u6267\u884c\u4e3b\u5e2d\u827e\u4e50\u5fb7\u535a\u58eb\uff08Dr Dan Eldar\uff09\u8868\u793a\uff1a&#8221;\u548c\u9ec4\u533b\u836f\u62e5\u6709\u6e05\u6670\u7684\u6218\u7565\u7126\u70b9\uff1a\u4ee5\u5dee\u5f02\u5316\u521b\u65b0\u4e3a\u6838\u5fc3\uff0c\u6253\u9020\u5177\u6709\u5168\u7403\u7ade\u4e89\u529b\u7684\u80bf\u7624\u4ea7\u54c1\u7ec4\u5408\u3002\u8fd9\u4e00\u672a\u6765\u84dd\u56fe\u5efa\u7acb\u4e8e\u6211\u4eec\u5168\u7403\u9996\u521b\u7684\u6297\u4f53\u9776\u5411\u5076\u8054\u836f\u7269\uff08ATTC\uff09\u521b\u65b0\u6709\u6548\u8f7d\u8377\u5e73\u53f0\uff0c\u4ee5\u53ca\u5176\u4ed6\u65b0\u5174\u7684\u5927\u5206\u5b50\u521b\u65b0\u7597\u6cd5\u3002\u8fd9\u4e9b\u6280\u672f\u4e3a\u6211\u4eec\u5e26\u6765\u4e86\u591a\u5143\u5316\u7684\u673a\u9047\uff0c\u4ee5\u5f00\u53d1\u5168\u7403\u9996\u521b\uff08First-in-class\uff09\u6216\u540c\u7c7b\u6700\u4f73\uff08Best-in-class\uff09\u7684\u4ea7\u54c1\uff0c\u5e76\u4e14\u5177\u5907\u4e0e\u6807\u51c6\u7597\u6cd5\u6216\u66f4\u65b0\u7684\u836f\u7269\u8054\u5408\u7528\u836f\u7684\u6f5c\u529b\uff0c\u4ece\u800c\u5177\u5907\u6210\u4e3a\u4e00\u7ebf\u6cbb\u7597\u7684\u6f5c\u529b\u3002\u968f\u7740\u8fd9\u4e9b\u9879\u76ee\u7684\u63a8\u8fdb\uff0c\u8de8\u56fd\u5408\u4f5c\uff08\u5305\u62ec\u4e00\u4e9b\u6b63\u5728\u6d3d\u8c08\u4e2d\u7684\u9879\u76ee\uff09\u5c06\u63d0\u4f9b\u91cd\u8981\u7684\u884c\u4e1a\u80cc\u4e66\u4e0e\u8ba4\u53ef\uff0c\u62d3\u5bbd\u7814\u53d1\u8986\u76d6\u8303\u56f4\uff0c\u5e76\u52a0\u901f\u8fdb\u5165\u56fd\u9645\u4e3b\u6d41\u5e02\u573a\u3002\u6211\u4eec\u5c06\u7ee7\u7eed\u6295\u5165\u5efa\u8bbe\u6211\u4eec\u56fd\u9645\u4e00\u6d41\u7684\u7814\u53d1\u4f53\u7cfb\uff0c\u4f9d\u6258\u6700\u524d\u6cbf\u7684\u79d1\u5b66\u6280\u672f\uff0c\u5c06\u8d44\u6e90\u90e8\u7f72\u4e8e\u548c\u9ec4\u533b\u836f\u80fd\u4e3a\u5168\u7403\u60a3\u8005\u7684\u751f\u6d3b\u5e26\u6765\u91cd\u5927\u5f71\u54cd\u7684\u9886\u57df\uff0c\u540c\u65f6\u521b\u9020\u5546\u4e1a\u4e0e\u80a1\u4e1c\u4ef7\u503c\u3002&#8221;<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u4ee3\u7406\u9996\u5e2d\u6267\u884c\u5b98\u517c\u9996\u5e2d\u8d22\u52a1\u5b98\u90d1\u6cfd\u950b\u5148\u751f\u8868\u793a\uff1a&#8221;\u7231\u4f18\u7279\u00ae\u548c\u82cf\u6cf0\u8fbe\u00ae\u5728\u4e0a\u534a\u5e74\u53d6\u5f97\u5f3a\u52b2\u7684\u5e02\u573a\u9500\u552e\u989d\u589e\u957f\uff0c\u53cd\u6620\u4e86\u6211\u4eec\u7684\u5546\u4e1a\u56e2\u961f\u5728\u53bb\u5e74\u4e3a\u9002\u5e94\u4e2d\u56fd\u5e02\u573a\u4e0d\u65ad\u53d8\u5316\u7684\u76d1\u7ba1\u6307\u5f15\u4ee5\u5b9e\u73b0\u53ef\u6301\u7eed\u53d1\u5c55\u6240\u91c7\u53d6\u7684\u4e00\u7cfb\u5217\u4e3e\u63aa\u7684\u6210\u6548\uff0c\u5305\u62ec\u7cbe\u7b80\u9500\u552e\u56e2\u961f\u4ee5\u53ca\u91c7\u53d6\u66f4\u5177\u9488\u5bf9\u6027\u7684\u8425\u9500\u7b56\u7565\u4ee5\u63d0\u5347\u751f\u4ea7\u529b\u3002\u6211\u4eec\u6b63\u52a0\u901fATTC\u7684\u5f00\u53d1\uff0c\u5e76\u901a\u8fc7\u62d3\u5c55\u4eba\u624d\u548c\u4eba\u5de5\u667a\u80fd\u80fd\u529b\u4ee5\u8fdb\u4e00\u6b65\u5f3a\u5316\u65e9\u671f\u836f\u7269\u53d1\u73b0\u3002\u6211\u4eec\u8fd8\u5728\u4e0e\u8de8\u56fd\u5408\u4f5c\u4f19\u4f34\u63a2\u8ba8\u5408\u4f5c\u673a\u4f1a\uff0c\u4ee5\u52a0\u901f\u6211\u4eec\u6700\u5177\u6f5c\u529b\u9879\u76ee\u7684\u5168\u7403\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002&#8221;<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u9996\u5e2d\u6267\u884c\u5b98\uff08\u76ee\u524d\u4f11\u5047\u4e2d\uff09\u517c\u9996\u5e2d\u79d1\u5b66\u5b98\u82cf\u6170\u56fd\u535a\u58eb\u8868\u793a\uff1a&#8221;\u56fd\u5bb6\u836f\u76d1\u5c40\u57282026\u5e74\u4e0a\u534a\u5e74\u53d7\u7406\u7d22\u4e50\u5339\u5c3c\u5e03\u7528\u4e8e\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u548c\u6e29\u6297\u4f53\u578b\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u53cd\u6620\u4e86\u5176\u624e\u5b9e\u7684\u4e34\u5e8a\u6570\u636e\u5305\uff0c\u4e3a\u5176\u6f5c\u5728\u7684\u76d1\u7ba1\u548c\u5546\u4e1a\u5316\u6210\u529f\u5960\u5b9a\u575a\u5b9e\u57fa\u7840\u3002\u7d22\u4e50\u5339\u5c3c\u5e03\u518d\u6b21\u5370\u8bc1\u4e86\u6211\u4eec\u4ea7\u54c1\u9776\u70b9\u9009\u62e9\u6027\u4ee5\u53ca\u5dee\u5f02\u5316\u7684\u7597\u6548\u548c\u6bd2\u6027\u7279\u5f81\u7684\u91cd\u8981\u6027\u3002\u6211\u4eec\u7684ATTC\u5019\u9009\u836f\u7269\u4ea6\u9075\u5faa\u540c\u6837\u7684\u7814\u53d1\u7406\u5ff5\uff0c\u65e8\u5728\u5c06\u6211\u4eec\u81ea\u4e3b\u7814\u53d1\u7684\u5f3a\u6548\u5c0f\u5206\u5b50\u9776\u5411\u6709\u6548\u8f7d\u8377\u7cbe\u51c6\u8f93\u9001\u81f3\u80bf\u7624\u7ec6\u80de\uff0c\u540c\u65f6\u51cf\u5c11\u5bf9\u5065\u5eb7\u7ec4\u7ec7\u7684\u635f\u4f24\u5e76\u964d\u4f4e\u6bd2\u526f\u4f5c\u7528\u3002\u4e34\u5e8a\u524d\u6570\u636e\u663e\u793a\uff0c\u4e0e\u6807\u51c6\u7597\u6cd5\u53ca\u8fd1\u671f\u4e0a\u5e02\u6216\u6b63\u5728\u7814\u53d1\u7684\u65b0\u5174\u7597\u6cd5\u76f8\u6bd4\uff0c\u5c55\u73b0\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u80bf\u7624\u7f29\u5c0f\u6548\u679c\u3002\u6765\u81ea\u4e24\u4e2aATTC\u6709\u6548\u8f7d\u8377\u5e73\u53f0\u7684\u4e09\u4e2a\u9ad8\u5ea6\u521b\u65b0\u7684\u5206\u5b50\u6b63\u5728\u6216\u5373\u5c06\u542f\u52a8\u9996\u6b21\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u540e\u7eed\u8fd8\u5c06\u6709\u66f4\u591a\u7684\u5019\u9009\u836f\u7269\u76f8\u7ee7\u63a8\u8fdb\uff0c\u6211\u4eec\u6b63\u5728\u6253\u9020\u4ee5\u79d1\u5b66\u9a71\u52a8\u7684\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u65e8\u5728\u5c06\u5dee\u5f02\u5316\u7684\u751f\u7269\u5b66\u673a\u5236\u8f6c\u5316\u4e3a\u5207\u5b9e\u7684\u4e34\u5e8a\u83b7\u76ca\u3002&#8221;<\/p>\n<p>2026\u5e74\u4e2d\u671f\u4e1a\u7ee9\u53ca\u6700\u65b0\u4e1a\u52a1\u8fdb\u5c55<\/p>\n<p>I.\u5546\u4e1a\u8425\u8fd0<\/p>\n<p>\u4e2d\u56fd\u5e02\u573a\u9500\u552e\u989d\u5f3a\u52b2\u590d\u82cf\uff0c2026\u5e74\u4e0a\u534a\u5e74\u8fbe9,440\u4e07\u7f8e\u5143\uff0c\u8f832025\u5e74\u4e0a\u534a\u5e74\u589e\u957f32%\uff087,160\u4e07\u7f8e\u5143\uff09\uff0c\u5f97\u76ca\u4e8e\u9500\u552e\u56e2\u961f\u7684\u751f\u4ea7\u529b\u6301\u7eed\u63d0\u5347\u3002\u8fd9\u4f7f\u5f972026\u5e74\u4e0a\u534a\u5e74\u80bf\u7624\u4ea7\u54c1\u5e02\u573a\u9500\u552e\u603b\u989d\u8fbe\u52302.798\u4ebf\u7f8e\u5143\uff082025\u5e74\u4e0a\u534a\u5e74\uff1a2.344\u4ebf\u7f8e\u5143\uff09\u3002<\/p>\n<p>\u7231\u4f18\u7279\u00ae\u7684\u5e02\u573a\u9500\u552e\u989d\u589e\u957f41%\u81f36,080\u4e07\u7f8e\u5143\uff0c\u6210\u529f\u5c06\u8054\u5408\u4fe1\u8fea\u5229\u5355\u6297\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597pMMR\u5b50\u5bab\u5185\u819c\u764c\u9002\u5e94\u75c7\u7eb3\u5165\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8986\u76d6\u8303\u56f4\u3002\u540c\u65f6\u4ea6\u6210\u529f\u7eed\u7ea6\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u8fc7\u5316\u7597\u4ee5\u53ca\u65e2\u5f80\u63a5\u53d7\u8fc7\u6216\u4e0d\u9002\u5408\u63a5\u53d7\u6297VEGF\u6216\u6297EGFR\uff08RAS\u91ce\u751f\u578b\uff09\u7684\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u3002<\/p>\n<p>\u82cf\u6cf0\u8fbe\u00ae\u5e02\u573a\u9500\u552e\u989d\u589e\u957f45%\u81f31,840\u4e07\u7f8e\u5143\uff0c\u5f97\u76ca\u4e8e\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u6307\u5357\u66f4\u65b0\uff0c\u5c06\u82cf\u6cf0\u8fbe\u00ae\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u5185\u5206\u6ccc\u7624\u7684\u63a8\u8350\u7b49\u7ea7\u63d0\u5347\u81f3\u6700\u9ad8\u7684I\u7ea7\u63a8\u8350\uff0c\u5148\u4e8e\u7ade\u54c1\u751f\u957f\u6291\u7d20\u7c7b\u4f3c\u7269\u3002\u540c\u65f6\u4ea6\u5f97\u76ca\u4e8e\u8425\u9500\u7b56\u7565\u8f6c\u5411\u805a\u7126\u91cd\u70b9\u533b\u9662\u3002<\/p>\n<p>FRUZAQLA\u00ae\u5e02\u573a\u9500\u552e\u989d\u589e\u957f\u4e3b\u8981\u7531\u7f8e\u56fd\u4ee5\u5916\u5730\u533a\u7684\u9500\u552e\u63a8\u52a8\uff0c\u5176\u5e02\u573a\u589e\u957f\u7387\u7ea6\u4e3a70%\uff0c\u5f97\u76ca\u4e8e\u8fc4\u4eca\u572841\u4e2a\u56fd\u5bb6\u83b7\u6279\u6216\u4e0a\u5e02\uff0c\u5305\u62ec\u4e8e2026\u5e74\u7b2c\u4e00\u5b63\u5ea6\u5728\u6cd5\u56fd\u83b7\u7eb3\u5165\u533b\u4fdd\uff0c\u4ee5\u53ca\u4e8e2025\u5e74\u5e95\u5728\u8461\u8404\u7259\u3001\u6bd4\u5229\u65f6\u3001\u97e9\u56fd\u548c\u58a8\u897f\u54e5\u4e0a\u5e02\u3002\u8fd9\u63a8\u52a8\u4e86\u5168\u7403\u5e02\u573a\u9500\u552e\u989d\u589e\u957f\u81f31.854\u4ebf\u7f8e\u5143\u3002<\/p>\n<p>\u80bf\u7624\u4ea7\u54c1\u7684\u7efc\u5408\u6536\u5165\u603b\u989d\u8f832025\u5e74\u4e0a\u534a\u5e74\u589e\u957f23%\u81f31.214\u4ebf\u7f8e\u5143\uff0c\u4e3b\u8981\u5f97\u76ca\u4e8e\u7231\u4f18\u7279\u00ae\u53ca\u82cf\u6cf0\u8fbe\u00ae\u5e02\u573a\u9500\u552e\u989d\u7684\u5f3a\u52b2\u589e\u957f\u3002<\/p>\n<p>\u5176\u4ed6\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\u6536\u5165\uff08\u5305\u62ec\u9996\u4ed8\u6b3e\u3001\u76d1\u7ba1\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3001\u7814\u53d1\u670d\u52a1\u53ca\u8bb8\u53ef\u6536\u5165\uff09\u4e3a4,090\u4e07\u7f8e\u5143\uff0c\u5176\u4e2d\u5305\u62ec\u4e8c\u7ebf\u6cbb\u7597\u80be\u7ec6\u80de\u764c\u9002\u5e94\u75c7\u83b7\u6279\u89e6\u53d1\u7684\u6765\u81ea\u793c\u6765\u76841,810\u4e07\u7f8e\u5143\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u5176\u4ed6\u4e1a\u52a1\u6536\u5165\uff08\u4e3b\u8981\u6765\u81ea\u5904\u65b9\u836f\u5206\u9500\uff09\u4e3a1.160\u4ebf\u7f8e\u5143\uff0c\u4ece\u800c\u5b9e\u73b0\u7efc\u5408\u6536\u5165\u603b\u989d\u4e3a2.783\u4ebf\u7f8e\u5143\u3002<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u767e\u4e07\u7f8e\u5143\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5e02\u573a\u9500\u552e\u989d*<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7efc\u5408\u6536\u5165**<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74<br \/>\u4e0a\u534a\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2025\u5e74<br \/>\u4e0a\u534a\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">%\u53d8\u5316<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(\u56fa\u5b9a\u6c47\u7387)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74<br \/>\u4e0a\u534a\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2025\u5e74<br \/>\u4e0a\u534a\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">%\u53d8\u5316<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(\u56fa\u5b9a\u6c47\u7387)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">FRUZAQLA\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$185.4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$162.8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+14\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+14\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$43.1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$43.1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7231\u4f18\u7279\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$60.8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$43.0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+41\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+33\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$47.1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$33.6<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+40\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+32\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u82cf\u6cf0\u8fbe\u00ae <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$18.4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$12.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+45\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+37\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$18.4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$12.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+45\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+37\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6c83\u745e\u6c99\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$15.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$15.2<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+3\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(-3\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$13.3<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$9.0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+48\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+39\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8fbe\u552f\u73c2\u00ae(TAZVERIK\u00ae)***<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$(0.5)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$0.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$(0.5)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$0.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80bf\u7624\u4ea7\u54c1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$279.8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$234.4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+19\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+17\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$121.4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$99.1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+23\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+18\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b66\u7530\u9996\u4ed8\u6b3e\u3001\u76d1\u7ba1\u91cc\u7a0b\u7891\u53ca\u7814\u53d1\u670d\u52a1\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$20.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$29.5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-30\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(-30\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u6536\u5165 (\u7814\u53d1\u670d\u52a1\u53ca\u8bb8\u53ef)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$20.2<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$14.9<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+35\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+35\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\u5408\u8ba1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$162.3<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$143.5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">+13\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(+10\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u4e1a\u52a1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$116.0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$134.2<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-14\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(-19\u00a0%)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6536\u5165\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$278.3<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$277.7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(-4\u00a0%)<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">* \u5c31FRUZAQLA\u00ae\u3001\u7231\u4f18\u7279\u00ae\u548c\u6c83\u745e\u6c99\u00ae\uff0c\u4e3b\u8981\u5206\u522b\u4ee3\u8868\u6b66\u7530\u3001\u793c\u6765\u548c\u963f\u65af\u5229\u5eb7\u63d0\u4f9b\u7684\u5bf9\u7b2c\u4e09\u65b9\u7684\u603b\u9500\u552e\u989d\u3002<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">** \u5c31FRUZAQLA\u00ae\uff0c\u4ee3\u8868\u6b66\u7530\u652f\u4ed8\u7ed9\u548c\u9ec4\u533b\u836f\u7684\u751f\u4ea7\u6536\u5165\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\uff1b\u5c31\u7231\u4f18\u7279\u00ae\uff0c\u4ee3\u8868\u793c\u6765\u5411\u548c\u9ec4\u533b\u836f\u652f\u4ed8\u7684\u751f\u4ea7\u6536\u5165\u3001\u63a8\u5e7f\u53ca\u8425\u9500\u670d\u52a1\u6536<br \/>\u5165\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\uff0c\u4ee5\u53ca\u7531\u548c\u9ec4\u533b\u836f\u5f00\u5177\u53d1\u7968\u7684\u5bf9\u5176\u4ed6\u7b2c\u4e09\u65b9\u7684\u9500\u552e\u989d\uff1b\u5c31\u6c83\u745e\u6c99\u00ae\uff0c\u4ee3\u8868\u963f\u65af\u5229\u5eb7\u5411\u548c\u9ec4\u533b\u836f\u652f\u4ed8\u7684\u751f\u4ea7\u6536\u5165\u548c\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\uff0c\u4ee5<br \/>\u53ca\u7531\u548c\u9ec4\u533b\u836f\u5f00\u5177\u53d1\u7968\u7684\u5bf9\u5176\u4ed6\u7b2c\u4e09\u65b9\u7684\u9500\u552e\u989d\uff1b\u5c31\u82cf\u6cf0\u8fbe\u00ae \u53ca\u8fbe\u552f\u73c2\u00ae\uff0c\u4ee3\u8868\u548c\u9ec4\u533b\u836f\u5bf9\u7b2c\u4e09\u65b9\u7684\u4ea7\u54c1\u9500\u552e\u989d\u3002<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">*** Ipsen\u4e3a\u8fbe\u552f\u73c2\u00ae\u7684\u4e0a\u5e02\u8bb8\u53ef\u6301\u6709\u4eba\uff0c\u548c\u9ec4\u533b\u836f\u4f5c\u4e3a\u5176\u56fd\u5185\u4ee3\u7406\/\u88ab\u8bb8\u53ef\u65b9\u30022026\u5e743\u6708\uff0cIpsen\u57fa\u4e8e\u8fdb\u884c\u4e2d\u7684 SYMPHONY-1\u7814\u7a76\u51fa\u73b0\u7684\u5b89\u5168<br \/>\u6027\u6570\u636e\uff0c\u81ea\u613f\u4ece\u6240\u6709Ipsen\u5e02\u573a\u64a4\u56de\u8fbe\u552f\u73c2\u00ae\uff0c\u5373\u65f6\u751f\u6548\u3002<\/span><\/p>\n<\/div>\n<p>II. 2026\u5e74\u6ce8\u518c\u5ba1\u6279\u8fdb\u5c55<\/p>\n<p>\u4e8e2026\u5e746\u6708\uff0c\u8d5b\u6c83\u66ff\u5c3c\uff08savolitinib\uff09\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u7528\u4e8e\u4e09\u7ebf\u6cbb\u7597MET\u6269\u589e\u80c3\u764c\u3002\u4e8e2026\u5e742\u6708\uff0c\u8d5b\u6c83\u66ff\u5c3c\u7684\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\u83b7\u745e\u58eb\u533b\u836f\u7ba1\u7406\u5c40\uff08Swissmedic\uff09\u6279\u51c6\uff08\u4e34\u65f6\u6388\u6743\uff09\uff0c\u8054\u5408\u6cf0\u745e\u6c99\u00ae\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u4f34\u6709MET\u6269\u589e\u548c\/\u6216\u8fc7\u8868\u8fbe\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002\u4e8e2026\u5e745\u6708\uff0c\u544b\u55b9\u66ff\u5c3c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\uff0c\u8054\u5408\u4fe1\u8fea\u5229\u5355\u6297\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u80be\u7ec6\u80de\u764c\u3002\u4e8e2026\u5e744\u6708\uff0c\u7d22\u4e50\u5339\u5c3c\u5e03\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\uff0c\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u6e29\u6297\u4f53\u578b\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840\u3002\u4e8e2026\u5e742\u6708\uff0c\u7d22\u4e50\u5339\u5c3c\u5e03\u91cd\u65b0\u63d0\u4ea4\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\uff0c\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u3002\u4e8e2026\u5e743\u6708\uff0c\u76ca\u666e\u751f\uff08Ipsen\uff09\u5728\u4e2d\u56fd\u4e3b\u52a8\u64a4\u56de\u4ed6\u6cfd\u53f8\u4ed6\uff08tazemetostat\uff09\u3002<\/p>\n<p>III. 