{"id":27258,"date":"2026-08-10T11:00:00","date_gmt":"2026-08-10T11:00:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e6%ad%8c%e7%a4%bc%e5%ae%a3%e5%b8%83%e5%9c%a8%e7%be%8e%e5%9b%bd%e5%90%af%e5%8a%a8%e4%b8%a4%e9%a1%b9%e6%b2%bb%e7%96%97%e8%82%a5%e8%83%96%e7%97%87%e7%9a%84i%e6%9c%9f%e7%a0%94%e7%a9%b6%ef%bc%9a%e8%83%b0\/"},"modified":"2026-08-10T11:00:00","modified_gmt":"2026-08-10T11:00:00","slug":"%e6%ad%8c%e7%a4%bc%e5%ae%a3%e5%b8%83%e5%9c%a8%e7%be%8e%e5%9b%bd%e5%90%af%e5%8a%a8%e4%b8%a4%e9%a1%b9%e6%b2%bb%e7%96%97%e8%82%a5%e8%83%96%e7%97%87%e7%9a%84i%e6%9c%9f%e7%a0%94%e7%a9%b6%ef%bc%9a%e8%83%b0","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e6%ad%8c%e7%a4%bc%e5%ae%a3%e5%b8%83%e5%9c%a8%e7%be%8e%e5%9b%bd%e5%90%af%e5%8a%a8%e4%b8%a4%e9%a1%b9%e6%b2%bb%e7%96%97%e8%82%a5%e8%83%96%e7%97%87%e7%9a%84i%e6%9c%9f%e7%a0%94%e7%a9%b6%ef%bc%9a%e8%83%b0\/","title":{"rendered":"\u6b4c\u793c\u5ba3\u5e03\u5728\u7f8e\u56fd\u542f\u52a8\u4e24\u9879\u6cbb\u7597\u80a5\u80d6\u75c7\u7684I\u671f\u7814\u7a76\uff1a\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bd\u6708\u6ce8\u5c04\u5242ASC36\u3001ASC36\u548cGLP-1R\/GIPR\u6fc0\u52a8\u5242\u591a\u80bdASC35\u7684\u590d\u65b9\u6708\u6ce8\u5c04\u5242ASC36_35FDC"},"content":{"rendered":"

-ASC36_35FDC\u662fASC36\u548cASC35\u7684\u76ae\u4e0b\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\uff08FDC\uff09\u6708\u6ce8\u5c04\u5242\uff0c\u6709\u671b\u6210\u4e3a\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u8fd9\u4e09\u4e2a\u5df2\u9a8c\u8bc1\u7684\u9776\u70b9\u7684\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u5019\u9009\u836f\u7269\u3002<\/p>\n

-ASC36\u6709\u671b\u6210\u4e3a\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u7684\u540c\u7c7b\u9996\u521b\u3001\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u5242\u3002<\/p>\n

-ASC36\u6ce8\u5c04\u5242\u4ee5\u53caASC36_35FDC\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff08IND\uff09\u4e8e\u8fd1\u671f\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u3002<\/p>\n

\u9999\u6e2f<\/span>2026\u5e748\u670810\u65e5<\/span> \/\u7f8e\u901a\u793e\/ —\u00a0\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a1672\uff0c\u7b80\u79f0”\u6b4c\u793c”\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u5728\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff08IND\uff09\u6279\u51c6\u540e\uff0c\u5176\u5df2\u5728\u7f8e\u56fd\u542f\u52a8\u4e86\u4e24\u9879\u6cbb\u7597\u80a5\u80d6\u75c7\u7684I\u671f\u7814\u7a76\uff1a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u7684\u65b0\u4e00\u4ee3\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bdASC36\uff0c\u4ee5\u53caASC36\u548cGLP-1R\/GIPR\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bdASC35\u7684\u76ae\u4e0b\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\uff08FDC\uff09\u6708\u6ce8\u5c04\u5242ASC36_35FDC\u3002<\/p>\n

