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FDC\u4e2d\u7684\u7ea68.3\u5929\u3002ASC36o\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u4e5f\u6709\u6240\u63d0\u5347\uff0c\u4ece\u5355\u836f\u65f6\u76846%\u81f38%\u63d0\u5347\u81f3\u4e24\u6b3eFDC\u4e2d\u7684\u5747\u226510%\uff08\u88682\uff09\u3002<\/p>\n<p class=\"prntaj\">\u6b64\u5916\uff0c\u516c\u53f8\u7684\u7ba1\u7ebf\u5305\u62ec\u6bcf\u5468\u4e00\u6b21\u53e3\u670dGLP-1\/GIP\/GCG\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bdASC37o\u548c\u6bcf\u5468\u4e00\u6b21\u53e3\u670dGLP-1\/GIP\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bdASC35o\uff08\u88681\uff09\u3002\u8be5\u7ba1\u7ebf\u8d4b\u4e88\u4e86\u6b4c\u793c\u72ec\u7279\u7684\u7ade\u4e89\u5730\u4f4d\uff0c\u80fd\u591f\u5927\u5e45\u62d3\u5c55\u9002\u7528\u53e3\u670d\u836f\u7269\u6cbb\u7597\u7684\u4eba\u7fa4\u3002<\/p>\n<p class=\"prntaj\">\u4e1a\u5185\u9886\u5148\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\uff0c\u8986\u76d6\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u7ba1\u7ebf<\/p>\n<p class=\"prntaj\">\u6b4c\u793c\u7684\u6240\u6709\u4e94\u6b3e\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\/\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u5747\u91c7\u7528\u6b4c\u793c\u4e13\u6709\u7684\u53e3\u670d\u591a\u80bd\u9012\u9001\u589e\u5f3a\u6280\u672f\uff08POTENT\uff09\u3002\u5728\u72ac\u548c\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\uff0cPOTENT\u5747\u901a\u8fc7\u80c3\u90e8\u548c\u80a0\u9053\u7684\u53cc\u91cd\u5438\u6536\u63d0\u9ad8\u4e86\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u3002POTENT\u4e5f\u663e\u8457\u964d\u4f4e\u4e86\u53e3\u670d\u7ed9\u836f\u540e\u53d7\u8bd5\u5bf9\u8c61\u81ea\u8eab\u53ca\u53d7\u8bd5\u5bf9\u8c61\u95f4\u7684\u5dee\u5f02\uff08variability\uff09\u3002\u8fd9\u9879\u6280\u672f\u4f7f\u6b4c\u793c\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u4e2d\uff0c\u7a33\u6001\u4e0b\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u9ad8\u8fbe10%\u4ee5\u4e0a\uff0c\u4ee5\u53ca\u534a\u8870\u671f\u957f\u8fbe\u7ea68.8\u5929\uff08\u88682\uff09\u3002\u8fd9\u4e9b\u9ad8\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u4e0e\u8d85\u957f\u534a\u8870\u671f\u76f8\u7ed3\u5408\uff0c\u4e3a\u5176\u53e3\u670d\u591a\u80bd\u6bcf\u5468\u4e00\u6b21\u7ed9\u836f\u63d0\u4f9b\u4e86\u5546\u4e1a\u5316\u53ef\u884c\u6027\u3002<\/p>\n<p class=\"prntaj\">\u88682. \u53e3\u670d\u591a\u80bd\u7ec4\u5408\u5728NHP\u4e2d\u7a33\u6001\u4e0b\u7684\u534a\u8870\u671f\u548c\u751f\u7269\u5229\u7528\u5ea6<\/p>\n<div>\n<p class=\"prngen8\"><span class=\"prnews_span\">\u7247\u5242<\/span><\/p>\n<p class=\"prngen8\"><span class=\"prnews_span\">\u534a\u8870\u671f<\/span><\/p>\n<p class=\"prngen8\"><span class=\"prnews_span\">\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36o<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">\u9ad8\u8fbe167\u5c0f\u65f6\uff08\u7ea67\u5929\uff09<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">6% \u81f3 8%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36_37o FDC<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36\uff1a\u9ad8\u8fbe200 \u5c0f\u65f6 (\u7ea68.3\u5929)<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC37\uff1a\u9ad8\u8fbe96 \u5c0f\u65f6 (4\u5929)<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36: &gt;10%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC37: \u22659.1%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36_35o FDC<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36\uff1a\u9ad8\u8fbe212 \u5c0f\u65f6 (\u7ea68.8\u5929)<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC35\uff1a\u9ad8\u8fbe158 \u5c0f\u65f6 (\u7ea66.6\u5929)<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC36: \u226510%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC35: \u22659.3%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC37o<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">\u9ad8\u8fbe79\u5c0f\u65f6\uff08\u7ea63.3\u5929\uff09<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">3.5% \u81f3 