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rel=\"noopener\">\u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>\uff08&#8221;\u817e\u76db\u535a\u836f&#8221;\u6216&#8221;\u516c\u53f8&#8221;\uff0c\u80a1\u7968\u4ee3\u7801\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u4e8e\u9488\u5bf9\u60a3\u8005\u533b\u7597\u9700\u6c42\u672a\u88ab\u6ee1\u8db3\u7684\u75be\u75c5\u5f00\u53d1\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u5065\u5eb7\u72b6\u51b5\u548c\u6cbb\u7597\u9009\u62e9\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4eca\u65e5\u53d1\u5e03\u6700\u65b0\u516c\u53f8\u8fdb\u5c55\u5e76\u62a5\u544a\u622a\u81f32024\u5e7412\u670831\u65e5\u7684\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<p>\n                        <a href=\"https:\/\/mma.prnewswire.com\/media\/1690538\/Logo.html\" target=\"_blank\" rel=\"noopener\"><\/a><\/p>\n<p>                        \n                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\u5e74\u95f4\u83b7\u5f97\u5173\u952e\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u4e3a\u540e\u671f\u7814\u7a76\u63d0\u4f9b\u4fe1\u606f\u3002<\/p>\n<p>ENHANCE\u7814\u7a76\uff1a2025\u5e741\u6708\u5b8c\u6210\u5165\u7ec4\u3002\u8be52b\u671f\u968f\u673a\u53cc\u76f2\u7814\u7a76\u8bc4\u4f30BRII-179\u3001elebsiran\u8054\u5408PEG-IFN\u03b1\u5bf9\u6bd4PEG-IFN\u03b1\u5355\u836f\u5728\u975e\u809d\u786c\u5316\u6162\u6027HBV\u611f\u67d3\u60a3\u8005\uff08\u63a5\u53d7\u6838\u82f7\u9178\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTI\uff09\u80cc\u666f\u6cbb\u7597\uff09\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u3002ENSURE\u7814\u7a76\uff1a\u57282024\u5e7411\u6708\u4e3e\u884c\u7684\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u817e\u76db\u535a\u836f\u4ee5\u6700\u65b0\u7a81\u7834\u6027\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u4e86ENSURE\u7814\u7a7648\u5468\u6cbb\u7597\u7ed3\u675f\u65f6\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0celebsiran\u8054\u5408PEG-IFN\u03b1\u6cbb\u7597\u7ec4\u60a3\u8005\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387\u663e\u8457\u9ad8\u4e8e\u5e72\u6270\u7d20\u5355\u836f\u7ec4\u3002ENSURE\u7814\u7a76\u6807\u5fd7\u7740\u4e1a\u5185\u9996\u6b21\u901a\u8fc7\u4e0e\u5e72\u6270\u7d20\u5355\u836f\u5934\u5bf9\u5934\u7684\u6bd4\u8f83\uff0c\u660e\u786e\u4e86siRNA\uff08elebsiran\uff09\u5728\u4e0e\u5e72\u6270\u7d20\u8054\u7528\u65f6\u5bf9\u529f\u80fd\u6027\u6cbb\u6108\u7684\u8d21\u732e\uff0c\u51f8\u663e\u5176\u63d0\u5347HBV\u529f\u80fd\u6027\u6cbb\u6108\u7387\u7684\u6f5c\u529b\u3002\u817e\u76db\u535a\u836f\u5c06\u4e8e2025\u5e74\u4e0a\u534a\u5e74\u516c\u5e03\u66f4\u591a\u5173\u952e\u6570\u636e\u3002ENRICH\u7814\u7a76\uff1aENSURE \u7814\u7a76\u8fd8\u5bf9\u66fe\u63a5\u53d7\u8fc7 BRII-179 \u6cbb\u7597\u7684\u60a3\u8005\u8fdb\u884c\u4e86\u7814\u7a76\u3002\u57fa\u4e8eENSURE\u7814\u7a76\u961f\u52174\u7684\u65e9\u671f\u6570\u636e\uff08\u5c06\u4e8e2025\u5e74APASL\u516c\u5e03\uff09\uff0cENRICH\u7814\u7a76\u4e8e2024\u5e7411\u6708\u5b8c\u6210\u5165\u7ec4\uff0c\u65e8\u5728\u8bc4\u4f30BRII-179\u4f5c\u4e3a\u6cbb\u6108\u65b9\u6848\u4e2d\u6fc0\u6d3bHBV\u7279\u5e94\u6027\u514d\u75ab\u7684\u4e00\u90e8\u5206\uff0c\u5e76\u5c06\u5176\u4f5c\u4e3a\u4e00\u79cd\u5de5\u5177\uff0c\u7528\u4e8e\u8bc6\u522b\u514d\u75ab\u5e94\u7b54\u60a3\u8005\uff0c\u4ee5\u63d0\u9ad8\u529f\u80fd\u6027\u6cbb\u6108\u7684\u53ef\u80fd\u6027\u3002\u817e\u76db\u535a\u836f\u7684\u5f00\u53d1\u5408\u4f5c\u4f19\u4f34Vir Biotechnology\u57282024\u5e7411\u6708AASLD\u5e74\u4f1a\u4e0a\u516c\u5e03\u4e86\u51762\u671f<a href=\"https:\/\/investors.vir.bio\/news\/news-details\/2024\/Vir-Biotechnology-Announces-Positive-End-of-Treatment-Results-for-Tobevibart-and-Elebsiran-Combinations-in-Chronic-Hepatitis-B-from-the-MARCH-Study-at-AASLD-The-Liver-Meeting\/default.aspx\" target=\"_blank\" rel=\"noopener\">MARCH<\/a>\u7814\u7a76\u548c<a href=\"https:\/\/investors.vir.bio\/news\/news-details\/2024\/Vir-Biotechnology-Presents-Positive-Chronic-Hepatitis-Delta-Clinical-Trial-Data-and-Announces-Initiation-of-Phase-3-Registrational-Program\/default.aspx\" target=\"_blank\" rel=\"noopener\">SOLSTICE<\/a>\u7814\u7a76\u6570\u636e.Vir Biotechnology\u8fd1\u671f\u542f\u52a8\u4e863\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8cECLIPSE\u9879\u76ee\u4ee5\u5728\u8bc4\u4f30tobevibart\u4e0eelebsiran\u8054\u5408\u7597\u6cd5\u6cbb\u7597\u6162\u6027\u4e01\u578b\u809d\u708e\uff08CHD\uff09\u30022024\u5e746\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88Vir Biotechnology\u7528\u4e8e\u6cbb\u7597CHD\u7684tobevibart\u548celebsiran \u5feb\u901f\u901a\u9053\u8ba4\u8bc1\uff1b2024\u5e7411\u6708\u83b7\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u5b64\u513f\u836f\u8ba4\u8bc1\uff1b12\u6708\u83b7FDA\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u53caEMA\u7684PRIME\u8ba4\u8bc1\uff08PRIME Designation\uff09\u30022024\u5e745\u6708\uff0ctobevibart\u4e0eelebsiran\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u3002<\/p>\n<p>\u5176\u4ed6\u4e34\u5e8a\u9879\u76ee\u00a0 <\/p>\n<p>\u817e\u76db\u535a\u836f\u6b63\u79ef\u6781\u4e3aHIV\u3001\u591a\u91cd\u8010\u836f\/\u5e7f\u6cdb\u8010\u836f\u611f\u67d3\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u7684\u5019\u9009\u836f\u7269\u5bfb\u6c42\u5916\u90e8\u5408\u4f5c\u3002\u00a0<\/p>\n<p>2024\u5e7410\u6708\uff0c\u817e\u76db\u535a\u836f\u83b7\u5f97\u4e86 NMPA CDE \u7684 IND \u6279\u51c6\uff0c\u5728\u4e2d\u56fd\u5f00\u5c55BRII-693\uff08\u65b0\u578b\u591a\u9ecf\u83cc\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u4e25\u91cd\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\uff09\u76841\u671f\u836f\u4ee3\u52a8\u529b\u5b66\u6865\u63a5\u8bd5\u9a8c\u3002\u6b64\u524d1\u671f\u6570\u636e\u5df2\u4e8e2024\u5e7412\u6708\u53d1\u8868\u4e8e\u300aAntimicrobial Agents and