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The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden of disease study 2019. Biomed Eng Online. 2022 Jan 11;21(1):4. DOI: 10.1186\/s12938-021-00973-6<\/p>\n<p>2.\u00a0\u00a0\u00a0\u00a0 \u5218\u6f8e. \u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u7ec6\u80de\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\u8bca\u7597\u89c4\u8303\uff08v1.2018\uff09[J].\u4e2d\u56fd\u4e34\u5e8a\u533b\u5b66, 2018, 25(1): 157-160. DOI: 10.12015\/j. issn. 1008-6358. 2018. 20180<\/p>\n<p>3.\u00a0\u00a0\u00a0\u00a0 \u674e\u5efa\u52c7, \u90b1\u5f55\u8d35. \u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u8840\u6db2\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a,\u4e2d\u534e\u533b\u5b66\u4f1a\u8840\u6db2\u5b66\u5206\u4f1a.\u4e2d\u56fd\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u8bca\u65ad\u4e0e\u6cbb\u7597\u6307\u5357\uff082022\u5e74\u7248\uff09. \u4e2d\u534e\u8840\u6db2\u5b66\u6742\u5fd7, 2022,43(5) : 353-358. 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CLL\/SLL\u60a3\u8005\u7684\u6cbb\u7597\u662f\u76ee\u524d\u5168\u7403\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0cAPG-2575\u8d70\u5230\u8fd9\u4e00\u5173\u952e\u8282\u70b9\uff0c\u4f53\u73b0\u4e86\u4e9a\u76db\u533b\u836f\u5728\u5168\u7403\u533b\u836f\u9886\u57df\u7684\u521b\u65b0\u5b9e\u529b\u3002\u6211\u4eec\u5c06\u52a0\u901fAPG-2575\u5728\u5168\u7403\u5c42\u9762\u591a\u9002\u5e94\u75c7\u9886\u57df\u7684\u5f00\u53d1\uff0c\u66f4\u5feb\u5730\u9020\u798f\u60a3\u8005\u3002\u540c\u65f6\u4e9a\u76db\u4e5f\u5c06\u7ee7\u7eed\u575a\u5b88\u2018\u89e3\u51b3\u4e2d\u56fd\u4e43\u81f3\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42&#8217;\u7684\u4f7f\u547d\uff0c\u5e26\u6765\u66f4\u591a\u91cd\u78c5\u521b\u65b0\u836f\u7269\uff0c\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002&#8221; \u53c2\u8003\u8d44\u6599\uff1a 1.\u00a0\u00a0\u00a0\u00a0 Yao, Y., Lin, X., Li, F., et al. The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":4433,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-4432","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u9996\u4e2a\u56fd\u4ea7\u539f\u7814Bcl-2\u6291\u5236\u5242\uff01\u4e9a\u76db\u533b\u836fAPG-2575\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u53d7\u7406\u5e76\u88ab\u63a8\u8350\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4 - Money Compass CN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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CLL\/SLL\u662f\u4e00\u79cd\u6210\u719fB\u6dcb\u5df4\u7ec6\u80de\u514b\u9686\u589e\u6b96\u6027\u80bf\u7624\uff0c\u591a\u53d1\u4e8e\u8001\u5e74\u60a3\u8005\uff0c\u662f\u897f\u65b9\u56fd\u5bb6\u6700\u5e38\u89c1\u7684\u6210\u4eba\u767d\u8840\u75c5\u7c7b\u578b\uff0c\u5168\u7403\u6bcf\u5e74\u65b0\u589e\u75c5\u4f8b\u8d85\u8fc710\u4e07\u4f8b1\u3002\u4e2d\u56fdCLL\/SLL\u7684\u53d1\u75c5\u7387\u76f8\u5bf9\u6b27\u7f8e\u56fd\u5bb6\u8f83\u4f4e\uff0c\u4f46\u5448\u660e\u663e\u4e0a\u5347\u8d8b\u52bf\uff0c\u4e14\u5177\u6709\u53d1\u75c5\u5e74\u9f84\u4f4e\u3001\u4fb5\u88ad\u5ea6\u9ad8\u7b49\u7279\u70b92\u3002SLL\u4e0eCLL\u662f\u540c\u4e00\u79cd\u75be\u75c5\u7684\u4e0d\u540c\u8868\u73b0\uff0c\u7ea620\uff05\u7684SLL\u8fdb\u5c55\u4e3aCLL3\u3002\u5c3d\u7ba1\u514d\u75ab\u5316\u7597\u53ca\u5e03\u9c81\u987f\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08BTKi\uff09\u7b49\u6cbb\u7597\u624b\u6bb5\u660e\u663e\u63d0\u9ad8\u4e86CLL\/SLL\u60a3\u8005\u521d\u6cbb\u7f13\u89e3\u7387\uff0c\u4f46\u56e0\u73b0\u6709\u6cbb\u7597\u65b9\u6cd5\u7684\u5c40\u9650\u3001\u60a3\u8005\u9884\u540e\u4e0d\u4f73\u3001\u75be\u75c5\u5bf9\u751f\u6d3b\u8d28\u91cf\u7684\u4e25\u91cd\u5f71\u54cd\u548c\u80bf\u7624\u672c\u8eab\u7684\u590d\u6742\u6027\u7b49\u539f\u56e0\uff0cr\/r CLL\/SLL\u60a3\u8005\u4ecd\u8feb\u5207\u9700\u8981\u66f4\u5b89\u5168\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\u3002 