\n<\/div>\n

ASC36_35FDC\u7684\u8be5I\u671f\u7814\u7a76\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30ASC36_35FDC\u6ce8\u5c04\u5242\u5728\u80a5\u80d6\uff08\u4f53\u91cd\u6307\u6570\uff08BMI\uff09\u226530.0 kg\/m\u00b2\uff09\u6216\u4f34\u6709\u4f53\u91cd\u76f8\u5173\u5408\u5e76\u75c7\u7684\u8d85\u91cd\uff08BMI\u226527.0 kg\/m\u00b2\uff09\u53d7\u8bd5\u8005\u4e2d\uff0c\u5355\u5242\u91cf\u548c\u591a\u5242\u91cf\u9012\u589e\u7ed9\u836f\u540e\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u836f\u6548\u52a8\u529b\u5b66\u3002\u8be5I\u671f\u7814\u7a76\u8fd8\u5c06\u8bc4\u4f30\u4e24\u6b3e\u4e0d\u540c\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\uff08FDC\uff09\u5236\u5242\uff1a\u6ce8\u5c04\u5242A\u572888\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\uff0c\u6ce8\u5c04\u5242B\u572888\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\u3002\u6ce8\u5c04\u5242A\u548cB\u5747\u7531\u4e24\u6b3e\u8d85\u957f\u6548\u6fc0\u52a8\u5242\u591a\u80bd\u7ec4\u6210\uff1a\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bdASC36\u548cGLP-1R\/GIPR\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bdASC35\u3002<\/p>\n

ASC36\u7684\u8be5I\u671f\u8bd5\u9a8c\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30ASC36\u6ce8\u5c04\u5242\u5728\u80a5\u80d6\uff08BMI\u226530.0 kg\/m\u00b2\uff09\u6216\u4f34\u6709\u4f53\u91cd\u76f8\u5173\u5408\u5e76\u75c7\u7684\u8d85\u91cd\uff08BMI\u226527.0 kg\/m\u00b2\uff09\u53d7\u8bd5\u8005\u4e2d\uff0c\u5355\u5242\u91cf\u548c\u591a\u5242\u91cf\u9012\u589e\u7ed9\u836f\u540e\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u836f\u6548\u52a8\u529b\u5b66\u3002\u8be5I\u671f\u7814\u7a76\u8fd8\u5c06\u8bc4\u4f30\u4e24\u6b3e\u4e0d\u540c\u7684\u5236\u5242\uff1a\u6ce8\u5c04\u5242A\u572872\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\uff0c\u6ce8\u5c04\u5242B\u572872\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\u3002<\/p>\n

“Eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u8fd1\u671f\u6570\u636e\u663e\u793a\uff0c\u5728\u7b2c32\u5468\u65f6\u4f53\u91cd\u4e0b\u964d\u4e3a29.0%[1]\u3002\u7136\u800c\uff0c\u8be5\u65b9\u6848\u9700\u8981\u6bcf\u5468\u6ce8\u5c04\u4e24\u9488\uff0c\u4e00\u9488eloralintide\uff0c\u53e6\u4e00\u9488\u66ff\u5c14\u6cca\u80bd\u3002\u8fd9\u76f8\u5f53\u4e8e\u6bcf\u6708\u6ce8\u5c04\u516b\u9488\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u6709\u671b\u6210\u4e3a\u540c\u7c7b\u9996\u521b\u3001\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u7684\u76ae\u4e0b\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u6ce8\u5c04\u5242ASC36_35FDC\uff0c\u6bcf\u6708\u4ec5\u9700\u6ce8\u5c04\u4e00\u9488\u3002\u66f4\u4ee4\u4eba\u632f\u594b\u7684\u662f\uff0c\u5728\u5934\u5bf9\u5934\u996e\u98df\u8bf1\u5bfc\u80a5\u80d6\uff08DIO\uff09\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u7684\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\uff08<\/span>\u65b0\u95fb\u53d1\u5e03<\/a>\uff09\u3002\u8fd9\u4e9b\u52a8\u7269\u6a21\u578b\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\u3002”\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c”\u968f\u7740\u6211\u4eec\u542f\u52a8GLP-1\u53e3\u670d\u5c0f\u5206\u5b50ASC30\u7684\u5168\u7403III\u671f\u4e34\u5e8a\u9879\u76ee\uff0c\u6211\u5bf9\u6211\u4eec2026\u5e74\u5728\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u591a\u80bd\u7ba1\u7ebf\u4e0a\u53d6\u5f97\u7684\u91cd\u5927\u8fdb\u5c55\u540c\u6837\u611f\u5230\u9ad8\u5174\uff0c\u8fd9\u4e9b\u8fdb\u5c55\u4f53\u73b0\u5728\u6211\u4eec\u5728\u7f8e\u56fd\u542f\u52a8\u4e86\u4e09\u9879I\u671f\u7814\u7a76\uff1aASC35\u3001ASC36\u548cASC36_35FDC\u3002”<\/p>\n