Chemotherapy\u300b\u671f\u520a\uff0c\u652f\u6301\u672a\u6765\u9488\u5bf9\u533b\u9662\u83b7\u5f97\u6027\u7ec6\u83cc\u6027\u80ba\u708e\/\u547c\u5438\u673a\u76f8\u5173\u7ec6\u83cc\u6027\u80ba\u708e\u7684\u5168\u74033\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u3002\u817e\u76db\u535a\u836f\u62e5\u6709BRII-693\u7684\u5168\u7403\u72ec\u5bb6\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u76ca\u3002\u00a0<\/p>\n<p>2024\u5e74\u5ea6\u4f01\u4e1a\u4eae\u70b9\u53ca\u8fd1\u671f\u52a8\u6001\u00a0<\/p>\n<p>\u80a1\u4efd\u56de\u8d2d\uff1a2024\u5e7412\u6708\uff0c\u516c\u53f8\u5ba3\u5e03\u6279\u51c66,000\u4e07\u6e2f\u5143\u80a1\u7968\u56de\u8d2d\u8ba1\u5212\uff08\u5360\u5df2\u53d1\u884c\u80a1\u4efd10%\uff09\uff0c\u5f70\u663e\u4e86\u516c\u53f8\u5bf9\u5176\u524d\u666f\u7684\u4fe1\u5fc3\u3002\u622a\u81f32025\u5e743\u670821\u65e5\uff0c\u516c\u53f8\u5df2\u5728\u9999\u6e2f\u8054\u4ea4\u6240\u56de\u8d2d\u7ea6443.3\u4e07\u80a1\uff0c\u8017\u8d44\u7ea6530\u4e07\u6e2f\u5143\u3002\u8d44\u4ea7\u6536\u8d2d\uff1a2024\u5e7412\u6708\uff0c\u516c\u53f8\u4e0eVBI Vaccines, Inc. \u53ca\u5176\u5173\u8054\u5b50\u516c\u53f8\u7b7e\u7f72\u4e86\u4e00\u9879\u8d44\u4ea7\u8d2d\u4e70\u534f\u8bae\uff0c\u4ee5<span>1,800<\/span>\u4e07\u7f8e\u5143\u603b\u4ef7\u6536\u8d2dBRII-179\u5b8c\u6574\u77e5\u8bc6\u4ea7\u6743\u53ca\u76f8\u5173\u8d44\u4ea7\u3002\u8be5\u534f\u8bae\u53d6\u6d88\u4e86\u672a\u6765\u5411VBI\u652f\u4ed8\u7684\u4e0eBRII-179\u548cPreHevbri TM\u76f8\u5173\u7684\u8d39\u7528\uff0c\u5e76\u89e3\u9664\u4e86\u4e4b\u524d\u4e8e2024\u5e742\u670814\u65e5\u5ba3\u5e03\u7684\u534f\u8bae\u3002\u6b64\u6b21\u6536\u8d2d\u4e3a\u817e\u76db\u535a\u836f\u5e26\u6765\u4e86\u66f4\u591a\u7684\u5546\u4e1a\u83b7\u76ca\uff0c\u540c\u65f6\u786e\u4fdd\u4e86 BRII-179 \u7684\u4e0d\u95f4\u65ad\u4e34\u5e8a\u4f9b\u5e94\u3002\u516c\u53f8\u5c06\u7ee7\u7eed\u5f00\u53d1\u8fd9\u4e00\u8d44\u4ea7\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u7684\u7814\u7a76\u652f\u6301 BRII-179 \u5177\u6709\u63d0\u9ad8 HBV \u60a3\u8005\u5bf9\u6cbb\u7597\u53cd\u5e94\u7684\u6f5c\u529b\u3002<\/p>\n<p>2024\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9<\/p>\n<p>\u622a\u81f32024\u5e7412\u670831\u65e5\uff0c\u6211\u4eec\u7684\u94f6\u884c\u5b58\u6b3e\u3001\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269\u4e3a\u4eba\u6c11\u5e0124.134\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u7684\u4eba\u6c11\u5e0126.614\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e012.48\u4ebf\u5143\u62169.3%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u662f\u7531\u4e8e\u65e5\u5e38\u8425\u8fd0\u53ca\u7814\u53d1\u6d3b\u52a8\u652f\u51fa\u3002\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u5176\u4ed6\u6536\u5165\u4e3a\u4eba\u6c11\u5e011.414\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.637\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4eba\u6c11\u5e012,230\u4e07\u5143\u621613.6%\u3002\u8fd9\u4e3b\u8981\u662f\u7531\u4e8e\u7f8e\u5143\u53ca\u6e2f\u5143\u5b9a\u671f\u5b58\u6b3e\u5229\u7387\u4e0b\u964d\u5bfc\u81f4\u94f6\u884c\u5229\u606f\u6536\u5165\u51cf\u5c11\u4eba\u6c11\u5e012,080\u4e07\u5143\u4ee5\u53ca\u5c31\u4e2d\u56fd\u653f\u5e9c\u8865\u52a9\u786e\u8ba4\u7684\u6536\u5165\u51cf\u5c11\u3002\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u7