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\u4e0a\u6d77<\/span>2025\u5e743\u67084\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u7531\u751f\u6210\u5f0f\u4eba\u5de5\u667a\u80fd\uff08AI\uff09\u9a71\u52a8\u7684\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u533b\u836f\u516c\u53f8\u82f1\u77fd\u667a\u80fd\uff0c\u548c\u4e13\u6ce8\u4e8e\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u836f\u7269\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u751f\u7269\u533b\u836f\u516c\u53f8\u5143\u7fbf\u751f\u7269\u4e8e\u8fd1\u671f\u5ba3\u5e03\u8fbe\u6210\u6218\u7565\u7814\u53d1\u5408\u4f5c\u3002\u53cc\u65b9\u5c06\u5728\u65b0\u578b\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff08Central nervous system, CNS\uff09\u75be\u75c5\u7597\u6cd5\u7684\u65e9\u671f\u7814\u53d1\u9636\u6bb5\u5f00\u5c55\u5408\u4f5c\uff0c\u91cd\u70b9\u9488\u5bf9\u6307\u5b9a\u6f5c\u5728\u9776\u70b9\uff0c\u4ece\u96f6\u5f00\u59cb\u5f00\u53d1\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0c\u76f4\u81f3\u63a8\u8fdb\u81f3\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\u63d0\u540d\u3002<\/p>\n

\n

<\/a><\/p>\n<\/div>\n

\u6b64\u6b21\u5408\u4f5c\u4e2d\uff0c\u53cc\u65b9\u5c06\u7ed3\u5408\u82f1\u77fd\u667a\u80fd\u524d\u6cbf\u751f\u6210\u5f0f\u4eba\u5de5\u667a\u80fd\u836f\u7269\u53d1\u73b0\u5e73\u53f0Pharma.AI\u53ca\u5e7f\u6cdb\u836f\u7269\u7814\u53d1\u7ecf\u9a8c\uff0c\u4e0e\u5143\u7fbf\u751f\u7269\u4e13\u4e1a\u79d1\u5b66\u7814\u7a76\u6210\u679c\u53ca\u79ef\u7d2f\u7684\u4e13\u6709\u6570\u636e\u8d44\u4ea7\uff0c\u5173\u6ce8\u5177\u6709\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff08Blood-brain barrier, BBB\uff09\u6f5c\u529b\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\u7684\u5f00\u53d1\uff0c\u5171\u540c\u4e3aCNS\u75be\u75c5\u9886\u57df\u5e26\u6765\u53d8\u9769\u6027\u7684\u521b\u65b0\u6cbb\u7597\u65b9\u6848\u3002\u901a\u8fc7\u5229\u7528\u5148\u8fdb\u7684\u4eba\u5de5\u667a\u80fd\u6280\u672f\uff0c\u53cc\u65b9\u7684\u5408\u4f5c\u65e8\u5728\u62d3\u5c55\u5168\u7403\u60a3\u8005\u7684\u6cbb\u7597\u9009\u62e9\u3001\u5e76\u4f18\u5316\u4e34\u5e8a\u83b7\u76ca\u3002<\/p>\n

\u5143\u7fbf\u751f\u7269\u662f\u4e00\u5bb6\u4ee5CNS\u836f\u7269\u5f00\u53d1\u4e3a\u4e13\u573a\u7684\u751f\u7269\u533b\u836f\u516c\u53f8<\/span>\uff0c\u51ed\u501f\u5bf9\u590d\u6742\u751f\u7269\u901a\u8def\u7684\u6df1\u5165\u7406\u89e3\u548c\u5bf9\u9776\u70b9\u751f\u7269\u5b66\u7684\u91cd\u89c6\uff0c\u8be5\u516c\u53f8\u4e13\u6ce8\u63d0\u4f9b\u53d8\u9769\u6027\u89e3\u51b3\u65b9\u6848\u3002\u57fa\u4e8e\u8fc7\u53bb\u7684\u7814\u7a76\u5408\u4f5c\u4e0e\u79d1\u7814\u6210\u679c\u8f6c\u5316\uff0c\u5143\u7fbf\u751f\u7269\u5df2\u6210\u529f\u7814\u53d1\u591a\u6b3e\u521b\u65b0\u7597\u6cd5\u3002<\/p>\n

