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class=\"prnews_span\">ASC30_48_39FDC\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74\u7b2c\u56db\u5b63\u5ea6\u9012\u4ea4IND\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u80f0\u6dc0\u7d20\u53d7\u4f53 (SARA)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC39<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74\u7b2c\u4e09\u5b63\u5ea6\u9012\u4ea4IND<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">GLP-1R\/\u80f0\u6dc0\u7d20\u53d7\u4f53 (SARA)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC30_39FDC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2026\u5e74\u7b2c\u4e09\u5b63\u5ea6\u9012\u4ea4IND<\/span><\/p>\n<\/div>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6ce8\u91ca\uff1aFDC\uff1a\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bSARA\uff1a\u9009\u62e9\u6027\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u3002<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u590d\u65b9\u5236\u5242\uff08GLP-1\/GIP\/\u80f0\u6dc0\u7d20\uff09<\/p>\n<p>\u6b4c\u793c\u7684\u540c\u7c7b\u9996\u521b\u3001\u9776\u5411GLP-1\u3001GIP\u53ca\u80f0\u6dc0\u7d20\uff08SARA\uff09\u7684\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff08ASC30_48_39FDC\uff09\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u7ed9\u836f\u4e03\u5929\u540e\uff0c\u5c55\u73b0\u51fa\u4f9d\u8d56\u4e8eGIPR\u6fc0\u52a8\u5242\uff08ASC48\uff09\u5242\u91cf\u3001\u4e14\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u7684\u4f53\u91cd\u4e0b\u964d\uff0c\u51cf\u91cd\u9ad8\u8fbe15.2%\u3002\u8fd9\u8f83\u9776\u5411GLP-1R\u548c\u80f0\u6dc0\u7d20\u53d7\u4f53\uff08SARA\uff09\u7684\u53e3\u670d\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff08ASC30_39FDC\uff09\u7684\u51cf\u91cd\u6548\u679c\u76f8\u5bf9\u63d0\u5347\u9ad8\u8fbe120%\uff08\u88682\uff09\u3002\u8be5\u6570\u636e\u8868\u660eGIP\u6210\u5206\uff08ASC48\uff09\u5bf9\u4e8eASC30_48_<span>39FDC<\/span>\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u81f3\u5173\u91cd\u8981\u3002ASC30_48_<span>39FDC<\/span>\u662f\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u7c7b\u4f3c\u4e8e\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\u6ce8\u5c04\u5242\uff08\u5982\u66ff\u5c14\u6cca\u80bd\u8054\u5408eloralintide\uff09\u3002\u5728\u8fd1\u671f\u516c\u5e03\u7684\u4e00\u9879\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u66ff\u5c14\u6cca\u80bd\u8054\u5408eloralintide\u4e8e\u7b2c32\u5468<span>\u5728\u4eba\u4f53\u4e2d<\/span>\u5b9e\u73b0\u4e8629%\u7684<span>\u4f53\u91cd<\/span>\u4e0b\u964d[1]\u3002<\/p>\n<p>\u88682. \u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u8fde\u7eed\u4e03\u5929\u6bcf\u65e5\u4e00\u6b21\u53e3\u670dASC30_48_39<span>FDC<\/span><\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ec4\u522b<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ed9\u836f\u65b9\u6848<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u76f8\u8f83\u57fa\u7ebf\u7684\u603b\u4f53\u91cd\u53d8\u5316<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC30_39FDC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(GLP-1R\/\u80f0\u6dc0\u7d20\u53d7\u4f53<br \/>(SARA))<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg ASC30<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c 0.1 mg\/kg ASC39<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-6.9\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC30_48_39FDC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(GLP-1R\/GIPR\/\u80f0\u6dc0\u7d20\u53d7<br \/>\u4f53(SARA))<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg ASC30,<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1 mg\/kg