Bcl-2\u6291\u5236\u5242\u7684\u51fa\u73b0\u8ba9CLL\/SLL\u7684\u6cbb\u7597\u6709\u4e86\u8fdb\u4e00\u6b65\u7684\u9769\u65b0\u3002Bcl-2\u662f\u4e00\u79cd\u51cb\u4ea1\u6291\u5236\u56e0\u5b50\uff0c\u53ef\u4ee5\u63a7\u5236\u7ebf\u7c92\u4f53\u819c\u901a\u900f\u6027\u6765\u8c03\u8282\u7ec6\u80de\u5b58\u6d3b\uff0c\u901a\u8fc7\u6291\u5236\u7ebf\u7c92\u4f53\u7ec6\u80de\u8272\u7d20C\u7684\u91ca\u653e\uff0c\u6216\u8005\u7ed3\u5408\u51cb\u4ea1\u6fc0\u6d3b\u56e0\u5b50\uff0c\u6765\u6291\u5236\u51cb\u4ea1\u86cb\u767d\u9176\u7684\u6d3b\u6027\u3002Bcl-2\u5728\u8bb8\u591a\u6076\u6027\u8840\u6db2\u80bf\u7624\u7279\u522b\u662fCLL\/SLL\u4e2d\u8fc7\u5ea6\u8868\u8fbe\uff0c\u662f\u80bf\u7624\u7ec6\u80de\u9003\u907f\u51cb\u4ea1\u7684\u91cd\u8981\u673a\u5236\u4e4b\u4e00\u3002 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PPI)\uff0c\u9776\u70b9\u7ed3\u5408\u754c\u9762\u6bd4\u8f83\u5927\uff0c\u5f88\u96be\u8bbe\u8ba1\u5c0f\u5206\u5b50\u53bb\u6291\u5236\u5e76\u53d1\u6325\u963b\u65ad\u4f5c\u7528\u3002\u6b64\u5916\uff0cBcl-2\u9776\u70b9\u4f4d\u4e8e\u7ebf\u7c92\u4f53\u819c\u4e0a\uff0c\u7ebf\u7c92\u4f53\u662f\u53cc\u819c\u7ed3\u6784\uff0c\u5c5e\u4e8e\u7ec6\u80de\u4e2d\u7ed3\u6784\u6700\u590d\u6742\u3001\u6700\u96be\u7684\u90e8\u5206\u4e4b\u4e00\uff0c\u836f\u7269\u9700\u8981\u5148\u901a\u8fc7\u7ec6\u80de\u819c\u8fdb\u5165\u7ec6\u80de\u540e\u624d\u80fd\u8fdb\u4e00\u6b65\u4f5c\u7528\u4e8e\u7ebf\u7c92\u4f53\u819c\u4e0a\uff0c\u8fd9\u65e0\u7591\u66f4\u52a0\u5927\u6210\u836f\u96be\u5ea6\u3002\u9776\u70b9\u53d1\u73b0\u81f3\u4eca\u8fd140\u5e74\uff0c\u5168\u7403\u53ea\u6709\u4e00\u6b3e\u9776\u5411Bcl-2\u7684\u6291\u5236\u5242\u83b7\u6279\u4e0a\u5e02\uff0c\u5145\u5206\u5c55\u73b0\u4e86\u8be5\u9886\u57df\u7684\u7814\u53d1\u96be\u5ea6\u4e0e\u6311\u6218\u3002\u56fd\u5916CLL\/SLL\u6cbb\u7597\u5df2\u8fdb\u5165\u4e86&#8221;\u65e0\u5316\u7597&#8221;\u3001&#8221;\u56fa\u5b9a\u7597\u7a0b&#8221;\u7684\u65b0\u65f6\u4ee3\uff0c\u800c\u6b64\u524d\u8be5\u6cbb\u7597\u9886\u57df\u5c1a\u672a\u6709\u4efb\u4f55\u4e00\u6b3eBcl-2\u6291\u5236\u5242\u5728\u4e2d\u56fd\u83b7\u6279\uff0c\u56e0\u6b64\u56fd\u5185\u4e5f\u6025\u9700\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002 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CLL\/SLL\u60a3\u8005\u7684\u6cbb\u7597\u662f\u76ee\u524d\u5168\u7403\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0cAPG-2575\u8d70\u5230\u8fd9\u4e00\u5173\u952e\u8282\u70b9\uff0c\u4f53\u73b0\u4e86\u4e9a\u76db\u533b\u836f\u5728\u5168\u7403\u533b\u836f\u9886\u57df\u7684\u521b\u65b0\u5b9e\u529b\u3002\u6211\u4eec\u5c06\u52a0\u901fAPG-2575\u5728\u5168\u7403\u5c42\u9762\u591a\u9002\u5e94\u75c7\u9886\u57df\u7684\u5f00\u53d1\uff0c\u66f4\u5feb\u5730\u9020\u798f\u60a3\u8005\u3002\u540c\u65f6\u4e9a\u76db\u4e5f\u5c06\u7ee7\u7eed\u575a\u5b88\u2018\u89e3\u51b3\u4e2d\u56fd\u4e43\u81f3\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42&#8217;\u7684\u4f7f\u547d\uff0c\u5e26\u6765\u66f4\u591a\u91cd\u78c5\u521b\u65b0\u836f\u7269\uff0c\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002&#8221; \u53c2\u8003\u8d44\u6599\uff1a 1.\u00a0\u00a0\u00a0\u00a0 Yao, Y., Lin, X., Li, F., et al. The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/moneycompass.com.my\/cn\/\u9996\u4e2a\u56fd\u4ea7\u539f\u7814bcl-2\u6291\u5236\u5242\uff01\u4e9a\u76db\u533b\u836fapg-2575\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\/\" \/>\n<meta property=\"og:site_name\" content=\"Money Compass CN\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-17T14:41:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/moneycompass.com.my\/cn\/wp-content\/uploads\/2024\/11\/Ascentage_Pharma_Logo-vXB0yJ.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"144\" \/>\n\t<meta property=\"og:image:height\" content=\"28\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" 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