7.9%<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">ASC35o<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">\u9ad8\u8fbe83\u5c0f\u65f6\uff08\u7ea63.5\u5929\uff09<\/span><\/p>\n<p class=\"prngen9\"><span class=\"prnews_span\">\u4e0eASC37o\u76f8\u4f3c<\/span><\/p>\n<\/div>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6ce8\u91ca\uff1a<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">NHP\uff1a\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\uff1bFDC\uff1a\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u3002<\/span><\/p>\n<p><\/p><\/div>\n<p class=\"prntaj\">&#8220;\u968f\u7740\u7f8e\u56fdI\u671f\u7814\u7a76\u7684\u5f00\u5c55\uff0c\u6211\u4eec\u7684\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u5e73\u53f0\u8de8\u8d8a\u4e86\u53c8\u4e00\u91cc\u7a0b\u7891\u3002&#8221;\u6b4c\u793c\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u5434\u52b2\u6893\u535a\u58eb\u8868\u793a\uff0c&#8221;\u636e\u6211\u4eec\u6240\u77e5\uff0c\u6211\u4eec\u7684\u4e24\u6b3eFDC\u7247\u662f\u9996\u6279\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\u3002\u8fde\u540cASC37o\u548cASC35o\uff0c\u6b4c\u793c\u7531\u6b64\u6784\u5efa\u4e86\u6211\u4eec\u8ba4\u4e3a\u4e1a\u5185\u6700\u5168\u9762\u7684\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u7ba1\u7ebf\uff0c\u5168\u9762\u8986\u76d6\u80f0\u6dc0\u7d20\u3001GLP-1\u3001GIP\u548c\u80f0\u9ad8\u8840\u7cd6\u7d20\u53d7\u4f53\u8fd9\u56db\u4e2a\u5df2\u9a8c\u8bc1\u7684\u9776\u70b9\u3002\u6211\u4eec\u7684POTENT\u5e73\u53f0\u4fc3\u8fdb\u4e86\u80c3\u548c\u80a0\u9053\u7684\u53cc\u91cd\u5438\u6536\uff0c\u5e76\u964d\u4f4e\u4e86\u53d7\u8bd5\u52a8\u7269\u81ea\u8eab\u53ca\u53d7\u8bd5\u52a8\u7269\u95f4\u7684\u5dee\u5f02\uff0c\u800c\u6211\u4eec\u72ec\u7279\u7684\u590d\u65b9\u7ec4\u5408\u8fdb\u4e00\u6b65\u63d0\u5347\u4e86\u8fd9\u4e24\u9879\u6307\u6807\u3002\u6211\u4eec\u671f\u5f85\u5728\u5e74\u5e95\u524d\u83b7\u5f97ASC36o\uff08\u7247\uff09\u7684\u9876\u7ebf\u4eba\u4f53PK\u6570\u636e\uff0c\u4ee5\u53ca\u4e3a\u6211\u4eec\u7684\u53e6\u5916\u56db\u6b3e\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u9879\u76ee\u9012\u4ea4\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\uff08IND\uff09\u7533\u8bf7\u3002&#8221;<\/p>\n<p class=\"prntaj\">\u5173\u4e8ePOTENT<\/p>\n<p class=\"prntaj\">\u53e3\u670d\u591a\u80bd\u9012\u9001\u589e\u5f3a\u6280\u672f\uff08Peptide Oral Transport ENhancement Technology\uff0cPOTENT\uff09\u662f\u6b4c\u793c\u4e13\u6709\u7684\u53e3\u670d\u591a\u80bd\u9012\u9001\u5e73\u53f0\u3002\u8be5\u6280\u672f\u65e8\u5728\u63d0\u9ad8\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u5e76\u964d\u4f4e\u53d7\u8bd5\u8005\u81ea\u8eab\u53ca\u53d7\u8bd5\u8005\u95f4\u7684PK\u5dee\u5f02\uff0c\u4ece\u800c\u5b9e\u73b0\u591a\u80bd\u836f\u7269\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u7ed9\u836f\u3002\u5728\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u548c\u72ac\u4e2d\uff0cPOTENT\u63d0\u9ad8\u4e86\u591a\u80bd\u5728\u80c3\u90e8\u548c\u80a0\u9053\u90e8\u4f4d\u7684\u5438\u6536\u3002<\/p>\n<p class=\"prntaj\">\u5173\u4e8e\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>\n<p class=\"prntaj\">\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8\u662f\u4e00\u5bb6\u5168\u4ef7\u503c\u94fe\u6574\u5408\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u805a\u7126\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u4ee3\u8c22\u75be\u75c5\u540c\u7c7b\u6700\u4f73\uff08best-in-class\uff09\u548c\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u3002\u5229\u7528\u516c\u53f8\u4e13\u6709\u7684\u57fa\u4e8e\u7ed3\u6784\u7684AI\u8f85\u52a9\u836f\u7269\u53d1\u73b0\uff08Artificial Intelligence-assisted Structure-Based Drug Discovery\uff0cAISBDD\uff09\u3001\u8d85\u957f\u6548\u836f\u7269\u5f00\u53d1\u5e73\u53f0\uff08Ultra-Long-Acting Platform\uff0cULAP\uff09\u6280\u672f\u4ee5\u53ca\u53e3\u670d\u591a\u80bd\u9012\u9001\u589e\u5f3a\u6280\u672f\uff08Peptide