ASC48\uff0c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c0.1 mg\/kg ASC39<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-12.1%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(p &lt; 0.05 \u5bf9\u6bd4 ASC30_39FDC)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg ASC30,<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg ASC48\uff0c <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c0.1 mg\/kg ASC39<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-15.2%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(p &lt; 0.01 \u5bf9\u6bd4 ASC30_39FDC)<\/span><\/p>\n<\/div>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6ce8\u91ca\uff1aFDC\uff1a\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bSARA\uff1a\u9009\u62e9\u6027\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u3002<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u7c7b\u4f3celoralintide\u7684\u53e3\u670d\u5c0f\u5206\u5b50SARA<\/p>\n<p>\u6b4c\u793c\u7684\u540c\u7c7b\u9996\u521b\u6bcf\u65e5\u4e00\u6b21\u7c7b\u4f3celoralintide\u7684\u53e3\u670d\u5c0f\u5206\u5b50SARA\uff08ASC39\uff09\u662f\u6b4c\u793c\u53e3\u670d\u5c0f\u5206\u5b50\u80a5\u80d6\u75c7\u6cbb\u7597\u7ba1\u7ebf\u7ec4\u5408\u4e2d\u7684\u7b2c\u4e8c\u5927\u652f\u67f1\u3002\u5728\u4e34\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cASC39\u5c55\u73b0\u51fa\u4e0eeloralintide\u7c7b\u4f3c\u7684\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u4e0e\u7597\u6548\uff08<a href=\"https:\/\/www.prnasia.com\/story\/525580-1.shtml\" target=\"_blank\" rel=\"noopener\">\u65b0\u95fb\u53d1\u5e03<\/a>\uff09\u3002\u5728\u540c\u4e00\u4e34\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cASC39\u5bf9\u4eba\u80f0\u6dc0\u7d201\u578b\u53d7\u4f53\uff08hAMY1R\uff09\u7684\u9009\u62e9\u6027\u6bd4\u4eba\u964d\u9499\u7d20\u53d7\u4f53\uff08hCTR\uff09\u9ad840\u500d\uff0c\u8fd9\u4e0eeloralintide\u5728\u76f8\u540c\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u7684\u9ad860\u500d\u7684\u9009\u62e9\u6027\u76f8\u5f53\u3002\u5728\u996e\u98df\u8bf1\u5bfc\u80a5\u80d6\uff08DIO\uff09\u5927\u9f20\u4e2d\uff0c\u8fde\u7eed\u516d\u5929\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u7ed9\u836f5mg\/kg ASC39\u5b9e\u73b0\u4e866.0%\u7684\u4f53\u91cd\u4e0b\u964d\uff0c\u4e0eeloralintide\uff085.0%\uff09\u76f8\u5f53\uff08\u88683\uff09\u3002ASC30_39FDC\uff0c<span>\u4e00\u6b3e<\/span>GLP-1\/\u80f0\u6dc0\u7d20\u53cc\u9776\u70b9\u6fc0\u52a8\u5242FDC\uff0c\u9884\u8ba1\u5c06\u6210\u4e3a\u8be5\u7c7b\u578b\u5168\u7403\u9996\u6b3e\u8fdb\u5165\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5<span>\uff08\u9884\u8ba1\u4e8e2026\u5e74\u7b2c\u56db\u5b63\u5ea6\uff09<\/span>\u7684<span>FDC\u3002<\/span><\/p>\n<p>\u88683. \u8fde\u7eed\u516d\u5929\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u7ed9\u836fASC39\u4e0e\u76ae\u4e0b\u6ce8\u5c04eloralintide\u5728\u80a5\u80d6\u5927\u9f20<span>\u4e2d\u7684\u5bf9\u6bd4<\/span>\u3002<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ec4\u522b<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ed9\u836f\u65b9\u6848<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u76f8\u8f83\u57fa\u7ebf\u7684\u603b\u4f53\u91cd\u53d8\u5316\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ecfeloralintide\u6cbb\u7597\u7684\u80a5\u80d6\u5927\u9f20\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">3 nmol\/kg,<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u76ae\u4e0b\uff0c\u6bcf\u4e09\u5929\u4e00\u6b21\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-5.0\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ecfASC39\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53(SARA)\uff09\u6cbb\u7597\u7684\u80a5\u80d6\u5927\u9f20<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">5 