\u82f1\u77fd\u667a\u80fd\u4e8e2016\u5e74\u5728\u540c\u884c\u8bc4\u8bae\u671f\u520a\u4e2d\u9996\u6b21\u63cf\u8ff0\u4e86\u4f7f\u7528\u751f\u6210\u5f0f\u4eba\u5de5\u667a\u80fd\u8bbe\u8ba1\u65b0\u5206\u5b50\u7684\u6982\u5ff5\uff0c\u968f\u540e\u6210\u529f\u5f00\u53d1\u5546\u4e1a\u5316Pharma.AI\u5e73\u53f0\u3002\u81ea2021\u5e74\u6765\uff0c\u8be5\u5e73\u53f0\u652f\u6301\u4e86\u82f1\u77fd\u667a\u80fd\u81ea\u4e3b\u642d\u5efa\u768430\u4f59\u6761\u81ea\u6709\u7ba1\u7ebf\uff0c\u5176\u4e2d10\u4e2a\u836f\u7269\u5206\u5b50\u5df2\u83b7\u5f97\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\uff0c\u4e3a\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684\u836f\u7269\u53d1\u73b0\u548c\u5f00\u53d1\u6811\u7acb\u4e86\u6807\u6746\u3002CNS\u662f\u82f1\u77fd\u667a\u80fd\u5173\u6ce8\u7684\u5173\u952e\u75be\u75c5\u9886\u57df\u4e4b\u4e00\u3002<\/p>\n

\u5143\u7fbf\u751f\u7269\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98\u9648\u5c0f\u7965\u535a\u58eb\u8868\u793a\uff0c”\u968f\u7740\u591a\u6761\u7ba1\u7ebf\u8fdb\u5165\u4e34\u5e8a\u9636\u6bb5\uff0c\u6211\u4eec\u671f\u5f85\u8fdb\u4e00\u6b65\u6269\u5927\u9488\u5bf9CNS\u75be\u75c5\u7684\u6cbb\u7597\u7ec4\u5408\uff0c\u6b64\u6b21\u4e0e\u82f1\u77fd\u667a\u80fd\u7684\u5408\u4f5c\u6709\u671b\u52a9\u529b\u8fd9\u4e00\u613f\u666f\u3002\u5728\u82f1\u77fd\u667a\u80fd\u521b\u65b0\u4eba\u5de5\u667a\u80fd\u5e73\u53f0\u7684\u652f\u6301\u4e0b\uff0c\u5143\u7fbf\u751f\u7269\u5728CNS\u751f\u7269\u5b66\u548c\u4e34\u5e8a\u5f00\u53d1\u65b9\u9762\u7684\u4e13\u4e1a\u77e5\u8bc6\u6709\u671b\u4e3a\u6cbb\u7597\u8303\u5f0f\u7684\u8f6c\u53d8\u505a\u51fa\u66f4\u5927\u8d21\u732e\u3002”<\/p>\n

\u82f1\u77fd\u667a\u80fd\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98Alex Zhavoronkov<\/span>\u535a\u58eb\u8868\u793a\uff0c”\u6211\u5f88\u9ad8\u5174\u770b\u5230\u6b64\u6b21\u5408\u4f5c\u7684\u8fbe\u6210\uff0c\u5b83\u6807\u5fd7\u7740\u4eba\u5de5\u667a\u80fd\u5728\u836f\u7269\u53d1\u73b0\u9886\u57df\u8fc8\u51fa\u5c55\u73b0\u53d8\u9769\u6027\u6f5c\u80fd\u7684\u53c8\u4e00\u6b65\u3002\u901a\u8fc7\u6b64\u6b21\u5408\u4f5c\uff0c\u6211\u4eec\u5c06\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u751f\u6210\u5f0f\u4eba\u5de5\u667a\u80fd\u6280\u672f\u4e0e\u7ec6\u5206\u9886\u57df\u4e13\u4e1a\u77e5\u8bc6\u7684\u7ed3\u5408\uff0c\u5982\u4f55\u4e3aCNS\u75be\u75c5\u6cbb\u7597\u5e26\u6765\u65b0\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u5c24\u5176\u662f\u514b\u670d\u8840\u8111\u5c4f\u969c\u7a7f\u900f\u6027\u6311\u6218\u3002”<\/p>\n

