{"id":30941,"date":"2026-10-25T10:45:00","date_gmt":"2026-10-25T10:45:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/esmo%e5%8f%8a%e3%80%8a%e6%96%b0%e8%8b%b1%e6%a0%bc%e5%85%b0%e5%8c%bb%e5%ad%a6%e6%9d%82%e5%bf%97%e3%80%8b%e5%90%8c%e6%ad%a5%e5%8f%91%e5%b8%83optitrop-lung06%e7%a0%94%e7%a9%b6%e7%bb%93%e6%9e%9c%ef%bc%81\/"},"modified":"2026-10-25T10:45:00","modified_gmt":"2026-10-25T10:45:00","slug":"esmo%e5%8f%8a%e3%80%8a%e6%96%b0%e8%8b%b1%e6%a0%bc%e5%85%b0%e5%8c%bb%e5%ad%a6%e6%9d%82%e5%bf%97%e3%80%8b%e5%90%8c%e6%ad%a5%e5%8f%91%e5%b8%83optitrop-lung06%e7%a0%94%e7%a9%b6%e7%bb%93%e6%9e%9c%ef%bc%81","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/esmo%e5%8f%8a%e3%80%8a%e6%96%b0%e8%8b%b1%e6%a0%bc%e5%85%b0%e5%8c%bb%e5%ad%a6%e6%9d%82%e5%bf%97%e3%80%8b%e5%90%8c%e6%ad%a5%e5%8f%91%e5%b8%83optitrop-lung06%e7%a0%94%e7%a9%b6%e7%bb%93%e6%9e%9c%ef%bc%81\/","title":{"rendered":"ESMO\u53ca\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\u540c\u6b65\u53d1\u5e03OptiTROP-Lung06\u7814\u7a76\u7ed3\u679c\uff01\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u663e\u8457\u5ef6\u957fPFS"},"content":{"rendered":"

PFS\u663e\u8457\u5ef6\u957f\uff1a\u7ecfBICR\u8bc4\u4f30\uff0c\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e51% (HR 0.49\uff1b95% CI 0.36-0.65\uff1bP<0.0001)\uff0c\u4e24\u7ec4\u4e2d\u4f4dPFS\u5206\u522b\u4e3a15.0\u4e2a\u6708(95% CI 9.9-NE)\u548c5.7\u4e2a\u6708(95% CI 5.5-7.4)\u3002\u7f13\u89e3\u66f4\u6301\u4e45\uff1a\u4e24\u7ec4\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\u5206\u522b\u4e3a13.6\u4e2a\u6708\u548c6.8\u4e2a\u6708(HR 0.47\uff1b95% CI 0.29-0.77)\u3002OS\u5448\u6539\u5584\u8d8b\u52bf\uff1a\u5728\u672c\u6b21PFS\u671f\u4e2d\u5206\u6790\u65f6\uff0cOS HR\u4e3a0.58(95% CI 0.38-0.88)\uff0c\u4e24\u7ec4\u4e2d\u4f4dOS\u5747\u672a\u8fbe\u5230\u3002<\/p>\n

\u6210\u90fd<\/span>2026\u5e7410\u670825\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u56db\u5ddd\u79d1\u4f26\u535a\u6cf0\u751f\u7269\u533b\u836f\u80a1\u4efd\u6709\u9650\u516c\u53f8(“\u79d1\u4f26\u535a\u6cf0”\u6216”\u516c\u53f8”\uff0c6990.HK)\u5ba3\u5e03\uff0c\u5728\u897f\u73ed\u7259\u9a6c\u5fb7\u91cc\u4e3e\u884c\u76842026\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a(ESMO)\u5927\u4f1a\u4e0a\uff0c\u540c\u6d4e\u5927\u5b66\u9644\u5c5e\u4e1c\u65b9\u533b\u9662\u5468\u5f69\u5b58\u6559\u6388\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u4e86\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT\uff0c\u4ea6\u79f0SKB264\/MK-2870)(\u4f73\u6cf0\u83b1\u00ae)III\u671fOptiTROP-Lung06\u7814\u7a76\u7ed3\u679c(LBA66\uff1b\u4f18\u9009\u53e3\u5934\u62a5\u544a(Proffered paper)|\u8f6c\u79fb\u6027NSCLC)\u3002<\/p>\n

\n<\/div>\n

OptiTROP-Lung06\u7814\u7a76\u6210\u679c\u4ea6\u540c\u6b65\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u7ea7\u533b\u5b66\u671f\u520a\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b(The New England Journal of Medicine\uff0c\u5f71\u54cd\u56e0\u5b50=84.5)\u3002<\/p>\n