mg\/kg,<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u5929\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-6.0\u00a0%<\/span><\/p>\n<\/div>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6ce8\u91ca\uff1a\u80a5\u80d6\u5927\u9f20\uff1a\u996e\u98df\u8bf1\u5bfc\u80a5\u80d6\u5927\u9f20\u3002<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u590d\u65b9\u5236\u5242\uff08GLP-1\/GIP\uff09<\/p>\n<p>\u6b4c\u793c\u540c\u7c7b\u9996\u521b\u3001\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u9776\u5411GLP-1R\u548cGIPR\u7684\u53cc\u9776\u70b9\u6fc0\u52a8\u5242FDC\uff08ASC30_<span>48FDC<\/span>\uff09\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u7ed9\u836f\u516b\u5929\u540e\uff0c\u5b9e\u73b0\u4e8610.5%\u7684\u4f53\u91cd\u4e0b\u964d\u3002\u8fd9\u8f83ASC30\u5355\u836f\u6cbb\u7597\u7684\u51cf\u91cd\u6548\u679c\u76f8\u5bf9\u63d0\u534752%\uff08<a href=\"https:\/\/www.prnasia.com\/story\/540781-1.shtml\" target=\"_blank\" rel=\"noopener\">\u65b0\u95fb\u53d1\u5e03<\/a>\uff09\u3002\u5728\u4e00\u9879\u548c\u66ff\u5c14\u6cca\u80bd<span>\u7684<\/span>\u5934\u5bf9\u5934\u4f53\u5916\u7814\u7a76\u4e2d\uff0c\u540c\u7c7b\u9996\u521b\u7684\u53e3\u670d\u5c0f\u5206\u5b50GIPR\u6fc0\u52a8\u5242ASC48\u5728hGIPR \u73af\u78f7\u9178\u817a\u82f7\uff08cAMP\uff09\u6fc0\u6d3b\u5b9e\u9a8c\u4e2d\u7684EC50\u4e3a1 pM\uff0c\u5c55\u73b0\u51fa\u4f18\u4e8e\u66ff\u5c14\u6cca\u80bd\uff08\u66ff\u5c14\u6cca\u80bd\uff0cEC50 = 3 pM\uff09\u7684\u6fc0\u52a8\u6d3b\u6027\u3002ASC30_<span>48FDC<\/span>\u662f\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u7c7b\u4f3c\u4e8e\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\u6ce8\u5c04\u5242\uff08\u5982\u66ff\u5c14\u6cca\u80bd\uff09\u3002\u66ff\u5c14\u6cca\u80bd\u8bf4\u660e\u4e66\u663e\u793a\uff0c\u5176\u5728\u4eba\u4f53\u4e2d\u5b9e\u73b0\u4e86\u9ad8\u8fbe20.9%\u7684\u4f53\u91cd\u4e0b\u964d[2]\u3002<\/p>\n<p>\u88684. \u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u8fde\u7eed\u516b\u5929\u6bcf\u65e5\u4e00\u6b21\u53e3\u670dASC30_<span>48FDC<\/span><\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ec4\u522b<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7ed9\u836f\u65b9\u6848<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u76f8\u8f83\u57fa\u7ebf\u7684\u603b\u4f53\u91cd\u53d8\u5316\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC30 (GLP-1R)\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-6.9\u00a0%<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">ASC30_48FDC<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(GLP-1R\/GIPR)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2 mg\/kg ASC30<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u548c5 mg\/kg ASC48\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">-10.5\u00a0%<\/span><\/p>\n<\/div>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6ce8\u91ca\uff1aFDC\uff1a\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u3002<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>&#8220;\u8fd1\u671f\u6211\u4eec<span>\u6536\u5230\u4e86<\/span>FDA\u5bf9ASC30\u9879\u76eeend-of-Phase