ASC36\u548cASC35\u5747\u662f\u6b4c\u793c\u5229\u7528\u5176\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08AISBDD\uff09\u6280\u672f\u81ea\u4e3b\u7814\u53d1\u7684\u3002ASC36\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u5236\u5242\u4ee5\u53caASC36_35FDC\u6bcf\u6708\u4e00\u6b21\u590d\u65b9\u5236\u5242\u5747\u4e3a\u81ea\u7ec4\u88c5\u8102\u8d28\u50a8\u5e93\u578b\uff08SALD\uff09\u5236\u5242\uff0c\u7531\u6b4c\u793c\u5229\u7528\u5176\u4e13\u6709\u7684\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08ULAP\uff09\u6280\u672f\u81ea\u4e3b\u5f00\u53d1\u3002<\/p>\n

SALD\u5236\u5242\u662f\u4e00\u79cd\u4f4e\u7c98\u5ea6\u6eb6\u6db2\uff0c\u7531\u8102\u8d28\u3001\u5177\u6709\u751f\u7269\u76f8\u5bb9\u6027\u7684\u6709\u673a\u6eb6\u5242\u548c\u6d3b\u6027\u836f\u7269\u6210\u5206\uff08API\uff09\u7ec4\u6210\u3002\u8be5\u4f4e\u7c98\u5ea6\u6eb6\u6db2\u53ef\u4ee5\u4f7f\u7528\u914d\u6709\u7ec6\u81f329G\uff08gauge\uff09\u9488\u5934\u7684\u6ce8\u5c04\u7b14\u6216\u81ea\u52a8\u6ce8\u5c04\u5668\uff0c\u8f7b\u677e\u6ce8\u5165\u76ae\u4e0b\u7ec4\u7ec7\u3002\u76ae\u4e0b\u6ce8\u5c04\u540e\uff0c\u8be5\u6eb6\u6db2\u5728\u7ec4\u7ec7\u4e2d\u4f1a\u8f6c\u5316\u4e3a\u51dd\u80f6\u72b6\u7684\u50a8\u5e93\uff08depot\uff09\u3002\u5728\u7ec4\u7ec7\u5185\u9176\u7684\u4f5c\u7528\u4e0b\uff0c\u8be5\u50a8\u5e93\u4f1a\u7f13\u6162\u964d\u89e3\uff0c\u4ece\u800c\u63a7\u5236API\u5728\u4e00\u4e2a\u6708\u6216\u66f4\u957f\u7684\u65f6\u95f4\u5185\u6301\u7eed\u91ca\u653e\u3002<\/p>\n

\u5728\u5934\u5bf9\u5934\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36 SALD\u5236\u5242\u7684\u8868\u89c2\u534a\u8870\u671f\uff08observed half-life\uff09\u7ea6\u4e3aeloralintide\u76846\u500d\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36\u548cASC35\u5728ASC36_35FDC SALD\u590d\u65b9\u5236\u5242\u4e2d\u5747\u8868\u73b0\u51fa\u4e86\u8f83\u957f\u7684\u8868\u89c2\u534a\u8870\u671f\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002<\/p>\n