814\u53d1\u5f00\u652f\u4e3a\u4eba\u6c11\u5e012.498\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e014.027\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e011.529\u4ebf\u5143\u621638.0%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u5f52\u56e0\u4e8e\u62a5\u544a\u671f\u95f4\u7ba1\u7ebf\u6392\u5e8f\u53ca\u7ec4\u7ec7\u4f18\u5316\uff0c\u5bfc\u81f4\u7b2c\u4e09\u65b9\u627f\u5305\u6210\u672c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e017,930\u4e07\u5143\u53ca\u96c7\u5458\u6210\u672c\u51cf\u5c11\u4eba\u6c11\u5e01<span>6,770<\/span>\u4e07\u5143\u3002\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u884c\u653f\u5f00\u652f\u4e3a\u4eba\u6c11\u5e011.532\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.965\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e014,330\u4ebf\u5143\u621622.0%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u5f52\u56e0\u4e8e\u62a5\u544a\u671f\u95f4\u7ba1\u7ebf\u6392\u5e8f\u53ca\u7ec4\u7ec7\u4f18\u5316\uff0c\u5bfc\u81f4\u96c7\u5458\u6210\u672c\u51cf\u5c11\u4eba\u6c11\u5e013,970\u4e07\u5143\u3002\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u671f\u5185\u4e8f\u635f\u4e3a\u4eba\u6c11\u5e015.124\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.844\u4ebf\u5143\u76f8\u6bd4\uff0c\u589e\u52a0\u4e86\u4eba\u6c11\u5e013.28\u4ebf\u5143\u6216177.9%\u3002\u4e8f\u635f\u589e\u52a0\u4e3b\u8981\u5f52\u56e0\u4e8e\u6295\u8d44\u76f8\u5173\u4e8f\u635f\u4eba\u6c11\u5e011.261\u4ebf\u5143\u53ca\u51cf\u503c\u8d39\u7528\u4eba\u6c11\u5e019,030\u4e07\u5143\uff0c\u90e8\u5206\u88ab\u7814\u53d1\u5f00\u652f\u53ca\u884c\u653f\u5f00\u652f\u51cf\u5c11\u6240\u62b5\u9500\u3002\u4e0a\u4e00\u5e74\u5ea6\u5f97\u76ca\u4e8e\u4e00\u6b21\u6027\u51fa\u552e\u8d44\u4ea7\u4ea7\u751f\u7684\u91cd\u5927\u6536\u76ca\u4eba\u6c11\u5e011.318\u4ebf\u5143\u53ca\u4e00\u9879\u80a1\u6743\u6295\u8d44\u7684\u80a1\u4ef7\u4e0a\u5347\u4eba\u6c11\u5e011.292\u4ebf\u5143\uff0c\u800c\u672c\u5e74\u5ea6\u5219\u53d7\u540c\u4e00\u9879\u80a1\u6743\u6295\u8d44\u516c\u5141\u4ef7\u503c\u4e0b\u8dcc\u6240\u5f71\u54cd\u3002<\/p>\n<p>\u7535\u8bdd\u4f1a\u8bae\u4fe1\u606f\u00a0 <\/p>\n<p>\u516c\u53f8\u5c06\u4e8e\u5c06\u4e8e2025\u5e743\u670831\u65e5\u9999\u6e2f\u65f6\u95f4\u4e0a\u53488:30\uff08\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f43\u670830\u65e5\u665a\u95f48:30\uff09\u53ec\u5f00\u7535\u8bdd\u4f1a\u8bae\uff08\u4e2d\u6587\u573a\uff09\u3002\u7ba1\u7406\u5c42\u5c06\u5206\u4eab\u5e74\u5ea6\u66f4\u65b0\u53ca\u57283\u670826\u65e5\u81f330\u65e5\u671f\u95f4APASL\u4f1a\u8bae\u4e0a\u5c55\u793a\u7684\u6570\u636e\u3002\u6240\u6709\u53c2\u4f1a\u8005\u987b\u5b8c\u6210\u4f1a\u8bae\u6ce8\u518c\u3002\u6ce8\u518c\u94fe\u63a5\u8bf7\u70b9\u51fb<a href=\"https:\/\/www.comein.cn\/roadshow\/home\/349413\" target=\"_blank\" 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href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"noopener\">www.briibio.com<\/a>\u3002<\/p>\n<p>\u524d\u77bb\u6027\u58f0\u660e\u00a0 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