{"id":32090,"date":"2026-11-08T13:17:00","date_gmt":"2026-11-08T13:17:00","guid":{"rendered":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/"},"modified":"2026-11-08T13:17:00","modified_gmt":"2026-11-08T13:17:00","slug":"%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d","status":"publish","type":"post","link":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/","title":{"rendered":"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c"},"content":{"rendered":"<p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2026\u5e7411\u67088\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u56fd\u9645\u8fdb\u53e3\u535a\u89c8\u4f1a\u671f\u95f4\uff0c\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\u5409\u5229\u5fb7\u5c55\u793a\u4e86\u5176\u5728\u809d\u75c5\u9886\u57df\u7684\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\uff0c\u5176\u4e2d\u5305\u62ec\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u6cbb\u7597\u65b0\u836f\u53f8\u62c9\u5fb7\u5e15\uff08Seladelpar\uff09\uff0c\u6162\u6027\u4e59\u578b\u809d\u708e\u4e00\u7ebf\u6cbb\u7597\u836f\u7269\u97e6\u7acb\u5f97\u00ae\u548c\u6cdb\u57fa\u56e0\u578b\u4e19\u578b\u809d\u708e\u6cbb\u7597\u836f\u7269\u4e19\u901a\u6c99\u00ae\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u643a\u624b\u653f\u5e9c\u3001\u533b\u7597\u673a\u6784\u3001\u60a3\u8005\u7ec4\u7ec7\u7b49\u591a\u65b9\u4f19\u4f34\uff0c\u5f00\u5c55\u4e86\u4e00\u7cfb\u5217\u805a\u7126\u809d\u75c5\u9886\u57df\u7684\u6d3b\u52a8\uff0c\u96c6\u4e2d\u5c55\u73b0\u4e86\u8fc7\u53bb\u4e00\u5e74\u591a\u65b9\u643a\u624b\u63a8\u52a8\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u3001\u4fc3\u8fdb\u89c4\u8303\u8bca\u7597\u5b9e\u8df5\u7684\u8bf8\u591a\u6210\u679c\uff0c\u8868\u8fbe\u4e86\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u6301\u7eed\u6df1\u8015\u809d\u75c5\u9886\u57df\u7684\u957f\u671f\u627f\u8bfa\u3002<\/p>\n<p>\u5409\u5229\u5fb7\u79d1\u5b66\u5168\u7403\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u533a\u603b\u7ecf\u7406\u91d1\u65b9\u5343\u8868\u793a\uff1a&#8221;\u8fde\u7eed\u4e94\u5e74\u53c2\u5c55\u8fdb\u535a\uff0c\u5409\u5229\u5fb7\u5df2\u6709\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\u4ece\u5c55\u54c1\u8d70\u5411\u4e34\u5e8a\uff0c\u66f4\u591a\u7684\u5408\u4f5c\u9879\u76ee\u4ece\u7b7e\u7ea6\u8d70\u5411\u843d\u5730\u3002\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5PBC\uff0c\u6211\u4eec\u671f\u5f85\u643a\u624b\u793e\u4f1a\u5404\u65b9\u529b\u91cf\uff0c\u63d0\u5347\u75be\u75c5\u8ba4\u77e5\u3001\u63a8\u52a8\u89c4\u8303\u8bca\u7597\u3001\u4fc3\u8fdb\u521b\u65b0\u836f\u7269\u53ef\u53ca\uff0c\u8ba9\u60a3\u8005\u771f\u6b63\u4ece\u533b\u5b66\u8fdb\u6b65\u4e2d\u83b7\u76ca\uff0c\u52a9\u529b\u5b9e\u73b02030\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\uff0c\u5e2e\u52a9\u66f4\u591aPBC\u60a3\u8005\u8ffd\u6c42\u66f4\u9ad8\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u4e3a\u6240\u6709\u4eba\u521b\u9020\u4e00\u4e2a\u66f4\u5065\u5eb7\u7684\u4e16\u754c\u3002&#8221;<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u4ece\u8fdb\u535a\u9996\u5c55\u5230\u83b7\u6279\u5728\u671b\uff0c\u7f55\u89c1\u809d\u75c5\u521b\u65b0\u7597\u6cd5\u52a0\u901f\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005<\/p>\n<p>\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u662f\u4e00\u79cd\u6162\u6027\u81ea\u8eab\u514d\u75ab\u6027\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\uff0c\u597d\u53d1\u4e8e\u4e2d\u8001\u5e74\u5973\u6027\uff0c\u5e38\u4f34\u6709\u6301\u7eed\u6027\u7619\u75d2\u3001\u4e4f\u529b\u7b49\u75c7\u72b6\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u82e5\u5f97\u4e0d\u5230\u53ca\u65f6\u6709\u6548\u7684\u6cbb\u7597\uff0c\u75c5\u60c5\u5f88\u53ef\u80fd\u8fdb\u5c55\u4e3a\u809d\u786c\u5316\u751a\u81f3\u809d\u8870\u7aed\u30022023\u5e74\uff0cPBC\u88ab\u7eb3\u5165\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u7b49\u516d\u90e8\u95e8\u8054\u5408\u53d1\u5e03\u7684\u300a\u7b2c\u4e8c\u6279\u7f55\u89c1\u75c5\u76ee\u5f55\u300b\uff0c\u5176\u75be\u75c5\u8ba4\u77e5\u3001\u89c4\u8303\u8bca\u7597\u548c\u60a3\u8005\u5065\u5eb7\u6743\u76ca\u8fdb\u4e00\u6b65\u53d7\u5230\u5173\u6ce8\u3002<\/p>\n<p>\u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u5409\u5229\u5fb7\u4e3e\u529e\u4e86\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u521b\u65b0\u7597\u6cd5Seladelpar\u4e0a\u5e02\u524d\u4fe1\u606f\u53d1\u5e03\u4f1a\u3002\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9886\u5bfc\u3001PBC\u9886\u57df\u4e34\u5e8a\u4e13\u5bb6\u53ca\u60a3\u8005\u4ee3\u8868\u9f50\u805a\u5c55\u53f0\uff0c\u5171\u540c\u56de\u987e\u4e86Seladelpar\u4f9d\u6258&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u52a0\u901f\u60e0\u53ca\u56fd\u5185PBC\u60a3\u8005\u7684\u91cd\u8981\u8fdb\u5c55\uff0c\u5e76\u56f4\u7ed5PBC\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\u4ee5\u53ca\u672a\u6765\u591a\u65b9\u5408\u4f5c\u7684\u65b9\u5411\u548c\u673a\u4f1a\u5c55\u5f00\u63a2\u8ba8\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>Seladelpar\u662f\u4e00\u79cd\u5168\u7403\u540c\u7c7b\u9996\u521b\u3001\u53e3\u670d\u3001\u5f3a\u6548\u7684\u9009\u62e9\u6027\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u6b96\u7269\u6fc0\u6d3b\u53d7\u4f53\u03b4\uff08PPAR\u03b4\uff09\u6fc0\u52a8\u5242\uff0c\u4e5f\u662f\u5168\u7403\u9996\u4e2a\u76f8\u8f83\u4e8e\u5b89\u6170\u5242\uff0c\u5728\u751f\u5316\u5e94\u7b54\u3001\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u590d\u5e38\u548c\u7619\u75d2\u75c7\u72b6\u4e09\u4e2a\u65b9\u9762\u5747\u5c55\u73b0\u51fa\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u6539\u5584\u7684PBC\u6cbb\u7597\u836f\u7269[1]\u3002\u7ee72024\u5e74\u5728\u8fdb\u535a\u4f1a\u9996\u6b21\u5c55\u51fa\u4e4b\u540e\uff0c2025\u5e74Seladelpar\u5148\u540e\u5728\u5317\u4eac\u5929\u7afa\u7f55\u89c1\u75c5\u836f\u54c1\u4fdd\u969c\u5148\u884c\u533a\u548c\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\u3002\u5982\u4eca\uff0c\u56fd\u5185\u5df2\u6709\u591a\u540d\u6709\u9700\u8981\u7684PBC\u60a3\u8005\u7387\u5148\u4ece\u8fd9\u4e00\u521b\u65b0\u7597\u6cd5\u4e2d\u83b7\u76ca\u3002\u6b64\u5916\uff0c\u5317\u4eac\u3001\u6d77\u5357\u3001\u6d4e\u5357\u3001\u82cf\u5dde\u3001\u5357\u4eac\u7b49\u5168\u56fd\u591a\u5730\u7684\u60e0\u6c11\u4fdd\u8fd8\u5c06\u8be5\u836f\u7269\u7eb3\u5165\u5230\u6d77\u5916\u7279\u836f\u76ee\u5f55\uff0c\u51cf\u8f7b\u4e86PBC\u60a3\u8005\u4f7f\u7528\u521b\u65b0\u836f\u7269\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u5728\u4e0e\u672c\u5c4a\u8fdb\u535a\u4f1a\u540c\u671f\u53ec\u5f00\u76842026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u516c\u5e03\u4e86\u5173\u4e8eSeladelpar\u76843\u671f\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8cIDEAL\u7814\u7a76\u7684\u8be6\u7ec6\u7ed3\u679c\u3002\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u63a5\u53d7\u718a\u53bb\u6c27\u80c6\u9178\uff08UDCA\uff09\u6cbb\u759712\u4e2a\u6708\u540e\uff0cALP\u6c34\u5e73\u4ecd\u5728\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09\u76841.0\u81f31.67\u500d\u4e4b\u95f4\uff0c\u6216\u65e0\u6cd5\u8010\u53d7UDCA\u7684PBC\u6210\u4eba\u60a3\u8005\u3002\u7814\u7a76\u663e\u793a\uff0c\u5927\u90e8\u5206\u63a5\u53d7Seladelpar\u6cbb\u7597\u7684PBC\u60a3\u8005\u8fbe\u5230\u4e86\u4e3b\u8981\u590d\u5408\u7ec8\u70b9\uff0c\u5373ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff08ALP\u2264 1.0 ULN\uff09\uff0c\u4e14\u8f83\u57fa\u7ebf\u4e0b\u964d\u81f3\u5c1115%[2]\u3002\u968f\u7740PBC\u6cbb\u7597\u7406\u5ff5\u7684\u63d0\u5347\uff0c\u5c06ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff0c\u6b63\u9010\u6e10\u6210\u4e3a\u91cd\u8981\u7684\u6cbb\u7597\u76ee\u6807\u3002\u8fd9\u4e00\u6700\u65b0\u7814\u7a76\u7ed3\u679c\u4e3a\u63a2\u7d22PBC\u4e2a\u6027\u5316\u6cbb\u7597\u51b3\u7b56\uff0c\u5b9e\u73b0\u66f4\u9ad8\u7684\u6cbb\u7597\u76ee\u6807\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u65b0\u4f9d\u636e\u3002<\/p>\n<p>\u76ee\u524d\uff0cSeladelpar\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u5728\u56fd\u5bb6\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u5ba1\u8bc4\u4e2d\uff0c\u5373\u5c06\u5b9e\u73b0&#8221;\u4ece\u8fdb\u535a\u5c55\u51fa\uff0c\u5230\u5148\u884c\u5148\u8bd5\uff0c\u518d\u5230\u6b63\u5f0f\u83b7\u6279&#8221;\u7684\u91cc\u7a0b\u7891\u5f0f\u8de8\u8d8a\u3002<\/p>\n<p>\u63a8\u52a8\u4e59\u809d\u6307\u5357\u5b9e\u8df5\uff0c\u52a9\u529b\u4e19\u809d\u7279\u6b8a\u4eba\u7fa4\u7528\u836f\uff0c\u591a\u65b9\u643a\u624b\u52a0\u901f\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e<\/p>\n<p>\u591a\u5e74\u6765\uff0c\u6211\u56fd\u575a\u5b9a\u4e0d\u79fb\u5730\u63a8\u8fdb&#8221;\u9884\u9632\u4e3a\u4e3b\u3001\u9632\u6cbb\u7ed3\u5408&#8221;\u7684\u7efc\u5408\u9632\u63a7\u7b56\u7565\uff0c\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\uff08\u7b80\u79f0\u6162\u4e59\u809d\uff09\u9632\u6cbb\u65b9\u9762\u53d6\u5f97\u4e86\u663e\u8457\u6210\u6548\uff0c\u4f46\u7531\u4e8e\u60a3\u8005\u57fa\u6570\u5927\uff0c\u8bb8\u591a\u60a3\u8005\u5c1a\u672a\u88ab\u53d1\u73b0\uff0c\u6216\u53d1\u73b0\u540e\u4ecd\u672a\u80fd\u53ca\u65f6\u63a5\u53d7\u89c4\u8303\u8bca\u7597\u3002\u968f\u7740\u6162\u4e59\u809d\u6269\u5927\u6cbb\u7597\u7406\u5ff5\u7684\u63a8\u884c\uff0c\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u9879\u76ee\u5e94\u8fd0\u800c\u751f\uff0c\u6301\u7eed\u63a8\u52a8\u533b\u751f\u5b66\u672f\u4ea4\u6d41\u548c\u8bca\u7597\u80fd\u529b\u63d0\u5347\uff0c\u4fc3\u8fdb\u5148\u8fdb\u6cbb\u7597\u