\u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u786e\u7acb\u4e86ASC36\u6ce8\u5c04\u5242\u53caASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u7684\u4f18\u8d8a\u7597\u6548\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff08\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\uff09\uff0c\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u7684ASC36\u5355\u836f\u8f83petrelintide\u5355\u836f\u548celoralintide\u5355\u836f\u7684\u51cf\u91cd\u6548\u679c\u5206\u522b\u76f8\u5bf9\u63d0\u5347\u7ea691%\u548c32%\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u4e09\u4e2a\u9776\u70b9\uff0c\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\u3002<\/p>\n

ASC36\u6ce8\u5c04\u5242\u548cASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u5747\u5177\u6709\u4f18\u8d8a\u7684\u7406\u5316\u7a33\u5b9a\u6027\uff0c\u5728\u4e2d\u6027pH\u503c\u9644\u8fd1\u6ca1\u6709\u7ea4\u7ef4\u5316\u5bfc\u81f4\u7684\u805a\u96c6\u6c89\u6dc0\u3002<\/p>\n

\n

[1] Eli Lilly and Company. Safety, tolerability, pharmacokinetics and pharmacodynamics of eloralintide and tirzepatide co-administered as once-weekly subcutaneous injections [Abstract accepted for presentation at EASD 2026<\/a>]<\/span><\/p>\n<\/div>\n

\u00a0<\/p>\n

\u5173\u4e8e\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>\n

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\u8be6\u60c5\u5782\u8be2\uff1a<\/p>\n

Peter Vozzo
ICR Healthcare
443-231-0505 (\u7f8e\u56fd)
Peter.vozzo@icrhealthcare.com<\/a>\u00a0<\/p>\n

\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8PR\u548cIR\u56e2\u961f
+86-181-0650-9129 (\u4e2d\u56fd)
pr@ascletis.com<\/a>
ir@ascletis.com<\/a>\u00a0<\/p>\n

\u00a0<\/p>\n

SOURCE \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"