\u8fd1\u671f\uff0c\u82f1\u77fd\u667a\u80fd\u5ba3\u5e03\u63d0\u540d\u53ef\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684NLRP3\u6291\u5236\u5242ISM8969\uff0c\u7528\u4e8e\u6cbb\u7597\u5305\u62ec\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u766b\u75eb\u5728\u5185\u7684\u708e\u75c7\u76f8\u5173\u75be\u75c5\uff0c\u8fdb\u4e00\u6b65\u4e30\u5bcc\u4e86\u82f1\u77fd\u667a\u80fd\u9488\u5bf9CNS\u75be\u75c5\u548c\u8870\u8001\u76f8\u5173\u75be\u75c5\u7684\u4ea7\u54c1\u7ec4\u5408\u3002\u901a\u8fc7\u6574\u5408\u5148\u8fdb\u7684AI\u548c\u81ea\u52a8\u5316\u6280\u672f\uff0c\u82f1\u77fd\u667a\u80fd\u5728\u5b9e\u9645\u5e94\u7528\u6848\u4f8b\u4e2d\u5c55\u73b0\u51fa\u6548\u7387\u63d0\u5347\uff0c\u4e3aAI\u9a71\u52a8\u7684\u836f\u7269\u7814\u53d1\u6811\u7acb\u4e86\u6807\u6746\u3002\u4e0e\u4f20\u7edf\u836f\u7269\u7814\u53d1\u901a\u5e38\u9700\u89812.5-4\u5e74\u7684\u65f6\u95f4\u5468\u671f\u76f8\u6bd4\uff0c\u82f1\u77fd\u667a\u80fd\u57282021\u81f32024\u5e74\u95f4\u7684\u81ea\u7814\u9879\u76ee\uff0c\u4ece\u7acb\u9879\u5230\u63d0\u540d\u4e34\u5e8a\u524d\u5019\u9009\u836f\u7269\uff08PCC\uff09\u7684\u5e73\u5747\u8017\u65f6\u4e3a12-18\u4e2a\u6708\u4e4b\u95f4\uff0c\u6bcf\u4e2a\u9879\u76ee\u4ec5\u9700\u5408\u6210\u548c\u6d4b\u8bd5\u7ea660-200\u4e2a\u5206\u5b50\uff0c\u4ecePCC\u5230IND-enabling\u9636\u6bb5\u7684\u6210\u529f\u7387\u8fbe\u5230100%\u3002\u00a0<\/p>\n

2024\u5e74\u521d\uff0c\u82f1\u77fd\u667a\u80fd\u5728Nature Biotechnology<\/a>\u53d1\u5e03\u8bba\u6587\uff0c\u4ecb\u7ecd\u4e86\u9886\u5148\u81ea\u7814AI\u836f\u7269ISM001-055\u4ece\u4eba\u5de5\u667a\u80fd\u7b97\u6cd5\u5230II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6574\u4e2a\u7814\u53d1\u5386\u7a0b\u3002\u8be5\u5019\u9009\u836f\u7269\u5177\u6709\u4eba\u5de5\u667a\u80fd\u53d1\u73b0\u7684\u9776\u70b9\u548c\u4eba\u5de5\u667a\u80fd\u8bbe\u8ba1\u7684\u7ed3\u6784\uff0c\u9488\u5bf9\u5176\u8fdb\u884c\u8bc4\u4f30\u7684\u4e00\u9879IIa\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT05938920\uff09\u4e8e\u8fd1\u671f\u53d1\u5e03\u79ef\u6781\u521d\u6b65\u7ed3\u679c<\/a>\u3002\u6570\u636e\u8868\u660e\uff0cISM001-055\u5728\u7528\u836f12\u5468\u540e\u663e\u793a\u51fa\u5168\u5242\u91cf\u7ec4\u4e2d\u7684\u826f\u597d\u5b89\u5168\u6027\u548c\u7528\u529b\u80ba\u6d3b\u91cf\uff08FVC\uff09\u7684\u5242\u91cf\u4f9d\u8d56\u6027\u836f\u6548\u8d8b\u52bf<\/a>\u3002\u00a0<\/p>\n

###<\/p>\n

\u5173\u4e8e\u82f1\u77fd\u667a\u80fd<\/p>\n

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\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u7f51\u7ad9
www.insilico.com<\/a><\/p>\n

\u5546\u52a1\u5408\u4f5c\uff0c\u8bf7\u8054\u7cfb\u00a0bd@insilico.ai<\/span><\/a>
\u5a92\u4f53\u5782\u8be2\uff0c\u8bf7\u8054\u7cfb\u00a0pr@insilico.ai<\/a>\u00a0<\/span><\/p>\n

\u5173\u4e8e\u5143\u7fbf\u751f\u7269<\/p>\n

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\n<\/div>\n

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href=\"https:\/\/moneycompass.com.my\/cn\/\u82f1\u77fd\u667a\u80fd\u4e0e\u5143\u7fbf\u751f\u7269\u5ba3\u5e03\u8fbe\u6210\u7814\u53d1\u5408\u4f5c\uff0c\u4ee5\u751f\u6210\u5f0f\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u82f1\u77fd\u667a\u80fd\u4e0e\u5143\u7fbf\u751f\u7269\u5ba3\u5e03\u8fbe\u6210\u7814\u53d1\u5408\u4f5c\uff0c\u4ee5\u751f\u6210\u5f0f\u4eba\u5de5\u667a\u80fd\u8d4b\u80fd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u836f\u7269\u7814\u53d1 - Money Compass CN\" \/>\n<meta property=\"og:description\" content=\"\u4e0a\u6d772025\u5e743\u67084\u65e5 \/\u7f8e\u901a\u793e\/ — 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