\u671f\u4e2d\u5206\u6790\u663e\u793a\uff0c\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u9ed8\u6c99\u4e1c[1]\u7684\u6297\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u86cb\u767d1(PD-1)\u5355\u6297\u5e15\u535a\u5229\u73e0\u5355\u6297(\u53ef\u745e\u8fbe\u00ae[2])\u8f83\u542b\u94c2\u53cc\u836f\u5316\u7597\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u76f8\u6bd4\u663e\u8457\u6539\u5584\u4e86\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u914d\u4f531(PD-L1)\u80bf\u7624\u6bd4\u4f8b\u5206\u6570(TPS)\uff1c1%\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53(EGFR)\u57fa\u56e0\u7a81\u53d8\u9634\u6027\u548c\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176(ALK)\u9634\u6027\u7684\u665a\u671f\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c(NSCLC)\u60a3\u8005\u4e00\u7ebf\u6cbb\u7597\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f(PFS)\uff0c\u603b\u751f\u5b58\u671f(OS)\u65b9\u9762\u4ea6\u89c2\u5bdf\u5230\u83b7\u76ca\u8d8b\u52bf\u3002<\/p>\n

\u7ecfBICR\u8bc4\u4f30\uff0c\u4e24\u7ec4\u5ba2\u89c2\u7f13\u89e3\u7387\u5206\u522b\u4e3a50.2%\u548c47.3%\uff1b\u6df1\u5ea6\u7f13\u89e3\u7387\u5206\u522b\u4e3a28.8%\u548c17.3%\u3002\u6df1\u5ea6\u7f13\u89e3\u5b9a\u4e49\u4e3a\u8fbe\u5230\u5b8c\u5168\u6216\u90e8\u5206\u7f13\u89e3\uff0c\u4e14\u9776\u75c5\u7076\u76f4\u5f84\u603b\u548c\u8f83\u57fa\u7ebf\u7f29\u5c0f\u81f3\u5c1150%\u3002<\/p>\n

\u5b89\u5168\u6027\u65b9\u9762\uff0c\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u7684\u5b89\u5168\u6027\u7279\u5f81\u4e0e\u5404\u5355\u836f\u5df2\u77e5\u7684\u5b89\u5168\u6027\u7279\u5f81\u603b\u4f53\u4e00\u81f4\uff0c\u672a\u89c2\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002\u4e0e\u542b\u94c2\u53cc\u836f\u5316\u7597\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u7ec4\u76f8\u6bd4\uff0c\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u6cbb\u7597\u7ec4\u22653\u7ea7\u6cbb\u7597\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u4e8b\u4ef6(TEAE)\u53d1\u751f\u7387\u8f83\u4f4e\uff1b\u5bfc\u81f4\u5242\u91cf\u964d\u4f4e\u6216\u6c38\u4e45\u505c\u836f\u7684TEAE\u53d1\u751f\u7387\u4e5f\u8f83\u4f4e\u3002\u4e24\u7ec4\u95f4\u8d28\u6027\u80ba\u75c5\/\u80ba\u708e\u53d1\u751f\u7387\u76f8\u4f3c\u3002<\/p>\n

\u540c\u6d4e\u5927\u5b66\u9644\u5c5e\u4e1c\u65b9\u533b\u9662\u5468\u5f69\u5b58\u6559\u6388\u8868\u793a\uff1a”\u968f\u7740OptiTROP-Lung06\u7814\u7a76\u7ed3\u679c\u7684\u8bfb\u51fa\uff0c\u6211\u4eec\u8fdb\u4e00\u6b65\u770b\u5230\u4e86\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u65b9\u6848\u5728PD-L1\u9634\u6027\u3001EGFR\/ALK\u9634\u6027\u665a\u671f\u975e\u9cde\u72b6NSCLC\u4e00\u7ebf\u6cbb\u7597\u4e2d\u7684\u4e34\u5e8a\u4ef7\u503c\u3002\u7ed3\u5408\u6b64\u524d2026\u5e74ASCO\u5927\u4f1a\u516c\u5e03\u7684OptiTROP-Lung05\u7814\u7a76\u6210\u679c\uff0c\u8be5\u8054\u5408\u65b9\u6848\u5728\u4e0d\u540cPD-L1\u8868\u8fbe\u72b6\u6001\u7684\u65e0\u9a71\u52a8\u57fa\u56e0NSCLC\u60a3\u8005\u4e2d\u5747\u663e\u793a\u51faPFS\u83b7\u76ca\uff0c\u4e3a\u5176\u4e00\u7ebf\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684III\u671f\u7814\u7a76\u8bc1\u636e\u3002”<\/p>\n