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“Eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u8fd1\u671f\u6570\u636e\u663e\u793a\uff0c\u5728\u7b2c32\u5468\u65f6\u4f53\u91cd\u4e0b\u964d\u4e3a29.0%[1]\u3002\u7136\u800c\uff0c\u8be5\u65b9\u6848\u9700\u8981\u6bcf\u5468\u6ce8\u5c04\u4e24\u9488\uff0c\u4e00\u9488eloralintide\uff0c\u53e6\u4e00\u9488\u66ff\u5c14\u6cca\u80bd\u3002\u8fd9\u76f8\u5f53\u4e8e\u6bcf\u6708\u6ce8\u5c04\u516b\u9488\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u6709\u671b\u6210\u4e3a\u540c\u7c7b\u9996\u521b\u3001\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u7684\u76ae\u4e0b\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u6ce8\u5c04\u5242ASC36_35FDC\uff0c\u6bcf\u6708\u4ec5\u9700\u6ce8\u5c04\u4e00\u9488\u3002\u66f4\u4ee4\u4eba\u632f\u594b\u7684\u662f\uff0c\u5728\u5934\u5bf9\u5934\u996e\u98df\u8bf1\u5bfc\u80a5\u80d6\uff08DIO\uff09\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u7684\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\uff08\u65b0\u95fb\u53d1\u5e03\uff09\u3002\u8fd9\u4e9b\u52a8\u7269\u6a21\u578b\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\u3002”\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c”\u968f\u7740\u6211\u4eec\u542f\u52a8GLP-1\u53e3\u670d\u5c0f\u5206\u5b50ASC30\u7684\u5168\u7403III\u671f\u4e34\u5e8a\u9879\u76ee\uff0c\u6211\u5bf9\u6211\u4eec2026\u5e74\u5728\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u591a\u80bd\u7ba1\u7ebf\u4e0a\u53d6\u5f97\u7684\u91cd\u5927\u8fdb\u5c55\u540c\u6837\u611f\u5230\u9ad8\u5174\uff0c\u8fd9\u4e9b\u8fdb\u5c55\u4f53\u73b0\u5728\u6211\u4eec\u5728\u7f8e\u56fd\u542f\u52a8\u4e86\u4e09\u9879I\u671f\u7814\u7a76\uff1aASC35\u3001ASC36\u548cASC36_35FDC\u3002” ASC36\u548cASC35\u5747\u662f\u6b4c\u793c\u5229\u7528\u5176\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08AISBDD\uff09\u6280\u672f\u81ea\u4e3b\u7814\u53d1\u7684\u3002ASC36\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u5236\u5242\u4ee5\u53caASC36_35FDC\u6bcf\u6708\u4e00\u6b21\u590d\u65b9\u5236\u5242\u5747\u4e3a\u81ea\u7ec4\u88c5\u8102\u8d28\u50a8\u5e93\u578b\uff08SALD\uff09\u5236\u5242\uff0c\u7531\u6b4c\u793c\u5229\u7528\u5176\u4e13\u6709\u7684\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08ULAP\uff09\u6280\u672f\u81ea\u4e3b\u5f00\u53d1\u3002 SALD\u5236\u5242\u662f\u4e00\u79cd\u4f4e\u7c98\u5ea6\u6eb6\u6db2\uff0c\u7531\u8102\u8d28\u3001\u5177\u6709\u751f\u7269\u76f8\u5bb9\u6027\u7684\u6709\u673a\u6eb6\u5242\u548c\u6d3b\u6027\u836f\u7269\u6210\u5206\uff08API\uff09\u7ec4\u6210\u3002\u8be5\u4f4e\u7c98\u5ea6\u6eb6\u6db2\u53ef\u4ee5\u4f7f\u7528\u914d\u6709\u7ec6\u81f329G\uff08gauge\uff09\u9488\u5934\u7684\u6ce8\u5c04\u7b14\u6216\u81ea\u52a8\u6ce8\u5c04\u5668\uff0c\u8f7b\u677e\u6ce8\u5165\u76ae\u4e0b\u7ec4\u7ec7\u3002\u76ae\u4e0b\u6ce8\u5c04\u540e\uff0c\u8be5\u6eb6\u6db2\u5728\u7ec4\u7ec7\u4e2d\u4f1a\u8f6c\u5316\u4e3a\u51dd\u80f6\u72b6\u7684\u50a8\u5e93\uff08depot\uff09\u3002\u5728\u7ec4\u7ec7\u5185\u9176\u7684\u4f5c\u7528\u4e0b\uff0c\u8be5\u50a8\u5e93\u4f1a\u7f13\u6162\u964d\u89e3\uff0c\u4ece\u800c\u63a7\u5236API\u5728\u4e00\u4e2a\u6708\u6216\u66f4\u957f\u7684\u65f6\u95f4\u5185\u6301\u7eed\u91ca\u653e\u3002 \u5728\u5934\u5bf9\u5934\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36 SALD\u5236\u5242\u7684\u8868\u89c2\u534a\u8870\u671f\uff08observed half-life\uff09\u7ea6\u4e3aeloralintide\u76846\u500d\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36\u548cASC35\u5728ASC36_35FDC