Oral Transport ENhancement Technology\uff0cPOTENT\uff09\uff0c\u6b4c\u793c\u5df2\u81ea\u4e3b\u7814\u53d1\u591a\u6b3e\u5c0f\u5206\u5b50\u548c\u591a\u80bd\u5019\u9009\u836f\u7269\uff0c\u5305\u62ec\u5176\u6838\u5fc3\u9879\u76eeASC30\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50GLP-1R\u6fc0\u52a8\u5242\uff0c\u7528\u4e8e\u957f\u671f\u4f53\u91cd\u7ba1\u7406\u548c\u7cd6\u5c3f\u75c5\u6cbb\u7597\uff1bASC30_48FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u4e0eASC48\uff08GIPR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC30_48_39FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u3001ASC48\uff08GIPR\u6fc0\u52a8\u5242\uff09\u4e0eASC39\uff08\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC39\uff0c\u4e00\u6b3e\u4e0eeloralintide\u7c7b\u4f3c\u3001\u5f3a\u6548\u7684\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff1bASC30_39FDC\uff0c\u4e00\u6b3e\u6bcf\u65e5\u4e00\u6b21\u53e3\u670d\u5c0f\u5206\u5b50\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\uff0c\u4e3aASC30\uff08GLP-1R\u6fc0\u52a8\u5242\uff09\u4e0eASC39\uff08\u80f0\u6dc0\u7d20\u9009\u62e9\u6027\u53d7\u4f53\u6fc0\u52a8\u5242\uff08SARA\uff09\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff1bASC36i\uff0c\u4e00\u6b3e\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff1bASC36_35i FDC\uff0c\u4e00\u6b3e\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3aASC36\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\u4e0eASC35\uff08GLP-1R\/GIPR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff0c\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff1bASC35i\uff0c\u4e00\u6b3eGLP-1R\/GIPR\u53cc\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff1bASC37i\uff0c\u4e00\u6b3eGLP-1R\/GIPR\/GCGR\u4e09\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff1bASC36_37i FDC\uff0c\u4e00\u6b3e\u56db\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3aASC36\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\u4e0eASC37\uff08GLP-1R\/GIPR\/GCGR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff0c\u4e3a\u6bcf\u6708\u4e00\u6b21\u81f3\u6bcf\u5b63\u5ea6\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff1bASC36o\uff0c\u4e00\u6b3e\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3a\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\uff1bASC36_37o FDC\uff0c\u4e00\u6b3e\u56db\u9776\u70b9\u6fc0\u52a8\u5242\u591a\u80bd\uff0c\u4e3aASC36\uff08\u80f0\u6dc0\u7d20\u53d7\u4f53\u6fc0\u52a8\u5242\uff09\u4e0eASC37\uff08GLP-1R\/GIPR\/GCGR\u6fc0\u52a8\u5242\uff09\u7684\u56fa\u5b9a\u5242\u91cf\u590d\u65b9\u5236\u5242\uff0c\u4e3a\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\uff1bASC36_35o 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class=\"prntaj\">\u8be6\u60c5\u5782\u8be2\uff1a<\/p>\n<p class=\"prntaj\">Peter Vozzo<br \/>ICR Healthcare<br \/>443-231-0505 (\u7f8e\u56fd)<br \/><a href=\"mailto:Peter.vozzo@icrhealthcare.com\" target=\"_blank\" rel=\"noopener\">Peter.vozzo@icrhealthcare.com<\/a><\/p>\n<p class=\"prntaj\">\u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8PR\u548cIR\u56e2\u961f<br \/>+86-181-0650-9129 (\u4e2d\u56fd)<br \/><a href=\"mailto:pr@ascletis.com\" target=\"_blank\" rel=\"noopener\">pr@ascletis.com<\/a><br \/><a href=\"mailto:ir@ascletis.com\" target=\"_blank\" rel=\"noopener\">ir@ascletis.com<\/a><\/p>\n<p>SOURCE \u6b4c\u793c\u5236\u836f\u6709\u9650\u516c\u53f8<\/p>","protected":false},"excerpt":{"rendered":"<p>&#8211;\u00a0 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[&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":30602,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-30601","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u6b4c\u793c\u5ba3\u5e03\u5176\u6700\u5168\u9762\u7684\u6cbb\u7597\u80a5\u80d6\u75c7\u6bcf\u5468\u4e00\u6b21\u53e3\u670d\u591a\u80bd\u7ba1\u7ebf\u83b7\u5f97\u79ef\u6781\u4e34\u5e8a\u524d\u6570\u636e - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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