II<span>\u7684<\/span>\u79ef\u6781\u53cd\u9988\uff0c\u968f\u540e\u542f\u52a8\u4e86ASC30\u7684\u5168\u7403III\u671f\u9879\u76ee<span>\uff0c\u8fd9\u5f88\u4ee4\u4eba\u632f\u594b<\/span>\u3002ASC30\u662f\u6211\u4eec\u6bcf\u65e5\u4e00\u6b21\u3001\u6bcf\u6b21\u4e00\u7247\u53e3\u670d\u5c0f\u5206\u5b50\u80a5\u80d6\u75c7\u6cbb\u7597\u7ba1\u7ebf\u7ec4\u5408\u4e2d\u7684\u6838\u5fc3\u652f\u67f1\u3002&#8221;\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c&#8221;ASC30\uff08GLP-1\uff09\u3001ASC48\uff08GIP\uff09\u548cASC39\uff08\u80f0\u6dc0\u7d20SARA\uff09\u662f\u5177\u6709\u4e0d\u540c\u7406\u5316\u6027\u8d28\u7684\u5c0f\u5206\u5b50\u3002\u5728\u7814\u53d1\u8fd9\u4e9b\u5206\u5b50\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff08FDC\uff09\u8fc7\u7a0b\u4e2d\uff0c\u6211\u4eec\u5df2\u6210\u529f\u653b\u514b\u4e86\u8bf8\u591a\u6280\u672f\u6311\u6218\u3002\u6211\u4eec\u540c\u7c7b\u9996\u521b\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\uff08GLP-1\/GIP\/\u80f0\u6dc0\u7d20\uff09\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u7684\u6700\u65b0\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u5de9\u56fa\u4e86\u6211\u4eec\u5728\u884c\u4e1a\u4e2d\u9886\u5148\u7684\u3001\u5168\u9762\u7684\u3001\u5e76\u5177\u6709\u5dee\u5f02\u5316\u7684\u6bcf\u65e5\u4e00\u6b21\u3001\u6bcf\u6b21\u4e00\u7247\u53e3\u670d\u5c0f\u5206\u5b50\u7ba1\u7ebf\uff0c<span>\u7528\u4e8e<\/span>\u6cbb\u7597\u80a5\u80d6\u75c7\u548c\u5176\u4ed6\u4ee3\u8c22\u75be\u75c5\u3002&#8221;<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">[1] Eli Lilly and Company. Safety, tolerability, pharmacokinetics and pharmacodynamics of eloralintide and tirzepatide co-administered as once-weekly subcutaneous injections [<a href=\"https:\/\/cattendee.abstractsonline.com\/meeting\/21509\/presentation\/1535\" target=\"_blank\" class=\"prnews_a\" rel=\"noopener\">Abstract accepted for presentation at EASD 2026<\/a>]<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[2] ZEPBOUND (tirzepatide) injection, for subcutaneous use [US Prescribing Information]. Indianapolis, IN: Eli Lilly and Company. Section 14.1, Table 2 (Changes in Body Weight at Week 72 in Study 1)<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u5173\u4e8e\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>\n<p>\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\u662f\u4e00\u5bb6\u5168\u4ef7\u503c\u94fe\u6574\u5408\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u805a\u7126\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u4ee3\u8c22\u75be\u75c5\u540c\u7c7b\u6700\u4f73\uff08best-in-class\uff09\u548c\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u5229\u7528\u516c\u53f8\u4e13\u6709\u7684\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08Artificial Intelligence-assisted Structure-Based Drug Discovery\uff0cAISBDD\uff09\u3001\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08Ultra-Long-Acting Platform\uff0cULAP\uff09\u6280\u672f\u4ee5\u53ca\u53e3\u670d\u591a\u80bd\u9012\u9001\u589e\u5f3a\u6280\u672f\uff08Peptide Oral Transport ENhancement Technology\uff0cPOTENT\uff09\uff0c\u6b4c\u793c\u5df2\u81ea\u4e3b\u7814\u53d1\u591a\u6b3e\u5c0f\u5206\u5b50\u548c\u591a\u80bd\u5019\u9009\u836f\u7269\uff0c\u5305\u62ec\u5176\u6838\u5fc3\u9879\u76eeASC30\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50GLP-1R\u6fc0\u52a8\u5242\uff0c\u7528\u4e8e\u957f\u671f\u4f53\u91cd\u7ba1\u7406\u548c\u7cd6\u5c3f\u75c5\u6cbb\u7597\uff1bASC30_48FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u4e0eASC48\uff08GIPR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC30_48_39FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u3001ASC48\uff08GIPR\u6fc0\u52a8\u5242\uff09\u4e0eASC39\uff08\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC39\uff0c\u4e00\u6b3e\u4e0eeloralintide\u7c7b\u4f3c\u3001\u5f3a\u6548\u4e14\u5bf9\u80f0\u6dc0\u7d20\u5177\u6709\u9009\u62e9\u6027\u7684\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff1bASC30_39FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u4e0eASC39\uff08\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC36\uff0c\u4e00\u6b3e\u80f0\u6dc0\u7d20\u591a\u80bd\uff0c\u8bbe\u8ba1\