SALD\u590d\u65b9\u5236\u5242\u4e2d\u5747\u8868\u73b0\u51fa\u4e86\u8f83\u957f\u7684\u8868\u89c2\u534a\u8870\u671f\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002 \u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u786e\u7acb\u4e86ASC36\u6ce8\u5c04\u5242\u53caASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u7684\u4f18\u8d8a\u7597\u6548\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff08\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\uff09\uff0c\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u7684ASC36\u5355\u836f\u8f83petrelintide\u5355\u836f\u548celoralintide\u5355\u836f\u7684\u51cf\u91cd\u6548\u679c\u5206\u522b\u76f8\u5bf9\u63d0\u5347\u7ea691%\u548c32%\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u4e09\u4e2a\u9776\u70b9\uff0c\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\u3002 ASC36\u6ce8\u5c04\u5242\u548cASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u5747\u5177\u6709\u4f18\u8d8a\u7684\u7406\u5316\u7a33\u5b9a\u6027\uff0c\u5728\u4e2d\u6027pH\u503c\u9644\u8fd1\u6ca1\u6709\u7ea4\u7ef4\u5316\u5bfc\u81f4\u7684\u805a\u96c6\u6c89\u6dc0\u3002 [1] Eli Lilly and Company. Safety, tolerability, pharmacokinetics and pharmacodynamics of eloralintide and tirzepatide co-administered as once-weekly subcutaneous injections [Abstract accepted for presentation at EASD 2026] \u00a0 \u5173\u4e8e\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8 \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\u662f\u4e00\u5bb6\u5168\u4ef7\u503c\u94fe\u6574\u5408\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u805a\u7126\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u4ee3\u8c22\u75be\u75c5\u540c\u7c7b\u6700\u4f73\uff08best-in-class\uff09\u548c\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u5229\u7528\u516c\u53f8\u4e13\u6709\u7684\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08Artificial Intelligence-assisted Structure-Based Drug Discovery\uff0cAISBDD\uff09\u3001\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08Ultra-Long-Acting Platform\uff0cULAP\uff09\u6280\u672f\u4ee5\u53ca\u53e3\u670d\u591a\u80bd\u9012\u9001\u589e\u5f3a\u6280\u672f\uff08Peptide […]<\/p>\n","protected":false},"author":0,"featured_media":27259,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-27258","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\n\u6b4c\u793c\u5ba3\u5e03\u5728\u7f8e\u56fd\u542f\u52a8\u4e24\u9879\u6cbb\u7597\u80a5\u80d6\u75c7\u7684I\u671f\u7814\u7a76\uff1a\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bd\u6708\u6ce8\u5c04\u5242ASC36\u3001ASC36\u548cGLP-1R\/GIPR\u6fc0\u52a8\u5242\u591a\u80bdASC35\u7684\u590d\u65b9\u6708\u6ce8\u5c04\u5242ASC36_35FDC - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u6b4c\u793c\u5ba3\u5e03\u5728\u7f8e\u56fd\u542f\u52a8\u4e24\u9879\u6cbb\u7597\u80a5\u80d6\u75c7\u7684i\u671f\u7814\u7a76\uff1a\u80f0\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u6b4c\u793c\u5ba3\u5e03\u5728\u7f8e\u56fd\u542f\u52a8\u4e24\u9879\u6cbb\u7597\u80a5\u80d6\u75c7\u7684I\u671f\u7814\u7a76\uff1a\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bd\u6708\u6ce8\u5c04\u5242ASC36\u3001ASC36\u548cGLP-1R\/GIPR\u6fc0\u52a8\u5242\u591a\u80bdASC35\u7684\u590d\u65b9\u6708\u6ce8\u5c04\u5242ASC36_35FDC - Money Compass CN\" \/>\n<meta property=\"og:description\" 