2026\u5e74\u540e\u671f\u4e34\u5e8a\u9879\u76ee\u8fdb\u5c55<\/p>\n<p>\u8d5b\u6c83\u66ff\u5c3c\uff08\u4e2d\u56fd\u5546\u54c1\u540d\uff1a\u6c83\u745e\u6c99\u00ae\uff09\uff0c\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u53e3\u670d\u7684MET\u6291\u5236\u5242<\/p>\n<p>\u7ee7\u4e8e2025\u5e74\u4e0b\u534a\u5e74\u5b8c\u6210\u60a3\u8005\u62db\u52df\u540e\uff0cSAFFRON\u548cSANOVO\u7814\u7a76\u7684\u9876\u7ebf\u7ed3\u679c\u9884\u8ba1\u4e8e2026\u4e0b\u534a\u5e74\u516c\u5e03\uff1aSAFFRON\u5168\u7403\u2162\u671f\u7814\u7a76\u6709\u671b\u652f\u6301\u4e8e\u5168\u7403\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u7528\u4e8e\u4e8c\u7ebf\/\u4e09\u7ebf\u6cbb\u7597\u4f34\u6709MET\u6269\u589e\u548c\/\u6216\u8fc7\u8868\u8fbe\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\uff08NCT05261399\uff09\u3002SANOVO\u4e2d\u56fd\u2162\u671f\u7814\u7a76\u6709\u671b\u652f\u6301\u4e8e\u4e2d\u56fd\u63d0\u4ea4\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4f34\u6709MET\u8fc7\u8868\u8fbe\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\uff08NCT05009836\uff09\u3002SACHI\u4e2d\u56fd\u2162\u671f\u7814\u7a76\u7684\u4e9a\u7ec4\u5206\u6790\u7ed3\u679c\u4e8e2026\u5e741\u6708\u53d1\u8868\u4e8e\u300a\u67f3\u53f6\u5200\u300b\uff0c\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u4f34\u6709MET\u6269\u589e\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\uff0c\u5728\u6392\u9664\u540e\u7eed\u63a5\u53d7MET\u6291\u5236\u5242\u6cbb\u7597\u7684\u5bf9\u7167\u7ec4\u60a3\u8005\u540e\uff0c\u4e2d\u4f4dOS\u4e3a22.9\u4e2a\u6708\uff0c\u800c\u5316\u7597\u7ec4\u5219\u4e3a7.9\u4e2a\u6708\uff08HR 0.32\uff09\u3002\u7528\u4e8e\u4e09\u7ebf\u6cbb\u7597MET\u6269\u589e\u80c3\u764c\u7684\u4e2d\u56fd\u2161\u671f\u5173\u952e\u6027\u7814\u7a76\u7684\u79ef\u6781\u6570\u636e\u4e8e2026\u5e746\u6708\u5728ASCO\u5e74\u4f1a\u4e0a\u516c\u5e03\uff0c\u5e76\u4e8e\u300a\u81ea\u7136\u2022\u533b\u5b66\uff08Nature Medicine\uff09\u300b\u53d1\u8868\uff0c\u7ecf\u72ec\u7acb\u5ba1\u67e5\u59d4\u5458\u4f1a\u8bc4\u4f30\u7684ORR\u4e3a32.3%\uff0c\u4e2d\u4f4dPFS\u4e3a4.0\u4e2a\u6708\uff0c\u800c\u4e2d\u4f4dOS\u5219\u4e3a6.9\u4e2a\u6708\uff08NCT04923932\uff09\u3002<\/p>\n<p>\u7d22\u4e50\u5339\u5c3c\u5e03\uff08HMPL-523\uff09\uff0c\u4e00\u79cd\u7814\u7a76\u6027\u7684\u9ad8\u9009\u62e9\u6027\u53e3\u670dSyk\u6291\u5236\u5242 <\/p>\n<p>\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u6e29\u6297\u4f53\u578b\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840\u7684ESLIM-02\u4e2d\u56fd\u2162\u671f\u7814\u7a76\u7684\u79ef\u6781\u6570\u636e\u4e8e2026\u5e746\u6708\u5728EHA\u5e74\u4f1a\u4e0a\u516c\u5e03\uff0c\u7814\u7a76\u5df2\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\u6301\u7eed\u5e94\u7b54\u738766.0%\uff0c\u51fa\u73b0\u5e94\u7b54\u7684\u4e2d\u4f4d\u65f6\u95f4\u4e3a3.1\u5468\uff0c\u800c\u4e2d\u4f4d\u7d2f\u8ba1\u5e94\u7b54\u6301\u7eed\u65f6\u95f4\u4e3a16.1\u5468\u3002<\/p>\n<p>\u51e1\u745e\u683c\u62c9\u66ff\u5c3c\uff08fanregratinib\uff0cHMPL-453\uff09\uff0c\u4e00\u79cd\u65b0\u578b\u3001\u9ad8\u9009\u62e9\u6027\u53ca\u5f3a\u6548\u7684FGFR 1\u30012 \u548c3\u6291\u5236\u5242<\/p>\n<p>\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597FGFR2\u878d\u5408\/\u91cd\u6392\u809d\u5185\u80c6\u7ba1\u764c\u7684\u4e2d\u56fd\u2161\u671f\u5173\u952e\u6027\u7814\u7a76\u7684\u79ef\u6781\u6570\u636e\u4e8e2026\u5e747\u6708\u5728ESMO\u80c3\u80a0\u9053\u80bf\u7624\u5927\u4f1a\u4e0a\u516c\u5e03\uff0c\u7814\u7a76\u5df2\u8fbe\u5230\u72ec\u7acb\u5ba1\u67e5\u59d4\u5458\u4f1a\u8bc4\u4f30\u7684ORR 42.5%\u7684\u4e3b\u8981\u7ec8\u70b9\uff0c\u4e2d\u4f4dPFS\u4e3a6.9\u4e2a\u6708\uff0c\u4e2d\u4f4dOS\u4e3a16.6\u4e2a\u6708\u3002\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u809d\u5185\u80c6\u7ba1\u764c\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u4e8e2025\u5e7412\u6708\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\uff0c\u5e76\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\uff08NCT04353375\uff09\u3002<\/p>\n<p>HMPL-760\uff0c\u4e00\u79cd\u975e\u5171\u4ef7\u7684\u7b2c\u4e09\u4ee3BTK\uff08\u5305\u62ec\u91ce\u751f\u578b\u548cC481S\u7a81\u53d8\u578bBTK\uff09\u6291\u5236\u5242 <\/p>\n<p>\u4e8e2026\u5e743\u6708\u542f\u52a8\u4e2d\u56fd\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8054\u5408R-GemOx\u65b9\u6848\uff08\u5229\u59a5\u6614\u5355\u6297\/rituximab\u3001\u5409\u897f\u4ed6\u6ee8\/gemcitabine\u548c\u5965\u6c99\u5229\u94c2\/oxaliplatin\uff09\u5bf9\u6bd4\u5b89\u6170\u5242\u8054\u5408R-GemOx\u65b9\u6848\u7528\u4e8e\u4e8c\u7ebf\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6027\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u60a3\u8005\uff08NCT07409428\uff09\u3002\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\u4e3a\u7814\u7a76\u8005\u8bc4\u4f30\u7684PFS\u548cOS\u3002<\/p>\n<p>IV.\u6297\u4f53\u5076\u8054\u836f\u7269\u7814\u53d1<\/p>\n<p>HMPL-A251\uff0c\u4e00\u79cd\u5168\u7403\u9996\u521b\u7684PI3K\/PIKK-HER2 ATTC\uff0c\u7531\u9ad8\u9009\u62e9\u6027\u3001\u5f3a\u6548\u7684PI3K\/PIKK\u6291\u5236\u5242\u4f5c\u4e3a\u6709\u6548\u8f7d\u8377\u548c\u4eba\u6e90\u5316\u6297HER2 IgG1\u6297\u4f53\u901a\u8fc7\u53ef\u88c2\u89e3\u7684\u8fde\u63a5\u5b50\uff08linker\uff09\u5076\u8054\u800c\u6210<\/p>\n<p>\u4e00\u9879\u5242\u91cf\u9012\u589e\u548c\u5242\u91cf\u6269\u5c55\u7814\u7a76\u6b63\u5728\u8fdb\u884c\u4e2d\uff0c\u7528\u4e8e\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u3001\u4f34\u6709HER2\u8868\u8fbe\u7684\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\uff0c\u9996\u4f4d\u60a3\u8005\u5df2\u4e8e2025\u5e7412\u6708\u7ed9\u836f\uff08NCT07228247\uff09\u3002\u4e34\u5e8a\u524d\u6570\u636e\u663e\u793a\uff0c\u8be5\u836f\u7269\u5728DXd\u6297\u836f\u7ec6\u80de\u7cfb\u4e2d\u5c55\u73b0\u51fa\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u4e14\u901a\u8fc7\u5dee\u5f02\u5316\u7684\u4f5c\u7528\u673a\u5236\uff0c\u5728\u4e0e\u5316\u7597\u8054\u5408\u7528\u836f\u65f6\u5c55\u73b0\u51fa\u826f\u597d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u3002<\/p>\n<p>HMPL-A580\uff0c\u4e00\u79cd\u5168\u7403\u9996\u521b\u7684PI3K\/PIKK-EGFR ATTC\uff0c\u7531\u9ad8\u9009\u62e9\u6027\u3001\u5f3a\u6548\u7684PI3K\/PIKK\u6291\u5236\u5242\u4f5c\u4e3a\u6709\u6548\u8f7d\u8377\u548c\u6297EGFR IgG1\u6297\u4f53\u901a\u8fc7\u53ef\u88c2\u89e3\u7684\u8fde\u63a5\u5b50\u5076\u8054\u800c\u6210<\/p>\n<p>\u4e00\u9879\u5242\u91cf\u9012\u589e\u548c\u6269\u5c55\u7814\u7a76\u6b63\u5728\u8fdb\u884c\u4e2d\uff0c\u7528\u4e8e\u6cbb\u7597\u5b9e\u4f53\u7624\uff08\u5305\u62ec\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u5934\u9888\u90e8\u9cde\u72b6\u7ec6\u80de\u764c\u53ca\u98df\u7ba1\u9cde\u72b6\u7ec6\u80de\u764c\uff09\uff0c\u9996\u4f4d\u60a3\u8005\u5df2\u4e8e2026\u5e743\u6708\u7ed9\u836f\uff08NCT07396584\uff09\u3002\u4e8e2026\u5e74AACR\u5e74\u4f1a\u4e0a\u516c\u5e03\u7684\u4e34\u5e8a\u524d\u6570\u636e\u663e\u793a\uff0c\u5728\u5965\u5e0c\u66ff\u5c3c\u8010\u836f\u7684EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7ec6\u80de\u7cfb\u4e2d\u89c2\u5bdf\u5230\u80bf\u7624\u7f29\u5c0f\uff0c\u4e14\u8054\u5408\u5965\u5e0c\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597EGFR\u7a81\u53d8\u3001PAM\u672a\u6539\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7ec6\u80de\u7cfb\u65f6\uff0c\u5c55\u73b0\u51fa\u826f\u597d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u3002<\/p>\n<p>HMPL-A830\u7684\u4e2d\u56fd\/\u7f8e\u56fd\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u5df2\u53d6\u5f97\u6279\u51c6<\/p>\n<p>\u8ba1\u5212\u4e8e2026\u5e74\u4e0b\u534a\u5e74\u542f\u52a8\u5168\u7403\u4e34\u5e8a\u8bd5\u9a8c\u3002\u4e34\u5e8a\u524d\u6570\u636e\u663e\u793a\uff0c\u4e0e\u9488\u5bf9\u76f8\u540c\u9776\u70b9\u7684\u6297\u4f53\u6216\u5c0f\u5206\u5b50\u76f8\u6bd4\uff0c\u5c55\u73b0\u51fa\u66f4\u4f18\u7684\u836f\u6548\u548c\u5b89\u5168\u6027\u7279\u5f81\uff0c\u76f8\u5173\u6570\u636e\u5c06\u4e8e\u5b66\u672f\u4f1a\u8bae\u4e0a\u516c\u5e03\u3002<\/p>\n<p>V. 