7406\u5ff5\u5411\u4e34\u5e8a\u5b9e\u8df5\u8f6c\u5316\uff0c\u5e76\u5e2e\u52a9\u66f4\u591a\u6162\u4e59\u809d\u60a3\u8005\u5c3d\u65e9\u63a5\u53d7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u6cbb\u7597\u3002<\/p>\n<p>\u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\u7684\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u65b0\u8fdb\u5c55\u5206\u4eab\u4f1a\u4e0a\uff0c\u5317\u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u5f90\u4eac\u676d\u6559\u6388\u5c55\u793a\u4e86\u8be5\u9879\u76ee\u57282026\u5e74\u53d6\u5f97\u7684\u9636\u6bb5\u6027\u6210\u679c\u3002\u81ea2024\u5e74\u542f\u52a8\u4ee5\u6765\uff0c\u9879\u76ee\u4e0d\u65ad\u62d3\u5c55\u548c\u6df1\u5316\u30022026\u5e74\uff0c\u8be5\u9879\u76ee\u56f4\u7ed5\u300a\u4e2d\u56fd\u9632\u6cbb\u75c5\u6bd2\u6027\u809d\u708e\u884c\u52a8\u8ba1\u5212\uff082025\u20142030\u5e74\uff09\u300b\u548c\u300a\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u8005\u533b\u7597\u673a\u6784\u5185\u7ba1\u7406\u6d41\u7a0b\u4e13\u5bb6\u5171\u8bc6\u300b\u5f00\u5c55\u5e7f\u6cdb\u5b66\u672f\u4ea4\u6d41\u7684\u540c\u65f6\uff0c\u79ef\u6781\u63a8\u52a8\u533b\u9662\u4ee5\u809d\u75c5\u3001\u611f\u67d3\u7b49\u4e13\u79d1\u79d1\u5ba4\u4e3a\u4e2d\u5fc3\uff0c\u8054\u52a8\u804c\u80fd\u79d1\u5ba4\u3001\u975e\u4e13\u79d1\u4e34\u5e8a\u79d1\u5ba4\u53ca\u5176\u4ed6\u76f8\u5173\u79d1\u5ba4\uff0c\u63a2\u7d22\u9662\u5185\u4e59\u809d\u60a3\u8005\u68c0\u6d4b\u3001\u8f6c\u8bca\u3001\u6cbb\u7597\u4e0e\u968f\u8bbf\u7684\u95ed\u73af\u7ba1\u7406\uff1b\u540c\u65f6\u652f\u6301\u897f\u90e8\u5730\u533a\u4e34\u5e8a\u80fd\u529b\u548c\u5b66\u79d1\u5efa\u8bbe\uff0c\u52a9\u529b\u6162\u4e59\u809d\u533a\u57df\u8bca\u7597\u80fd\u529b\u5747\u8861\u53d1\u5c55\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u8be5\u9879\u76ee\u5df2\u8986\u76d6\u56fd\u518564\u5bb6\u91cd\u70b9\u533b\u9662\uff0c\u672a\u6765\u8fd8\u5c06\u7ee7\u7eed\u6269\u5927\u8986\u76d6\u8303\u56f4\uff0c\u5e76\u9010\u6b65\u63a2\u7d22\u533b\u9662\u4e0e\u75be\u63a7\u3001\u793e\u533a\u7b49\u9662\u5916\u4f53\u7cfb\u7684\u8054\u52a8\uff0c\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u9662\u5185\u5916\u9632\u6cbb\u8854\u63a5\uff0c\u4e3a\u63d0\u5347\u6162\u4e59\u809d\u8bca\u7597\u6c34\u5e73\u3001\u63a8\u52a8\u6211\u56fd\u5b9e\u73b0\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\u8d21\u732e\u529b\u91cf\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u4e19\u578b\u809d\u708e\uff08\u7b80\u79f0\u4e19\u809d\uff09\u76ee\u524d\u53ef\u901a\u8fc7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\u3002\u4f46\u5728\u8fc7\u53bb\u5f88\u957f\u4e00\u6bb5\u65f6\u95f4\uff0c\u6211\u56fd\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u53ef\u9009\u62e9\u7684\u6cbb\u7597\u65b9\u6848\u6781\u4e3a\u6709\u9650\u3002\u5982\u679c\u672a\u80fd\u83b7\u5f97\u53ca\u65f6\u8bca\u7597\uff0c\u4e19\u809d\u60a3\u513f\u4e0d\u4ec5\u53ef\u80fd\u9762\u4e34\u75be\u75c5\u6301\u7eed\u8fdb\u5c55\u7684\u98ce\u9669\uff0c\u75be\u75c5\u4e5f\u53ef\u80fd\u7ed9\u5176\u6210\u957f\u548c\u5fc3\u7406\u5065\u5eb7\u5e26\u6765\u957f\u671f\u5f71\u54cd\u30022025\u5e742\u6708\uff0c\u5728&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u653f\u7b56\u652f\u6301\u4e0b\uff0c\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\uff0c\u586b\u8865\u4e86\u6211\u56fd3\u81f312\u5c81\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u6cdb\u57fa\u56e0\u578b\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u7528\u836f\u7a7a\u767d\u3002<\/p>\n<p>\u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u4e2d\u56fd\u4e19\u809d\u60a3\u513f\u6cbb\u7597\u65b0\u5e0c\u671b\u6210\u679c\u5c55\u793a\u4f1a\u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\uff0c\u6811\u5170\uff08\u535a\u9ccc\uff09\u533b\u9662\u6881\u5fd7\u519b\u6559\u6388\u5206\u4eab\u4e86\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u843d\u5730\u4e00\u5e74\u591a\u6765\u7684\u5b9e\u8df5\u8fdb\u5c55\u3002\u622a\u81f3\u76ee\u524d\uff0c\u5df2\u6709\u591a\u540d\u4e19\u809d\u60a3\u513f\u901a\u8fc7\u8be5\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\uff0c\u62e5\u62b1\u5065\u5eb7\u7ae5\u5e74\u3002\u4eca\u5e7410\u6708\uff0c\u6881\u5fd7\u519b\u6559\u6388\u53ca\u5176\u56e2\u961f\u53d1\u8868\u4e86\u300a\u7d22\u78f7\u5e03\u97e6\/\u7ef4\u5e15\u4ed6\u97e6\uff08SOF\/VEL\uff09\u9897\u7c92\u5242\u6cbb\u7597\u513f\u7ae5\u6162\u6027\u4e19\u578b\u809d\u708e\u7684\u521d\u6b65\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff1a\u6d77\u5357\u535a\u9ccc\u5148\u884c\u5148\u8bd5\u533a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u300b\uff0c\u5c06\u5148\u884c\u5148\u8bd5\u79ef\u7d2f\u7684\u5b9d\u8d35\u4e34\u5e8a\u5b9e\u8df5\u8fdb\u4e00\u6b65\u8f6c\u5316\u4e3a\u53ef\u4f9b\u66f4\u591a\u4e34\u5e8a\u533b\u751f\u53c2\u8003\u7684\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u3002\u7814\u7a76\u663e\u793a\uff0c\u5728\u5b8c\u6210\u968f\u8bbf\u768413\u4f8b\u60a3\u513f\u4e2d\uff0c\u6cbb\u7597\u7ed3\u675f\u540e12\u5468\u6301\u7eed\u75c5\u6bd2\u5b66\u5e94\u7b54\u7387\u8fbe100%\uff0c\u672a\u89c2\u5bdf\u5230\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4e5f\u672a\u53d1\u751f\u56e0\u4e0d\u826f\u4e8b\u4ef6\u5bfc\u81f4\u7684\u505c\u836f\u6216\u6cbb\u7597\u4e2d\u65ad[3]\u3002\u8fd9\u4e5f\u662f\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u4e2d\u56fd\u60a3\u513f\u4e2d\u5e94\u7528\u7684\u9996\u7bc7\u771f\u5b9e\u4e16\u754c\u6570\u636e\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u7b5b\u67e5\u662f\u63a8\u52a8\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u7684\u91cd\u8981\u4e00\u73af\u3002\u672c\u5c4a\u8fdb\u535a\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u4e0e\u91d1\u57df\u533b\u5b66\u518d\u6b21\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\uff0c\u53cc\u65b9\u5c06\u7ee7\u7eed\u53d1\u6325\u5404\u81ea\u4e13\u957f\u548c\u8d44\u6e90\u4f18\u52bf\uff0c\u5e2e\u52a9\u516c\u4f17\u63d0\u5347\u4e3b\u52a8\u7b5b\u67e5\u610f\u8bc6\uff0c\u4e86\u89e3\u81ea\u8eab\u5065\u5eb7\u72b6\u51b5\uff0c\u5e76\u63a8\u52a8\u6709\u9700\u8981\u7684\u7fa4\u4f53\u5c3d\u65e9\u83b7\u5f97\u89c4\u8303\u8bca\u7597\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u9664\u4e86\u521b\u65b0\u7597\u6cd5\u4e0e\u5408\u4f5c\u6210\u679c\uff0c\u5409\u5229\u5fb7\u5c55\u53f0\u8fd8\u5448\u73b0\u4e86\u591a\u4f4d\u771f\u5b9e\u60a3\u8005\u7684\u6545\u4e8b\uff0c\u5176\u4e2d\u6709\u4ece\u89c4\u8303\u6cbb\u7597\u4e2d\u91cd\u83b7\u751f\u6d3b\u5e0c\u671b\u7684\u6162\u4e59\u809d\u60a3\u8005\uff0c\u6709\u6210\u529f\u6218\u80dc\u4e19\u809d\u7684\u513f\u7ae5\uff0c\u4e5f\u6709\u901a\u8fc7\u81ea\u8eab\u529b\u91cf\u5e2e\u52a9\u66f4\u591a\u75c5\u53cb\u7684PBC\u60a3\u8005\u3002\u8fd9\u4e9b\u6545\u4e8b\uff0c\u8ba9\u809d\u75c5\u9632\u6cbb\u7684\u610f\u4e49\u66f4\u52a0\u5177\u4f53\u53ef\u611f\uff0c\u4e5f\u8ba9\u66f4\u591a\u4eba\u770b\u5230\u75be\u75c5\u80cc\u540e\u79ef\u6781\u751f\u6d3b\u7684\u4e2a\u4f53\uff0c\u4ee5\u53ca\u79d1\u5b66\u7a81\u7834\u548c\u89c4\u8303\u8bca\u7597\u4e3a\u60a3\u8005\u751f\u6d3b\u5e26\u6765\u7684\u5207\u5b9e\u6539\u53d8\u3002<\/p>\n<p>\u4ece\u5371\u5bb3\u516c\u4f17\u5065\u5eb7\u7684\u75c5\u6bd2\u6027\u809d\u708e\u5230\u9700\u8981\u66f4\u591a\u4eba\u5173\u6ce8\u7684\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u6301\u7eed\u4ee5\u79d1\u5b66\u521b\u65b0\u56de\u5e94\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\uff0c\u4ee5\u591a\u65b9\u5408\u4f5c\u63a8\u52a8\u521b\u65b0\u6210\u679c\u771f\u6b63\u60e0\u53ca\u60a3\u8005\u3002\u672a\u6765\uff0c\u5409\u5229\u5fb7\u5c06\u7ee7\u7eed\u4e0e\u793e\u4f1a\u5404\u754c\u4f19\u4f34\u643a\u624b\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u7684\u5efa\u8bbe\u8d21\u732e\u529b\u91cf\u3002<\/p>\n<p>\u5409\u5229\u5fb7\u8fdb\u535a\u4f1a\u5c55\u53f0\u4fe1\u606f\uff1a<\/p>\n<p>\u56fd\u5bb6\u4f1a\u5c55\u4e2d\u5fc3<\/p>\n<p>\u533b\u7597\u5668\u68b0\u53ca\u533b\u836f\u4fdd\u5065\u5c55\u533a1.1H<\/p>\n<p>\u5c55\u4f4d\u53f7\uff1a1.1A3-02<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">[1] Hirschfield GM, Bowlus CL, Mayo MJ, et al. A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis. N Engl J Med. 2024;390(9):783-794.<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[2] https:\/\/www.gilead.com\/news\/news-details\/2026\/positive-phase-3-ideal-study-results-further-support-livdelzis-seladelpar-impact-on-achieving-alp-normalization-goals-in-second-line-treatment-across-a-broad-population-of-people-living-with<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">[3] \u6881\u5fd7\u519b, \u7b49. \u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a\u5b66\u672f\u5e74\u4f1a\u66a8\u4e2d\u9752\u5e74\u5b66\u672f\u4f1a\u8bae, 2026. PU-289.