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ASC36_35FDC\u7684\u8be5I\u671f\u7814\u7a76\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30ASC36_35FDC\u6ce8\u5c04\u5242\u5728\u80a5\u80d6\uff08\u4f53\u91cd\u6307\u6570\uff08BMI\uff09\u226530.0 kg\/m\u00b2\uff09\u6216\u4f34\u6709\u4f53\u91cd\u76f8\u5173\u5408\u5e76\u75c7\u7684\u8d85\u91cd\uff08BMI\u226527.0 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ASC36\u7684\u8be5I\u671f\u8bd5\u9a8c\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30ASC36\u6ce8\u5c04\u5242\u5728\u80a5\u80d6\uff08BMI\u226530.0 kg\/m\u00b2\uff09\u6216\u4f34\u6709\u4f53\u91cd\u76f8\u5173\u5408\u5e76\u75c7\u7684\u8d85\u91cd\uff08BMI\u226527.0 kg\/m\u00b2\uff09\u53d7\u8bd5\u8005\u4e2d\uff0c\u5355\u5242\u91cf\u548c\u591a\u5242\u91cf\u9012\u589e\u7ed9\u836f\u540e\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u836f\u6548\u52a8\u529b\u5b66\u3002\u8be5I\u671f\u7814\u7a76\u8fd8\u5c06\u8bc4\u4f30\u4e24\u6b3e\u4e0d\u540c\u7684\u5236\u5242\uff1a\u6ce8\u5c04\u5242A\u572872\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\uff0c\u6ce8\u5c04\u5242B\u572872\u540d\u53d7\u8bd5\u8005\u4e2d\u8fdb\u884c\u3002 “Eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u8fd1\u671f\u6570\u636e\u663e\u793a\uff0c\u5728\u7b2c32\u5468\u65f6\u4f53\u91cd\u4e0b\u964d\u4e3a29.0%[1]\u3002\u7136\u800c\uff0c\u8be5\u65b9\u6848\u9700\u8981\u6bcf\u5468\u6ce8\u5c04\u4e24\u9488\uff0c\u4e00\u9488eloralintide\uff0c\u53e6\u4e00\u9488\u66ff\u5c14\u6cca\u80bd\u3002\u8fd9\u76f8\u5f53\u4e8e\u6bcf\u6708\u6ce8\u5c04\u516b\u9488\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u6709\u671b\u6210\u4e3a\u540c\u7c7b\u9996\u521b\u3001\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u7684\u76ae\u4e0b\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u6ce8\u5c04\u5242ASC36_35FDC\uff0c\u6bcf\u6708\u4ec5\u9700\u6ce8\u5c04\u4e00\u9488\u3002\u66f4\u4ee4\u4eba\u632f\u594b\u7684\u662f\uff0c\u5728\u5934\u5bf9\u5934\u996e\u98df\u8bf1\u5bfc\u80a5\u80d6\uff08DIO\uff09\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u7684\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\uff08\u65b0\u95fb\u53d1\u5e03\uff09\u3002\u8fd9\u4e9b\u52a8\u7269\u6a21\u578b\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\u3002”\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c”\u968f\u7740\u6211\u4eec\u542f\u52a8GLP-1\u53e3\u670d\u5c0f\u5206\u5b50ASC30\u7684\u5168\u7403III\u671f\u4e34\u5e8a\u9879\u76ee\uff0c\u6211\u5bf9\u6211\u4eec2026\u5e74\u5728\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\u591a\u80bd\u7ba1\u7ebf\u4e0a\u53d6\u5f97\u7684\u91cd\u5927\u8fdb\u5c55\u540c\u6837\u611f\u5230\u9ad8\u5174\uff0c\u8fd9\u4e9b\u8fdb\u5c55\u4f53\u73b0\u5728\u6211\u4eec\u5728\u7f8e\u56fd\u542f\u52a8\u4e86\u4e09\u9879I\u671f\u7814\u7a76\uff1aASC35\u3001ASC36\u548cASC36_35FDC\u3002” ASC36\u548cASC35\u5747\u662f\u6b4c\u793c\u5229\u7528\u5176\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08AISBDD\uff09\u6280\u672f\u81ea\u4e3b\u7814\u53d1\u7684\u3002ASC36\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u5236\u5242\u4ee5\u53caASC36_35FDC\u6bcf\u6708\u4e00\u6b21\u590d\u65b9\u5236\u5242\u5747\u4e3a\u81ea\u7ec4\u88c5\u8102\u8d28\u50a8\u5e93\u578b\uff08SALD\uff09\u5236\u5242\uff0c\u7531\u6b4c\u793c\u5229\u7528\u5176\u4e13\u6709\u7684\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08ULAP\uff09\u6280\u672f\u81ea\u4e3b\u5f00\u53d1\u3002 