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\u2013 \u672c\u516c\u544a\u4e2d\u63d0\u53ca\u4e0d\u5305\u62ec\u878d\u8d44\u6d3b\u52a8\u7684\u8c03\u6574\u540e\u96c6\u56e2\u51c0\u73b0\u91d1\u6d41\u53ca\u6309\u7167\u56fa\u5b9a\u6c47\u7387\u8ba1\u7b97\u62a5\u544a\u7684\u8d22\u52a1\u6307\u6807\u5747\u57fa\u4e8e\u975eGAAP\u8d22\u52a1\u6307\u6807\u3002\u8bf7\u53c2\u9605&#8221;\u975eGAAP\u8d22\u52a1\u6307\u6807\u7684\u4f7f\u7528\u548c\u5bf9\u8d26&#8221;\uff0c\u4ee5\u5206\u522b\u4e86\u89e3\u8fd9\u4e9b\u8d22\u52a1\u6307\u6807\u7684\u89e3\u91ca\uff0c\u4ee5\u53ca\u8fd9\u4e9b\u8d22\u52a1\u6307\u6807\u4e0e\u6700\u5177\u53ef\u6bd4\u6027\u7684GAAP\u6307\u6807\u5bf9\u8d26\u7684\u8fdb\u4e00\u6b65\u8d44\u6599\u3002<\/p>\n<p>\u8d22\u52a1\u6307\u5f15<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u91cd\u75332026\u5e74\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\u7efc\u5408\u6536\u5165\u7684\u5168\u5e74\u6307\u5f15\u57283.3\u4ebf\u7f8e\u5143\u81f34.5\u4ebf\u7f8e\u5143\u4e4b\u95f4\u3002\u548c\u9ec4\u533b\u836f\u5c06\u5145\u5206\u5229\u7528\u5176\u5f3a\u5927\u7684\u73b0\u91d1\u8d44\u6e90\uff0c\u52a0\u901fATTC\u9879\u76ee\u7684\u5168\u7403\u5f00\u53d1\u5e76\u63a2\u7d22\u6295\u8d44\u673a\u4f1a\u3002\u80a1\u4e1c\u53ca\u6295\u8d44\u8005\u5e94\u6ce8\u610f\uff1a<\/p>\n<p>\u672c\u516c\u53f8\u4e0d\u4fdd\u8bc1\u8d22\u52a1\u6307\u5f15\u4e2d\u5305\u542b\u7684\u9648\u8ff0\u5c06\u5b9e\u73b0\uff0c\u6216\u5176\u4e2d\u5305\u542b\u7684\u8d22\u52a1\u4e1a\u7ee9\u5c06\u5b9e\u73b0\u6216\u53ef\u80fd\u5b9e\u73b0\uff1b\u53ca<\/p>\n<p>\u672c\u516c\u53f8\u8fc7\u53bb\u66fe\u4fee\u8ba2\u6211\u4eec\u7684\u8d22\u52a1\u6307\u5f15\uff0c\u56e0\u6b64\u5e94\u53c2\u8003\u6211\u4eec\u5728\u672c\u516c\u544a\u520a\u53d1\u65e5\u671f\u540e\u5c31\u4efb\u4f55\u8d22\u52a1\u6307\u5f15\u66f4\u65b0\u7684\u516c\u544a\u3002<\/p>\n<p>\u8d22\u52a1\u6982\u8981<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7b80\u660e\u7efc\u5408\u8d44\u4ea7\u8d1f\u503a\u8868\u6570\u636e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u5343\u7f8e\u5143\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e8e2026\u5e746\u670830\u65e5<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e8e2025\u5e7412\u670831\u65e5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d44\u4ea7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(\u672a\u7ecf\u5ba1\u6838)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269\u548c\u77ed\u671f\u6295\u8d44<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,374,817<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,367,275<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5e94\u6536\u8d26\u6b3e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">117,556<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">126,750<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u6d41\u52a8\u8d44\u4ea7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">61,036<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">73,317<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7269\u4e1a\u3001\u5382\u623f\u53ca\u8bbe\u5907<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">93,788<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">94,623<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5bf9\u80a1\u6743\u88ab\u6295\u8d44\u4f01\u4e1a\u7684\u6295\u8d44<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">11,020<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">10,865<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u975e\u6d41\u52a8\u8d44\u4ea7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">78,210<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">80,267<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d44\u4ea7\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,736,427<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,753,097<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d1f\u503a\u53ca\u80a1\u4e1c\u6743\u76ca<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5e94\u4ed8\u8d26\u6b3e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">33,646<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">45,533<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u5e94\u4ed8\u6b3e\u53ca\u5e94\u8ba1\u5f00\u652f<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">197,627<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">208,892<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u94f6\u884c\u8d37\u6b3e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">94,508<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">93,160<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9012\u5ef6\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">27,630<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">51,547<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u8d1f\u503a<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">108,048<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">102,703<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d1f\u503a\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">461,459<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">501,835<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u672c\u516c\u53f8\u80a1\u4e1c\u6743\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,260,776<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,237,926<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u975e\u63a7\u80a1\u6743\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">14,192<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">13,336<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d1f\u503a\u53ca\u80a1\u4e1c\u6743\u76ca\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,736,427<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,753,097<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7b80\u660e\u7efc\u5408\u7ecf\u8425\u8868\u6570\u636e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u672a\u7ecf\u5ba1\u6838\uff0c\u5343\u7f8e\u5143\uff0c\u80a1\u4efd\u548c\u6bcf\u80a1\u6570\u636e\u9664\u5916\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f36\u670830\u65e5\u6b62\u516d\u4e2a\u6708<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2025\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6536\u5165\uff1a<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\uff0d\u4e0a\u5e02\u4ea7\u54c1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">121,434<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">99,039<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\uff0d\u7814\u53d1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">40,887<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">44,408<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\u7efc\u5408\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">162,321<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">143,447<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u4e1a\u52a1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">115,966<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">134,230<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6536\u5165\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">278,287<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">277,677<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ecf\u8425\u5f00\u652f\uff1a<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6536\u5165\u6210\u672c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(152,158)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(167,577)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7814\u53d1\u5f00\u652f<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(78,783)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(71,990)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9500\u552e\u53ca\u884c\u653f\u5f00\u652f<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(46,477)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(41,624)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ecf\u8425\u5f00\u652f\u603b\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(277,418)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(281,191)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u51fa\u552e\u4e00\u5bb6\u80a1\u6743\u88ab\u6295\u8d44\u4f01\u4e1a\u7684\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">477,456<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5176\u4ed6\u6536\u76ca\u51c0\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">12,784<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">21,650<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9664\u6240\u5f97\u7a0e\u5f00\u652f\u53ca\u6240\u5360\u80a1\u6743\u88ab\u6295\u8d44\u4f01\u4e1a\u6743\u76ca\u6536\u76ca\u524d\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">13,653<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">495,592<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u5f97\u7a0e\u5f00\u652f<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(1,209)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(2,029)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u5f97\u7a0e\u5f00\u652f\uff0d\u51fa\u552e\u4e00\u5bb6\u80a1\u6743\u88ab\u6295\u8d44\u4f01\u4e1a<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2014<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(61,133)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u5360\u80a1\u6743\u88ab\u6295\u8d44\u4f01\u4e1a\u6743\u76ca\u9664\u7a0e\u540e\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">3,798<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">23,125<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u51c0\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">16,242<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">455,555<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u51cf\uff1a\u975e\u63a7\u80a1\u6743\u76ca\u5e94\u5360\u51c0\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(314)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(601)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c\u9ec4\u533b\u836f\u5e94\u5360\u51c0\u6536\u76ca<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">15,928<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">454,954<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c\u9ec4\u533b\u836f\u5e94\u5360\u6bcf\u80a1\u666e\u901a\u80a1\u76c8\u5229 (\u6bcf\u80a1\u666e\u901a\u80a1\uff0c\u7f8e\u5143)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u57fa\u672c <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.02<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.53<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u644a\u8584<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.02<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.52<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8ba1\u7b97\u6bcf\u80a1\u666e\u901a\u80a1\u76c8\u5229\u6240\u7528\u80a1\u6570<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u57fa\u672c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">865,770,498<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">857,038,725<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u644a\u8584<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">872,869,494<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">872,564,513<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c\u9ec4\u533b\u836f\u5e94\u5360\u6bcf\u4efdADS \u76c8\u5229 (\u6bcf\u4efdADS\uff0c\u7f8e\u5143)<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u57fa\u672c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.09<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2.65<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u644a\u8584<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">0.09<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2.61<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8ba1\u7b97\u6bcf\u4efd ADS \u76c8\u5229\u6240\u7528\u7684ADS\u4efd\u6570<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u57fa\u672c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">173,154,100<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">171,407,745<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2013 \u644a\u8584<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">174,573,899<\/span><\/p>\n<p><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">174,512,903<\/span><\/p>\n<\/div>\n<p>\u5173\u4e8e\u548c\u9ec4\u533b\u836f<\/p>\n<p>\u548c\u9ec4\u533b\u836f\uff08\u7eb3\u65af\u8fbe\u514b\/\u4f26\u6566\u8bc1\u4ea4\u6240\uff1aHCM\uff1b\u9999\u6e2f\u4ea4\u6613\u6240\uff1a13\uff09\u662f\u4e00\u5bb6\u5904\u4e8e\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u53d1\u73b0\u3001\u5168\u7403\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6cbb\u7597\u764c\u75c7\u548c\u514d\u75ab\u6027\u75be\u75c5\u7684\u9776\u5411\u836f\u7269\u548c\u514d\u75ab\u7597\u6cd5\u3002\u81ea\u6210\u7acb\u4ee5\u6765\uff0c\u548c\u9ec4\u533b\u836f\u81f4\u529b\u4e8e\u5c06 \u81ea\u4e3b\u53d1\u73b0\u7684\u5019\u9009\u836f\u7269\u5e26\u5411\u5168\u7403\u60a3\u8005\uff0c\u9996\u4e09\u4e2a\u836f\u7269\u73b0\u5df2\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u5176\u4e2d\u9996\u4e2a\u836f\u7269\u4ea6\u4e8e\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u65e5\u672c\u7b49\u5168\u7403 \u5404\u5730\u83b7\u6279\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u8be6\u60c5\uff0c\u8bf7\u8bbf\u95ee\uff1a<a href=\"https:\/\/www.hutch-med.com\/sc\/\" target=\"_blank\" rel=\"noopener\">www.hutch-med.com<\/a>\u6216\u5173\u6ce8\u6211\u4eec\u7684<a href=\"https:\/\/www.linkedin.com\/company\/hutchmed\/\" target=\"_blank\" rel=\"noopener\">\u9886\u82f1<\/a>\u4e13\u9875\u3002<\/p>\n<p>\u7b80\u79f0\u4f7f\u7528<\/p>\n<p>\u9664\u6587\u610f\u53e6\u6709\u6240\u6307\u5916\uff0c\u5426\u5219\u672c\u516c\u544a\u4e2d\u6240\u79f0&#8221;\u96c6\u56e2&#8221;\u3001&#8221;\u516c\u53f8&#8221;\u3001&#8221;\u548c\u9ec4\u533b\u836f&#8221;\u3001&#8221;\u548c\u9ec4\u533b\u836f\u96c6\u56e2&#8221;\u3001&#8221;\u6211\u4eec&#8221;\u548c&#8221;\u6211\u4eec\u7684&#8221;\u6307\u548c\u9ec4\u533b\u836f\uff08\u4e2d\u56fd\uff09\u6709\u9650\u516c\u53f8\u53ca\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u9664\u975e\u6587\u4e2d\u53e6\u6709\u8bf4\u660e\u6216\u6307\u660e\u3002<\/p>\n<p>\u8fc7\u5f80\u4e1a\u7ee9\u548c\u524d\u77bb\u6027\u9648\u8ff0<\/p>\n<p>\u672c\u516c\u544a\u6240\u8f7d\u672c\u96c6\u56e2\u4e4b\u8868\u73b0\u548c\u7ecf\u8425\u4e1a\u7ee9\u5c5e\u5386\u53f2\u6027\u8d28\uff0c\u4e14\u8fc7\u5f80\u8868\u73b0\u5e76\u4e0d\u4fdd\u8bc1\u672c\u96c6\u56e2\u4e4b\u672a\u6765\u4e1a\u7ee9\u3002\u672c\u516c\u544a\u5305\u542b\u7b26\u54081995\u5e74\u300a\u7f8e\u56fd\u79c1\u4eba\u8bc1\u5238\u8bc9\u8bbc\u6539\u9769\u6cd5\u6848\u300b&#8221;\u5b89\u5168\u6e2f&#8221;\u6761\u6b3e\u4e2d\u5b9a\u4e49\u7684\u524d\u77bb\u6027\u9648\u8ff0\u3002\u8be5\u7b49\u524d\u77bb\u6027\u9648\u8ff0\u53ef\u4ee5\u7528\u8bf8\u5982&#8221;\u5c06\u4f1a&#8221;\u3001&#8221;\u671f\u671b&#8221;\u3001&#8221;\u9884\u671f&#8221;\u3001&#8221;\u672a\u6765&#8221;\u3001&#8221;\u6253\u7b97&#8221;\u3001&#8221;\u8ba1\u5212&#8221;\u3001&#8221;\u76f8\u4fe1&#8221;\u3001&#8221;\u4f30\u8ba1&#8221;\u3001&#8221;\u7ba1\u7ebf&#8221;\u3001&#8221;\u53ef\u80fd&#8221;\u3001&#8221;\u6f5c\u5728&#8221;\u3001&#8221;\u5168\u7403\u9996\u521b&#8221;\u3001&#8221;\u540c\u7c7b\u6700\u4f73&#8221;\u3001&#8221;\u65e8\u5728&#8221;\u3001&#8221;\u76ee\u6807&#8221;\u3001&#8221;\u6307\u5bfc&#8221;\u3001&#8221;\u8ffd\u6c42&#8221;\u6216\u7c7b\u4f3c\u672f\u8bed\uff0c\u6216\u901a\u8fc7\u5bf9\u6f5c\u5728\u5019\u9009\u836f\u7269\u3001\u6f5c\u5728\u5019\u9009\u836f\u7269\u9002\u5e94\u75c7\u7684\u660e\u793a\u6216\u6697\u793a\u8ba8\u8bba\uff0c\u6216\u901a\u8fc7\u8ba8\u8bba\u6218\u7565\u3001\u8ba1\u5212\u3001\u9884\u671f\u6216\u610f\u56fe\u6765\u8bc6\u522b\u3002\u9601\u4e0b\u8bf7\u52ff\u8fc7\u5206\u501a\u8d56\u8fd9\u4e9b\u524d\u77bb\u6027\u9648\u8ff0\u3002\u8be5\u7b49\u524d\u77bb\u6027\u9648\u8ff0\u53cd\u6620\u4e86\u7ba1\u7406\u5c42\u6839\u636e\u76ee\u524d\u7684\u4fe1\u5ff5\u548c\u671f\u671b\u800c\u5bf9\u672a\u6765\u4e8b\u4ef6\u7684\u9884\u671f\uff0c\u5e76\u53d7\u5230\u5df2\u77e5\u53ca\u672a\u77e5\u98ce\u9669\u4e0e\u4e0d\u786e\u5b9a\u6027\u7684\u5f71\u54cd\u3002\u5982\u82e5\u8be5\u7b49\u98ce\u9669\u6216\u4e0d\u786e\u5b9a\u6027\u4e2d\u7684\u4e00\u9879\u6216\u591a\u9879\u51fa\u73b0\uff0c\u6216\u8005\u57fa\u672c\u5047\u8bbe\u88ab\u8bc1\u660e\u5c5e\u4e0d\u6b63\u786e\uff0c\u5219\u5b9e\u9645\u7ed3\u679c\u53ef\u80fd\u4e0e\u524d\u77bb\u6027\u9648\u8ff0\u4e2d\u6240\u8f7d\u4e4b\u7ed3\u679c\u6709\u91cd\u5927\u51fa\u5165\u3002\u548c\u9ec4\u533b\u836f\u4e0d\u80fd\u4fdd\u8bc1\u5176\u4efb\u4f55\u5019\u9009\u836f\u7269\u5747\u5c06\u4f1a\u5728\u4efb\u4f55\u5e02\u573a\u4e0a\u83b7\u51c6\u9500\u552e\uff0c\u4ea6\u4e0d\u80fd\u4fdd\u8bc1\u5df2\u83b7\u5f97\u7684\u4efb\u4f55\u6279\u51c6\u5728\u672a\u6765\u7ee7\u7eed\u6709\u6548\uff0c\u6216\u8005\u7531\u548c\u9ec4\u533b\u836f\u53ca\/\u6216\u5176\u5408\u4f5c\u4f19\u4f34\u9500\u552e\u6216\u4ee5\u5176\u4ed6\u65b9\u5f0f\u5c06\u4ea7\u54c1\u5546\u4e1a\u5316\uff08\u7edf\u79f0&#8221;\u548c\u9ec4\u533b\u836f\u4ea7\u54c1&#8221;\uff09\u5c06\u8fbe\u5230\u4efb\u4f55\u7279\u5b9a\u7684\u6536\u5165\u6216\u51c0\u6536\u76ca\u6c34\u5e73\u3002\u5c24\u5176\uff0c\u7ba1\u7406\u5c42\u7684\u9884\u671f\u53ef\u80fd\u4f1a\u53d7\u5230\u4ee5\u4e0b\u56e0\u7d20\u7684\u5f71\u54cd\uff1a\u610f\u6599\u4e4b\u5916\u7684\u76d1\u7ba1\u884c\u52a8\u6216\u5ef6\u8fdf\u6216\u4e00\u822c\u6027\u7684\u653f\u5e9c\u76d1\u7ba1\uff1b\u7814\u7a76\u4e0e\u5f00\u53d1\u4e2d\u56fa\u6709\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u5305\u62ec\u65e0\u6cd5\u6ee1\u8db3\u5173\u952e\u7684\u5173\u4e8e\u53d7\u8bd5\u8005\u7684\u5165\u7ec4\u7387\u3001\u65f6\u673a\u548c\u53ef\u7528\u6027\u7684\u7814\u7a76\u5047\u8bbe\uff0c\u5176\u8981\u7b26\u5408\u7814\u7a76\u7684\u7eb3\u5165\u53ca\u6392\u9664\u6807\u51c6\u4ee5\u53ca\u8d44\u91d1\u8981\u6c42\uff0c\u4e34\u5e8a\u65b9\u6848\u7684\u53d8\u66f4\u3001\u610f\u5916\u4e0d\u5229\u4e8b\u4ef6\u6216\u5b89\u5168\u6027\u3001\u8d28\u91cf\u6216\u751f\u4ea7\u65b9\u9762\u7684\u95ee\u9898\uff1b\u5019\u9009\u836f\u7269\u5ef6\u8fdf\u6216\u65e0\u6cd5\u6ee1\u8db3\u784f\u7a76\u7684\u4e3b\u8981\u6216\u6b21\u8981\u7ec8\u70b9\uff1b\u5019\u9009\u836f\u7269\u5ef6\u8fdf\u6216\u65e0\u6cd5\u83b7\u5f97\u4e0d\u540c\u53f8\u6cd5\u7ba1\u8f96\u533a\u7684\u76d1\u7ba1\u6279\u51c6\u6216\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u83b7\u5f97\u76d1\u7ba1\u6279\u51c6\u540e\u7684\u4f7f\u7528\u60c5\u51b5\uff0c\u5e02\u573a\u8ba4\u53d7\u6027\u53ca\u5546\u4e1a\u6210\u529f\uff1b\u6240\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\/\u6216\u5546\u4e1a\u5316\u7ade\u4e89\u4ea7\u54c1\u548c\u5019\u9009\u836f\u7269\u53ef\u80fd\u6bd4\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u53ca\u5019\u9009\u836f\u7269\u66f4\u6709\u4f18\u52bf\u6216\u66f4\u5177\u6210\u672c\u6548\u76ca\uff1b\u653f\u5e9c\u5f53\u5c40\u548c\u5176\u4ed6\u7b2c\u4e09\u65b9\u7684\u7814\u7a76\uff08\u65e0\u8bba\u7531\u548c\u9ec4\u533b\u836f\u6216\u5176\u4ed6\u4eba\u58eb\u8fdb\u884c\u53ca\u65e0\u8bba\u5c5e\u5f3a\u5236\u6216\u81ea\u613f\uff09\u6216\u5efa\u8bae\u53ca\u6307\u5f15\u5bf9\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u53ca\u5f00\u53d1\u4e2d\u7684\u5019\u9009\u836f\u7269\u7684\u5546\u4e1a\u6210\u529f\u7684\u5f71\u54cd\uff1b\u548c\u9ec4\u533b\u836f\u5236\u9020\u53ca\u7ba1\u7406\u591a\u79cd\u4ea7\u54c1\u53ca\u5019\u9009\u836f\u7269\u4f9b\u5e94\u94fe\u7684\u80fd\u529b\uff08\u5305\u62ec\u5404\u79cd\u7b2c\u4e09\u65b9\u670d\u52a1\uff09\uff1b\