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u4ee5\u53ca\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\uff1bASC35\uff0c\u4e00\u6b3e\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04GLP-1R\/GIPR\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff1bASC36_35FDC\uff0c\u4e00\u6b3e\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u4e09\u9776\u70b9\u591a\u80bd\u6fc0\u52a8\u5242\uff0c\u4e3aASC36\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\u4e0eASC35\uff08GLP-1R\/GIPR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC37\uff0c\u4e00\u6b3eGLP-1R\/GIPR\/GCGR\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u8bbe\u8ba1\u4e3a\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u53ca\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\uff1b\u4ee5\u53caASC36_37FD\uff09\uff0c\u4e00\u6b3e\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u56db\u9776\u70b9\u591a\u80bd\u6fc0\u52a8\u5242\uff0c\u4e3aASC36\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\u4e0eASC37\uff08GLP-1R\/GIPR\/GCGR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff0c\u7528\u4e8e\u957f\u671f\u4f53\u91cd\u7ba1\u7406\u3002\u6b4c\u793c\u5df2\u5728\u9999\u6e2f\u8054\u4ea4\u6240\u4e0a\u5e02\uff081672.HK\uff09\u3002<\/p>\n<p>\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8bf7\u767b\u5f55\u7f51\u7ad9\uff1a<a href=\"https:\/\/www.ascletis.com\/\" target=\"_blank\" rel=\"noopener\">www.ascletis.com<\/a>\u3002<\/p>\n<p><span>\u8be6\u60c5\u5782\u8be2\uff1a<\/span><br \/>Peter Vozzo<br \/>ICR Healthcare<br \/>443-231-0505 (\u7f8e\u56fd)<br \/><a href=\"mailto:Peter.vozzo@icrhealthcare.com\" target=\"_blank\" rel=\"noopener\">Peter.vozzo@icrhealthcare.com<\/a><\/p>\n<p>\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8PR\u548cIR\u56e2\u961f<br \/>+86-181-0650-9129 (\u4e2d\u56fd)<br \/><a href=\"mailto:pr@ascletis.com\" target=\"_blank\" rel=\"noopener\">pr@ascletis.com<\/a>\u00a0<br \/><a href=\"mailto:ir@ascletis.com\" target=\"_blank\" rel=\"noopener\">ir@ascletis.com<\/a>\u00a0<\/p>\n<p>SOURCE \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"<p>-GLP-1\u53e3\u670d\u5c0f\u5206\u5b50ASC30\u542f\u52a8\u5168\u7403III\u671f\u4e34\u5e8a\u9879\u76ee\uff0c\u5c06\u5728\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u52a0\u62ff\u5927\u5f00\u5c55\u4e24\u9879\u5173\u952e\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5c06\u5165\u7ec4\u7ea64,600\u540d\u80a5\u80d6\u6216\u8d85\u91cd\u53d7\u8bd5\u8005\u3002 -\u5ba3\u5e03\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50GLP-1\/GIP\/\u80f0\u6dc0\u7d20\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\u53d6\u5f97\u79ef\u6781\u7684\u4e34\u5e8a\u524d\u6570\u636e\u3002 -\u884c\u4e1a\u9886\u5148\u7684\u6bcf\u65e5\u4e00\u6b21\u3001\u6bcf\u6b21\u4e00\u7247\u53e3\u670d\u5c0f\u5206\u5b50\u80a5\u80d6\u75c7\u53ca\u5176\u4ed6\u4ee3\u8c22\u75be\u75c5\u7ba1\u7ebf\uff1a\u5305\u542b\u4e94\u6b3e\u8986\u76d6GLP-1\u3001GIP\u548c\u80f0\u6dc0\u7d20\u9776\u70b9\u7684\u5355\u836f\u53ca\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u4ea7\u54c1\u3002 -\u62e5\u6709\u5145\u8db3\u7684\u5728\u624b\u73b0\u91d1\uff0c\u8db3\u4ee5\u8986\u76d6\u9884\u8ba1\u4e8e2028\u5e74\u5e95\u5728\u7f8e\u56fd\u9012\u4ea4\u7684ASC30\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u4ee5\u53ca\u9884\u8ba1\u4e8e2029\u5e74\u521d\u5728\u6b27\u6d32\u9012\u4ea4\u7684ASC30\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08MAA\uff09\uff0c\u5e76\u53ef\u652f\u6301\u672c\u516c\u53f8\u8fd0\u8425\u81f32029\u5e74\u3002 \u9999\u6e2f2026\u5e748\u67083\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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