OptiTROP-Lung06\u7814\u7a76<\/p>\n

OptiTROP-Lung06(NCT06711900)\u662f\u4e00\u9879\u968f\u673a\u3001\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7eIII\u671f\u7814\u7a76\uff0c\u5171\u7eb3\u5165455\u4f8b\u60a3\u8005\uff0c\u63091:1\u6bd4\u4f8b\u968f\u673a\u63a5\u53d7\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u6216\u542b\u94c2\u53cc\u836f\u5316\u7597(\u57f9\u7f8e\u66f2\u585e\u8054\u5408\u987a\u94c2\u6216\u5361\u94c2)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u6cbb\u7597\u3002\u4e3b\u8981\u7ec8\u70b9\u4e3aBICR\u8bc4\u4f30\u7684PFS\uff0c\u6b21\u8981\u7ec8\u70b9\u5305\u62ecOS\u7b49\u3002\u622a\u81f3\u6570\u636e\u622a\u6b62\u65e5\u671f(2026\u5e746\u67089\u65e5)\uff0c\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f4\u4e3a9.7\u4e2a\u6708\u3002\u8fd9\u662f\u5168\u7403\u9996\u4e2aADC\u8054\u5408\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5728\u4e00\u7ebf\u6cbb\u7597\u9a71\u52a8\u57fa\u56e0\u9634\u6027\u3001PD-L1\u9634\u6027\u975e\u9cde\u72b6NSCLC\u4e0a\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n

\n

[1] \u9ed8\u6c99\u4e1c\u662f\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u7f57\u5a01\u5e02\u9ed8\u514b\u516c\u53f8\u7684\u5546\u53f7<\/span><\/p>\n

[2]\u00a0\u53ef\u745e\u8fbe\u00ae(\u5e15\u535a\u5229\u73e0\u5355\u6297)\u4e3a\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u7f57\u5a01\u5e02\u9ed8\u514b\u516c\u53f8\u7684\u9644\u5c5e\u516c\u53f8Merck Sharp & Dohme LLC (\u9ed8\u6c99\u4e1c)\u7684\u6ce8\u518c\u5546\u6807<\/span><\/p>\n<\/div>\n

\u5173\u4e8e\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)(\u4f73\u6cf0\u83b1\u00ae)<\/p>\n

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[…]<\/p>\n","protected":false},"author":0,"featured_media":30942,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-30941","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\nESMO\u53ca\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\u540c\u6b65\u53d1\u5e03OptiTROP-Lung06\u7814\u7a76\u7ed3\u679c\uff01\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u663e\u8457\u5ef6\u957fPFS - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/esmo\u53ca\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\u540c\u6b65\u53d1\u5e03optitrop-lung06\u7814\u7a76\u7ed3\u679c\uff01\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ESMO\u53ca\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\u540c\u6b65\u53d1\u5e03OptiTROP-Lung06\u7814\u7a76\u7ed3\u679c\uff01\u82a6\u5eb7\u6c99\u59a5\u73e0\u5355\u6297(sac-TMT)\u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u663e\u8457\u5ef6\u957fPFS - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"PFS\u663e\u8457\u5ef6\u957f\uff1a\u7ecfBICR\u8bc4\u4f30\uff0c\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e51% (HR 0.49\uff1b95% CI 0.36-0.65\uff1bP<0.0001)\uff0c\u4e24\u7ec4\u4e2d\u4f4dPFS\u5206\u522b\u4e3a15.0\u4e2a\u6708(95% CI 9.9-NE)\u548c5.7\u4e2a\u6708(95% CI 5.5-7.4)\u3002\u7f13\u89e3\u66f4\u6301\u4e45\uff1a\u4e24\u7ec4\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\u5206\u522b\u4e3a13.6\u4e2a\u6708\u548c6.8\u4e2a\u6708(HR 0.47\uff1b95% CI 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OptiTROP-Lung06\u7814\u7a76\u6210\u679c\u4ea6\u540c\u6b65\u53d1\u8868\u4e8e\u56fd\u9645\u9876\u7ea7\u533b\u5b66\u671f\u520a\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b(The New England Journal of Medicine\uff0c\u5f71\u54cd\u56e0\u5b50=84.5)\u3002 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