<\/span><\/p>\n<\/div>\n<p>###<\/p>\n<p>\u5173\u4e8e\u5409\u5229\u5fb7\u79d1\u5b66<\/p>\n<p>\u5409\u5229\u5fb7\u79d1\u5b66\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u6210\u7acb\u8fd1\u56db\u5341\u5e74\u6765\uff0c\u63a2\u7d22\u5e76\u5b9e\u73b0\u4e86\u591a\u4e2a\u533b\u5b66\u4e0a\u66fe\u8ba4\u4e3a\u4e0d\u53ef\u80fd\u5b9e\u73b0\u7684\u7a81\u7834\uff0c\u65e8\u5728\u4e3a\u6240\u6709\u4eba\u521b\u9020\u4e00\u4e2a\u66f4\u5065\u5eb7\u7684\u4e16\u754c\u3002\u516c\u53f8\u81f4\u529b\u4e8e\u63a8\u52a8\u836f\u7269\u9769\u65b0\uff0c\u5728\u75c5\u6bd2\u5b66\u3001\u80bf\u7624\u5b66\u548c\u708e\u6027\u75be\u75c5\u9886\u57df\u5e2e\u52a9\u5e94\u5bf9\u53ef\u80fd\u5a01\u80c1\u751f\u547d\u7684\u75be\u75c5\u3002\u5409\u5229\u5fb7\u5728\u5168\u4e16\u754c\u8d85\u8fc735\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u8fd0\u8425\uff0c\u603b\u90e8\u4f4d\u4e8e\u7f8e\u56fd\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u798f\u65af\u7279\u5e02\u3002<\/p>\n<p>2017\u5e74\uff0c\u5409\u5229\u5fb7\u6b63\u5f0f\u5f00\u59cb\u5728\u4e2d\u56fd\u7684\u5546\u4e1a\u8fd0\u8425\uff0c\u4ece\u809d\u810f\u75be\u75c5\u3001HIV\u9632\u6cbb\uff0c\u5230\u6297\u771f\u83cc\u611f\u67d3\u548c\u80bf\u7624\u9886\u57df\uff0c\u6211\u4eec\u6301\u7eed\u5c06\u521b\u65b0\u836f\u7269\u548c\u89e3\u51b3\u65b9\u6848\u5f15\u5165\u4e2d\u56fd\uff0c\u52a9\u529b\u5b9e\u73b0&#8221;\u5065\u5eb7\u4e2d\u56fd&#8221;\u7684\u5b8f\u4f1f\u76ee\u6807\u3002\u77ed\u77ed\u51e0\u5e74\uff0c\u5df2\u6709\u5341\u4e09\u4e2a\u5409\u5229\u5fb7\u5168\u7403\u9886\u5148\u7684\u836f\u7269\u5728\u4e2d\u56fd\u83b7\u6279\uff0c\u5176\u4e2d\u516b\u4e2a\u836f\u7269\u5df2\u88ab\u5217\u5165\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\uff0c\u6ee1\u8db3\u66f4\u591a\u4eba\u7fa4\u5728\u75be\u75c5\u9884\u9632\u548c\u6cbb\u7597\u65b9\u9762\u7684\u5065\u5eb7\u9700\u6c42\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u5409\u5229\u5fb7\u6301\u7eed\u6df1\u5316\u5728\u4e2d\u56fd\u7684\u7814\u53d1\u4e0e\u521b\u65b0\u5e03\u5c40\uff0c\u79ef\u6781\u63a8\u8fdb\u672c\u571f\u7814\u53d1\u9879\u76ee\u7684\u843d\u5730\uff0c\u62d3\u5c55\u4e0e\u56fd\u5185\u751f\u7269\u533b\u836f\u4f01\u4e1a\u7684\u6388\u6743\u5408\u4f5c\uff0c\u8fdb\u4e00\u6b65\u94fe\u63a5\u4e2d\u56fd\u521b\u65b0\u529b\u91cf\u4e0e\u5168\u7403\u7814\u53d1\u4f53\u7cfb\uff0c\u63a8\u52a8\u66f4\u591a\u521b\u65b0\u6210\u679c\u670d\u52a1\u4e2d\u56fd\u53ca\u5168\u7403\u60a3\u8005\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>SOURCE \u5409\u5229\u5fb7\u79d1\u5b66<\/p>","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772026\u5e7411\u67088\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u56fd\u9645\u8fdb\u53e3\u535a\u89c8\u4f1a\u671f\u95f4\uff0c\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\u5409\u5229\u5fb7\u5c55\u793a\u4e86\u5176\u5728\u809d\u75c5\u9886\u57df\u7684\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\uff0c\u5176\u4e2d\u5305\u62ec\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u6cbb\u7597\u65b0\u836f\u53f8\u62c9\u5fb7\u5e15\uff08Seladelpar\uff09\uff0c\u6162\u6027\u4e59\u578b\u809d\u708e\u4e00\u7ebf\u6cbb\u7597\u836f\u7269\u97e6\u7acb\u5f97\u00ae\u548c\u6cdb\u57fa\u56e0\u578b\u4e19\u578b\u809d\u708e\u6cbb\u7597\u836f\u7269\u4e19\u901a\u6c99\u00ae\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u643a\u624b\u653f\u5e9c\u3001\u533b\u7597\u673a\u6784\u3001\u60a3\u8005\u7ec4\u7ec7\u7b49\u591a\u65b9\u4f19\u4f34\uff0c\u5f00\u5c55\u4e86\u4e00\u7cfb\u5217\u805a\u7126\u809d\u75c5\u9886\u57df\u7684\u6d3b\u52a8\uff0c\u96c6\u4e2d\u5c55\u73b0\u4e86\u8fc7\u53bb\u4e00\u5e74\u591a\u65b9\u643a\u624b\u63a8\u52a8\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u3001\u4fc3\u8fdb\u89c4\u8303\u8bca\u7597\u5b9e\u8df5\u7684\u8bf8\u591a\u6210\u679c\uff0c\u8868\u8fbe\u4e86\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u6301\u7eed\u6df1\u8015\u809d\u75c5\u9886\u57df\u7684\u957f\u671f\u627f\u8bfa\u3002 \u5409\u5229\u5fb7\u79d1\u5b66\u5168\u7403\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u533a\u603b\u7ecf\u7406\u91d1\u65b9\u5343\u8868\u793a\uff1a&#8221;\u8fde\u7eed\u4e94\u5e74\u53c2\u5c55\u8fdb\u535a\uff0c\u5409\u5229\u5fb7\u5df2\u6709\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\u4ece\u5c55\u54c1\u8d70\u5411\u4e34\u5e8a\uff0c\u66f4\u591a\u7684\u5408\u4f5c\u9879\u76ee\u4ece\u7b7e\u7ea6\u8d70\u5411\u843d\u5730\u3002\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5PBC\uff0c\u6211\u4eec\u671f\u5f85\u643a\u624b\u793e\u4f1a\u5404\u65b9\u529b\u91cf\uff0c\u63d0\u5347\u75be\u75c5\u8ba4\u77e5\u3001\u63a8\u52a8\u89c4\u8303\u8bca\u7597\u3001\u4fc3\u8fdb\u521b\u65b0\u836f\u7269\u53ef\u53ca\uff0c\u8ba9\u60a3\u8005\u771f\u6b63\u4ece\u533b\u5b66\u8fdb\u6b65\u4e2d\u83b7\u76ca\uff0c\u52a9\u529b\u5b9e\u73b02030\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\uff0c\u5e2e\u52a9\u66f4\u591aPBC\u60a3\u8005\u8ffd\u6c42\u66f4\u9ad8\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u4e3a\u6240\u6709\u4eba\u521b\u9020\u4e00\u4e2a\u66f4\u5065\u5eb7\u7684\u4e16\u754c\u3002&#8221; \u4ece\u8fdb\u535a\u9996\u5c55\u5230\u83b7\u6279\u5728\u671b\uff0c\u7f55\u89c1\u809d\u75c5\u521b\u65b0\u7597\u6cd5\u52a0\u901f\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005 \u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u662f\u4e00\u79cd\u6162\u6027\u81ea\u8eab\u514d\u75ab\u6027\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\uff0c\u597d\u53d1\u4e8e\u4e2d\u8001\u5e74\u5973\u6027\uff0c\u5e38\u4f34\u6709\u6301\u7eed\u6027\u7619\u75d2\u3001\u4e4f\u529b\u7b49\u75c7\u72b6\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u82e5\u5f97\u4e0d\u5230\u53ca\u65f6\u6709\u6548\u7684\u6cbb\u7597\uff0c\u75c5\u60c5\u5f88\u53ef\u80fd\u8fdb\u5c55\u4e3a\u809d\u786c\u5316\u751a\u81f3\u809d\u8870\u7aed\u30022023\u5e74\uff0cPBC\u88ab\u7eb3\u5165\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u7b49\u516d\u90e8\u95e8\u8054\u5408\u53d1\u5e03\u7684\u300a\u7b2c\u4e8c\u6279\u7f55\u89c1\u75c5\u76ee\u5f55\u300b\uff0c\u5176\u75be\u75c5\u8ba4\u77e5\u3001\u89c4\u8303\u8bca\u7597\u548c\u60a3\u8005\u5065\u5eb7\u6743\u76ca\u8fdb\u4e00\u6b65\u53d7\u5230\u5173\u6ce8\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u5409\u5229\u5fb7\u4e3e\u529e\u4e86\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u521b\u65b0\u7597\u6cd5Seladelpar\u4e0a\u5e02\u524d\u4fe1\u606f\u53d1\u5e03\u4f1a\u3002\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9886\u5bfc\u3001PBC\u9886\u57df\u4e34\u5e8a\u4e13\u5bb6\u53ca\u60a3\u8005\u4ee3\u8868\u9f50\u805a\u5c55\u53f0\uff0c\u5171\u540c\u56de\u987e\u4e86Seladelpar\u4f9d\u6258&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u52a0\u901f\u60e0\u53ca\u56fd\u5185PBC\u60a3\u8005\u7684\u91cd\u8981\u8fdb\u5c55\uff0c\u5e76\u56f4\u7ed5PBC\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\u4ee5\u53ca\u672a\u6765\u591a\u65b9\u5408\u4f5c\u7684\u65b9\u5411\u548c\u673a\u4f1a\u5c55\u5f00\u63a2\u8ba8\u3002 Seladelpar\u662f\u4e00\u79cd\u5168\u7403\u540c\u7c7b\u9996\u521b\u3001\u53e3\u670d\u3001\u5f3a\u6548\u7684\u9009\u62e9\u6027\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u6b96\u7269\u6fc0\u6d3b\u53d7\u4f53\u03b4\uff08PPAR\u03b4\uff09\u6fc0\u52a8\u5242\uff0c\u4e5f\u662f\u5168\u7403\u9996\u4e2a\u76f8\u8f83\u4e8e\u5b89\u6170\u5242\uff0c\u5728\u751f\u5316\u5e94\u7b54\u3001\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u590d\u5e38\u548c\u7619\u75d2\u75c7\u72b6\u4e09\u4e2a\u65b9\u9762\u5747\u5c55\u73b0\u51fa\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u6539\u5584\u7684PBC\u6cbb\u7597\u836f\u7269[1]\u3002\u7ee72024\u5e74\u5728\u8fdb\u535a\u4f1a\u9996\u6b21\u5c55\u51fa\u4e4b\u540e\uff0c2025\u5e74Seladelpar\u5148\u540e\u5728\u5317\u4eac\u5929\u7afa\u7f55\u89c1\u75c5\u836f\u54c1\u4fdd\u969c\u5148\u884c\u533a\u548c\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\u3002\u5982\u4eca\uff0c\u56fd\u5185\u5df2\u6709\u591a\u540d\u6709\u9700\u8981\u7684PBC\u60a3\u8005\u7387\u5148\u4ece\u8fd9\u4e00\u521b\u65b0\u7597\u6cd5\u4e2d\u83b7\u76ca\u3002\u6b64\u5916\uff0c\u5317\u4eac\u3001\u6d77\u5357\u3001\u6d4e\u5357\u3001\u82cf\u5dde\u3001\u5357\u4eac\u7b49\u5168\u56fd\u591a\u5730\u7684\u60e0\u6c11\u4fdd\u8fd8\u5c06\u8be5\u836f\u7269\u7eb3\u5165\u5230\u6d77\u5916\u7279\u836f\u76ee\u5f55\uff0c\u51cf\u8f7b\u4e86PBC\u60a3\u8005\u4f7f\u7528\u521b\u65b0\u836f\u7269\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002 \u5728\u4e0e\u672c\u5c4a\u8fdb\u535a\u4f1a\u540c\u671f\u53ec\u5f00\u76842026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u516c\u5e03\u4e86\u5173\u4e8eSeladelpar\u76843\u671f\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8cIDEAL\u7814\u7a76\u7684\u8be6\u7ec6\u7ed3\u679c\u3002\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u63a5\u53d7\u718a\u53bb\u6c27\u80c6\u9178\uff08UDCA\uff09\u6cbb\u759712\u4e2a\u6708\u540e\uff0cALP\u6c34\u5e73\u4ecd\u5728\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09\u76841.0\u81f31.67\u500d\u4e4b\u95f4\uff0c\u6216\u65e0\u6cd5\u8010\u53d7UDCA\u7684PBC\u6210\u4eba\u60a3\u8005\u3002\u7814\u7a76\u663e\u793a\uff0c\u5927\u90e8\u5206\u63a5\u53d7Seladelpar\u6cbb\u7597\u7684PBC\u60a3\u8005\u8fbe\u5230\u4e86\u4e3b\u8981\u590d\u5408\u7ec8\u70b9\uff0c\u5373ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff08ALP\u2264 1.0 ULN\uff09\uff0c\u4e14\u8f83\u57fa\u7ebf\u4e0b\u964d\u81f3\u5c1115%[2]\u3002\u968f\u7740PBC\u6cbb\u7597\u7406\u5ff5\u7684\u63d0\u5347\uff0c\u5c06ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff0c\u6b63\u9010\u6e10\u6210\u4e3a\u91cd\u8981\u7684\u6cbb\u7597\u76ee\u6807\u3002\u8fd9\u4e00\u6700\u65b0\u7814\u7a76\u7ed3\u679c\u4e3a\u63a2\u7d22PBC\u4e2a\u6027\u5316\u6cbb\u7597\u51b3\u7b56\uff0c\u5b9e\u73b0\u66f4\u9ad8\u7684\u6cbb\u7597\u76ee\u6807\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u65b0\u4f9d\u636e\u3002 \u76ee\u524d\uff0cSeladelpar\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u5728\u56fd\u5bb6\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u5ba1\u8bc4\u4e2d\uff0c\u5373\u5c06\u5b9e\u73b0&#8221;\u4ece\u8fdb\u535a\u5c55\u51fa\uff0c\u5230\u5148\u884c\u5148\u8bd5\uff0c\u518d\u5230\u6b63\u5f0f\u83b7\u6279&#8221;\u7684\u91cc\u7a0b\u7891\u5f0f\u8de8\u8d8a\u3002 \u63a8\u52a8\u4e59\u809d\u6307\u5357\u5b9e\u8df5\uff0c\u52a9\u529b\u4e19\u809d\u7279\u6b8a\u4eba\u7fa4\u7528\u836f\uff0c\u591a\u65b9\u643a\u624b\u52a0\u901f\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e \u591a\u5e74\u6765\uff0c\u6211\u56fd\u575a\u5b9a\u4e0d\u79fb\u5730\u63a8\u8fdb&#8221;\u9884\u9632\u4e3a\u4e3b\u3001\u9632\u6cbb\u7ed3\u5408&#8221;\u7684\u7efc\u5408\u9632\u63a7\u7b56\u7565\uff0c\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\uff08\u7b80\u79f0\u6162\u4e59\u809d\uff09\u9632\u6cbb\u65b9\u9762\u53d6\u5f97\u4e86\u663e\u8457\u6210\u6548\uff0c\u4f46\u7531\u4e8e\u60a3\u8005\u57fa\u6570\u5927\uff0c\u8bb8\u591a\u60a3\u8005\u5c1a\u672a\u88ab\u53d1\u73b0\uff0c\u6216\u53d1\u73b0\u540e\u4ecd\u672a\u80fd\u53ca\u65f6\u63a5\u53d7\u89c4\u8303\u8bca\u7597\u3002\u968f\u7740\u6162\u4e59\u809d\u6269\u5927\u6cbb\u7597\u7406\u5ff5\u7684\u63a8\u884c\uff0c\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u9879\u76ee\u5e94\u8fd0\u800c\u751f\uff0c\u6301\u7eed\u63a8\u52a8\u533b\u751f\u5b66\u672f\u4ea4\u6d41\u548c\u8bca\u7597\u80fd\u529b\u63d0\u5347\uff0c\u4fc3\u8fdb\u5148\u8fdb\u6cbb\u7597\u7406\u5ff5\u5411\u4e34\u5e8a\u5b9e\u8df5\u8f6c\u5316\uff0c\u5e76\u5e2e\u52a9\u66f4\u591a\u6162\u4e59\u809d\u60a3\u8005\u5c3d\u65e9\u63a5\u53d7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u6cbb\u7597\u3002 \u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\u7684\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u65b0\u8fdb\u5c55\u5206\u4eab\u4f1a\u4e0a\uff0c\u5317\u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u5f90\u4eac\u676d\u6559\u6388\u5c55\u793a\u4e86\u8be5\u9879\u76ee\u57282026\u5e74\u53d6\u5f97\u7684\u9636\u6bb5\u6027\u6210\u679c\u3002\u81ea2024\u5e74\u542f\u52a8\u4ee5\u6765\uff0c\u9879\u76ee\u4e0d\u65ad\u62d3\u5c55\u548c\u6df1\u5316\u30022026\u5e74\uff0c\u8be5\u9879\u76ee\u56f4\u7ed5\u300a\u4e2d\u56fd\u9632\u6cbb\u75c5\u6bd2\u6027\u809d\u708e\u884c\u52a8\u8ba1\u5212\uff082025\u20142030\u5e74\uff09\u300b\u548c\u300a\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u8005\u533b\u7597\u673a\u6784\u5185\u7ba1\u7406\u6d41\u7a0b\u4e13\u5bb6\u5171\u8bc6\u300b\u5f00\u5c55\u5e7f\u6cdb\u5b66\u672f\u4ea4\u6d41\u7684\u540c\u65f6\uff0c\u79ef\u6781\u63a8\u52a8\u533b\u9662\u4ee5\u809d\u75c5\u3001\u611f\u67d3\u7b49\u4e13\u79d1\u79d1\u5ba4\u4e3a\u4e2d\u5fc3\uff0c\u8054\u52a8\u804c\u80fd\u79d1\u5ba4\u3001\u975e\u4e13\u79d1\u4e34\u5e8a\u79d1\u5ba4\u53ca\u5176\u4ed6\u76f8\u5173\u79d1\u5ba4\uff0c\u63a2\u7d22\u9662\u5185\u4e59\u809d\u60a3\u8005\u68c0\u6d4b\u3001\u8f6c\u8bca\u3001\u6cbb\u7597\u4e0e\u968f\u8bbf\u7684\u95ed\u73af\u7ba1\u7406\uff1b\u540c\u65f6\u652f\u6301\u897f\u90e8\u5730\u533a\u4e34\u5e8a\u80fd\u529b\u548c\u5b66\u79d1\u5efa\u8bbe\uff0c\u52a9\u529b\u6162\u4e59\u809d\u533a\u57df\u8bca\u7597\u80fd\u529b\u5747\u8861\u53d1\u5c55\u3002 \u76ee\u524d\uff0c\u8be5\u9879\u76ee\u5df2\u8986\u76d6\u56fd\u518564\u5bb6\u91cd\u70b9\u533b\u9662\uff0c\u672a\u6765\u8fd8\u5c06\u7ee7\u7eed\u6269\u5927\u8986\u76d6\u8303\u56f4\uff0c\u5e76\u9010\u6b65\u63a2\u7d22\u533b\u9662\u4e0e\u75be\u63a7\u3001\u793e\u533a\u7b49\u9662\u5916\u4f53\u7cfb\u7684\u8054\u52a8\uff0c\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u9662\u5185\u5916\u9632\u6cbb\u8854\u63a5\uff0c\u4e3a\u63d0\u5347\u6162\u4e59\u809d\u8bca\u7597\u6c34\u5e73\u3001\u63a8\u52a8\u6211\u56fd\u5b9e\u73b0\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\u8d21\u732e\u529b\u91cf\u3002 \u4e19\u578b\u809d\u708e\uff08\u7b80\u79f0\u4e19\u809d\uff09\u76ee\u524d\u53ef\u901a\u8fc7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\u3002\u4f46\u5728\u8fc7\u53bb\u5f88\u957f\u4e00\u6bb5\u65f6\u95f4\uff0c\u6211\u56fd\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u53ef\u9009\u62e9\u7684\u6cbb\u7597\u65b9\u6848\u6781\u4e3a\u6709\u9650\u3002\u5982\u679c\u672a\u80fd\u83b7\u5f97\u53ca\u65f6\u8bca\u7597\uff0c\u4e19\u809d\u60a3\u513f\u4e0d\u4ec5\u53ef\u80fd\u9762\u4e34\u75be\u75c5\u6301\u7eed\u8fdb\u5c55\u7684\u98ce\u9669\uff0c\u75be\u75c5\u4e5f\u53ef\u80fd\u7ed9\u5176\u6210\u957f\u548c\u5fc3\u7406\u5065\u5eb7\u5e26\u6765\u957f\u671f\u5f71\u54cd\u30022025\u5e742\u6708\uff0c\u5728&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u653f\u7b56\u652f\u6301\u4e0b\uff0c\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\uff0c\u586b\u8865\u4e86\u6211\u56fd3\u81f312\u5c81\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u6cdb\u57fa\u56e0\u578b\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u7528\u836f\u7a7a\u767d\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u4e2d\u56fd\u4e19\u809d\u60a3\u513f\u6cbb\u7597\u65b0\u5e0c\u671b\u6210\u679c\u5c55\u793a\u4f1a\u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\uff0c\u6811\u5170\uff08\u535a\u9ccc\uff09\u533b\u9662\u6881\u5fd7\u519b\u6559\u6388\u5206\u4eab\u4e86\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u843d\u5730\u4e00\u5e74\u591a\u6765\u7684\u5b9e\u8df5\u8fdb\u5c55\u3002\u622a\u81f3\u76ee\u524d\uff0c\u5df2\u6709\u591a\u540d\u4e19\u809d\u60a3\u513f\u901a\u8fc7\u8be5\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\uff0c\u62e5\u62b1\u5065\u5eb7\u7ae5\u5e74\u3002\u4eca\u5e7410\u6708\uff0c\u6881\u5fd7\u519b\u6559\u6388\u53ca\u5176\u56e2\u961f\u53d1\u8868\u4e86\u300a\u7d22\u78f7\u5e03\u97e6\/\u7ef4\u5e15\u4ed6\u97e6\uff08SOF\/VEL\uff09\u9897\u7c92\u5242\u6cbb\u7597\u513f\u7ae5\u6162\u6027\u4e19\u578b\u809d\u708e\u7684\u521d\u6b65\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff1a\u6d77\u5357\u535a\u9ccc\u5148\u884c\u5148\u8bd5\u533a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u300b\uff0c\u5c06\u5148\u884c\u5148\u8bd5\u79ef\u7d2f\u7684\u5b9d\u8d35\u4e34\u5e8a\u5b9e\u8df5\u8fdb\u4e00\u6b65\u8f6c\u5316\u4e3a\u53ef\u4f9b\u66f4\u591a\u4e34\u5e8a\u533b\u751f\u53c2\u8003\u7684\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u3002\u7814\u7a76\u663e\u793a\uff0c\u5728\u5b8c\u6210\u968f\u8bbf\u768413\u4f8b\u60a3\u513f\u4e2d\uff0c\u6cbb\u7597\u7ed3\u675f\u540e12\u5468\u6301\u7eed\u75c5\u6bd2\u5b66\u5e94\u7b54\u7387\u8fbe100%\uff0c\u672a\u89c2\u5bdf\u5230\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4e5f\u672a\u53d1\u751f\u56e0\u4e0d\u826f\u4e8b\u4ef6\u5bfc\u81f4\u7684\u505c\u836f\u6216\u6cbb\u7597\u4e2d\u65ad[3]\u3002\u8fd9\u4e5f\u662f\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u4e2d\u56fd\u60a3\u513f\u4e2d\u5e94\u7528\u7684\u9996\u7bc7\u771f\u5b9e\u4e16\u754c\u6570\u636e\u3002 \u7b5b\u67e5\u662f\u63a8\u52a8\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u7684\u91cd\u8981\u4e00\u73af\u3002\u672c\u5c4a\u8fdb\u535a\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u4e0e\u91d1\u57df\u533b\u5b66\u518d\u6b21\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\uff0c\u53cc\u65b9\u5c06\u7ee7\u7eed\u53d1\u6325\u5404\u81ea\u4e13\u957f\u548c\u8d44\u6e90\u4f18\u52bf\uff0c\u5e2e\u52a9\u516c\u4f17\u63d0\u5347\u4e3b\u52a8\u7b5b\u67e5\u610f\u8bc6\uff0c\u4e86\u89e3\u81ea\u8eab\u5065\u5eb7\u72b6\u51b5\uff0c\u5e76\u63a8\u52a8\u6709\u9700\u8981\u7684\u7fa4\u4f53\u5c3d\u65e9\u83b7\u5f97\u89c4\u8303\u8bca\u7597\u3002 \u9664\u4e86\u521b\u65b0\u7597\u6cd5\u4e0e\u5408\u4f5c\u6210\u679c\uff0c\u5409\u5229\u5fb7\u5c55\u53f0\u8fd8\u5448\u73b0\u4e86\u591a\u4f4d\u771f\u5b9e\u60a3\u8005\u7684\u6545\u4e8b\uff0c\u5176\u4e2d\u6709\u4ece\u89c4\u8303\u6cbb\u7597\u4e2d\u91cd\u83b7\u751f\u6d3b\u5e0c\u671b\u7684\u6162\u4e59\u809d\u60a3\u8005\uff0c\u6709\u6210\u529f\u6218\u80dc\u4e19\u809d\u7684\u513f\u7ae5\uff0c\u4e5f\u6709\u901a\u8fc7\u81ea\u8eab\u529b\u91cf\u5e2e\u52a9\u66f4\u591a\u75c5\u53cb\u7684PBC\u60a3\u8005\u3002\u8fd9\u4e9b\u6545\u4e8b\uff0c\u8ba9\u809d\u75c5\u9632\u6cbb\u7684\u610f\u4e49\u66f4\u52a0\u5177\u4f53\u53ef\u611f\uff0c\u4e5f\u8ba9\u66f4\u591a\u4eba\u770b\u5230\u75be\u75c5\u80cc\u540e\u79ef\u6781\u751f\u6d3b\u7684\u4e2a\u4f53\uff0c\u4ee5\u53ca\u79d1\u5b66\u7a81\u7834\u548c\u89c4\u8303\u8bca\u7597\u4e3a\u60a3\u8005\u751f\u6d3b\u5e26\u6765\u7684\u5207\u5b9e\u6539\u53d8\u3002 \u4ece\u5371\u5bb3\u516c\u4f17\u5065\u5eb7\u7684\u75c5\u6bd2\u6027\u809d\u708e\u5230\u9700\u8981\u66f4\u591a\u4eba\u5173\u6ce8\u7684\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u6301\u7eed\u4ee5\u79d1\u5b66\u521b\u65b0\u56de\u5e94\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\uff0c\u4ee5\u591a\u65b9\u5408\u4f5c\u63a8\u52a8\u521b\u65b0\u6210\u679c\u771f\u6b63\u60e0\u53ca\u60a3\u8005\u3002\u672a\u6765\uff0c\u5409\u5229\u5fb7\u5c06\u7ee7\u7eed\u4e0e\u793e\u4f1a\u5404\u754c\u4f19\u4f34\u643a\u624b\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u7684\u5efa\u8bbe\u8d21\u732e\u529b\u91cf\u3002 \u5409\u5229\u5fb7\u8fdb\u535a\u4f1a\u5c55\u53f0\u4fe1\u606f\uff1a \u56fd\u5bb6\u4f1a\u5c55\u4e2d\u5fc3 \u533b\u7597\u5668\u68b0\u53ca\u533b\u836f\u4fdd\u5065\u5c55\u533a1.1H \u5c55\u4f4d\u53f7\uff1a1.1A3-02 [1] Hirschfield GM, Bowlus CL, Mayo MJ, et al. A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis. N Engl J Med. 2024;390(9):783-794. [2] https:\/\/www.gilead.com\/news\/news-details\/2026\/positive-phase-3-ideal-study-results-further-support-livdelzis-seladelpar-impact-on-achieving-alp-normalization-goals-in-second-line-treatment-across-a-broad-population-of-people-living-with [3] \u6881\u5fd7\u519b, \u7b49. \u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a\u5b66\u672f\u5e74\u4f1a\u66a8\u4e2d\u9752\u5e74\u5b66\u672f\u4f1a\u8bae, [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":32091,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-32090","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/moneycompass.com.my\/cn\/\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"\u4e0a\u6d772026\u5e7411\u67088\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u56fd\u9645\u8fdb\u53e3\u535a\u89c8\u4f1a\u671f\u95f4\uff0c\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\u5409\u5229\u5fb7\u5c55\u793a\u4e86\u5176\u5728\u809d\u75c5\u9886\u57df\u7684\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\uff0c\u5176\u4e2d\u5305\u62ec\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u6cbb\u7597\u65b0\u836f\u53f8\u62c9\u5fb7\u5e15\uff08Seladelpar\uff09\uff0c\u6162\u6027\u4e59\u578b\u809d\u708e\u4e00\u7ebf\u6cbb\u7597\u836f\u7269\u97e6\u7acb\u5f97\u00ae\u548c\u6cdb\u57fa\u56e0\u578b\u4e19\u578b\u809d\u708e\u6cbb\u7597\u836f\u7269\u4e19\u901a\u6c99\u00ae\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u643a\u624b\u653f\u5e9c\u3001\u533b\u7597\u673a\u6784\u3001\u60a3\u8005\u7ec4\u7ec7\u7b49\u591a\u65b9\u4f19\u4f34\uff0c\u5f00\u5c55\u4e86\u4e00\u7cfb\u5217\u805a\u7126\u809d\u75c5\u9886\u57df\u7684\u6d3b\u52a8\uff0c\u96c6\u4e2d\u5c55\u73b0\u4e86\u8fc7\u53bb\u4e00\u5e74\u591a\u65b9\u643a\u624b\u63a8\u52a8\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u3001\u4fc3\u8fdb\u89c4\u8303\u8bca\u7597\u5b9e\u8df5\u7684\u8bf8\u591a\u6210\u679c\uff0c\u8868\u8fbe\u4e86\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u6301\u7eed\u6df1\u8015\u809d\u75c5\u9886\u57df\u7684\u957f\u671f\u627f\u8bfa\u3002 \u5409\u5229\u5fb7\u79d1\u5b66\u5168\u7403\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u533a\u603b\u7ecf\u7406\u91d1\u65b9\u5343\u8868\u793a\uff1a&#8221;\u8fde\u7eed\u4e94\u5e74\u53c2\u5c55\u8fdb\u535a\uff0c\u5409\u5229\u5fb7\u5df2\u6709\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\u4ece\u5c55\u54c1\u8d70\u5411\u4e34\u5e8a\uff0c\u66f4\u591a\u7684\u5408\u4f5c\u9879\u76ee\u4ece\u7b7e\u7ea6\u8d70\u5411\u843d\u5730\u3002\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5PBC\uff0c\u6211\u4eec\u671f\u5f85\u643a\u624b\u793e\u4f1a\u5404\u65b9\u529b\u91cf\uff0c\u63d0\u5347\u75be\u75c5\u8ba4\u77e5\u3001\u63a8\u52a8\u89c4\u8303\u8bca\u7597\u3001\u4fc3\u8fdb\u521b\u65b0\u836f\u7269\u53ef\u53ca\uff0c\u8ba9\u60a3\u8005\u771f\u6b63\u4ece\u533b\u5b66\u8fdb\u6b65\u4e2d\u83b7\u76ca\uff0c\u52a9\u529b\u5b9e\u73b02030\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\uff0c\u5e2e\u52a9\u66f4\u591aPBC\u60a3\u8005\u8ffd\u6c42\u66f4\u9ad8\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u4e3a\u6240\u6709\u4eba\u521b\u9020\u4e00\u4e2a\u66f4\u5065\u5eb7\u7684\u4e16\u754c\u3002&#8221; \u4ece\u8fdb\u535a\u9996\u5c55\u5230\u83b7\u6279\u5728\u671b\uff0c\u7f55\u89c1\u809d\u75c5\u521b\u65b0\u7597\u6cd5\u52a0\u901f\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005 \u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u662f\u4e00\u79cd\u6162\u6027\u81ea\u8eab\u514d\u75ab\u6027\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\uff0c\u597d\u53d1\u4e8e\u4e2d\u8001\u5e74\u5973\u6027\uff0c\u5e38\u4f34\u6709\u6301\u7eed\u6027\u7619\u75d2\u3001\u4e4f\u529b\u7b49\u75c7\u72b6\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u82e5\u5f97\u4e0d\u5230\u53ca\u65f6\u6709\u6548\u7684\u6cbb\u7597\uff0c\u75c5\u60c5\u5f88\u53ef\u80fd\u8fdb\u5c55\u4e3a\u809d\u786c\u5316\u751a\u81f3\u809d\u8870\u7aed\u30022023\u5e74\uff0cPBC\u88ab\u7eb3\u5165\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u7b49\u516d\u90e8\u95e8\u8054\u5408\u53d1\u5e03\u7684\u300a\u7b2c\u4e8c\u6279\u7f55\u89c1\u75c5\u76ee\u5f55\u300b\uff0c\u5176\u75be\u75c5\u8ba4\u77e5\u3001\u89c4\u8303\u8bca\u7597\u548c\u60a3\u8005\u5065\u5eb7\u6743\u76ca\u8fdb\u4e00\u6b65\u53d7\u5230\u5173\u6ce8\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u5409\u5229\u5fb7\u4e3e\u529e\u4e86\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u521b\u65b0\u7597\u6cd5Seladelpar\u4e0a\u5e02\u524d\u4fe1\u606f\u53d1\u5e03\u4f1a\u3002\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9886\u5bfc\u3001PBC\u9886\u57df\u4e34\u5e8a\u4e13\u5bb6\u53ca\u60a3\u8005\u4ee3\u8868\u9f50\u805a\u5c55\u53f0\uff0c\u5171\u540c\u56de\u987e\u4e86Seladelpar\u4f9d\u6258&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u52a0\u901f\u60e0\u53ca\u56fd\u5185PBC\u60a3\u8005\u7684\u91cd\u8981\u8fdb\u5c55\uff0c\u5e76\u56f4\u7ed5PBC\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\u4ee5\u53ca\u672a\u6765\u591a\u65b9\u5408\u4f5c\u7684\u65b9\u5411\u548c\u673a\u4f1a\u5c55\u5f00\u63a2\u8ba8\u3002 Seladelpar\u662f\u4e00\u79cd\u5168\u7403\u540c\u7c7b\u9996\u521b\u3001\u53e3\u670d\u3001\u5f3a\u6548\u7684\u9009\u62e9\u6027\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u6b96\u7269\u6fc0\u6d3b\u53d7\u4f53\u03b4\uff08PPAR\u03b4\uff09\u6fc0\u52a8\u5242\uff0c\u4e5f\u662f\u5168\u7403\u9996\u4e2a\u76f8\u8f83\u4e8e\u5b89\u6170\u5242\uff0c\u5728\u751f\u5316\u5e94\u7b54\u3001\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u590d\u5e38\u548c\u7619\u75d2\u75c7\u72b6\u4e09\u4e2a\u65b9\u9762\u5747\u5c55\u73b0\u51fa\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u6539\u5584\u7684PBC\u6cbb\u7597\u836f\u7269[1]\u3002\u7ee72024\u5e74\u5728\u8fdb\u535a\u4f1a\u9996\u6b21\u5c55\u51fa\u4e4b\u540e\uff0c2025\u5e74Seladelpar\u5148\u540e\u5728\u5317\u4eac\u5929\u7afa\u7f55\u89c1\u75c5\u836f\u54c1\u4fdd\u969c\u5148\u884c\u533a\u548c\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\u3002\u5982\u4eca\uff0c\u56fd\u5185\u5df2\u6709\u591a\u540d\u6709\u9700\u8981\u7684PBC\u60a3\u8005\u7387\u5148\u4ece\u8fd9\u4e00\u521b\u65b0\u7597\u6cd5\u4e2d\u83b7\u76ca\u3002\u6b64\u5916\uff0c\u5317\u4eac\u3001\u6d77\u5357\u3001\u6d4e\u5357\u3001\u82cf\u5dde\u3001\u5357\u4eac\u7b49\u5168\u56fd\u591a\u5730\u7684\u60e0\u6c11\u4fdd\u8fd8\u5c06\u8be5\u836f\u7269\u7eb3\u5165\u5230\u6d77\u5916\u7279\u836f\u76ee\u5f55\uff0c\u51cf\u8f7b\u4e86PBC\u60a3\u8005\u4f7f\u7528\u521b\u65b0\u836f\u7269\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002 \u5728\u4e0e\u672c\u5c4a\u8fdb\u535a\u4f1a\u540c\u671f\u53ec\u5f00\u76842026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u516c\u5e03\u4e86\u5173\u4e8eSeladelpar\u76843\u671f\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8cIDEAL\u7814\u7a76\u7684\u8be6\u7ec6\u7ed3\u679c\u3002\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u63a5\u53d7\u718a\u53bb\u6c27\u80c6\u9178\uff08UDCA\uff09\u6cbb\u759712\u4e2a\u6708\u540e\uff0cALP\u6c34\u5e73\u4ecd\u5728\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09\u76841.0\u81f31.67\u500d\u4e4b\u95f4\uff0c\u6216\u65e0\u6cd5\u8010\u53d7UDCA\u7684PBC\u6210\u4eba\u60a3\u8005\u3002\u7814\u7a76\u663e\u793a\uff0c\u5927\u90e8\u5206\u63a5\u53d7Seladelpar\u6cbb\u7597\u7684PBC\u60a3\u8005\u8fbe\u5230\u4e86\u4e3b\u8981\u590d\u5408\u7ec8\u70b9\uff0c\u5373ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff08ALP\u2264 1.0 ULN\uff09\uff0c\u4e14\u8f83\u57fa\u7ebf\u4e0b\u964d\u81f3\u5c1115%[2]\u3002\u968f\u7740PBC\u6cbb\u7597\u7406\u5ff5\u7684\u63d0\u5347\uff0c\u5c06ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff0c\u6b63\u9010\u6e10\u6210\u4e3a\u91cd\u8981\u7684\u6cbb\u7597\u76ee\u6807\u3002\u8fd9\u4e00\u6700\u65b0\u7814\u7a76\u7ed3\u679c\u4e3a\u63a2\u7d22PBC\u4e2a\u6027\u5316\u6cbb\u7597\u51b3\u7b56\uff0c\u5b9e\u73b0\u66f4\u9ad8\u7684\u6cbb\u7597\u76ee\u6807\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u65b0\u4f9d\u636e\u3002 \u76ee\u524d\uff0cSeladelpar\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u5728\u56fd\u5bb6\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u5ba1\u8bc4\u4e2d\uff0c\u5373\u5c06\u5b9e\u73b0&#8221;\u4ece\u8fdb\u535a\u5c55\u51fa\uff0c\u5230\u5148\u884c\u5148\u8bd5\uff0c\u518d\u5230\u6b63\u5f0f\u83b7\u6279&#8221;\u7684\u91cc\u7a0b\u7891\u5f0f\u8de8\u8d8a\u3002 \u63a8\u52a8\u4e59\u809d\u6307\u5357\u5b9e\u8df5\uff0c\u52a9\u529b\u4e19\u809d\u7279\u6b8a\u4eba\u7fa4\u7528\u836f\uff0c\u591a\u65b9\u643a\u624b\u52a0\u901f\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e \u591a\u5e74\u6765\uff0c\u6211\u56fd\u575a\u5b9a\u4e0d\u79fb\u5730\u63a8\u8fdb&#8221;\u9884\u9632\u4e3a\u4e3b\u3001\u9632\u6cbb\u7ed3\u5408&#8221;\u7684\u7efc\u5408\u9632\u63a7\u7b56\u7565\uff0c\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\uff08\u7b80\u79f0\u6162\u4e59\u809d\uff09\u9632\u6cbb\u65b9\u9762\u53d6\u5f97\u4e86\u663e\u8457\u6210\u6548\uff0c\u4f46\u7531\u4e8e\u60a3\u8005\u57fa\u6570\u5927\uff0c\u8bb8\u591a\u60a3\u8005\u5c1a\u672a\u88ab\u53d1\u73b0\uff0c\u6216\u53d1\u73b0\u540e\u4ecd\u672a\u80fd\u53ca\u65f6\u63a5\u53d7\u89c4\u8303\u8bca\u7597\u3002\u968f\u7740\u6162\u4e59\u809d\u6269\u5927\u6cbb\u7597\u7406\u5ff5\u7684\u63a8\u884c\uff0c\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u9879\u76ee\u5e94\u8fd0\u800c\u751f\uff0c\u6301\u7eed\u63a8\u52a8\u533b\u751f\u5b66\u672f\u4ea4\u6d41\u548c\u8bca\u7597\u80fd\u529b\u63d0\u5347\uff0c\u4fc3\u8fdb\u5148\u8fdb\u6cbb\u7597\u7406\u5ff5\u5411\u4e34\u5e8a\u5b9e\u8df5\u8f6c\u5316\uff0c\u5e76\u5e2e\u52a9\u66f4\u591a\u6162\u4e59\u809d\u60a3\u8005\u5c3d\u65e9\u63a5\u53d7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u6cbb\u7597\u3002 \u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\u7684\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u65b0\u8fdb\u5c55\u5206\u4eab\u4f1a\u4e0a\uff0c\u5317\u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u5f90\u4eac\u676d\u6559\u6388\u5c55\u793a\u4e86\u8be5\u9879\u76ee\u57282026\u5e74\u53d6\u5f97\u7684\u9636\u6bb5\u6027\u6210\u679c\u3002\u81ea2024\u5e74\u542f\u52a8\u4ee5\u6765\uff0c\u9879\u76ee\u4e0d\u65ad\u62d3\u5c55\u548c\u6df1\u5316\u30022026\u5e74\uff0c\u8be5\u9879\u76ee\u56f4\u7ed5\u300a\u4e2d\u56fd\u9632\u6cbb\u75c5\u6bd2\u6027\u809d\u708e\u884c\u52a8\u8ba1\u5212\uff082025\u20142030\u5e74\uff09\u300b\u548c\u300a\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u8005\u533b\u7597\u673a\u6784\u5185\u7ba1\u7406\u6d41\u7a0b\u4e13\u5bb6\u5171\u8bc6\u300b\u5f00\u5c55\u5e7f\u6cdb\u5b66\u672f\u4ea4\u6d41\u7684\u540c\u65f6\uff0c\u79ef\u6781\u63a8\u52a8\u533b\u9662\u4ee5\u809d\u75c5\u3001\u611f\u67d3\u7b49\u4e13\u79d1\u79d1\u5ba4\u4e3a\u4e2d\u5fc3\uff0c\u8054\u52a8\u804c\u80fd\u79d1\u5ba4\u3001\u975e\u4e13\u79d1\u4e34\u5e8a\u79d1\u5ba4\u53ca\u5176\u4ed6\u76f8\u5173\u79d1\u5ba4\uff0c\u63a2\u7d22\u9662\u5185\u4e59\u809d\u60a3\u8005\u68c0\u6d4b\u3001\u8f6c\u8bca\u3001\u6cbb\u7597\u4e0e\u968f\u8bbf\u7684\u95ed\u73af\u7ba1\u7406\uff1b\u540c\u65f6\u652f\u6301\u897f\u90e8\u5730\u533a\u4e34\u5e8a\u80fd\u529b\u548c\u5b66\u79d1\u5efa\u8bbe\uff0c\u52a9\u529b\u6162\u4e59\u809d\u533a\u57df\u8bca\u7597\u80fd\u529b\u5747\u8861\u53d1\u5c55\u3002 \u76ee\u524d\uff0c\u8be5\u9879\u76ee\u5df2\u8986\u76d6\u56fd\u518564\u5bb6\u91cd\u70b9\u533b\u9662\uff0c\u672a\u6765\u8fd8\u5c06\u7ee7\u7eed\u6269\u5927\u8986\u76d6\u8303\u56f4\uff0c\u5e76\u9010\u6b65\u63a2\u7d22\u533b\u9662\u4e0e\u75be\u63a7\u3001\u793e\u533a\u7b49\u9662\u5916\u4f53\u7cfb\u7684\u8054\u52a8\uff0c\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u9662\u5185\u5916\u9632\u6cbb\u8854\u63a5\uff0c\u4e3a\u63d0\u5347\u6162\u4e59\u809d\u8bca\u7597\u6c34\u5e73\u3001\u63a8\u52a8\u6211\u56fd\u5b9e\u73b0\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\u8d21\u732e\u529b\u91cf\u3002 \u4e19\u578b\u809d\u708e\uff08\u7b80\u79f0\u4e19\u809d\uff09\u76ee\u524d\u53ef\u901a\u8fc7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\u3002\u4f46\u5728\u8fc7\u53bb\u5f88\u957f\u4e00\u6bb5\u65f6\u95f4\uff0c\u6211\u56fd\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u53ef\u9009\u62e9\u7684\u6cbb\u7597\u65b9\u6848\u6781\u4e3a\u6709\u9650\u3002\u5982\u679c\u672a\u80fd\u83b7\u5f97\u53ca\u65f6\u8bca\u7597\uff0c\u4e19\u809d\u60a3\u513f\u4e0d\u4ec5\u53ef\u80fd\u9762\u4e34\u75be\u75c5\u6301\u7eed\u8fdb\u5c55\u7684\u98ce\u9669\uff0c\u75be\u75c5\u4e5f\u53ef\u80fd\u7ed9\u5176\u6210\u957f\u548c\u5fc3\u7406\u5065\u5eb7\u5e26\u6765\u957f\u671f\u5f71\u54cd\u30022025\u5e742\u6708\uff0c\u5728&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u653f\u7b56\u652f\u6301\u4e0b\uff0c\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\uff0c\u586b\u8865\u4e86\u6211\u56fd3\u81f312\u5c81\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u6cdb\u57fa\u56e0\u578b\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u7528\u836f\u7a7a\u767d\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u4e2d\u56fd\u4e19\u809d\u60a3\u513f\u6cbb\u7597\u65b0\u5e0c\u671b\u6210\u679c\u5c55\u793a\u4f1a\u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\uff0c\u6811\u5170\uff08\u535a\u9ccc\uff09\u533b\u9662\u6881\u5fd7\u519b\u6559\u6388\u5206\u4eab\u4e86\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u843d\u5730\u4e00\u5e74\u591a\u6765\u7684\u5b9e\u8df5\u8fdb\u5c55\u3002\u622a\u81f3\u76ee\u524d\uff0c\u5df2\u6709\u591a\u540d\u4e19\u809d\u60a3\u513f\u901a\u8fc7\u8be5\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\uff0c\u62e5\u62b1\u5065\u5eb7\u7ae5\u5e74\u3002\u4eca\u5e7410\u6708\uff0c\u6881\u5fd7\u519b\u6559\u6388\u53ca\u5176\u56e2\u961f\u53d1\u8868\u4e86\u300a\u7d22\u78f7\u5e03\u97e6\/\u7ef4\u5e15\u4ed6\u97e6\uff08SOF\/VEL\uff09\u9897\u7c92\u5242\u6cbb\u7597\u513f\u7ae5\u6162\u6027\u4e19\u578b\u809d\u708e\u7684\u521d\u6b65\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff1a\u6d77\u5357\u535a\u9ccc\u5148\u884c\u5148\u8bd5\u533a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u300b\uff0c\u5c06\u5148\u884c\u5148\u8bd5\u79ef\u7d2f\u7684\u5b9d\u8d35\u4e34\u5e8a\u5b9e\u8df5\u8fdb\u4e00\u6b65\u8f6c\u5316\u4e3a\u53ef\u4f9b\u66f4\u591a\u4e34\u5e8a\u533b\u751f\u53c2\u8003\u7684\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u3002\u7814\u7a76\u663e\u793a\uff0c\u5728\u5b8c\u6210\u968f\u8bbf\u768413\u4f8b\u60a3\u513f\u4e2d\uff0c\u6cbb\u7597\u7ed3\u675f\u540e12\u5468\u6301\u7eed\u75c5\u6bd2\u5b66\u5e94\u7b54\u7387\u8fbe100%\uff0c\u672a\u89c2\u5bdf\u5230\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4e5f\u672a\u53d1\u751f\u56e0\u4e0d\u826f\u4e8b\u4ef6\u5bfc\u81f4\u7684\u505c\u836f\u6216\u6cbb\u7597\u4e2d\u65ad[3]\u3002\u8fd9\u4e5f\u662f\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u4e2d\u56fd\u60a3\u513f\u4e2d\u5e94\u7528\u7684\u9996\u7bc7\u771f\u5b9e\u4e16\u754c\u6570\u636e\u3002 \u7b5b\u67e5\u662f\u63a8\u52a8\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u7684\u91cd\u8981\u4e00\u73af\u3002\u672c\u5c4a\u8fdb\u535a\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u4e0e\u91d1\u57df\u533b\u5b66\u518d\u6b21\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\uff0c\u53cc\u65b9\u5c06\u7ee7\u7eed\u53d1\u6325\u5404\u81ea\u4e13\u957f\u548c\u8d44\u6e90\u4f18\u52bf\uff0c\u5e2e\u52a9\u516c\u4f17\u63d0\u5347\u4e3b\u52a8\u7b5b\u67e5\u610f\u8bc6\uff0c\u4e86\u89e3\u81ea\u8eab\u5065\u5eb7\u72b6\u51b5\uff0c\u5e76\u63a8\u52a8\u6709\u9700\u8981\u7684\u7fa4\u4f53\u5c3d\u65e9\u83b7\u5f97\u89c4\u8303\u8bca\u7597\u3002 \u9664\u4e86\u521b\u65b0\u7597\u6cd5\u4e0e\u5408\u4f5c\u6210\u679c\uff0c\u5409\u5229\u5fb7\u5c55\u53f0\u8fd8\u5448\u73b0\u4e86\u591a\u4f4d\u771f\u5b9e\u60a3\u8005\u7684\u6545\u4e8b\uff0c\u5176\u4e2d\u6709\u4ece\u89c4\u8303\u6cbb\u7597\u4e2d\u91cd\u83b7\u751f\u6d3b\u5e0c\u671b\u7684\u6162\u4e59\u809d\u60a3\u8005\uff0c\u6709\u6210\u529f\u6218\u80dc\u4e19\u809d\u7684\u513f\u7ae5\uff0c\u4e5f\u6709\u901a\u8fc7\u81ea\u8eab\u529b\u91cf\u5e2e\u52a9\u66f4\u591a\u75c5\u53cb\u7684PBC\u60a3\u8005\u3002\u8fd9\u4e9b\u6545\u4e8b\uff0c\u8ba9\u809d\u75c5\u9632\u6cbb\u7684\u610f\u4e49\u66f4\u52a0\u5177\u4f53\u53ef\u611f\uff0c\u4e5f\u8ba9\u66f4\u591a\u4eba\u770b\u5230\u75be\u75c5\u80cc\u540e\u79ef\u6781\u751f\u6d3b\u7684\u4e2a\u4f53\uff0c\u4ee5\u53ca\u79d1\u5b66\u7a81\u7834\u548c\u89c4\u8303\u8bca\u7597\u4e3a\u60a3\u8005\u751f\u6d3b\u5e26\u6765\u7684\u5207\u5b9e\u6539\u53d8\u3002 \u4ece\u5371\u5bb3\u516c\u4f17\u5065\u5eb7\u7684\u75c5\u6bd2\u6027\u809d\u708e\u5230\u9700\u8981\u66f4\u591a\u4eba\u5173\u6ce8\u7684\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u6301\u7eed\u4ee5\u79d1\u5b66\u521b\u65b0\u56de\u5e94\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\uff0c\u4ee5\u591a\u65b9\u5408\u4f5c\u63a8\u52a8\u521b\u65b0\u6210\u679c\u771f\u6b63\u60e0\u53ca\u60a3\u8005\u3002\u672a\u6765\uff0c\u5409\u5229\u5fb7\u5c06\u7ee7\u7eed\u4e0e\u793e\u4f1a\u5404\u754c\u4f19\u4f34\u643a\u624b\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u7684\u5efa\u8bbe\u8d21\u732e\u529b\u91cf\u3002 \u5409\u5229\u5fb7\u8fdb\u535a\u4f1a\u5c55\u53f0\u4fe1\u606f\uff1a \u56fd\u5bb6\u4f1a\u5c55\u4e2d\u5fc3 \u533b\u7597\u5668\u68b0\u53ca\u533b\u836f\u4fdd\u5065\u5c55\u533a1.1H \u5c55\u4f4d\u53f7\uff1a1.1A3-02 [1] Hirschfield GM, Bowlus CL, Mayo MJ, et al. A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis. N Engl J Med. 2024;390(9):783-794. [2] https:\/\/www.gilead.com\/news\/news-details\/2026\/positive-phase-3-ideal-study-results-further-support-livdelzis-seladelpar-impact-on-achieving-alp-normalization-goals-in-second-line-treatment-across-a-broad-population-of-people-living-with [3] \u6881\u5fd7\u519b, \u7b49. \u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a\u5b66\u672f\u5e74\u4f1a\u66a8\u4e2d\u9752\u5e74\u5b66\u672f\u4f1a\u8bae, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2026-11-08T13:17:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/\",\"name\":\"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN\",\"isPartOf\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg\",\"datePublished\":\"2026-11-08T13:17:00+00:00\",\"dateModified\":\"2026-11-08T13:17:00+00:00\",\"author\":{\"@id\":\"\"},\"breadcrumb\":{\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg\",\"contentUrl\":\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg\",\"width\":144,\"height\":96},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/moneycompass.com.my\/cn\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/moneycompass.com.my\/cn\/#website\",\"url\":\"https:\/\/moneycompass.com.my\/cn\/\",\"name\":\"Money Compass CN\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/moneycompass.com.my\/cn\/\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\/","og_locale":"en_US","og_type":"article","og_title":"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN","og_description":"\u4e0a\u6d772026\u5e7411\u67088\u65e5 \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u56fd\u9645\u8fdb\u53e3\u535a\u89c8\u4f1a\u671f\u95f4\uff0c\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\u5409\u5229\u5fb7\u5c55\u793a\u4e86\u5176\u5728\u809d\u75c5\u9886\u57df\u7684\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\uff0c\u5176\u4e2d\u5305\u62ec\u5168\u7403\u540c\u7c7b\u9996\u521b\u7684\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u6cbb\u7597\u65b0\u836f\u53f8\u62c9\u5fb7\u5e15\uff08Seladelpar\uff09\uff0c\u6162\u6027\u4e59\u578b\u809d\u708e\u4e00\u7ebf\u6cbb\u7597\u836f\u7269\u97e6\u7acb\u5f97\u00ae\u548c\u6cdb\u57fa\u56e0\u578b\u4e19\u578b\u809d\u708e\u6cbb\u7597\u836f\u7269\u4e19\u901a\u6c99\u00ae\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u643a\u624b\u653f\u5e9c\u3001\u533b\u7597\u673a\u6784\u3001\u60a3\u8005\u7ec4\u7ec7\u7b49\u591a\u65b9\u4f19\u4f34\uff0c\u5f00\u5c55\u4e86\u4e00\u7cfb\u5217\u805a\u7126\u809d\u75c5\u9886\u57df\u7684\u6d3b\u52a8\uff0c\u96c6\u4e2d\u5c55\u73b0\u4e86\u8fc7\u53bb\u4e00\u5e74\u591a\u65b9\u643a\u624b\u63a8\u52a8\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u3001\u4fc3\u8fdb\u89c4\u8303\u8bca\u7597\u5b9e\u8df5\u7684\u8bf8\u591a\u6210\u679c\uff0c\u8868\u8fbe\u4e86\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u6301\u7eed\u6df1\u8015\u809d\u75c5\u9886\u57df\u7684\u957f\u671f\u627f\u8bfa\u3002 \u5409\u5229\u5fb7\u79d1\u5b66\u5168\u7403\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u533a\u603b\u7ecf\u7406\u91d1\u65b9\u5343\u8868\u793a\uff1a&#8221;\u8fde\u7eed\u4e94\u5e74\u53c2\u5c55\u8fdb\u535a\uff0c\u5409\u5229\u5fb7\u5df2\u6709\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\u4ece\u5c55\u54c1\u8d70\u5411\u4e34\u5e8a\uff0c\u66f4\u591a\u7684\u5408\u4f5c\u9879\u76ee\u4ece\u7b7e\u7ea6\u8d70\u5411\u843d\u5730\u3002\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5PBC\uff0c\u6211\u4eec\u671f\u5f85\u643a\u624b\u793e\u4f1a\u5404\u65b9\u529b\u91cf\uff0c\u63d0\u5347\u75be\u75c5\u8ba4\u77e5\u3001\u63a8\u52a8\u89c4\u8303\u8bca\u7597\u3001\u4fc3\u8fdb\u521b\u65b0\u836f\u7269\u53ef\u53ca\uff0c\u8ba9\u60a3\u8005\u771f\u6b63\u4ece\u533b\u5b66\u8fdb\u6b65\u4e2d\u83b7\u76ca\uff0c\u52a9\u529b\u5b9e\u73b02030\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\uff0c\u5e2e\u52a9\u66f4\u591aPBC\u60a3\u8005\u8ffd\u6c42\u66f4\u9ad8\u7684\u751f\u6d3b\u8d28\u91cf\uff0c\u4e3a\u6240\u6709\u4eba\u521b\u9020\u4e00\u4e2a\u66f4\u5065\u5eb7\u7684\u4e16\u754c\u3002&#8221; \u4ece\u8fdb\u535a\u9996\u5c55\u5230\u83b7\u6279\u5728\u671b\uff0c\u7f55\u89c1\u809d\u75c5\u521b\u65b0\u7597\u6cd5\u52a0\u901f\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005 \u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff08PBC\uff09\u662f\u4e00\u79cd\u6162\u6027\u81ea\u8eab\u514d\u75ab\u6027\u80c6\u6c41\u6de4\u79ef\u6027\u809d\u75c5\uff0c\u597d\u53d1\u4e8e\u4e2d\u8001\u5e74\u5973\u6027\uff0c\u5e38\u4f34\u6709\u6301\u7eed\u6027\u7619\u75d2\u3001\u4e4f\u529b\u7b49\u75c7\u72b6\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u82e5\u5f97\u4e0d\u5230\u53ca\u65f6\u6709\u6548\u7684\u6cbb\u7597\uff0c\u75c5\u60c5\u5f88\u53ef\u80fd\u8fdb\u5c55\u4e3a\u809d\u786c\u5316\u751a\u81f3\u809d\u8870\u7aed\u30022023\u5e74\uff0cPBC\u88ab\u7eb3\u5165\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u7b49\u516d\u90e8\u95e8\u8054\u5408\u53d1\u5e03\u7684\u300a\u7b2c\u4e8c\u6279\u7f55\u89c1\u75c5\u76ee\u5f55\u300b\uff0c\u5176\u75be\u75c5\u8ba4\u77e5\u3001\u89c4\u8303\u8bca\u7597\u548c\u60a3\u8005\u5065\u5eb7\u6743\u76ca\u8fdb\u4e00\u6b65\u53d7\u5230\u5173\u6ce8\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u5409\u5229\u5fb7\u4e3e\u529e\u4e86\u539f\u53d1\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\u521b\u65b0\u7597\u6cd5Seladelpar\u4e0a\u5e02\u524d\u4fe1\u606f\u53d1\u5e03\u4f1a\u3002\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9886\u5bfc\u3001PBC\u9886\u57df\u4e34\u5e8a\u4e13\u5bb6\u53ca\u60a3\u8005\u4ee3\u8868\u9f50\u805a\u5c55\u53f0\uff0c\u5171\u540c\u56de\u987e\u4e86Seladelpar\u4f9d\u6258&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u52a0\u901f\u60e0\u53ca\u56fd\u5185PBC\u60a3\u8005\u7684\u91cd\u8981\u8fdb\u5c55\uff0c\u5e76\u56f4\u7ed5PBC\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\u4ee5\u53ca\u672a\u6765\u591a\u65b9\u5408\u4f5c\u7684\u65b9\u5411\u548c\u673a\u4f1a\u5c55\u5f00\u63a2\u8ba8\u3002 Seladelpar\u662f\u4e00\u79cd\u5168\u7403\u540c\u7c7b\u9996\u521b\u3001\u53e3\u670d\u3001\u5f3a\u6548\u7684\u9009\u62e9\u6027\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u6b96\u7269\u6fc0\u6d3b\u53d7\u4f53\u03b4\uff08PPAR\u03b4\uff09\u6fc0\u52a8\u5242\uff0c\u4e5f\u662f\u5168\u7403\u9996\u4e2a\u76f8\u8f83\u4e8e\u5b89\u6170\u5242\uff0c\u5728\u751f\u5316\u5e94\u7b54\u3001\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u590d\u5e38\u548c\u7619\u75d2\u75c7\u72b6\u4e09\u4e2a\u65b9\u9762\u5747\u5c55\u73b0\u51fa\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u6539\u5584\u7684PBC\u6cbb\u7597\u836f\u7269[1]\u3002\u7ee72024\u5e74\u5728\u8fdb\u535a\u4f1a\u9996\u6b21\u5c55\u51fa\u4e4b\u540e\uff0c2025\u5e74Seladelpar\u5148\u540e\u5728\u5317\u4eac\u5929\u7afa\u7f55\u89c1\u75c5\u836f\u54c1\u4fdd\u969c\u5148\u884c\u533a\u548c\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\u3002\u5982\u4eca\uff0c\u56fd\u5185\u5df2\u6709\u591a\u540d\u6709\u9700\u8981\u7684PBC\u60a3\u8005\u7387\u5148\u4ece\u8fd9\u4e00\u521b\u65b0\u7597\u6cd5\u4e2d\u83b7\u76ca\u3002\u6b64\u5916\uff0c\u5317\u4eac\u3001\u6d77\u5357\u3001\u6d4e\u5357\u3001\u82cf\u5dde\u3001\u5357\u4eac\u7b49\u5168\u56fd\u591a\u5730\u7684\u60e0\u6c11\u4fdd\u8fd8\u5c06\u8be5\u836f\u7269\u7eb3\u5165\u5230\u6d77\u5916\u7279\u836f\u76ee\u5f55\uff0c\u51cf\u8f7b\u4e86PBC\u60a3\u8005\u4f7f\u7528\u521b\u65b0\u836f\u7269\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002 \u5728\u4e0e\u672c\u5c4a\u8fdb\u535a\u4f1a\u540c\u671f\u53ec\u5f00\u76842026\u5e74\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u516c\u5e03\u4e86\u5173\u4e8eSeladelpar\u76843\u671f\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8cIDEAL\u7814\u7a76\u7684\u8be6\u7ec6\u7ed3\u679c\u3002\u8be5\u7814\u7a76\u7eb3\u5165\u4e86\u63a5\u53d7\u718a\u53bb\u6c27\u80c6\u9178\uff08UDCA\uff09\u6cbb\u759712\u4e2a\u6708\u540e\uff0cALP\u6c34\u5e73\u4ecd\u5728\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09\u76841.0\u81f31.67\u500d\u4e4b\u95f4\uff0c\u6216\u65e0\u6cd5\u8010\u53d7UDCA\u7684PBC\u6210\u4eba\u60a3\u8005\u3002\u7814\u7a76\u663e\u793a\uff0c\u5927\u90e8\u5206\u63a5\u53d7Seladelpar\u6cbb\u7597\u7684PBC\u60a3\u8005\u8fbe\u5230\u4e86\u4e3b\u8981\u590d\u5408\u7ec8\u70b9\uff0c\u5373ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff08ALP\u2264 1.0 ULN\uff09\uff0c\u4e14\u8f83\u57fa\u7ebf\u4e0b\u964d\u81f3\u5c1115%[2]\u3002\u968f\u7740PBC\u6cbb\u7597\u7406\u5ff5\u7684\u63d0\u5347\uff0c\u5c06ALP\u964d\u81f3\u6b63\u5e38\u8303\u56f4\uff0c\u6b63\u9010\u6e10\u6210\u4e3a\u91cd\u8981\u7684\u6cbb\u7597\u76ee\u6807\u3002\u8fd9\u4e00\u6700\u65b0\u7814\u7a76\u7ed3\u679c\u4e3a\u63a2\u7d22PBC\u4e2a\u6027\u5316\u6cbb\u7597\u51b3\u7b56\uff0c\u5b9e\u73b0\u66f4\u9ad8\u7684\u6cbb\u7597\u76ee\u6807\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u65b0\u4f9d\u636e\u3002 \u76ee\u524d\uff0cSeladelpar\u5728\u4e2d\u56fd\u7684\u4e0a\u5e02\u7533\u8bf7\u5728\u56fd\u5bb6\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u5ba1\u8bc4\u4e2d\uff0c\u5373\u5c06\u5b9e\u73b0&#8221;\u4ece\u8fdb\u535a\u5c55\u51fa\uff0c\u5230\u5148\u884c\u5148\u8bd5\uff0c\u518d\u5230\u6b63\u5f0f\u83b7\u6279&#8221;\u7684\u91cc\u7a0b\u7891\u5f0f\u8de8\u8d8a\u3002 \u63a8\u52a8\u4e59\u809d\u6307\u5357\u5b9e\u8df5\uff0c\u52a9\u529b\u4e19\u809d\u7279\u6b8a\u4eba\u7fa4\u7528\u836f\uff0c\u591a\u65b9\u643a\u624b\u52a0\u901f\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e \u591a\u5e74\u6765\uff0c\u6211\u56fd\u575a\u5b9a\u4e0d\u79fb\u5730\u63a8\u8fdb&#8221;\u9884\u9632\u4e3a\u4e3b\u3001\u9632\u6cbb\u7ed3\u5408&#8221;\u7684\u7efc\u5408\u9632\u63a7\u7b56\u7565\uff0c\u5728\u6162\u6027\u4e59\u578b\u809d\u708e\uff08\u7b80\u79f0\u6162\u4e59\u809d\uff09\u9632\u6cbb\u65b9\u9762\u53d6\u5f97\u4e86\u663e\u8457\u6210\u6548\uff0c\u4f46\u7531\u4e8e\u60a3\u8005\u57fa\u6570\u5927\uff0c\u8bb8\u591a\u60a3\u8005\u5c1a\u672a\u88ab\u53d1\u73b0\uff0c\u6216\u53d1\u73b0\u540e\u4ecd\u672a\u80fd\u53ca\u65f6\u63a5\u53d7\u89c4\u8303\u8bca\u7597\u3002\u968f\u7740\u6162\u4e59\u809d\u6269\u5927\u6cbb\u7597\u7406\u5ff5\u7684\u63a8\u884c\uff0c\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u9879\u76ee\u5e94\u8fd0\u800c\u751f\uff0c\u6301\u7eed\u63a8\u52a8\u533b\u751f\u5b66\u672f\u4ea4\u6d41\u548c\u8bca\u7597\u80fd\u529b\u63d0\u5347\uff0c\u4fc3\u8fdb\u5148\u8fdb\u6cbb\u7597\u7406\u5ff5\u5411\u4e34\u5e8a\u5b9e\u8df5\u8f6c\u5316\uff0c\u5e76\u5e2e\u52a9\u66f4\u591a\u6162\u4e59\u809d\u60a3\u8005\u5c3d\u65e9\u63a5\u53d7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u6cbb\u7597\u3002 \u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\u7684\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u6307\u5357\u5b9e\u8df5\u5de5\u7a0b\u65b0\u8fdb\u5c55\u5206\u4eab\u4f1a\u4e0a\uff0c\u5317\u4eac\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u5f90\u4eac\u676d\u6559\u6388\u5c55\u793a\u4e86\u8be5\u9879\u76ee\u57282026\u5e74\u53d6\u5f97\u7684\u9636\u6bb5\u6027\u6210\u679c\u3002\u81ea2024\u5e74\u542f\u52a8\u4ee5\u6765\uff0c\u9879\u76ee\u4e0d\u65ad\u62d3\u5c55\u548c\u6df1\u5316\u30022026\u5e74\uff0c\u8be5\u9879\u76ee\u56f4\u7ed5\u300a\u4e2d\u56fd\u9632\u6cbb\u75c5\u6bd2\u6027\u809d\u708e\u884c\u52a8\u8ba1\u5212\uff082025\u20142030\u5e74\uff09\u300b\u548c\u300a\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u8005\u533b\u7597\u673a\u6784\u5185\u7ba1\u7406\u6d41\u7a0b\u4e13\u5bb6\u5171\u8bc6\u300b\u5f00\u5c55\u5e7f\u6cdb\u5b66\u672f\u4ea4\u6d41\u7684\u540c\u65f6\uff0c\u79ef\u6781\u63a8\u52a8\u533b\u9662\u4ee5\u809d\u75c5\u3001\u611f\u67d3\u7b49\u4e13\u79d1\u79d1\u5ba4\u4e3a\u4e2d\u5fc3\uff0c\u8054\u52a8\u804c\u80fd\u79d1\u5ba4\u3001\u975e\u4e13\u79d1\u4e34\u5e8a\u79d1\u5ba4\u53ca\u5176\u4ed6\u76f8\u5173\u79d1\u5ba4\uff0c\u63a2\u7d22\u9662\u5185\u4e59\u809d\u60a3\u8005\u68c0\u6d4b\u3001\u8f6c\u8bca\u3001\u6cbb\u7597\u4e0e\u968f\u8bbf\u7684\u95ed\u73af\u7ba1\u7406\uff1b\u540c\u65f6\u652f\u6301\u897f\u90e8\u5730\u533a\u4e34\u5e8a\u80fd\u529b\u548c\u5b66\u79d1\u5efa\u8bbe\uff0c\u52a9\u529b\u6162\u4e59\u809d\u533a\u57df\u8bca\u7597\u80fd\u529b\u5747\u8861\u53d1\u5c55\u3002 \u76ee\u524d\uff0c\u8be5\u9879\u76ee\u5df2\u8986\u76d6\u56fd\u518564\u5bb6\u91cd\u70b9\u533b\u9662\uff0c\u672a\u6765\u8fd8\u5c06\u7ee7\u7eed\u6269\u5927\u8986\u76d6\u8303\u56f4\uff0c\u5e76\u9010\u6b65\u63a2\u7d22\u533b\u9662\u4e0e\u75be\u63a7\u3001\u793e\u533a\u7b49\u9662\u5916\u4f53\u7cfb\u7684\u8054\u52a8\uff0c\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u9662\u5185\u5916\u9632\u6cbb\u8854\u63a5\uff0c\u4e3a\u63d0\u5347\u6162\u4e59\u809d\u8bca\u7597\u6c34\u5e73\u3001\u63a8\u52a8\u6211\u56fd\u5b9e\u73b0\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u516c\u5171\u536b\u751f\u5371\u5bb3\u7684\u76ee\u6807\u8d21\u732e\u529b\u91cf\u3002 \u4e19\u578b\u809d\u708e\uff08\u7b80\u79f0\u4e19\u809d\uff09\u76ee\u524d\u53ef\u901a\u8fc7\u89c4\u8303\u7684\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\u3002\u4f46\u5728\u8fc7\u53bb\u5f88\u957f\u4e00\u6bb5\u65f6\u95f4\uff0c\u6211\u56fd\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u53ef\u9009\u62e9\u7684\u6cbb\u7597\u65b9\u6848\u6781\u4e3a\u6709\u9650\u3002\u5982\u679c\u672a\u80fd\u83b7\u5f97\u53ca\u65f6\u8bca\u7597\uff0c\u4e19\u809d\u60a3\u513f\u4e0d\u4ec5\u53ef\u80fd\u9762\u4e34\u75be\u75c5\u6301\u7eed\u8fdb\u5c55\u7684\u98ce\u9669\uff0c\u75be\u75c5\u4e5f\u53ef\u80fd\u7ed9\u5176\u6210\u957f\u548c\u5fc3\u7406\u5065\u5eb7\u5e26\u6765\u957f\u671f\u5f71\u54cd\u30022025\u5e742\u6708\uff0c\u5728&#8221;\u5148\u884c\u5148\u8bd5&#8221;\u653f\u7b56\u652f\u6301\u4e0b\uff0c\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\u83b7\u6279\uff0c\u586b\u8865\u4e86\u6211\u56fd3\u81f312\u5c81\u513f\u7ae5\u4e19\u809d\u60a3\u8005\u6cdb\u57fa\u56e0\u578b\u6297\u75c5\u6bd2\u6cbb\u7597\u7684\u7528\u836f\u7a7a\u767d\u3002 \u672c\u5c4a\u8fdb\u535a\u4f1a\u671f\u95f4\uff0c\u4e2d\u56fd\u4e19\u809d\u60a3\u513f\u6cbb\u7597\u65b0\u5e0c\u671b\u6210\u679c\u5c55\u793a\u4f1a\u5728\u5409\u5229\u5fb7\u5c55\u53f0\u4e3e\u884c\uff0c\u6811\u5170\uff08\u535a\u9ccc\uff09\u533b\u9662\u6881\u5fd7\u519b\u6559\u6388\u5206\u4eab\u4e86\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u6d77\u5357\u535a\u9ccc\u4e50\u57ce\u843d\u5730\u4e00\u5e74\u591a\u6765\u7684\u5b9e\u8df5\u8fdb\u5c55\u3002\u622a\u81f3\u76ee\u524d\uff0c\u5df2\u6709\u591a\u540d\u4e19\u809d\u60a3\u513f\u901a\u8fc7\u8be5\u836f\u7269\u6cbb\u7597\u5b9e\u73b0\u75c5\u6bd2\u5b66\u6cbb\u6108\uff0c\u62e5\u62b1\u5065\u5eb7\u7ae5\u5e74\u3002\u4eca\u5e7410\u6708\uff0c\u6881\u5fd7\u519b\u6559\u6388\u53ca\u5176\u56e2\u961f\u53d1\u8868\u4e86\u300a\u7d22\u78f7\u5e03\u97e6\/\u7ef4\u5e15\u4ed6\u97e6\uff08SOF\/VEL\uff09\u9897\u7c92\u5242\u6cbb\u7597\u513f\u7ae5\u6162\u6027\u4e19\u578b\u809d\u708e\u7684\u521d\u6b65\u7597\u6548\u4e0e\u5b89\u5168\u6027\uff1a\u6d77\u5357\u535a\u9ccc\u5148\u884c\u5148\u8bd5\u533a\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u300b\uff0c\u5c06\u5148\u884c\u5148\u8bd5\u79ef\u7d2f\u7684\u5b9d\u8d35\u4e34\u5e8a\u5b9e\u8df5\u8fdb\u4e00\u6b65\u8f6c\u5316\u4e3a\u53ef\u4f9b\u66f4\u591a\u4e34\u5e8a\u533b\u751f\u53c2\u8003\u7684\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u3002\u7814\u7a76\u663e\u793a\uff0c\u5728\u5b8c\u6210\u968f\u8bbf\u768413\u4f8b\u60a3\u513f\u4e2d\uff0c\u6cbb\u7597\u7ed3\u675f\u540e12\u5468\u6301\u7eed\u75c5\u6bd2\u5b66\u5e94\u7b54\u7387\u8fbe100%\uff0c\u672a\u89c2\u5bdf\u5230\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4e5f\u672a\u53d1\u751f\u56e0\u4e0d\u826f\u4e8b\u4ef6\u5bfc\u81f4\u7684\u505c\u836f\u6216\u6cbb\u7597\u4e2d\u65ad[3]\u3002\u8fd9\u4e5f\u662f\u4e19\u901a\u6c99\u00ae\u53e3\u670d\u5fae\u4e38\u5728\u4e2d\u56fd\u60a3\u513f\u4e2d\u5e94\u7528\u7684\u9996\u7bc7\u771f\u5b9e\u4e16\u754c\u6570\u636e\u3002 \u7b5b\u67e5\u662f\u63a8\u52a8\u75c5\u6bd2\u6027\u809d\u708e\u9632\u6cbb\u7684\u91cd\u8981\u4e00\u73af\u3002\u672c\u5c4a\u8fdb\u535a\u4f1a\u4e0a\uff0c\u5409\u5229\u5fb7\u79d1\u5b66\u4e0e\u91d1\u57df\u533b\u5b66\u518d\u6b21\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\uff0c\u53cc\u65b9\u5c06\u7ee7\u7eed\u53d1\u6325\u5404\u81ea\u4e13\u957f\u548c\u8d44\u6e90\u4f18\u52bf\uff0c\u5e2e\u52a9\u516c\u4f17\u63d0\u5347\u4e3b\u52a8\u7b5b\u67e5\u610f\u8bc6\uff0c\u4e86\u89e3\u81ea\u8eab\u5065\u5eb7\u72b6\u51b5\uff0c\u5e76\u63a8\u52a8\u6709\u9700\u8981\u7684\u7fa4\u4f53\u5c3d\u65e9\u83b7\u5f97\u89c4\u8303\u8bca\u7597\u3002 \u9664\u4e86\u521b\u65b0\u7597\u6cd5\u4e0e\u5408\u4f5c\u6210\u679c\uff0c\u5409\u5229\u5fb7\u5c55\u53f0\u8fd8\u5448\u73b0\u4e86\u591a\u4f4d\u771f\u5b9e\u60a3\u8005\u7684\u6545\u4e8b\uff0c\u5176\u4e2d\u6709\u4ece\u89c4\u8303\u6cbb\u7597\u4e2d\u91cd\u83b7\u751f\u6d3b\u5e0c\u671b\u7684\u6162\u4e59\u809d\u60a3\u8005\uff0c\u6709\u6210\u529f\u6218\u80dc\u4e19\u809d\u7684\u513f\u7ae5\uff0c\u4e5f\u6709\u901a\u8fc7\u81ea\u8eab\u529b\u91cf\u5e2e\u52a9\u66f4\u591a\u75c5\u53cb\u7684PBC\u60a3\u8005\u3002\u8fd9\u4e9b\u6545\u4e8b\uff0c\u8ba9\u809d\u75c5\u9632\u6cbb\u7684\u610f\u4e49\u66f4\u52a0\u5177\u4f53\u53ef\u611f\uff0c\u4e5f\u8ba9\u66f4\u591a\u4eba\u770b\u5230\u75be\u75c5\u80cc\u540e\u79ef\u6781\u751f\u6d3b\u7684\u4e2a\u4f53\uff0c\u4ee5\u53ca\u79d1\u5b66\u7a81\u7834\u548c\u89c4\u8303\u8bca\u7597\u4e3a\u60a3\u8005\u751f\u6d3b\u5e26\u6765\u7684\u5207\u5b9e\u6539\u53d8\u3002 \u4ece\u5371\u5bb3\u516c\u4f17\u5065\u5eb7\u7684\u75c5\u6bd2\u6027\u809d\u708e\u5230\u9700\u8981\u66f4\u591a\u4eba\u5173\u6ce8\u7684\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u6301\u7eed\u4ee5\u79d1\u5b66\u521b\u65b0\u56de\u5e94\u672a\u6ee1\u8db3\u7684\u6cbb\u7597\u9700\u6c42\uff0c\u4ee5\u591a\u65b9\u5408\u4f5c\u63a8\u52a8\u521b\u65b0\u6210\u679c\u771f\u6b63\u60e0\u53ca\u60a3\u8005\u3002\u672a\u6765\uff0c\u5409\u5229\u5fb7\u5c06\u7ee7\u7eed\u4e0e\u793e\u4f1a\u5404\u754c\u4f19\u4f34\u643a\u624b\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u7684\u5efa\u8bbe\u8d21\u732e\u529b\u91cf\u3002 \u5409\u5229\u5fb7\u8fdb\u535a\u4f1a\u5c55\u53f0\u4fe1\u606f\uff1a \u56fd\u5bb6\u4f1a\u5c55\u4e2d\u5fc3 \u533b\u7597\u5668\u68b0\u53ca\u533b\u836f\u4fdd\u5065\u5c55\u533a1.1H \u5c55\u4f4d\u53f7\uff1a1.1A3-02 [1] Hirschfield GM, Bowlus CL, Mayo MJ, et al. A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis. N Engl J Med. 2024;390(9):783-794. [2] https:\/\/www.gilead.com\/news\/news-details\/2026\/positive-phase-3-ideal-study-results-further-support-livdelzis-seladelpar-impact-on-achieving-alp-normalization-goals-in-second-line-treatment-across-a-broad-population-of-people-living-with [3] \u6881\u5fd7\u519b, \u7b49. \u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a\u5b66\u672f\u5e74\u4f1a\u66a8\u4e2d\u9752\u5e74\u5b66\u672f\u4f1a\u8bae, [&hellip;]","og_url":"https:\/\/moneycompass.com.my\/cn\/\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\/","og_site_name":"Money Compass CN","article_published_time":"2026-11-08T13:17:00+00:00","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/","url":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/","name":"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c - Money Compass CN","isPartOf":{"@id":"https:\/\/moneycompass.com.my\/cn\/#website"},"primaryImageOfPage":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage"},"image":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage"},"thumbnailUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg","datePublished":"2026-11-08T13:17:00+00:00","dateModified":"2026-11-08T13:17:00+00:00","author":{"@id":""},"breadcrumb":{"@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#primaryimage","url":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg","contentUrl":"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2026\/11\/20261108065549EST_image_1-MTDAqO.jpeg","width":144,"height":96},{"@type":"BreadcrumbList","@id":"https:\/\/moneycompass.com.my\/cn\/%e4%bb%8e%e7%97%85%e6%af%92%e6%80%a7%e8%82%9d%e7%82%8e%e5%88%b0%e7%bd%95%e8%a7%81%e8%82%9d%e7%97%85%ef%bc%8c%e5%90%89%e5%88%a9%e5%be%b7%e6%90%ba%e6%89%8b%e5%a4%9a%e6%96%b9%e5%85%b1%e8%af%9d%e8%82%9d\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/moneycompass.com.my\/cn\/"},{"@type":"ListItem","position":2,"name":"\u4ece\u75c5\u6bd2\u6027\u809d\u708e\u5230\u7f55\u89c1\u809d\u75c5\uff0c\u5409\u5229\u5fb7\u643a\u624b\u591a\u65b9\u5171\u8bdd\u809d\u75c5\u9632\u6cbb\u65b0\u6210\u679c"}]},{"@type":"WebSite","@id":"https:\/\/moneycompass.com.my\/cn\/#website","url":"https:\/\/moneycompass.com.my\/cn\/","name":"Money Compass CN","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/moneycompass.com.my\/cn\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/32090"}],"collection":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/comments?post=32090"}],"version-history":[{"count":0,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/posts\/32090\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media\/32091"}],"wp:attachment":[{"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/media?parent=32090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/categories?post=32090"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/moneycompass.com.my\/cn\/wp-json\/wp\/v2\/tags?post=32090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}