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u80fd\u5426\u4ece\u7b2c\u4e09\u65b9\u652f\u4ed8\u673a\u6784\u83b7\u5f97\u62a5\u9500\u53ca\u83b7\u62a5\u9500\u7684\u7a0b\u5ea6\uff0c\u5305\u62ec\u79c1\u4eba\u652f\u4ed8\u673a\u6784\u7684\u533b\u7597\u5065\u5eb7\u53ca\u4fdd\u9669\u8ba1\u5212\u4ee5\u53ca\u653f\u5e9c\u4fdd\u9669\u8ba1\u5212\uff1b\u5f00\u53d1\u3001\u751f\u4ea7\u53ca\u9500\u552e\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u7684\u6210\u672c\uff1b\u5728\u9700\u8981\u65f6\u83b7\u5f97\u989d\u5916\u8d44\u91d1\u7684\u80fd\u529b\uff1b\u4e3a\u548c\u9ec4\u533b\u836f\u4ea7\u54c1\u548c\u5019\u9009\u836f\u7269\u83b7\u5f97\u5e76\u7ef4\u6301\u77e5\u8bc6\u4ea7\u6743\u4fdd\u62a4\u80fd\u529b\uff1b\u548c\u9ec4\u533b\u836f\u5b9e\u73b0\u5176\u4efb\u4f55\u8d22\u52a1\u9884\u6d4b\u6216\u6307\u5f15\u7684\u80fd\u529b\u4ee5\u53ca\u8be5\u7b49\u9884\u6d4b\u6216\u6307\u5f15\u6240\u4f9d\u636e\u7684\u5047\u8bbe\u7684\u53d8\u5316\uff1b\u904f\u5236\u533b\u7597\u6210\u672c\u7684\u5168\u7403\u8d8b\u52bf\uff0c\u5305\u62ec\u6301\u7eed\u7684\u4ef7\u683c\u538b\u529b\uff1b\u5b9e\u9645\u548c\u6f5c\u5728\u6cd5\u5f8b\u7a0b\u5e8f\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u5176\u4e2d\u5305\u62ec\u5b9e\u9645\u6216\u6f5c\u5728\u4ea7\u54c1\u8d23\u4efb\u8bc9\u8bbc\u3001\u6709\u5173\u9500\u552e\u548c\u884c\u9500\u884c\u4e3a\u7684\u8bc9\u8bbc\u548c\u8c03\u67e5\u3001\u77e5\u8bc6\u4ea7\u6743\u7ea0\u7eb7\u4ee5\u53ca\u4e00\u822c\u6027\u7684\u653f\u5e9c\u8c03\u67e5\uff1b\u4ee5\u53ca\u6574\u4f53\u7ecf\u6d4e\u548c\u884c\u4e1a\u72b6\u51b5\uff0c\u5305\u62ec\u8bb8\u591a\u56fd\u5bb6\u6301\u7eed\u75b2\u5f31\u7684\u7ecf\u6d4e\u548c\u91d1\u878d\u73af\u5883\u5f71\u54cd\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u672a\u6765\u5168\u7403\u6c47\u7387\u7684\u4e0d\u786e\u5b9a\u6027\uff0c\u5168\u7403\u5229\u7387\u3001\u5730\u7f18\u653f\u6cbb\u5173\u7cfb\u3001\u5236\u88c1\u548c\u5173\u7a0e\u7684\u4e0d\u786e\u5b9a\u6027\u3002\u6709\u5173\u524d\u8ff0\u5404\u9879\u548c\u5176\u4ed6\u98ce\u9669\u7684\u8fdb\u4e00\u6b65\u8ba8\u8bba\uff0c\u8bf7\u53c2\u9605\u548c\u9ec4\u533b\u836f\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u3001\u4f26\u6566\u8bc1\u5238\u4ea4\u6613\u6240\u548c\u9999\u6e2f\u4ea4\u6613\u6240\u63d0\u4ea4\u7684\u6587\u4ef6\u3002\u548c\u9ec4\u533b\u836f\u5728\u672c\u516c\u544a\u4e2d\u63d0\u4f9b\u4e4b\u8d44\u6599\u622a\u81f3\u672c\u516c\u544a\u65e5\u671f\uff0c\u5e76\u4e14\u4e0d\u627f\u62c5\u56e0\u65b0\u7684\u8d44\u6599\u3001\u672a\u6765\u4e8b\u4ef6\u6216\u5176\u4ed6\u539f\u56e0\u800c\u66f4\u65b0\u4efb\u4f55\u524d\u77bb\u6027\u9648\u8ff0\u7684\u4e49\u52a1\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u672c\u516c\u544a\u5305\u542b\u548c\u9ec4\u533b\u836f\u4ece\u884c\u4e1a\u51fa\u7248\u7269\u548c\u7b2c\u4e09\u65b9\u5e02\u573a\u7814\u7a76\u516c\u53f8\u4f5c\u51fa\u7684\u62a5\u544a\u4e2d\u83b7\u5f97\u7684\u7edf\u8ba1\u6570\u636e\u548c\u4f30\u8ba1\u3002\u5c3d\u7ba1\u548c\u9ec4\u533b\u836f\u8ba4\u4e3a\u8be5\u7b49\u51fa\u7248\u7269\u3001\u62a5\u544a\u548c\u8c03\u67e5\u7814\u7a76\u662f\u53ef\u9760\u7684\uff0c\u4f46\u662f\u548c\u9ec4\u533b\u836f\u5c1a\u672a\u72ec\u7acb\u9a8c\u8bc1\u8be5\u7b49\u6570\u636e\uff0c\u4e0d\u80fd\u4fdd\u8bc1\u8be5\u7b49\u6570\u636e\u7684\u51c6\u786e\u6027\u6216\u5b8c\u6574\u6027\u3002\u8bf7\u9601\u4e0b\u6ce8\u610f\u4e0d\u8981\u8fc7\u5ea6\u8003\u8651\u8be5\u7b49\u6570\u636e\u3002\u8be5\u7b49\u6570\u636e\u6d89\u53ca\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\uff0c\u5e76\u53ef\u80fd\u6839\u636e\u5404\u79cd\u56e0\u7d20\uff08\u5305\u62ec\u524d\u8ff0\u56e0\u7d20\uff09\u6709\u6240\u66f4\u6539\u3002<\/p>\n<p>\u5185\u5e55\u6d88\u606f<\/p>\n<p>\u672c\u516c\u544a\u5305\u542b\uff08\u6b27\u76df\uff09\u7b2c596\/2014\u53f7\u6761\u4f8b\uff08\u8be5\u6761\u4f8b\u6784\u6210\u300a2018\u5e74\u6b27\u6d32\u8054\u76df\uff08\u9000\u51fa\uff09\u6cd5\u300b\u5b9a\u4e49\u7684\u6b27\u76df\u4fdd\u7559\u6cd5\u5f8b\u7684\u4e00\u90e8\u5206\uff09\u7b2c7\u6761\u89c4\u5b9a\u7684\u5185\u5e55\u6d88\u606f\u3002<\/p>\n<p>\u533b\u7597\u4fe1\u606f<\/p>\n<p>\u672c\u516c\u544a\u6240\u63d0\u5230\u7684\u4ea7\u54c1\u53ef\u80fd\u5e76\u672a\u5728\u6240\u6709\u56fd\u5bb6\u4e0a\u5e02\uff0c\u6216\u53ef\u80fd\u4ee5\u4e0d\u540c\u7684\u5546\u6807\u8fdb\u884c\u9500\u552e\uff0c\u6216\u7528\u4e8e\u4e0d\u540c\u7684\u75c5\u75c7\uff0c\u6216\u91c7\u7528\u4e0d\u540c\u7684\u5242\u91cf\uff0c\u6216\u62e5\u6709\u4e0d\u540c\u7684\u6548\u529b\u3002\u672c\u6587\u4e2d\u6240\u5305\u542b\u7684\u4efb\u4f55\u4fe1\u606f\u90fd\u4e0d\u5e94\u88ab\u89c6\u4e3a\u662f\u4efb\u4f55\u5904\u65b9\u836f\u7684\u63a8\u9500\u3001\u63a8\u5e7f\u6216\u5e7f\u544a\uff0c\u5305\u62ec\u90a3\u4e9b\u6b63\u5728\u7814\u53d1\u7684\u836f\u7269\u3002<\/p>\n<p>\u8bcd\u6c47\u8868<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">1L<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e00\u7ebf (First-line)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2L<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e8c\u7ebf (Second-line)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">3L<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e09\u7ebf (Third-line)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">AACR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a (American Association for Cancer Research)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ADC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6297\u4f53\u836f\u7269\u5076\u8054\u7269 (Antibody-drug conjugate)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ADS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u9884\u6258\u8bc1\u5238 (American depositary shares)\uff0c\u6bcf\u4e00\u4efd\u4ee3\u8868\u4e94\u80a1\u666e\u901a\u80a1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">AIHA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840 (Autoimmune hemolytic anemia)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">AKT<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u86cb\u767d\u6fc0\u9176B (Protein kinase B)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">AML<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5 (Acute myeloid leukemia)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASCO<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a (American Society of Clinical Oncology)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASH<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a (American Society of Hematology)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u963f\u65af\u5229\u5eb7 <br \/>(AstraZeneca)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">AstraZeneca AB\uff0cAstraZeneca plc \u7684\u9644\u5c5e\u516c\u53f8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ATTC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6297\u4f53\u9776\u5411\u5076\u8054\u836f\u7269 (Antibody-targeted therapy conjugates)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">BICR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u76f2\u6001\u72ec\u7acb\u4e2d\u5fc3\u8bc4\u4f30 (Blinded independent central review)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">BID<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6bcf\u65e5\u4e24\u6b21 (Twice a day)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u56fd\u94f6\u884c (BOC)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u56fd\u94f6\u884c\u80a1\u4efd\u6709\u9650\u516c\u53f8 (Bank of China Limited)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">BTK<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5e03\u9c81\u987f\u916a\u6c28\u9178\u6fc0\u9176 (Bruton&#8217;s tyrosine kinase)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CDMO<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5408\u540c\u7814\u53d1\u751f\u4ea7\u673a\u6784 (Contract Development and Manufacturing Organization)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u56fa\u5b9a\u6c47\u7387 (CER)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Constant exchange rate\u3002\u6211\u4eec\u4ea6\u62a5\u544a\u6309\u56fa\u5b9a\u6c47\u7387 (CER)\uff0c\u4e00\u79cd\u975eGAAP\u6307\u6807\uff0c\u8ba1\u7b97<br \/>\u4e1a\u7ee9\u53d8\u5316\u3002\u8bf7\u53c2\u9605\u300c\u975eGAAP \u8d22\u52a1\u6307\u6807\u7684\u4f7f\u7528\u548c\u5bf9\u8d26\u300d\uff0c\u4ee5\u5206\u522b\u4e86\u89e3\u8fd9\u4e9b\u8d22\u52a1\u6307\u6807<br \/>\u7684\u89e3\u91ca\uff0c\u4ee5\u53ca\u8fd9\u4e9b\u8d22\u52a1\u6307\u6807\u4e0e\u6700\u5177\u53ef\u6bd4\u6027\u7684GAAP \u6307\u6807\u7684\u5bf9\u8d26\u3002<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CI<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f6e\u4fe1\u533a\u95f4 (Confidence interval)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CLL<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5 (Chronic lymphocytic leukemia)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CMC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5316\u5b66\u3001\u751f\u4ea7\u548c\u8d28\u91cf\u63a7\u5236 (Chemistry, Manufacturing, and Controls)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CR+CRh<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7efc\u5408\u5b8c\u5168\u7f13\u89e3\u6216\u5b8c\u5168\u7f13\u89e3\u4f34\u90e8\u5206\u8840\u6db2\u5b66\u7f13\u89e3 (Combined complete remission +<br \/>complete remission with partial hematologic recovery)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CRC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ed3\u76f4\u80a0\u764c (Colorectal cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">CSF-1R<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u96c6\u843d\u523a\u6fc0\u56e0\u5b50-1\u53d7\u4f53 (Colony-stimulating factor 1 receptor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">DCR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u75be\u75c5\u63a7\u5236\u7387 (Disease control rate)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">DLBCL<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624 (Diffuse large B-cell lymphoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">DoR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f13\u89e3\u6301\u7eed\u65f6\u95f4 (Duration of response)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">DRR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6301\u7eed\u5e94\u7b54\u7387 (Durable response rate)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EASI<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6e7f\u75b9\u9762\u79ef\u548c\u4e25\u91cd\u7a0b\u5ea6\u6307\u6570 (Eczema area and severity index)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EGFR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53 (Epidermal growth factor receptor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EGFR\u7a81\u53d8 (EGFRm)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u7a81\u53d8 (Epidermal growth factor receptor mutated)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EHA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a (European Hematology Association)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ELCC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b27\u6d32\u80ba\u764c\u5927\u4f1a (The European Lung Cancer Congress)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u793c\u6765 (Eli Lilly)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Lilly (Shanghai) Management Company Limited<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EMC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5b50\u5bab\u5185\u819c\u764c (Endometrial cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">EORTC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b27\u6d32\u764c\u75c7\u7814\u7a76\u548c\u6cbb\u7597\u7ec4\u7ec7 (European Organization for Research and Treatment of <br \/>Cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Epizyme<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Epizyme, Inc.\uff0cIpsen\u65d7\u4e0b\u516c\u53f8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">epNET<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u975e\u80f0\u817a\u795e\u7ecf\u5185\u5206\u6ccc\u7624 (Extra-pancreatic neuroendocrine tumor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ESCC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u98df\u9053\u9cde\u72b6\u7ec6\u80de\u764c (Esophageal Squamous Cell Carcinoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ESG<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u73af\u5883\u3001\u793e\u4f1a\u53ca\u7ba1\u6cbb (Environmental, Social and Governance)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ESMO<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b27\u6d32\u80bf\u7624\u5b66\u4f1a (European Society for Medical Oncology)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">FDA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (Food and Drug Administration)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">FGFR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6210\u7ea4\u7ef4\u7ec6\u80de\u751f\u957f\u56e0\u5b50\u53d7\u4f53 (Fibroblast growth factor receptor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">FLT3<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">FMS\u6837\u916a\u6c28\u9178\u6fc0\u91763 (FMS-like tyrosine kinase 3)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9996\u4f8b\u60a3\u8005\u5165\u7ec4 (FPI)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">First patient in<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">GAAP<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e00\u822c\u516c\u8ba4\u4f1a\u8ba1\u539f\u5219 (Generally Accepted Accounting Principles)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">GC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80c3\u764c (Gastric cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">GMP<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u836f\u54c1\u751f\u4ea7\u8d28\u91cf\u7ba1\u7406\u89c4\u8303 (Good Manufacturing Practice)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">HER2<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4eba\u7c7b\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532 (Human Epidermal growth factor Receptor 2)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9999\u6e2f\u4ea4\u6613\u6240 (HKEX)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9999\u6e2f\u8054\u5408\u4ea4\u6613\u6240\u6709\u9650\u516c\u53f8\u4e3b\u677f (The Main Board of The Stock Exchange of Hong Kong Limited)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">HNSCC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5934\u9888\u90e8\u9cde\u72b6\u7ec6\u80de\u764c (Head and Neck Squamous Cell Carcinoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">HR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u98ce\u9669\u6bd4 (Hazard Ratio)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">IDH1\/2<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176-1\u6216\u5f02\u67e0\u6aac\u9178\u8131\u6c22\u9176-2 (Isocitrate dehydrogenase-1 OR isocitrate <br \/>dehydrogenase-2)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ICC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u809d\u5185\u80c6\u7ba1\u764c (Intrahepatic cholangiocarcinoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">IIT<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7814\u7a76\u8005\u53d1\u8d77\u7684\u4e34\u5e8a\u8bd5\u9a8c (Investigator-initiated trial)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ImageneBio<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ImageneBio, Inc<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">IND<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7 (Investigational new drug application)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5e02\u573a\u9500\u552e\u989d (in-<br \/>market sales)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7531\u793c\u6765 (\u7231\u4f18\u7279\u00ae)\u3001\u6b66\u7530 (FRUZAQLA\u00ae)\u3001\u963f\u65af\u5229\u5eb7(\u6c83\u745e\u6c99\u00ae) \u53ca\u548c\u9ec4\u533b\u836f (\u7231\u4f18\u7279<br \/>\u00ae\u3001\u82cf\u6cf0\u8fbe\u00ae\u3001\u6c83\u745e\u6c99\u00ae\u53ca\u8fbe\u552f\u73c2\u00ae) \u6240\u63d0\u4f9b\u5411\u7b2c\u4e09\u65b9\u7684\u603b\u9500\u552e\u989d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Ipsen<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Ipsen SA\uff0cEpizyme, Inc.\u7684\u6bcd\u516c\u53f8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">IRC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u72ec\u7acb\u5ba1\u67e5\u59d4\u5458\u4f1a (Independent review committee)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ITP<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7 (Immune thrombocytopenia purpura)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">JAMA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u300a\u7f8e\u56fd\u533b\u5b66\u4f1a\u6742\u5fd7\u300b(Journal of the American Medical Association)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">LPR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8d37\u6b3e\u5e02\u573a\u62a5\u4ef7\u5229\u7387 (Loan Prime Rate)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">MAA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7 (Marketing Authorisation Application)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">mCRC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c (Metastatic colorectal cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">mDoR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4 (median Duration of response)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">MET<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u914d\u4f53\u4e0a\u76ae\u95f4\u8d28\u8f6c\u5316\u56e0\u5b50 (ligand mesenchymal epithelial transition factor) \u6216\u4e3a\u6b64\u914d<br \/>\u4f53\u7f16\u7801\u7684\u57fa\u56e0MET<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">METex14<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">MET\u5916\u663e\u5b5014\u8df3\u53d8 (MET exon 14 skipping alteration)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">mOS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u4f4d\u603b\u751f\u5b58\u671f (median Overall survival)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">mPFS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f (median Progression-free survival)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">mTOR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u54fa\u4e73\u52a8\u7269\u96f7\u5e15\u9709\u7d20\u9776\u86cb\u767d (Mechanistic target of rapamycin)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NCCN<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u56fd\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc (National Comprehensive Cancer Network)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NDA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7 (New Drug Application)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NET<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u795e\u7ecf\u5185\u5206\u6ccc\u7624 (Neuroendocrine tumor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NHL<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624 (Non-Hodgkin lymphoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u56fd\u5bb6\u836f\u76d1\u5c40 (NMPA)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (China National Medical Products Administration)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55 <br \/>(NRDL)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u300a\u4e2d\u56fd\u56fd\u5bb6\u57fa\u672c\u533b\u7597\u4fdd\u9669\u3001\u5de5\u4f24\u4fdd\u9669\u548c\u751f\u80b2\u4fdd\u9669\u836f\u54c1\u76ee\u5f55\u300b(China National <br \/>Reimbursement Drug List)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NSCLC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u975e\u5c0f\u7ec6\u80de\u80ba\u764c (Non-small cell lung cancer)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ORR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5ba2\u89c2\u7f13\u89e3\u7387 (Objective response rate)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">OS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u603b\u751f\u5b58\u671f (Overall survival)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4eba\u6c11\u94f6\u884c (PBOC)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u56fd\u4eba\u6c11\u94f6\u884c (People&#8217;s Bank of China)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PD-1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u86cb\u767d-1 (Programmed cell death protein-1)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PDAC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80f0\u817a\u5bfc\u7ba1\u817a\u764c (Pancreatic ductal adenocarcinoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PFS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u65e0\u8fdb\u5c55\u751f\u5b58\u671f (Progression free survival)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PI3K<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u78f7\u9178\u808c\u9187-3-\u6fc0\u9176 (Phosphatidylinositol 3-kinase)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PI3K\u03b4<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u78f7\u9178\u808c\u9187-3-\u6fc0\u9176\u03b4 (Phosphoinositide 3-kinase-\u03b4)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">PIKK<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u78f7\u8102\u9170\u808c\u91873-\u6fc0\u9176\u76f8\u5173\u6fc0\u9176 (Phosphatidylinositol 3-kinase-related kinase)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">pMMR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9519\u914d\u4fee\u590d\u5b8c\u6574 (Proficient mismatch repair)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">pNET<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80f0\u817a\u795e\u7ecf\u5185\u5206\u6ccc\u7624 (Pancreatic neuroendocrine tumor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">R\/R<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u590d\u53d1\u53ca\/\u6216\u96be\u6cbb\u6027 (Relapsed and\/or refractory)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">RAS<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5927\u9f20\u8089\u7624 (Rat sarcoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">RCC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80be\u7ec6\u80de\u764c (Renal cell carcinoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4eba\u6c11\u5e01 (RMB)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u56fd\u6cd5\u5b9a\u8d27\u5e01<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">RP2D<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u63a8\u8350\u5242\u91cf (The recommended phase 2 dose)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9500\u552e\u53ca\u884c\u653f\u5f00\u652f<br \/>(S&amp;A)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9500\u552e\u53ca\u884c\u653f\u5f00\u652f (Selling and administrative expenses)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e0a\u6d77\u548c\u9ec4\u836f\u4e1a <br \/>(SHPL)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e0a\u6d77\u548c\u9ec4\u836f\u4e1a\u6709\u9650\u516c\u53f8 (Shanghai Hutchison Pharmaceuticals Limited)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">SLL<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624 (Small lymphocytic lymphoma)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">sNDA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7 (supplemental New Drug Application)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u751f\u957f\u6291\u7d20\u7c7b\u4f3c\u7269 <br \/>(SSA)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Somatostatin Analogs<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Syk<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u813e\u916a\u6c28\u9178\u6fc0\u9176 (Spleen tyrosine kinase)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b66\u7530 (Takeda)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Takeda Pharmaceuticals International AG, Takeda Pharmaceutical Company <br \/>Limited \u7684\u9644\u5c5e\u516c\u53f8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">TEAE<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6cbb\u7597\u671f\u95f4\u4e0d\u826f\u4e8b\u4ef6 (Treatment emergent adverse events)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">TKI<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242 (Tyrosine kinase inhibitor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">TPO<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8840\u5c0f\u677f\u751f\u6210\u7d20 (Thrombopoietin)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">TPO-RA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8840\u5c0f\u677f\u751f\u6210\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242 (Thrombopoietin receptor agonists)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">TRAE<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6 (Treatment-related adverse events)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">VEGFR<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53 (Vascular endothelial growth factor receptor)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">wAIHA<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">=<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6e29\u6297\u4f53\u578b\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840 (Warm autoimmune hemolytic anemia)<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>SOURCE \u548c\u9ec4\u533b\u836f(\u4e2d\u56fd)\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"<p>\u2014 \u5728\u7231\u4f18\u7279\u00ae\u548c\u82cf\u6cf0\u8fbe\u00ae\u5e26\u9886\u4e0b\uff0c\u4e2d\u56fd\u7684\u4ea7\u54c1\u9500\u552e\u6301\u7eed\u590d\u82cf\uff0c\u5206\u522b\u589e\u957f\u8d85\u8fc740% \u2014 \u2014 \u7f8e\u56fd\u4ee5\u5916\u5e02\u573a\u9500\u552e\u63a8\u52a8FRUZAQLA\u00ae\u589e\u957f\uff0c\u73b0\u5df2\u4e8e41\u4e2a\u56fd\u5bb6\u83b7\u6279\u6216\u4e0a\u5e02 \u2014 \u2014 \u6297\u4f53\u9776\u5411\u5076\u8054\u836f\u7269\uff08ATTC\uff09\u5e73\u53f0\u8fdb\u5c55\u5f3a\u52b2\uff0c\u4e0d\u65ad\u63a8\u51fa\u5177\u5907\u5e7f\u6cdb\u6cbb\u7597\u6f5c\u529b\u7684\u521b\u65b0\u5019\u9009\u836f\u7269 \u2014 \u9999\u6e2f\u3001\u4e0a\u6d77\u548c\u65b0\u6cfd\u897f\u5dde\u5f17\u6d1b\u52d2\u59c6\u516c\u56ed2026\u5e747\u670830\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u548c\u9ec4\u533b\u836f\uff08\u4e2d\u56fd\uff09\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0&#8221;\u548c\u9ec4\u533b\u836f&#8220;\u3001&#8221;\u672c\u516c\u53f8&#8221;\u6216&#8221;\u6211\u4eec&#8221;\uff09\u4eca\u65e5\u516c\u5e03\u622a\u81f32026\u5e746\u670830\u65e5\u6b62\u516d\u4e2a\u6708\u7684\u8d22\u52a1\u4e1a\u7ee9\u4ee5\u53ca\u63d0\u4f9b\u5173\u952e\u4e34\u5e8a\u9879\u76ee\u548c\u5546\u4e1a\u5316\u53d1\u5c55\u7684\u6700\u65b0\u8fdb\u5c55\u3002 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$185.4 $162.8 +14\u00a0% [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":26924,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-26923","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u548c\u9ec4\u533b\u836f\u516c\u5e032026\u5e74\u4e2d\u671f\u4e1a\u7ee9 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u548c\u9ec4\u533b\u836f\u516c\u5e032026\u5e74\u4e2d\u671f\u4e1a\u7ee9\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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