SALD\u5236\u5242\u662f\u4e00\u79cd\u4f4e\u7c98\u5ea6\u6eb6\u6db2\uff0c\u7531\u8102\u8d28\u3001\u5177\u6709\u751f\u7269\u76f8\u5bb9\u6027\u7684\u6709\u673a\u6eb6\u5242\u548c\u6d3b\u6027\u836f\u7269\u6210\u5206\uff08API\uff09\u7ec4\u6210\u3002\u8be5\u4f4e\u7c98\u5ea6\u6eb6\u6db2\u53ef\u4ee5\u4f7f\u7528\u914d\u6709\u7ec6\u81f329G\uff08gauge\uff09\u9488\u5934\u7684\u6ce8\u5c04\u7b14\u6216\u81ea\u52a8\u6ce8\u5c04\u5668\uff0c\u8f7b\u677e\u6ce8\u5165\u76ae\u4e0b\u7ec4\u7ec7\u3002\u76ae\u4e0b\u6ce8\u5c04\u540e\uff0c\u8be5\u6eb6\u6db2\u5728\u7ec4\u7ec7\u4e2d\u4f1a\u8f6c\u5316\u4e3a\u51dd\u80f6\u72b6\u7684\u50a8\u5e93\uff08depot\uff09\u3002\u5728\u7ec4\u7ec7\u5185\u9176\u7684\u4f5c\u7528\u4e0b\uff0c\u8be5\u50a8\u5e93\u4f1a\u7f13\u6162\u964d\u89e3\uff0c\u4ece\u800c\u63a7\u5236API\u5728\u4e00\u4e2a\u6708\u6216\u66f4\u957f\u7684\u65f6\u95f4\u5185\u6301\u7eed\u91ca\u653e\u3002 \u5728\u5934\u5bf9\u5934\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36 SALD\u5236\u5242\u7684\u8868\u89c2\u534a\u8870\u671f\uff08observed half-life\uff09\u7ea6\u4e3aeloralintide\u76846\u500d\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7814\u7a76\u4e2d\uff0cASC36\u548cASC35\u5728ASC36_35FDC SALD\u590d\u65b9\u5236\u5242\u4e2d\u5747\u8868\u73b0\u51fa\u4e86\u8f83\u957f\u7684\u8868\u89c2\u534a\u8870\u671f\uff0c\u652f\u6301\u5728\u4eba\u4f53\u4e2d\u6bcf\u6708\u4e00\u6b21\u76ae\u4e0b\u7ed9\u836f\u3002 \u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u786e\u7acb\u4e86ASC36\u6ce8\u5c04\u5242\u53caASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u7684\u4f18\u8d8a\u7597\u6548\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff08\u5bf9\u4eba\u4f53\u7597\u6548\u5177\u6709\u9ad8\u5ea6\u9884\u6d4b\u6027\uff09\uff0c\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u7684ASC36\u5355\u836f\u8f83petrelintide\u5355\u836f\u548celoralintide\u5355\u836f\u7684\u51cf\u91cd\u6548\u679c\u5206\u522b\u76f8\u5bf9\u63d0\u5347\u7ea691%\u548c32%\u3002\u5728\u5934\u5bf9\u5934DIO\u5927\u9f20\u7814\u7a76\u4e2d\uff0cASC36_35FDC\u9776\u5411\u80f0\u6dc0\u7d20\u53d7\u4f53\u3001GLP-1R\u548cGIPR\u4e09\u4e2a\u9776\u70b9\uff0c\u51cf\u91cd\u6548\u679c\u8f83eloralintide\u8054\u5408\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u63d0\u5347\u7ea651%\u3002 ASC36\u6ce8\u5c04\u5242\u548cASC36_35FDC\u590d\u65b9\u6ce8\u5c04\u5242\u5747\u5177\u6709\u4f18\u8d8a\u7684\u7406\u5316\u7a33\u5b9a\u6027\uff0c\u5728\u4e2d\u6027pH\u503c\u9644\u8fd1\u6ca1\u6709\u7ea4\u7ef4\u5316\u5bfc\u81f4\u7684\u805a\u96c6\u6c89\u6dc0\u3002 [1] Eli Lilly and Company. Safety, tolerability, pharmacokinetics and pharmacodynamics of eloralintide and tirzepatide co-administered as once-weekly subcutaneous injections [Abstract accepted for presentation at EASD 2026] \u00a0 \u5173\u4e8e\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8 \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\u662f\u4e00\u5bb6\u5168\u4ef7\u503c\u94fe\u6574\u5408\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u805a\u7126\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u4ee3\u8c22\u75be\u75c5\u540c\u7c7b\u6700\u4f73\uff08best-in-class\uff09\u548c\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u5229\u7528\u516c\u53f8\u4e13\u6709\u7684\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08Artificial Intelligence-assisted Structure-Based Drug Discovery\uff0cAISBDD\uff09\u3001\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08Ultra-Long-Acting 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